Comparison of theophylline concentrations in venous blood and capillary blood in asthmatic children.

1979 ◽  
Vol 25 (10) ◽  
pp. 1837-1839 ◽  
Author(s):  
G S Umstead ◽  
J P Rosen

Abstract Twenty children, five to 16 years old, diagnosed as having asthma, were studied to compare the serum concentrations of theophylline obtained by standard venipuncture with capillary concentrations obtained by finger lancet. The mean theophylline concentration in venous samples was 9.27 mg/L and in capillary samples was 9.26 mg/L. Comparison by the paired t-test showed no statistical difference between kinds of samples. When surveyed as to their preference, nine patients preferred the venous method, five the capillary method, and six had no preference.

2019 ◽  
Author(s):  
Daniel Schiltz ◽  
Natalie Kiermeier ◽  
Dominik Eibl ◽  
Christoph Koch ◽  
Karolina Müller ◽  
...  

BACKGROUND Exact quantification of volumetric changes of the extremities is difficult. There are several direct and indirect methods to assess extremity volume. As water displacement volumetry is rarely viable in a clinical setting and circumference measurements are prone to errors due to poor reproducibility and high inter- and intra-observer variability, an objective and easily reproducible method is indispensable. OBJECTIVE The aim of this study was to establish a standardized method based on 3D scans with defined caudal and cranial landmarks of the lower leg which allows for measurements of exactly the same body area. Furthermore, this study tests the method in terms of reproducibility and evaluates volume changes after surgical therapy in patients suffering from lymphedema. METHODS 3D-scans of the lower limb were performed with a mobile 3D-scanner. Volumetric calculation was done digitally. “Repeatability“ and “Inter-observer reliability” of digital volumetry were tested. Furthermore, the method was applied on 31 patients suffering from chronic lymphedema. ANOVA (analyses of variance) was conducted to compare the digital volumetric measurements. To assess the sensitivity to changes in digital volumetry, the mean volume of 31 patients before and 3 months after therapy were compared by a paired t-Test. RESULTS Calculations of repeatability of the volume based on 20 3D-scans of the same lower leg showed a mean volume of 2,488 ± 0,011 liters (range: 2,470 – 2,510). The mean volume of the 7 measurements of the 3 examiners did not differ significantly (F(2,18) = 1,579, p = .233). The paired t-Test showed a significant mean volume decrease of 375ml (95% CI = 245/505ml) between pre and post treatment (t (30) =5,892, p < .001). CONCLUSIONS 3D-Volumetry is a noninvasive, easy and quick method to assess volume changes of the lower leg. Other than the costs, it is reproducible and precise and therefore ideal for evolution of therapy in lymphedema.


2016 ◽  
Vol 8 (2) ◽  
Author(s):  
Jimmy Koan ◽  
Laurens T. B. Kalesaran ◽  
Heber B. Sapan

Abstract: Available laboratory markers in the early stage of injury are very helpful for the clinicians to predict the diturbances in cellular level concerning prevention of early decompensation, therefore, vital condition of the patient can improve faster. Lactate and leucocyte levels are assumed as sensitive markers of metabolic changes that occur at the time of injury. This study aimed to obtain the changes of lactate and leukocyte levels in multitraumatic patients after resusitation at Prof. Dr. R. D. Kandou Hospital Manado from August to September 2015. This was an observational analytical study. The results showed that there were 36 multitraumatic patients in this study, consisted of 27 males and 9 females. One patient died during this study. The mean decrease of blood lactate was 1.4611 mmol/L, meanwhile, of leukocytes was 5582.2000/mm3. The paired T test showed very significant changes of blood lactate and leukocyte levels (P < 0.001) after resusitation. Conclusion: Achievement of resusitation and improvement in cellular level could be monitored by using lactate and leukocyte levels after resusitation of multitraumatic patients although the definitive aim of the trauma was not final yet.Kata kunci: lactate, leukocyte, multitraumatic patientsAbstrak: Tersedianya penanda laboratorik pada fase awal cedera dapat memudahkan klinisi memrediksi kelainan yang terjadi di tingkat sel untuk mencegah terjadinya fase dekompensasi secara dini sehingga dapat memperbaiki kondisi vital pasien dengan segera. Kadar laktat dan jumlah leukosit telah lama dianggap sebagai salah satu penanda yang sensitif terhadap perubahan metabolisme yang terjadi saat cedera. Penelitian ini bertujuan untuk mengetahui perubahan nilai serum laktat dan leukosit darah yang terjadi pada pasien multitrauma setelah penanganan di RSUP Prof. Dr. R. D. Kandou Manado sejak bulan Agustus sampai dengan September 2015. Jenis penelitian ini observasional analitik dengan desain potong lintang. Hasil penelitian memperlihatkan terdapat 36 pasien multitrauma, terdiri dari 27 laki-laki dan 9 perempuan. Selama penelitian didapatkan 1 pasien meninggal saat penanganan. Pada pasca penanganan, rerata penurunan nilai asam laktat darah sebesar 1,4611 mmol/L dan nilai leukosit sebesar 5582,2000/mm3. Hasil uji T berpasangan memperlihatkan perubahan nilai laktat darah dan leukosit pasca penanganan yang sangat bermakna (P < 0,001). Simpulan: Tercapainya resusitasi dan perbaikan di tingkat sel dapat dimonitor dari nilai laktat dan leukosit darah pasca penanganan pasien multitrauma walaupun penanganan belum sampai pada tujuan definitif trauma.Kata kunci: asam laktat, leukosit, multitrauma


2019 ◽  
Vol 10 (2) ◽  
Author(s):  
Nurul Afifah

This present study was quasi experiment research. This study aimed to find out whether or not there is any the improvement of the students’ reading comprehension by using buzz group technique. The population of the study was all the eighth grade students of SMP SENTOSA BAKTI BATURAJA in Academic Year 2019/ 2020. The sample was taken by using cluster random sampling. The sample is divided by two experimental class and control group. The try-out was done at VIII. C with 22 respondents. The data was collected by using test. The reliability of the data was taken through Alpha Cronbach. The data were analyzed by using paired T-test of control class and paired t-test of experimental class and independent t-test too. The result showed that from the mean score was 71 improved to be 84, 6 and based on independent T-test the value of T obtained was 8,122 as significant level of 0.05 for 2 tailed testing and degree of freedom (df) was 48 the critical value of T table 3, 425. The value was higher than T table (8,122>3,425) and the value sig, (2 tailed)= 0.000 less than the value of significant level (0.05).  It mean that there was significant improvement the students who was taught by using buzz group technique and those who was not at SMP SENTOSA BAKTI Baturaja. It concluded that Buzz group technique was effective to promote students’ reading comprehension at the Eighth Grade students of SMP SENTOSA BAKTI BATURAJA.


2018 ◽  
Vol 51 (4) ◽  
pp. 173
Author(s):  
Vita Previa Indirayana ◽  
Gita Gayatri ◽  
N. R. Yuliawati Zenab

Background: Model analysis constitutes an essential aspect of orthodontic diagnostic practice. Pavan has developed an application to simplify the mathematical calculations employed in orthodontic model analysis. Purpose: This study was conducted to obtain the differences in results and time periods of model analysis using conventional means and iModelAnalysis. Methods: The research represented a comparative analytic study. The populations comprised dental casts dating from 2014 in the Orthodontics Laboratory of Padjadjaran University. The samples comprised 31 dental casts which were subjected to a total sampling method consisting of two treatments; a conventional method calculation and one using iModelAnalysis. A normality test was conducted and processed using a paired t-test with α=0.05. Results: The means of arch length discrepancies were 1.64±2.63 mm and 1.37±3.07 mm for the conventional methods and 1.65±2.43mm and 1.42±3.04mm for iModelAnalysis. The results of a Bolton analysis for conventional methods were 78.05±2.69% and 91.93±1.29%, while those for iModelAnalysis were 77.91±2.70% and 91.96±2.13%. A Howes analysis of conventional methods produced a result of 45.56±2.83%, while for an iModelAnalysis one of 45.56±2.85%. Pont analysis for conventional methods was 39.35±0.04 mm and 49.17±2.55 mm, while for iModelAnalysis it was 39.35±0.07 mm and 49.19±2.57mm. The mean of the duration of analysis using conventional methods was 1703.81±56.46 seconds, while for iModelAnalysis it was 990.06±34.87 seconds. A normality test confirmed that the data was normally distributed (p>0.05). The results of a paired sample t-test with p>0.05 showed that there was no significant difference between the results of each analysis, while there was significant difference in the time period of analysis. Conclusion: There was no difference in the analysis results. However, there was difference in the time period of analysis between conventional methods and that of iModelAnalysis.


2017 ◽  
Vol 3 (6) ◽  
pp. 693-696
Author(s):  
Muhaji Muhaji ◽  
Bedjo Santoso ◽  
Putrono Putrono

Background: Endotracheal suctioning is one of the common supportive measures in intensive care units (ICU), which may be related to complications such as hypoxia. However, a questionable efficacy is still identified to choose suctioning pressure between 130 mmHg and 140 mmHg that is effective for patients with endotracheal tube.Objective: To compare the effectiveness of 130 mmHg and 140 mmHg suctioning pressure on oxygen saturation in patients with endotracheal tube.Methods: This research used a quasy experimental design with pretest and posttest group. The study was conducted from 31 January to 1 March 2017 in the Hospital of Panti Wilasa Citarum and Hospital of Roemani Muhammadiyah Semarang. There were 30 samples recruited using consecutive sampling, with 15 assigned in the 130 mmHg and 140 mmHg suctioning pressure group. Pulse oximetry was used to measure oxygen saturation. Paired t-test and Independent t-test were used for data analysis.Results: Findings showed that there was a statistically significant effect of 130 and 140 mmHg suctioning pressure on oxygen saturation in patients with ETT with p-value <0.05. There was a significant mean difference of oxygen saturation between 130 mmHg and 140 mmHg suctioning pressure group with p-value 0.004 (<0.05). The mean difference of oxygen saturation between both groups was 13.157.Conclusion: The 140 mmHg suctioning pressure is more effective compared with 130 mmHg suctioning pressure in increasing oxygen saturation in patients with ETT.


2019 ◽  
Vol 2 (1) ◽  
pp. 93-104
Author(s):  
Ardayati Ardayati ◽  
Herlina Herlin

The problem of this research was to find out whether or not it is significantly effective to improve reading comprehension through Concept Oriented Reading Instruction (CORI) Strategy to the Eighth Grade Students of SMP Negeri 13 Lubuklinggau in the academic year 2016/2017. The strategy applied was pre experimental method with one group pretest-posttest design.. The sample was taken through cluster random sampling. The result was VIII.2 class with the total number of 28 students. The data were collected through test consisted of 25 items of multiple choices. The data were analyzed through four techniques: 1) Students’ Individual Score, 2) Minimum Mastery Criteria, 3) Normality and 4) Paired t-test calculation. The result of this study: (1) The mean students’ score in the pre-test was 64.00, (2) The mean score of post-test was 76.00 and (3) the result of paired t-test was 11.43, which was higher than 1.703 value of the t-table of 27 (28-1) with 95% significant level for one tailed-test. In this research the researcher formulated two hypotheses. They were null hypothesis (Ho) and alternative hypothesis (Ha). Based on the result of the paired t-test calculation showed that the null hypothesis (Ho) was rejected and the alternative hypothesis (Ha) was accepted. It meant that it was significantly effective to Teach Reading Comprehension through Concept Oriented Reading Instruction (CORI) Strategy to the Eighth Grade Students of SMP Negeri 13 Lubuklinggau in the academic year of 2016/2017


1991 ◽  
Vol 66 (3) ◽  
pp. 974-985 ◽  
Author(s):  
H. Nishijo ◽  
R. Norgren

1. A total of 51 single neurons was recorded from the pontine parabrachial nuclei of three rats being given sapid stimuli either via intraoral infusions or during spontaneous licking behavior. In 46 neurons, sapid stimuli elicited significant taste responses; of these, 28 responded best to NaCl, 15 to sucrose, 2 to citric acid, and 1 to quinine HCl. The remaining five neurons responded significantly only to water. The mean spontaneous rate of taste neurons during the intraoral infusion and licking sessions was 11.1 +/- 1.1 and 10.8 +/- 1.2 (SE) spikes/s, respectively. 2. Of the 39 neurons tested during both licking and intraoral infusions, four responded significantly only to water via either route. The remaining 35 neurons responded significantly to at least some sapid stimuli. The best-stimulus categories remained the same regardless of the route of fluid delivery (24 NaCl best, 10 sucrose best, 1 citric acid best). When the rats were licking the stimuli, nine taste neurons responded significantly to only one sapid chemical [6 Na specific (Ns) and 3 sucrose specific (Ss)] but were more broadly tuned during intraoral infusions. Conversely, three taste neurons that responded specifically during intraoral infusions (3 Na specific) were not as specific when the animal licked the same fluids. 3. Thirty-five taste neurons were tested via both stimulus routes. These data were compared in three ways. First, for each neuron, the responses elicited during licking and intraoral infusions were compared for each of the four standard sapid stimuli. The Pearson correlation coefficients for the 35 taste neurons ranged from 0.9997 to 0.6785, with a mean at 0.953 +/- 0.012 (SE). The second comparison was between stimulus routes across chemicals. With the use of raw responses, the correlation coefficients for NaCl, sucrose, citric acid, and QHCl ranged from 0.925 to 0.778 (t test, P less than 0.0001). With the activity elicited by water subtracted (corrected responses), the correlation coefficients for NaCl, sucrose, citric acid, and QHCl were 0.900, 0.795, 0.369, and 0.211, respectively. The coefficient for QHCl was not significant (t test, P greater than 0.05). Finally, the mean responses to NaCl, sucrose, and citric acid delivered by both routes were compared and found not to differ (paired t test, P greater than 0.05). 4. In separate hierarchical cluster analyses for the licking and infusion data, the largest cluster in each contained all of the Na-best neurons and the next largest, all of the sucrose-best cells.(ABSTRACT TRUNCATED AT 400 WORDS)


Author(s):  
Zahra Khamverdi1 ◽  
Elmira Najafrad ◽  
Maryam Farhadian

Objectives: Marginal and internal fit of restorations are two important clinical factors for assessing the quality and durability of computer-aided design/computer-aided manufacturing (CAD/CAM)-fabricated monolithic zirconia restorations. The purpose of this study was to evaluate the marginal and internal fit of CAD/CAM zirconia crowns with two different scanners (i3D scanner and 3Shape D700). Materials and Methods: Twelve extracted sound human posterior teeth were prepared for full zirconia crowns. Two different extraoral scanners namely i3D scanner and 3Shape D700 were used to digitize type IV gypsum casts poured from impressions. The crowns were milled from presintered monolithic zirconia blocks by a 5-axis milling machine. The replica technique and MIP4 microscopic image analysis software were utilized to measure the marginal and internal fit by a stereomicroscope at ×40 magnification. The collected data were analyzed by paired t-test. Results: The mean marginal gap was 203.62 μm with 3Shape D700 scanner and 241.07 μm with i3D scanner. The mean internal gap was 192.30 μm with 3Shape D700 scanner and 196.06 μm with i3D scanner. The results of paired t-test indicated that there was a statistically significant difference between the two scanners in marginal fit (P=0.04); while, there was no statistically significant difference in internal fit (P=0.761). Conclusion: Within the limitations of this study, the results showed that type of extraoral scanner affected the marginal fit of CAD/CAM fabricated crowns; however, it did not have a significant effect on their internal fit.


Author(s):  
LRP Wijaya ◽  
D Pentiana ◽  
EY Puspitasari

The objective of this research was to test perceptions of accounting graduates fromPoliteknik Negeri Lampung and employers to various competencies and their attributes. Theperceptions of accounting graduates and employers were ranked to produce competence types(attributes) that were categorized into two skills; generic and technical skills. The researchrespondents were graduates of the Accounting Study program in Politeknik Negeri Lampungand representatives from employer or company managements. The hypothesis was tested witha one-tailed paired t-test and ranking was done based on the mean score from each skill. Theresearch result showed that the accounting graduates considered generic skill was overall moreimportant than technical skill, even though individually technical skill was more important thangeneric skill and it was proven by the highest mean score at technical skill according to theaccounting graduates‟ perceptions. This research also found that overall the employerconsidered generic skill was more important than technical skill, even though individuallytechnical skill obtained the highest mean score according to employer perceptions.


2021 ◽  
Vol 7 (1) ◽  
pp. 8-11
Author(s):  
Novita Hasiani Simanjuntak

Background: Dengue Hemorrhagic Fever (DHF) in Indonesia is a “re-emerging infectious disease”. DHF can be prevented by vector control. Human behavior is very influential on dengue vector control, namely the cleanliness of the house and activities. In 2017, DHF cases in Indonesia were 59,047 cases. In North Sumatra Province, there were 5,327 cases, in Medan City as many as 1216 cases, with Medan Deli District as the sub-district with the most cases, with 100 cases. Objective: This study aims to see the improvement of mother's behavior by using the roleplay method and simulation games. Methods: The research is a quasi-experimental non-equivalent group design. The target population is mothers who live in Medan Deli District. The selection of research subjects by purposive sampling, with the number of subjects in each group is 15 people. This study uses the method of role play and games as a comparison method, with a questionnaire as a measuring tool. Paired t-test to see the increase in the mean of each group, and unpaired t-test to see the difference in the mean value. Results: The results of the paired t-test data analysis found that these two methods showed significant results, with p values ​​of 0.000 and 0.001 with a mean increase in the role play method of 1.40 and the game method of 1.53. The unpaired t-test was found to have a significant difference between the average post-test scores between the role play method and the game method, the mean post-test score for the role-play method was found to be lower than the post-test score for the game method. Conclusions: Counseling using the role play method and games provides significant results in increasing maternal behavior about DHF. The game method shows a greater average increase than the role play method.


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