Effect of micro-osteoperforation on the rate of orthodontic tooth movement—a systematic review and a meta-analysis

2019 ◽  
Vol 42 (2) ◽  
pp. 211-221 ◽  
Author(s):  
Mostafa Shahabee ◽  
Hooman Shafaee ◽  
Mostafa Abtahi ◽  
Abdolrasoul Rangrazi ◽  
Erfan Bardideh
Keyword(s):  
Systematic Review ◽  
Adverse Effects ◽  
Orthodontic Treatment ◽  
Randomized Clinical Trials ◽  
Tooth Movement ◽  
Root Resorption ◽  
Meta Analysis ◽  
Orthodontic Tooth Movement ◽  
Mean Difference ◽  
Canine Retraction

Abstract Background The micro-osteoperforation can be used to increase the rate of tooth movement, simplify complex orthodontic movements, and also help adjust the anchorage but there are conflicting reports on the effectiveness and adverse effects of this intervention. Objectives The aim of our systematic review and meta-analysis was to evaluate the effects of micro-osteoperforation on the rate of tooth movement in patients undergoing orthodontic treatment. Search methods A comprehensive search of MEDLINE, ISI web of science, EMBASE, Scopus, and CENTRAL online databases for studies measuring the effects of micro-osteoperforation on the rate of orthodontic tooth movement from inception to February 2019 was performed. Selection criteria Based on the PICO model, human studies which evaluated the effects of MOP on the rate of tooth movement in patients undergoing orthodontic treatment were selected for this review. Data collection and analysis The relevant data from the eligible studies were extracted using piloted custom extraction forms. The data were combined and analysed using inverse-variance random-effect meta-analysis and the mean difference was used for comparing the outcome measures. Results Six randomized clinical trials were finally included in this meta-analysis. The rate of canine retraction per month was significantly higher in the MOP group [mean difference (MD) = 0.45 mm, 95% CI = 0.17–0.74]. These results were similar with regard to different malocclusions, the jaw on which it was performed, and MOP methods. The patients did not report any significant differences in terms of pain severity levels after MOP. With regard to the adverse effects, one study reported higher amounts of root resorption among patients undergoing MOP. Conclusions The rate of tooth movement was increased after performing MOP but in at least one study higher root resorption was observed. Therefore, the use of MOP can be recommended after weighing the benefits and disadvantages this intervention can bring for each patient. Registration The protocol for this review was registered via crd.york.ac.uk/prospero with the ID CRD42019115499.

scholarly journals Low-level Laser Therapy in the Acceleration of Fixed Orthodontic Tooth Movement: Protocol for a Systematic Review and Network Meta-analysis

2021 ◽  
Author(s):  
Ziyuan Guo ◽  
Lijuan Zhou ◽  
Chong Feng ◽  
Xiao Chang ◽  
Kaifang Han ◽  
...  
Keyword(s):  
Systematic Review ◽  
Adverse Effects ◽  
Laser Therapy ◽  
Orthodontic Treatment ◽  
Tooth Movement ◽  
Meta Analysis ◽  
Orthodontic Tooth Movement ◽  
Low Level Laser Therapy ◽  
Level Laser ◽  
Meta Analyses

Abstract Background: Orthodontic treatment is a long-term therapy with time-related adverse effects. Low-level laser therapy (LLLT) has been used in the clinic as an intervention to accelerate orthodontic tooth movement (OTM) and prevent adverse effects. Previous systematic reviews have evaluated the effectiveness of LLLT in the acceleration of OTM. However, it remains unclear which treatment parameters are appropriate for LLLT. This review will evaluate the efficacy of LLLT on the acceleration of fixed OTM and the prevention of adverse effects.Methods: Several electronic databases will be searched. Grey literature also will be retrieved. Parallel or clustered randomised controlled trials that evaluated the effectiveness of different LLLTs on the acceleration of fixed OTM will be included. Two researchers will independently screen all titles, abstracts, and full-text articles retrieval, as well as data extraction. The risk bias of each study will be appraised using the Cochrane Risk of Bias tool (RoB 2.0). The primary outcome will be the efficacy of LLLT on the acceleration of fixed OTM (e.g., canine movement distance, orthodontic treatment duration). Secondary outcomes will be the effectiveness of LLLT to reduce orthodontic adverse effects such as pain and root resorption. The mean difference (MD) and relative risk (RR) with corresponding 95% confidence intervals (CI) will be chosen as effective measures for continuous and binary outcomes, respectively. When feasible, both fixed and random-effects pairwise meta-analyses and frequentist network meta-analyses will be conducted.Discussion: This network meta-analysis will compare the efficacy of LLLT on the acceleration of fixed OTM as well as whether LLLT can prevent adverse effects of this orthodontic treatment. By integrating the current evidence from direct and indirect comparisons and ranking all included interventions, our findings have the potential to help clinicians achieve more effective treatment goals.Systematic review registration: PROSPERO CRD42020175850

scholarly journals Comparison of rate of maxillary canine movement with or without modified corticotomy facilitated orthodontic treatment: A prospective clinical trial

2015 ◽  
Vol 5 ◽  
pp. 138-143 ◽  
Author(s):  
Harshal N. Suryavanshi ◽  
Vaishali R. Das ◽  
Aashish Deshmukh ◽  
Raj Rai ◽  
Mena Vora
Keyword(s):  
Orthodontic Treatment ◽  
Tooth Movement ◽  
Root Resorption ◽  
Treatment Time ◽  
Orthodontic Tooth Movement ◽  
Radiographic Examination ◽  
Maxillary Canine ◽  
Mean Velocity ◽  
Canine Retraction ◽  
Extraction Therapy

Background and Objectives The average orthodontic treatment time for extraction therapy is 31 months. One of the main disadvantages of orthodontic treatment is time. Alveolar corticotomies have been used in conjunction with orthodontics to reduce the treatment time by increasing the rate of tooth movement. Concerns about the possible risks of corticotomy procedure have led to the modification of this technique. Germeç et al. reported a case treated by their modified corticotomy technique and noted reduced treatment time without any adverse effects on the periodontium and the vitality of teeth with their new conservative corticotomy technique. This study was undertaken to clinically evaluate the efficacy of the aforesaid technique. Materials and Methods A split-mouth study design was carried out to compare the rate of maxillary canine movement with and without modified corticotomy facilitated orthodontic treatment in 10 patients requiring maxillary first premolar extractions. The modified corticotomy procedure was performed on the maxillary arch unilaterally. The upper arch was immediately activated bilaterally after surgical procedure using equal orthodontic forces for retraction of the maxillary canines. The amount of tooth movement was recorded at an interval of every month till the completion of canine retraction. The rate of canine movement on experimental and control site was compared. The patients were followed for 6 months to check the occurrence of undesired effects such as root resorption, periodontal damage and loss of vitality of teeth on the experimental side. Results Higher mean velocity was observed in canines with modified corticotomy facilitated retraction compared to conventionally retracted canines; with the difference in mean velocity between the two groups was found to be clinically significant as well as statistically significant (P < 0.001). Interpretation and Conclusion The results suggested that modified corticotomy technique serves as an effective and safe way to accelerate orthodontic tooth movement, without adversely affecting the periodontium, root resorption, and the vitality of the teeth, as concluded by clinical and radiographic examination.

scholarly journals Are Mechanical Vibrations an Effective Alternative to Accelerate Orthodontic Tooth Movement in Humans? A Systematic Review

2021 ◽  
Vol 11 (22) ◽  
pp. 10699
Author(s):  
María Fernanda García Vega ◽  
Laura Mónica López Pérez-Franco ◽  
Alejandro Dib Kanán ◽  
Cristian Dionisio Román Méndez ◽  
Jesús Eduardo Soto Sainz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Clinical Trials ◽  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Low Frequency ◽  
Mechanical Vibrations ◽  
Eligibility Criteria ◽  
Canine Retraction ◽  
Randomized Controlled ◽  
Bias Risk

The objective of this article was to conduct a systematic review of the literature to contrast the existing evidence on the effect of mechanical vibrations, either high or low frequency, as an alternative to accelerate orthodontic tooth movement in humans. A literature search from 2010 to June 2021 was conducted in the electronic databases: PubMed, NCBI, Google Scholar, EBSCO, Cochrane, and Ovid, using the eligibility criteria to identify the studies. Only randomized clinical trials (RCT) were included. The certainty of the evidence was assessed using the GRADE tool and the risk of bias (RoB) in individual studies was evaluated according to the Cochrane bias risk tool. Fifteen RTCs were included for final review. Overall, the RoB was classified as low (3), moderate (5), and high (7). Three articles with low RoB, four with moderate RoB, and four with high RoB found no significant effect in the use of vibrations on orthodontic movement. Only four articles, three of them with high RoB and one with moderate RoB, found that mechanical vibrations are effective at accelerating orthodontic tooth movement. The results seemed to indicate that there is no evidence that vibratory stimuli can increase the rate of dental movement or reduce neither the time of dental alignment nor canine retraction during orthodontic treatment. It is important to note that a greater number of high-quality randomized controlled trials are urgently needed.

Effectiveness and Safety of Minimally Invasive Orthodontic Tooth Movement Acceleration: A Systematic Review and Meta-analysis

2019 ◽  
Vol 98 (13) ◽  
pp. 1469-1479 ◽  
Author(s):  
T. Fu ◽  
S. Liu ◽  
H. Zhao ◽  
M. Cao ◽  
R. Zhang
Keyword(s):  
Systematic Review ◽  
Minimally Invasive Surgery ◽  
Adverse Effects ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Tooth Movement ◽  
Treatment Time ◽  
Meta Analysis ◽  
Orthodontic Tooth Movement ◽  
Sufficient Evidence

Doctors and patients attempt to accelerate orthodontic tooth movement with a minimally invasive surgery approach. The purpose of this systematic review was to evaluate the evidence of accelerated tooth movement in minimally invasive surgery and the adverse effects from it. A systematic search of the literature was performed in the electronic databases of PubMed, CENTRAL (Cochrane Central Register of Controlled Trials), Embase, Scopus, Web of Science, Science Direct, and Medline and was complemented by a manual search until February 2019. The inclusion criteria were prospective clinical studies of patients treated with a fixed appliance, and the intervention was accelerated orthodontic treatment with minimally invasive surgery. Nineteen articles (538 participants) were included in the review: 9 studies assessed the rate of upper canine movement; 5 considered the treatment time; 1 evaluated the en masse retraction time; and 4 studied adverse effects. We performed a meta-analysis for the rate of canine movement and treatment time and described the results for the adverse effects in a systematic review. The results of the subgroup analysis according to micro-osteoperforation and piezocision were included in the study. No accelerated tooth movement was found in the micro-osteoperforation group. After flapless corticotomy procedures, increased tooth movement rates were identified by weighted mean differences of 0.63 (95%CI = 0.22, 1.03, P = 0.003) and 0.64 (95% CI, −25 to 1.53; P = 0.16) for 1 and 2 mo, respectively. The mean treatment time was 68.42 d (95% CI, −113.19 to −23.65; P = 0.003) less that than for minimally invasive surgery. Moreover, no significant adverse effect was found. Because of the high heterogeneity of the meta-analysis, the results must be validated by additional large-sample multicenter clinical trials. There is not sufficient evidence to support that the single use of micro-osteoperforation could accelerate tooth movement, and there is only low-quality evidence to prove that flapless corticotomy could accelerate tooth movement.

scholarly journals Is Inflammation a Friend or Foe for Orthodontic Treatment?: Inflammation in Orthodontically Induced Inflammatory Root Resorption and Accelerating Tooth Movement

2021 ◽  
Vol 22 (5) ◽  
pp. 2388
Author(s):  
Masaru Yamaguchi ◽  
Shinichi Fukasawa
Keyword(s):  
Inflammatory Mediators ◽  
Orthodontic Treatment ◽  
Alveolar Bone ◽  
Tooth Movement ◽  
Root Resorption ◽  
Orthodontic Tooth Movement ◽  
Tnf Α ◽  
Orthodontic Forces ◽  
Necrosis Factor

The aim of this paper is to provide a review on the role of inflammation in orthodontically induced inflammatory root resorption (OIIRR) and accelerating orthodontic tooth movement (AOTM) in orthodontic treatment. Orthodontic tooth movement (OTM) is stimulated by remodeling of the periodontal ligament (PDL) and alveolar bone. These remodeling activities and tooth displacement are involved in the occurrence of an inflammatory process in the periodontium, in response to orthodontic forces. Inflammatory mediators such as prostaglandins (PGs), interleukins (Ils; IL-1, -6, -17), the tumor necrosis factor (TNF)-α superfamily, and receptor activator of nuclear factor (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) are increased in the PDL during OTM. OIIRR is one of the accidental symptoms, and inflammatory mediators have been detected in resorbed roots, PDL, and alveolar bone exposed to heavy orthodontic force. Therefore, these inflammatory mediators are involved with the occurrence of OIIRR during orthodontic tooth movement. On the contrary, regional accelerating phenomenon (RAP) occurs after fractures and surgery such as osteotomies or bone grafting, and bone healing is accelerated by increasing osteoclasts and osteoblasts. Recently, tooth movement after surgical procedures such as corticotomy, corticision, piezocision, and micro-osteoperforation might be accelerated by RAP, which increases the bone metabolism. Therefore, inflammation may be involved in accelerated OTM (AOTM). The knowledge of inflammation during orthodontic treatment could be used in preventing OIIRR and AOTM.

scholarly journals Root Resorption in Orthodontic Treatment: Scoping Review

2018 ◽  
Vol 7 (2) ◽  
pp. 47-51
Author(s):  
Neeta Aryal ◽  
Mao Jing
Keyword(s):  
Scoping Review ◽  
Orthodontic Treatment ◽  
Tooth Movement ◽  
Root Resorption ◽  
Orthodontic Tooth Movement ◽  
Conventional Radiography ◽  
Promising Tool ◽  
External Root Resorption ◽  
Long Time ◽  
Orthodontic Patients

Introduction: Root resorption is the loss of apical root tissue leading to the shortness of root which is often evident in orthodontic tooth movement. Proper management during orthodontic treatment however can minimize this undesirable outcome. The present article attempts to review the etiology of root resorption, methods of diagnosis, and strategies for prevention.Materials & Method: A scoping review was done with the purpose to carry out the narrative integration of the relevant evidences on root resorption and orthodontic treatment from the published literatures. The resulting papers were studied and reviewed thoroughly for the key explanation of root resorption in orthodontic patients. A total of 41 published research articles were reviewed.Discussion: According to the literatures root resorption is common iatrogenic outcome in orthodontic treatment. Biological, mechanical, and combined biological and mechanical factors result in external root resorption. Though most clinicians diagnose root resorption by conventional radiography, researches have clearly shown that CBCT is the promising tool. The clinicians need to counsel orthodontic patients and their parents that the root resorption might be a potential consequence of the treatment lasting for long time. In case of severity; it is essential to reassess the patient and minimize the underlying cause. It is necessary to understand the role of orthodontist in preventing root resorption

scholarly journals The Effects of Modified Simiao Decoction in the Treatment of Gouty Arthritis: A Systematic Review and Meta-Analysis

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Ya-Fei Liu ◽  
Ying Huang ◽  
Cai-Yu-Zhu Wen ◽  
Jun-Jun Zhang ◽  
Guo-Lan Xing ◽  
...  
Keyword(s):  
Systematic Review ◽  
Uric Acid ◽  
Adverse Effects ◽  
Randomised Controlled Trials ◽  
Meta Analysis ◽  
Gouty Arthritis ◽  
Mean Difference ◽  
Controlled Trials ◽  
Randomised Controlled ◽  
Anti Inflammation

The modified Simiao decoctions (MSD) have been wildly applied in the treatment of gouty arthritis in China. However, the evidence needs to be evaluated by a systematic review and meta-analysis. After filtering, twenty-four randomised, controlled trials (RCTs) comparing the effects of MSD and anti-inflammation medications and/or urate-lowering therapies in patients with gouty arthritis were included. In comparison with anti-inflammation medications, urate-lowering therapies, or coadministration of anti-inflammation medications and urate-lowering therapies, MSD monotherapy significantly lowered serum uric acid (p<0.00001, mean difference = −90.62, and 95% CI [−128.38, −52.86];p<0.00001, mean difference = −91.43, and 95% CI [−122.38, −60.49];p=0.02, mean difference = −40.30, and 95% CI [−74.24, −6.36], resp.). Compared with anti-inflammation medications and/or urate-lowering therapies, MSD monotherapy significantly decreased ESR (p<0.00001; mean difference = −8.11; 95% CI [−12.53, −3.69]) and CRP (p=0.03; mean difference = −3.21; 95% CI [−6.07, −0.36]). Additionally, the adverse effects (AEs) of MSD were fewer (p<0.00001; OR = 0.08; 95% CI [0.05, 0.16]). MSD are effective in the treatment of gouty arthritis through anti-inflammation and lowering urate. However, the efficacy of MSD should be estimated with more RCTs.

scholarly journals Comparison of InvisalignⓇ Aligners versus Fixed Appliance Treatment in pain perception: a systematic review and meta-analysis

2019 ◽  
Author(s):  
Dinis Pereira ◽  
Vanessa Machado ◽  
João Botelho ◽  
José João Mendes ◽  
Ana Sintra Delgado
Keyword(s):  
Systematic Review ◽  
Random Effects ◽  
Orthodontic Treatment ◽  
Pain Perception ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Multiple Time ◽  
Case Control Studies ◽  
Standard Material ◽  
Fixed Appliances

Abstract Background: This systematic review aimed to compare the pain discomfort levels between InvisalignⓇ aligners comparing with traditional fixed appliances at multiple time points, through Pain Visual Analog Scale (VAS). Methods: Four electronic databases (Pubmed, Medline, CENTRAL and Scholar) were searched up to February 2019. There were no restrictions on year and publication status. Randomized clinical trials (RCTs) and case-control studies comparing pain perception through VAS in patients treated with Invisalign aligners and with labial appliances were included. Risk of bias within and across studies was assessed using Cochrane tool and Newcastle-Ottawa Scale (NOS) approach. Random-effects meta-analysis were conducted. VAS score at 1, 3 and 7 days, and analgesic consumption was collected. Pairwise and Binary Random-Effects Meta-analyses were used to synthesize available data. Results: At the initial search, a total of 87 articles were retrieved. Following the review protocol, 4 articles met the inclusion criteria and were included, with a total of 214 participants (139 females, 75 males). All studies were considered of high methodological quality. The results demonstrate that Invisalign aligners seems to be associated with significantly less pain than fixed appliances at 7 days after beginning the orthodontic treatment, although at 1 and 3 days the pain experience was similar in both orthodontics appliances. In regard to the type of material, SmartTrackⓇ aligners appear to give significantly better comfort for orthodontic patients than previous standard material, being that 3 days after appliance’s insertion this pain differential becomes significant, and this difference is more pronounced at 7 days. Conclusion: Patients treated with Invisalign experience less pain discomfort than those treated with fixed appliances and consume less analgesics. Overall, Invisalign promotes better pain and discomfort experience for the patient in the course of orthodontic treatment. Larger RCTs are needed to definitely demonstrate these findings throughout the orthodontic treatment.

scholarly journals Surveillance in inflammatory bowel disease: is chromoendoscopy the only way to go? A systematic review and meta-analysis of randomized clinical trials

2020 ◽  
Vol 08 (05) ◽  
pp. E578-E590
Author(s):  
Ricardo Hannum Resende ◽  
Igor Braga Ribeiro ◽  
Diogo Turiani Hourneaux de Moura ◽  
Facundo Galetti ◽  
Rodrigo Silva de Paula Rocha ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Meta Analysis ◽  
Mean Difference ◽  
Procedure Time ◽  
High Definition ◽  
Number Of Patients

Abstract Background and study aims Ulcerative colitis (UC) and Crohn’s disease (CD) have higher risk of colorectal cancer (CRC). Guidelines recommend dysplasia surveillance with dye-spraying chromoendoscopy (DCE). The aim of this systematic review and meta-analysis was to review all randomized clinical trials (RCTs) available and compare the efficacy of different endoscopic methods of surveillance for dysplasia in patients with UC and CD. Methods Databases searched were Medline, EMBASE, Cochrane and SCIELO/LILACS. It was estimated the risk difference (RD) for dichotomous outcomes (number of patients diagnosed with one or more dysplastic lesions, total number of dysplastic lesions diagnosed and number of dysplastic lesions detected by targeted biopsies) and mean difference for continuous outcomes (procedure time). Results This study included 17 RCTs totaling 2,457 patients. There was superiority of DCE when compared to standard-definiton white light endoscopy (SD-WLE). When compared with high-definition (HD) WLE, no difference was observed in all outcomes (number of patients with dysplasia (RD 0.06; 95 % CI [–0.01, 0.13])). Comparing other techniques, no difference was observed between DCE and virtual chromoendoscopy (VCE – including narrow-band imaging [NBI], i-SCAN and flexible spectral imaging color enhancement), in all outcomes except procedure time (mean difference, 6.33 min; 95 % CI, 1.29, 11.33). DCE required a significantly longer procedure time compared with WLE (mean difference, 7.81 min; 95 % CI, 2.76, 12.86). Conclusions We found that dye-spraying chromoendoscopy detected more patients and dysplastic lesions than SD-WLE. Although no difference was observed between DCE and HD-WLE or narrow-band imaging, the main outcomes favored numerically dye-spraying chromoendoscopy, except procedure time. Regarding i-SCAN, FICE and auto-fluorescence imaging, there is still not enough evidence to support or not their recommendation.

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