scholarly journals COVID-19 related thrombi in ascending and descending thoracic aorta with peripheral embolization: a case report

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Jan W Buikema ◽  
Folkert W Asselbergs ◽  
Janneke Tekstra
Keyword(s):  
Thoracic Aorta ◽  
Thrombus Formation ◽  
The Body ◽  
Angiotensin Converting Enzyme 2 ◽  
Peripheral Embolization ◽  
Increased Risk ◽  
Life Threatening ◽  
Thrombotic Complications ◽  
The Right ◽  
The Brain

Abstract Background COVID-19 (severe acute respiratory syndrome coronavirus 2) infected patients have increased risk for thrombotic events, which initially may have been under recognized. The existence of cardiovascular emboli can be directly life threatening when obstructing the blood flow to vital organs such as the brain or other parts of the body. The exact mechanism for this hypercoagulable state in COVID-19 patients yet remains to be elucidated. Case summary A 72-year-old man critically ill with COVID-19 was diagnosed with a free-floating and mural thrombus in the thoracic aorta. Subsequent distal embolization to the limbs led to ischaemia and necrosis of the right foot. Treatment with heparin and anticoagulants reduced thrombus load in the ascending and thoracic aorta. Discussion One-third of COVID-19 patients show major thrombotic events, mostly pulmonary emboli. The endothelial expression of angiotensin-converting enzyme-2 receptors makes it feasible that in patients with viraemia direct viral-toxicity to the endothelium of also the large arteries results in local thrombus formation. Up to date, prophylactic anticoagulants are recommended in all patients that are hospitalized with COVID-19 infections to prevent venous and arterial thrombotic complications.

scholarly journals Cannabis, a complex plant: different compounds and different effects on individuals

2012 ◽  
Vol 2 (6) ◽  
pp. 241-254 ◽  
Author(s):  
Zerrin Atakan
Keyword(s):  
Endocannabinoid System ◽  
The Body ◽  
Vulnerability Factors ◽  
Negative Effects ◽  
Biochemical Basis ◽  
Neurotransmitter System ◽  
Increased Risk ◽  
Opposing Effects ◽  
Available Information ◽  
The Brain

Cannabis is a complex plant, with major compounds such as delta-9-tetrahydrocannabinol and cannabidiol, which have opposing effects. The discovery of its compounds has led to the further discovery of an important neurotransmitter system called the endocannabinoid system. This system is widely distributed in the brain and in the body, and is considered to be responsible for numerous significant functions. There has been a recent and consistent worldwide increase in cannabis potency, with increasing associated health concerns. A number of epidemiological research projects have shown links between dose-related cannabis use and an increased risk of development of an enduring psychotic illness. However, it is also known that not everyone who uses cannabis is affected adversely in the same way. What makes someone more susceptible to its negative effects is not yet known, however there are some emerging vulnerability factors, ranging from certain genes to personality characteristics. In this article we first provide an overview of the biochemical basis of cannabis research by examining the different effects of the two main compounds of the plant and the endocannabinoid system, and then go on to review available information on the possible factors explaining variation of its effects upon different individuals.

scholarly journals Necrotizing fasciitis with group A Streptococci and Eggerthella lenta as a complication of Varicella in a child – case presentation –

2014 ◽  
Vol 20 (1) ◽  
pp. 35-39
Author(s):  
Cambrea Simona Claudia ◽  
Ilie Maria Margareta ◽  
Carp Dalia Sorina ◽  
Ionescu C.
Keyword(s):  
Necrotizing Fasciitis ◽  
Severe Disease ◽  
The Body ◽  
Group A Streptococci ◽  
Threatening Condition ◽  
Life Threatening ◽  
Group A ◽  
The Right ◽  
Surgery Department ◽  
Short Time

ABSTRACT Necrotizing fasciitis is a life threatening condition that can be quickly spread through the flesh surrounding the muscle. The disease can be polymicrobial, or caused by group A beta hemolytic Streptococci, or by Clostridium spp. We present a case of a 7 years old girl, which was hospitalized in Children Infectious Diseases Department in a 7th day of chickenpox (hematic crusts all over the body), high fever, asthenia, vomiting, oligoanuria, and tumefaction, pain and functio lessa in the right thigh. In a very short time in the right thigh swelling, edema and congestion have increased gradually, and in the third highest middle thigh the ecchymotic areas appeared evolving towards bubbles and blisters which included the right thigh and calf. After excluding the diagnosis of thrombophlebitis was raised suspicion of necrotizing fasciitis. CT pelvic scan evidenced pelvic asymmetry by maximus and medium right gluteal muscles swelling with important inflammatory infiltrate extended laterally in the subcutaneous adipose tissue. In blood culture was isolated Eggerthella lenta, and from throat swab was isolated group A Streptococci. Treatment consists of a combination of antibiotics associated with intravenous immunoglobulin administration. Despite medical treatment evolution worsened and required transfer in a pediatric surgery department where emergent surgical debridement associated with intensive antibiotic therapy was done. After this intervention evolution was slowly favorable without major limb dysfunction. Polymicrobial necrotizing fasciitis is a severe disease, which if recognized early can have a favorable outcome.

*Grown MD CBD gummies Where To buy? Scam Pills | Alert* v1

2022 ◽  
Author(s):  
health not provided
Keyword(s):  
Circulatory System ◽  
Grape Seed ◽  
The Body ◽  
Secondary Effects ◽  
Psychological Issues ◽  
Primary Element ◽  
Grape Seed Oil ◽  
The Right ◽  
Sleeping Disorder ◽  
The Brain

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CBD extricates are picked straightforwardly from the homesteads and tried in the labs for adding to the method involved with assembling these tablets. These chewy candies may not contain: Counterfeit additives Tones or flavors Gluten Soy Sugars Fabricated materials These containers are alright for guys just as females. They may not cause secondary effects or skin sensitivities in the body. Also, these chewy candies are made in clean assembling conditions. Click Here to Get with an Exclusive Discount & Effective Price How do these chewy candies function in the body? GrownMD CBD Gummiesmight upgrade the functioning arrangement of endocannabinoids. They might blend well in the circulatory system and help to deliver torment in the body. You may likewise get alleviation from stress, tension, and restlessness subsequent to taking these cases. They might keep an appropriate equilibrium in the body. You might improve results inside specific weeks in the wake of utilizing these cases. 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CBD concentrates of these cases might assist with delivering exceptional agony in the body. They may likewise lessen the aggravation of joints, back, neck and shoulders. You might get alleviation from aggravation and consuming sensation subsequent to devouring these tablets. The Plant MD organization claims individuals incline toward their chewy candies over comparative items in light of the fact that: The hemp plant from which Plant MD cannabinoid is extricated is filled in natural homesteads in America. The office that produces Plant MD CBD chewy candies claims it has fulfilled all the wellbeing guidelines. Every one of the fixings in the Plant MD Revive Gummies are completely protected and regular. Plant MD CBD chewy candies can be devoured by vegetarians and have no gluten added substances. This item contains Premium Grape Seed Oil collected from natural ranches. The fruity taste of Plant MD Revive CBD chewy candies is interesting to new clients. 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Click Here to Get with an Exclusive Discount & Effective Price You can buy GrownMD CBD Gummies online just from the authority site. You should visit the authority website and fill an internet based structure. In the structure, you ought to compose every one of the subtleties like name, address, email ID, telephone number, city, a state with postal district. Then, at that point, you need to present the structure and pick the strategy for installment. One jug of GrownMD CBD Gummies costs $60.04 on the authority site. To get a rebate, you should arrange the item in a bunch of 3 or 5 containers. Associate Disclosure: The connections contained in this item survey might bring about a little commission to us. Assuming that you select to buy the item prescribed at no extra expense for you. Disclaimer: Kindly comprehend that any exhortation or rules uncovered here are not at all a substitute for sound clinical guidance from an authorized medical care supplier. 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Amyloidosis

2013 ◽  
pp. 1397-1409
Author(s):  
Philip N. Hawkins
Keyword(s):  
Protein Misfolding ◽  
Solid Organ Transplantation ◽  
The Body ◽  
Solid Organ ◽  
Body Protein ◽  
Amyloid Deposits ◽  
Life Threatening ◽  
And Function ◽  
Protein Misfolding And Aggregation ◽  
The Brain

Amyloidosis is a disorder of protein folding in which normally soluble proteins are deposited in the interstitial space as insoluble and remarkably stable fibrils that progressively disrupt tissue structure and function of organs throughout the body. Protein misfolding and aggregation have increasingly been recognized in the pathogenesis of various other diseases, but amyloidosis—the disease directly caused by extracellular amyloid deposition—is a precise term with critical implications for patients with a specific group of life-threatening disorders. Amyloidosis may be acquired or hereditary and the pattern of organ involvement varies within and between types, though clinical phenotypes overlap greatly. Virtually any tissue other than the brain may be directly involved. Although histology remains the diagnostic gold standard, developments in scintigraphy and MRI technology often produce pathognomonic findings. Systemic amyloidosis is usually fatal, but the prognosis has improved as the result of increasingly effective treatments for many of the conditions that underlie it, notably the use of biologic anti-inflammatory agents in patients with AA amyloidosis and new immunomodulatory agents in patients with AL type. Better supportive care, including dialysis and solid organ transplantation, have also influenced the prognosis favourably. A range of specific novel therapies are currently in clinical development, including RNA inhibitors that suppress production of amyloid precursor proteins, drugs that promote their normal soluble conformation in the plasma, and immunotherapy approaches that directly target the amyloid deposits.

scholarly journals Interactional Imogen: language, practice and the body

2020 ◽  
Vol 19 (5) ◽  
pp. 933-960
Author(s):  
Harry Collins
Keyword(s):  
Artificial Intelligence ◽  
The Body ◽  
Human Group ◽  
Language Practice ◽  
Political Consequences ◽  
The Right ◽  
The Brain

Abstract Here I try to improve on the available answers to certain long-debated questions and set out some consequences for the answers. Are there limits to the extent to which we can understand the conceptual worlds of other human communities and of non-human creatures? How does this question relate to our ability to engage in other cultures’ practices and languages? What is meant by ‘the body’ and what is meant by ‘the brain’ and how do different meanings bear on the questions? The central answer developed here is that it is possible, given the right circumstances, for a competent human from any human group to understand the culture of any other human group without engaging in their practices though there are barriers when it comes to communication across species. This answer has important social and political consequences and consequences for the debate about artificial intelligence.

Convexity Meningioma Presenting as Postpartum Eclampsia

2003 ◽  
Vol 33 (1) ◽  
pp. 53-54 ◽  
Author(s):  
Bello B Shehu ◽  
Nasiru J Ismail
Keyword(s):  
Early Diagnosis ◽  
The Body ◽  
History Of ◽  
Neurological Features ◽  
The Right ◽  
The Brain ◽  
Tomography Scan ◽  
Progressive Weakness ◽  
In Pregnancy

A 37-year-old woman, Para 5+0 presented with a 1 year history of recurrent convulsions and progressive weakness of the right side of the body. She had been treated for postpartum eclampsia in her last delivery but symptoms recurred 3 months later. Evaluation including computerized tomography scan of the brain suggested a parieto-temporal meningioma, which was completely excised at craniotomy. Histology confirmed this to be a meningioma. The patient was well at 8 months of follow up. The growth of meningiomas may increase during pregnancy due to presence of receptors for progestational hormones in the tumour and the meningioma may become symptomatic in pregnancy, presenting as eclampsia. Close follow up of patients with eclampsia is necessary to identify neurological features that may lead to a diagnosis of meningioma. Early diagnosis is essential if a good outcome is to be ensured.

The physiology and pathophysiology of the neural control of the counterregulatory response

2012 ◽  
Vol 302 (2) ◽  
pp. R215-R223 ◽  
Author(s):  
Craig Beall ◽  
Michael L. Ashford ◽  
Rory J. McCrimmon
Keyword(s):  
Neural Control ◽  
Cell Function ◽  
Severe Hypoglycemia ◽  
Glucose Sensing ◽  
The Body ◽  
Increased Risk ◽  
Β Cell Function ◽  
The Neural Networks ◽  
The Brain

Despite significant technological and pharmacological advancements, insulin replacement therapy fails to adequately replicate β-cell function, and so glucose control in type 1 diabetes mellitus (T1D) is frequently erratic, leading to periods of hypoglycemia. Moreover, the counterregulatory response (CRR) to falling blood glucose is impaired in diabetes, leading to an increased risk of severe hypoglycemia. It is now clear that the brain plays a significant role in the development of defective glucose counterregulation and impaired hypoglycemia awareness in diabetes. In this review, the basic intracellular glucose-sensing mechanisms are discussed, as well as the neural networks that respond to and coordinate the body's response to a hypoglycemic challenge. Subsequently, we discuss how the body responds to repeated hypoglycemia and how these adaptations may explain, at least in part, the development of impaired glucose counterregulation in diabetes.

scholarly journals A REVIEW ON COVID-19 PANDEMIC A GLOBAL THREAT-CURRENT STATUS AND CHALLENGES AND PREVENTIVE STRATEGIES

2021 ◽  
pp. 10-14
Author(s):  
SUNITHA SUKUMARAN ◽  
S. SATHIANARAYANAN
Keyword(s):  
Immune System ◽  
Side Effects ◽  
Current Treatment ◽  
The Body ◽  
Current Status ◽  
Plasma Therapy ◽  
Angiotensin Converting Enzyme 2 ◽  
Life Threatening ◽  
Health Organization ◽  
Global Threat

Covid19 (Coronavirus) is a life-threatening virus that mainly affects our respiratory system, kidney, and GIT tract. People with a low immune system in their body fall prey to it. This virus (2019-nCoV) spreads easily from one person to another. As there is no treatment to kill the virus, the only way to stop this pandemic is through precautions and reduce the viral load in the body. This review reveals the main types of coronaviruses, history, pathophysiology, current treatment, drawbacks of current treatment, targets for drug development against Covid-19, vaccines discovered for covid-19, side effects of the currently available vaccines, and current status of this situation. The main mechanism of action of the virus easily enters to bind with the Angiotensin-Converting Enzyme 2 (ACE2) in the human body cells. Management of the virus several approaches will be taken mainly isolation of the patients and contacts the contacts, oxygen therapy for respiratory failure patients based on the severity Remdesivir, Lopinavir/ritonavir, Chloroquine, and Hydroxychloroquine, Alpha-interferon and plasma therapy can be used to control the infections. In India, AYUSH is also recommended to enhance the immune system through herbal-based products, Vaccination is also recommended by most of the countries, but many side effects and drug-drug interactions were reported for the above treatments. So that in future a new way of approach should be developed by our health organization as soon as possible.

scholarly journals EEG Asymmetries in Depressive Female Adolescents with Different Kinds of Auto-Aggressive Behavior

Psychiatry ◽  
2020 ◽  
Vol 18 (3) ◽  
pp. 14-21
Author(s):  
E. V. Iznak ◽  
E. V. Damyanovich ◽  
N. S. Levchenko ◽  
I. V. Oleichik ◽  
A. F. Iznak
Keyword(s):  
Aggressive Behavior ◽  
Left Hemisphere ◽  
Right Hemisphere ◽  
Spectral Power ◽  
Quantitative Eeg ◽  
Female Adolescents ◽  
Self Injury ◽  
Increased Risk ◽  
The Right ◽  
The Brain

Background: non-suicidal self-injury (NSSI) in adolescence is a significant risk factor for suicide, and therefore, the search for neurobiological markers and predictors of risk for suicidal intentions and actions seems to be an urgent task. In particular, quantitative EEG parameters can be such predictors.Objective: to identify the features of EEG in female adolescents with endogenous depressive conditions, manifested only by NSSI without suicidal intentions, in comparison with the EEG of patients who had suicidal auto-aggressive behavior (SAB) in the structure of depression.Patients and methods: the study was conducted as a comparative clinical and neurophysiological. The study included 45 female patients aged 16–25 years with endogenous depressive conditions, divided into 2 subgroups: those who showed only NSSI (NSSI subgroup, 21 patients), or who had a history of SAB (SAB subgroup, 24 patients). Clinical-psychopathological, psychometric, neurophysiological and statistical methods were used.Results and its discussion: intergroup differences were revealed in relation to the ratio and hemispheric asymmetry of the EEG spectral power of narrow frequency sub-bands of the parietal-occipital alpha rhythm. In the SAB subgroup alpha-2 (9–11 Hz) rhythm spectral power is higher than in the NSSI subgroup, the focus of alpha-2 spectral power is located in the right hemisphere, and alpha-3 sub-band (11–13 Hz) spectral power is higher than of alpha-1 (8–9 Hz). In the NSSI subgroup, alpha-1 (8–9 Hz) sub-band spectral power are higher than of alpha-3 (11–13 Hz), and focuses of alpha-2 (9–11 Hz) and alpha-3 (11–13 Hz) rhythms are localized in the left hemisphere. The results are discussed in terms of functional specialization of the brain hemispheres in relation to the regulation of emotions and control of behavior.Conclusions: the spatial distribution of the EEG frequency components in the SAB subgroup reflects the greater activation of the brain left hemisphere that is more typical for the EEG of individuals with an increased risk of suicide. In the NSSI subgroup, the right hemisphere is relatively more activated that is more typical for EEG in depressive disorders.The results obtained allow the use of quantitative EEG data to clarify the degree of suicidal risk in depressed female adolescents with non-suicidal self-injury.

scholarly journals HEALTH MEET - MUSIC

2015 ◽  
Vol 3 (1SE) ◽  
pp. 1-2
Author(s):  
Monisha Veeravani
Keyword(s):  
Music Therapy ◽  
Human Life ◽  
High Stress ◽  
The Body ◽  
Special Importance ◽  
Entire Body ◽  
Sound Waves ◽  
The Right ◽  
The Mind ◽  
The Brain

Music gives people a deeper understanding on the level of sensation and motivates them to become better and this element can change the world when it is wider than our own. It is music that connects the beginning to the end and becomes the literature of our heart. Fills the soul with affection, takes the mind from deep darkness to eternal heights. Music has the status of a® God, so purity has special importance in this genre. Music is the way to cultivate the mind through the seven pure and five vocal cords. Therefore, it can be said that music is necessary to keep the body and mind healthy, cheerful. This keeps the body, mind and brain healthy, and concentrates. Stress is also removed from music. It has been proved by various scientific experiments that both music practice and yoga practice develop strength in human life and many diseases can be treated. Music therapy i.e. music therapy nowadays plays an important role in relieving many health problems. Is playing If you live under high stress or are suffering from insomnia problem, then you can take help of this therapy. Each sound produces specific waves. These sound waves directly affect our brain. Everything in existence is affected by these waves. If a music is composed with the right words and the appropriate ragas, it will work on our brain in the same way that the software works inside a computer. Since our entire body is under the control of the brain, we can get the right result by having the expected effect on the brain through remedial music. संगीत लोगों को संवेदना के स्तर पर एक गहरी समझ देकर उन्हें बेहतर बनने की दिशा में प्रेरित करता है और यही तत्व जब निज से व्यापक होता है तो दुनिया भी बदल सकती है. ये संगीत ही है जो आदि को अंत से जोडकर हमारे हृदय का साहित्य बन जाता है। आत्मा को स्नेह से भर देता है मन को गहन अन्धकार से लेकर अनन्त ऊंचाइयों तक ले जाता है । संगीत क® ईश्वर का दर्जा प्राप्त है, इसीलिए इस विधा में शुध्दता का विशेष महत्व है। सात षुघ्द अ©र पांच क®मल स्वर®ं के माध्यम से मन क® साधने का उपाय है संगीत। अतः कहा जा सकता है कि शरीर तथा मन क® स्वस्थ््ा, प्रफुल्लित रखने के लिए संगीत आवश््यक है। इससे शरीर, मन, मस्तिष्क स्वस्थ््ा रहता है, एकाग्र रहता है। संगीत से तनाव भी दूर ह®ता है। विभिन्न वैज्ञानिक प्रयोगों द्वारा यह सिद्ध हो चुका है कि संगीत साधना व योग साधना दोनों से मनुष्य के जीवन में शक्ति का विकास होता है और अनेक बीमारियों का उपचार किया जा सकता है म्यूजिक थेरेपी यानी संगीत चिकित्सा आजकल अनेक स्वास्थ्य समस्याओं से राहत दिलाने में अहम भूमिका निभा रही है। आप अगर ज्यादा तनाव में रहते हैं या अनिद्रा की समस्या से पीडित हैं तो इस चिकित्सा की सहायता ले सकते हैं । हर ध्वनि से विशिष्ट तरंगें पैदा होती हैं। ये ध्वनि तरंगें सीधे हमारे मस्तिष्क को प्रभावित करती हैं। इन्हीं तरंगों से अस्तित्व में मौजूद हर चीज प्रभावित होती है। अगर कोई संगीत सही शब्दों और उपयुक्त रागों के साथ तैयार किया जाए तो वह हमारे मस्तिष्क पर उसी तरह काम करेगा जैसे किसी ’कम्प्यूटर’ के अंदर ’साफ्टवेयर’ काम करता है। चूंकि हमारा पूरा शरीर मस्तिष्क के नियंत्रण में होता है, इसलिए हम मस्तिष्क पर उपचारी संगीत के माध्यम से अपेक्षित प्रभाव डालकर सही परिणाम प्राप्त कर सकते हैं।

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