Antimicrobial Activity of Indigofera suffruticosa

Various organic and aqueous extracts of leaves ofIndigofera suffruticosaMill (Fabaceae) obtained by infusion and maceration were screened for their antibacterial and antifungal activities. The extracts were tested against 5 different species of human pathogenic bacteria and 17 fungal strains by the agar-solid diffusion method. Most of the extracts were devoid of antifungal and antibacterial activities, except the aqueous extract of leaves ofI. suffruticosaobtained by infusion, which showed strong inhibitory activity against the Gram-positive bacteriaStaphylococcus aureuswith a minimal inhibitory concentration (MIC) of 5000 µg ml−1. The MIC values to dermatophyte strains were 2500 µg ml−1 againstTrichophyton rubrum(LM-09, LM-13) andMicrosporum canis. This study suggests that aqueous extracts of leaves ofI. suffruticosaobtained by infusion can be used in the treatment of skin diseases caused by dermatophytes.

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Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities

Journal of Chemistry ◽

10.1155/2013/149693 ◽

2013 ◽

Vol 2013 ◽

pp. 1-7 ◽

Cited By ~ 8

Author(s):

Serkan Yavuz ◽

Hilal Yıldırım

Keyword(s):

Inhibitory Concentration ◽

Antibacterial Activities ◽

Klebsiella Pneumonia ◽

Gram Negative Bacteria ◽

Ferrocene Derivatives ◽

Antifungal Activities ◽

Gram Positive Bacteria ◽

Antibacterial And Antifungal Activities ◽

Elemental Analyses ◽

Antibacterial And Antifungal

In the present study, some novel ferrocene derivatives carrying urea, thiourea, and sulfonamide groups were synthesized, and all compounds were characterized by spectral and elemental analyses. These compounds were screened for their antibacterial activities and also their minimum inhibitory concentration (MIC) against Gram-positive bacteria (Staphylococcus aureusandBacillus subtilis) and Gram-negative bacteria (Klebsiella pneumoniaandEscherichia coli) and antifungal activities againstSaccharomyces cerevisiaeandCandida albicans. Amongst the tested compounds,4b,4c,5b, and6bdisplayed excellent antimicrobial activity.

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Antibacterial Activities of Xanthium Strumarium L.

Journal of Natural History Museum ◽

10.3126/jnhm.v29i0.19039 ◽

2018 ◽

Vol 29 ◽

pp. 70-77 ◽

Cited By ~ 2

Author(s):

Anjana Devkota ◽

Ritu Kumari Das

Keyword(s):

Antibacterial Activity ◽

Pathogenic Bacteria ◽

Antibacterial Activities ◽

Diffusion Method ◽

Xanthium Strumarium ◽

Distilled Water ◽

Leaf Extracts ◽

Gram Positive ◽

Gram Negative ◽

Gram Positive Bacteria

Antibacterial activities of Xanthium strumarium L. (Asteraceae) was carried out in laboratory. Distilled water and methanol extracts of the leaves of plant was prepared. The antibacterial activity was studied against six pathogenic bacteria, three gram negative: Klebsiella pneumoniae (ATCC 15380), Proteus mirabilis (ATCC 49132), Escherichia coli (ATCC 25922) and three gram positive: Bacillus subtilis (ATCC 6633), Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 25932) at different concentrations (50 mg/ml, 100 mg/ml, 150 mg/ml, 200 mg/ ml, 250 mg/ml) of leaf extracts of X. strumurium. The phytochemical screening depicted the presence of terpenoids, saponins, flavonoids, tannins and alkaloids. The antibacterial activity of extracts was determined by disc diffusion method and zone of inhibition (ZOI) was measured. Gram negative bacteria was found more resistant than gram positive bacteria. The most susceptible bacterium was S. aureus while the most resistant bacterium was E. coli. Methanolic extract was found more effective than distilled water. These findings suggest that extracts obtained from leaves of X. strumurium possess biobactericidal potential, which can suitably be exploited for making antibacterial drugs.J. Nat. Hist. Mus. Vol. 29, 2015, Page: 70-77

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Studies of Antimicrobial Activity of 2',4',5'- and 2',3',4'-Trimethoxy Flavanones

Journal of Scientific Research ◽

10.3329/jsr.v8i2.26622 ◽

2016 ◽

Vol 8 (2) ◽

pp. 209-216

Author(s):

A. Rahim ◽

R. Ali ◽

A. Islam

Keyword(s):

Pathogenic Bacteria ◽

Sclerotium Rolfsii ◽

Antibacterial Activities ◽

Diffusion Method ◽

Disc Diffusion ◽

Disc Diffusion Method ◽

Filter Paper Disc ◽

Antibacterial And Antifungal ◽

Paper Disc

2',4',5'- and 2',3',4'-trimethoxy flavanones have been synthesized starting with 2-hydroxyacetophone and substituted aldehyde. Antibacterial activities of the flavanones have been tested along with their corresponding chalcones against two human pathogenic bacteria (Streptococcus-b-haemolyticus and Klebsiella sp. (G-)). Antifungal activities of the flavanones have also been investigated against two plants pathogenic mold fungi (Rhizactonia solani Sclerotium rolfsii). The structures of the synthesized compounds have been characterized with the help of UV, IR and 1H NMR and 13C-NMR spectra. The antibacterial and antifungal screening were performed in vitro by the filter paper disc diffusion method and poisoned food technique. The flavanones showed antibacterial activity while no activity was observed to their corresponding chalcones against the tested bacteria. On the other hand, chalcones and their corresponding flavanones both showed fungicidal activities.

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Antibacterial and Antifungal Evaluation of Chloroflavones

Journal of Scientific Research ◽

10.3329/jsr.v10i1.33858 ◽

2018 ◽

Vol 10 (1) ◽

pp. 67-76

Author(s):

M. A. Rahim ◽

M. M. H. Bhuiyan ◽

M. M. Matin ◽

M. R. Alam

Keyword(s):

Pathogenic Bacteria ◽

Salmonella Typhi ◽

Aspergillus Ochraceus ◽

Diffusion Method ◽

Dilution Method ◽

Significant Activity ◽

Filter Paper Disc ◽

Antibacterial And Antifungal Activities ◽

Antibacterial And Antifungal

Two chloroflavones, 6 and 7 along with their corresponding chalcones, 4 and 5 have been tested for antibacterial and antifungal activities against six human pathogenic bacteria viz. Bacillus cereus (G+), Staphylococcus aureus (G+), Escherichia coli (G-), Vibrio choloriae (G-), Pseudomonas aeruginosa (G-), and Salmonella typhi (G-), and four plant as well as mold fungi viz. Aspergillus flavus, Aspergillus ochraceus, Aspergillus niger and Rhizopus spp.. The antibacterial and antifungal screens of the synthesized compounds were performed in vitro by the filter paper disc diffusion method and the poisoned food technique, respectively. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of these synthesized compounds in comparison to ampicillin were also determined by broth micro-dilution method. Some of them were found to possess significant activity, when compared to standard drugs.

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Caralluma europaea (Guss.) N.E.Br.: Anti-Inflammatory, Antifungal, and Antibacterial Activities against Nosocomial Antibiotic-Resistant Microbes of Chemically Characterized Fractions

Molecules ◽

10.3390/molecules26030636 ◽

2021 ◽

Vol 26 (3) ◽

pp. 636

Author(s):

Fatima Ez-Zahra Amrati ◽

Mohammed Bourhia ◽

Hamza Saghrouchni ◽

Meryem Slighoua ◽

Andriy Grafov ◽

...

Keyword(s):

Bioactive Compounds ◽

Chemical Characterization ◽

Antibacterial Activities ◽

Antibiotic Resistant ◽

Traditional Medicines ◽

Gram Positive Bacteria ◽

Antibacterial And Antifungal Activities ◽

The Family ◽

Anti Inflammatory ◽

Antibacterial And Antifungal

Caralluma europaea (Guss.) N.E.Br.: (C. europaea) is a wild medicinal plant belonging to the family Apocynaceae. It is commonly used in traditional medicines for treating several diseases. The present work aims to evaluate the anti-inflammatory, antibacterial, and antifungal potentials of C. europaea fractions including hydro ethanol (ET CE), n-butanol (But CE), and polyphenol (Poly CE). The chemical composition of hydroethanol, n-butanol, and polyphenol-rich fractions from C. europaea were determined using GC-MS after silylation. The anti-inflammatory effect of hydroethanol, n-butanol, and polyphenol-rich fractions was studied by carrageenan-induced paw edema. Antibacterial and antifungal activities of hydroethanol, n-butanol, and polyphenol-rich fractions against Gram-positive bacteria, Gram-negative bacteria, and yeasts were assessed using the disc diffusion and micro-dilution assays. The findings of the chemical characterization affirmed the presence of interesting bioactive compounds in C. europaea fractions. The polyphenol-rich fraction was the best inhibitor of edema by75.68% after 6 h of treatment. The hydroethanol fraction was the most active against both bacteria and yeasts. This study contributes to society as it provides potential bioactive compounds in C. europaea extract, which may help in fighting nosocomial antibiotic-resistant microbes.

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An Invitro Study: Antioxidant, Phytochemical Analysis and Antimicrobial Activities of Achranthes aspera

International Journal of Advanced Research in Science, Communication and Technology ◽

10.48175/ijarsct-2184 ◽

2021 ◽

pp. 268-277

Author(s):

Masiraben Vahora ◽

Falaknaaz Shaikh

Keyword(s):

Radical Scavenging Activity ◽

Radical Scavenging ◽

Antibacterial Activities ◽

Antimicrobial Activities ◽

Positive Control ◽

Diffusion Method ◽

Phytochemical Analysis ◽

Antibacterial And Antifungal Activities ◽

Fusarium Sp ◽

Antibacterial And Antifungal

Medicaments, plants and plant-based are the basis of many of the modern pharmaceuticals we use today for our various purposes. The aim of the present study was to evaluate the antioxidant, phytochemical and antibacterial and antifungal activities of the Achyranthes aspera plant extract in different organic solvents. The radical scavenging activity of the different extracts of root, stem, leaf, and seed were evaluated by DPPH assay and the antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa, and antifungal activity against Fusarium sp. and Aspergillus niger was studied by Agar well cut diffusion method. All of the extracts exhibited different antioxidant and antibacterial activities and the activities varied from solvent to solvent, and the activities are concentrated. The antioxidant and antimicrobial activities were compared with the positive control Ascorbic acid and Cefuroxime. A qualitative phytochemical analysis was carried out and found to possess bioactive compounds like alkaloids, glycosides, terpenoids, steroids, flavonoids, tannins.

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Chemical composition, antibacterial and antifungal activity of the essential oils of Cotinus coggygria from Serbia

Journal of the Serbian Chemical Society ◽

10.2298/jsc0711045n ◽

2007 ◽

Vol 72 (11) ◽

pp. 1045-1051 ◽

Cited By ~ 21

Author(s):

Miroslav Novakovic ◽

Ivan Vuckovic ◽

Pedja Janackovic ◽

Marina Sokovic ◽

Anka Filipovic ◽

...

Keyword(s):

Essential Oils ◽

Diffusion Method ◽

Disc Diffusion Method ◽

Gram Positive Bacteria ◽

Antibacterial And Antifungal Activities ◽

Microdilution Method ◽

Antifungal Potential ◽

Antibacterial And Antifungal ◽

Cotinus Coggygria ◽

Commercial Fungicide

Essential oils from leaves with young branches of Cotinus coggygria Scop. from two localities in Serbia (Deliblatska pescara and Zemun), obtained by hydrodistillation, were analyzed by GC-MS. Thirty-one component were identified from both oils and among them monoterpenic hydrocarbons were the dominant class (87.4 and 93.1 %). The dominant constituent in both essential oils was limonene (47.0 and 39.2 %). Both oils were also tested for antibacterial and antifungal activities. In comparison to streptomycin, both oils showed slightly higher activity (against most Gram-positive bacteria) in the disc diffusion method and slightly lower activity when the microdilution method was employed. They also exhibited antifungal potential higher than that of the commercial fungicide bifonazole.

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Synthesis and Antimicrobial Studies of Some 4-(Substituted)-Ethanoylamino-3-Mercapto-5- (4-Substituted) Phenyl-1,2,4-Triazoles

Dhaka University Journal of Pharmaceutical Sciences ◽

10.3329/dujps.v11i1.12481 ◽

2012 ◽

Vol 11 (1) ◽

pp. 7-18 ◽

Cited By ~ 3

Author(s):

Neeraj Upmanyu ◽

Sanjay Kumar ◽

Kamal Shah ◽

Pradeep Mishra

Keyword(s):

Antimicrobial Agents ◽

Diffusion Method ◽

Mass Spectral ◽

Gram Positive Bacteria ◽

Chemical Structures ◽

Antibacterial And Antifungal Activities ◽

Antimicrobial Studies ◽

Diverse Application ◽

Substituted Benzoic Acids ◽

Antibacterial And Antifungal

Triazoles and triazoles with different substituent groups are found to possess diverse application in the field of medicine and industry. A series of 4-(substituted) ethanoylamino-3-mercapto-5-(4-substituted) phenyl-1,2,4- triazoles were synthesized as novel antimicrobial agents starting from different 4-substituted benzoic acids. The chemical structures of these newly synthesized compounds were elucidated by IR, 1H NMR, 13C NMR, FAB+-mass spectral data and elemental analyses. The antimicrobial activity of title compounds were examined against two gram positive bacteria (Staphylococcus aureus, Bacillus subtilis), two gram negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and three fungi (Candida albicans, Aspergillus niger and Fusarium oxysporum) using disc diffusion method. Some of the compounds bearing methoxy group exhibited moderate to good antibacterial and antifungal activities. DOI: http://dx.doi.org/10.3329/dujps.v11i1.12481 Dhaka Univ. J. Pharm. Sci. 11(1): 7-18, 2012 (June)

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Antibacterial activity of aqueous and ethanolic extracts of Portulaca oleracea L. and Taraxacum mongolicum Hand.-Mazz against pathogenic bacteria of cow mastitis

Indian Journal of Animal Research ◽

10.18805/ijar.5960 ◽

2015 ◽

Cited By ~ 3

Author(s):

Shumin Sun ◽

Weichang Dai ◽

Hansong Yu ◽

Yuhua Wang ◽

Xuelin Wang ◽

...

Keyword(s):

Escherichia Coli ◽

Antibacterial Activity ◽

Pathogenic Bacteria ◽

Bacterial Resistance ◽

Antibacterial Activities ◽

Portulaca Oleracea ◽

Diffusion Method ◽

Aqueous Extracts ◽

Streptococcus Dysgalactiae ◽

Ethanolic Extracts

As the problems of bacterial resistance and safety of dairy products have become more prominent, alternative medicine for antibiotics in treating cow mastitis is needed. In the present study, antibacterial activity of aqueous and ethanolic extracts of Portulaca oleracea L. and Taraxacum mongolicum Hand.-Mazz against the main pathogenic bacteria (Escherichia coli, Staphylococcus aureus, Streptococcus agalactiae and Streptococcus dysgalactiae) of cow mastitis was evaluated using disc diffusion method. The results showed that aqueous and ethanolic extracts of the two herbs both could inhibit the four pathogenic bacteria of cow mastitis at different level. All extracts of the two herbs displayed the highest antibacterial activities against Escherichia coli than other bacteria. For Portulaca oleracea L., ethanolic extracts had higher antibacterial activities than aqueous extracts except for against Escherichia coli. However, for Taraxacum mongolicum Hand.-Mazz, ethanolic extracts had lower antibacterial activities than aqueous extracts. These results indicate that extracts of Portulaca oleracea L. and Taraxacum mongolicum Hand.-Mazz have the potential to be used in treating cow mastitis.

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Assay of Antibacterial and Antifungal Activity of Silver Nanoparticles Accompanying Different Impurities

10.21203/rs.3.rs-392550/v1 ◽

2021 ◽

Author(s):

Mohsen A. Sayed ◽

Asmaa A. H. El-Bassuony ◽

H. K. Abdelsalam

Keyword(s):

Silver Nanoparticles ◽

Annealing Temperature ◽

Clinical Medicine ◽

Antibacterial Activities ◽

Diffusion Method ◽

Dilution Method ◽

Gram Negative Bacteria ◽

Antimicrobial Compounds ◽

Gram Positive Bacteria ◽

Antibacterial And Antifungal

Abstract No doubt that antimicrobial compounds such as antibiotics are the basic tools in clinical medicine. Increase in antimicrobial resistance may cause several human diseases. The potential of drugs and other agents can be improved by using nanoparticles. Wide use of antimicrobial compounds resulted in formation of resistance in microbes. There is demand to look for novel agents for therapy. Novel silver nanoparticles accompanied different impurities were assayed against Streptococcus pyogenes and Staphylococcus aureus (Gram-positive bacteria), Pseudomonas aeruginosa and Proteus mirabilis (Gram-negative bacteria). In addition to Aspergillus niger, A. terrus, Penicillium cluclauni and Rhizopus stolonofer fungi. Four Candida spp. were also assayed: C. krusei, C. famata, C. parapsilosis and C. utiliz. The method which applied in assaying these microorganisms was diffusion method. Dilution method was obtained for the tested nanoparticles to find the minimum inhibitory concentration MIC. The annealing temperature of the tested nanoparticles affected on antifungal and antibacterial activities. It was found that the preparation of nanoparticles at room temperature gave higher activities against tested antimicrobial than that at high temperatures.

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