scholarly journals 149 Myocardial performance in opera singers

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Laura Stefani ◽  
Marco Corsi ◽  
Goffredo Orlandi

Abstract Aims Opera singers are subjected to continuous exercise in the cardiopulmonary district, however the impact on cardiac performance has not been studied in depth. In addition to the standard echo parameters, the deformation one offer the possibility to evaluate more clearly the myocardial performance. Objective was to verify the impact of singing in heart’s performance by the evaluation of traditional and particularly deformation parameters as strain, rotation, and twist. Methods and results A population of 17 OS (opera singers, aged 50 ± 5 years) (M/F: 7/9; 5 sopranos; 2 tenors; 2 contraltos; 2 basses) have been submitted to an echocardiographic evaluation (MLX8exp Release F100001) by standard 2D and deformation parameters (Figure 1). The data expressed as mean as SD were compared to an high level athletes (A) group (M 16) regularly trained. T-Student test for paired data was used and P < 0.05 was considered significant. All the 2D standard systo-diastolic parameters were within the normal range and the pulmonary pressure (PP) as well in both. In SO group were: LVDd: 47.31 ± 3.77 mm; LVSd: 30.48 ± 4.42 mm; E/A: 1.07 ± 0.32; RV: 27.63 ± 4.50 mm; in A group: LVDd: 50.81 ± 2.97 mm; LVSd: 31.44 ± 4.26 mm; E/A: 2.68 ± 1.67; RV: 27.63 ± 4.50 mm. As expected Cardiac mass index (CMI) was significantly greater in athletes, while the ejection fraction (EF) resulted to be higher in OS. Despite the deformation parameters were not different among the two groups, with the exclusion of GLS expressing a major value in athletes, on the contrary the rotational parameters resulted, in OS group similar to the athletes and in agreement with an high performance status. Conclusions OS show an high myocardial performance as athletes. The data obtained are suggestive for a positive impact of regular training as an opera singers. Deformation parameters highlight the fitness status in this particular group. Classic music singing seems to have a training effect on the heart. Further studies will be necessary to confirm this hypothesis

2020 ◽  
Vol 10 (3) ◽  
pp. 228-236 ◽  
Author(s):  
Lamia Taouzinet ◽  
Sofiane Fatmi ◽  
Allaeddine Khellouf ◽  
Mohamed Skiba ◽  
Mokrane Iguer-ouada

Background: Alpha-tocopherol is a potent antioxidant involved in sperm protection particularly during cryopreservation. However, its poor solubility limits the optimal protection in aqueous solutions. Objective: The aim of this study was to enhance the solubility of α-tocopherol by the use of liposomes. Methods: The experimental approach consisted to load vitamin E in liposomes prepared by ethanol injection method and the optimization carried out by an experimental design. The optimum solution was characterized by high performance liquid chromatography and scanning electron microscope. Finely, the impact on sperm motility protection was studied by the freezing technic of bovine sperm. Results: The optimum solution was obtained when using 10.9 mg/ml of phospholipids, 1.7 mg/ml of cholesterol and 2 mg/ml of vitamin E. The liposome size was 99.86 nm, providing 78.47% of loaded efficiency. The results showed also a significant positive impact on sperm motility after hours of preservation. Conclusion: In conclusion, the current results showed the interest of liposome preparation as an alternative to enhance vitamin E solubility and to protect spermatozoa during cryopreservation.


2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii186-ii186
Author(s):  
O’Dell Patrick ◽  
H Nickols ◽  
R LaRocca ◽  
K Sinicrope ◽  
D Sun ◽  
...  

Abstract BACKGROUND Patients who have recurrent glioblastoma have limited treatment options. We conducted a retrospective review of patients with recurrent glioblastoma treated with standard initial radiation and temozolomide with tumor treating fields to investigate whether reirradiation using radiosurgery would be associated with improved outcomes. METHODS We reviewed the records of 54 consecutively treated patients with recurrent glioblastoma with ECOG 0 or 1 at recurrence and conducted Kaplan-Meier analysis with Log-rank testing to determine significance between groups. RESULTS We identified 24 patients who were treated without radiation therapy (control) while 30 patients underwent re-irradiation using radiosurgery (ReSRS) with a median total dose of 25Gy in five fractions. All patients had completed standard initial therapy, and there was no difference in the time to recurrence between the two groups (10 months for control, 15 months for ReSRS, [P = 0.17, HR for progression 0.65 (95% CI 0.38-1.13)]. A larger proportion of patients in the control arm (54%) had subtotal or gross total resection of the recurrence compared with the ReSRS group (44%, P < 0.05). The majority of patients had recurrence confirmed with biopsy (18/22 in control group, 25/31 in the ReSRS group). MGMT methylation status did not differ between control vs ReSRS (29% vs. 27%). ReSRS was associated with improved median survival from the time of first recurrence of 11.6 months versus 3.8 months in the control arm [P< 0.0001, HR for death 0.33 (95% CI 0.18-0.6)]. CONCLUSIONS In a group of patients with high performance status diagnosed with recurrent glioblastoma, reirradiation with stereotactic radiosurgery was associated with nearly one year median survival after recurrence. Additional analyses are warranted to determine the impact of concurrent systemic therapies with irradiation and underlying tumor or patient factors to predict outcomes.


2020 ◽  
Vol 12 (5) ◽  
pp. 1866 ◽  
Author(s):  
Fen Zhang ◽  
Xiaonan Qin ◽  
Lina Liu

Few studies have been conducted on whether the coexistence of green innovation and corporate social responsibility (CSR) has a favorable interaction effect on firm value. This interaction effect is of great significance for enterprises balancing resource allocation between two factors in the future. Meanwhile, information disclosure can reflect the efforts of enterprises in taking on CSR. Therefore, taking China’s listed companies as an example, this paper studies the interaction effect of CSR after being divided into the three different dimensions of environment, society, and governance (ESG) and green innovation on firm value. The quantile regression method can reflect the impact of CSR and green innovation on the firm value of different levels. The study finds that: (1) green innovation can promote the improvement of medium- and high-level firm value; (2) only the disclosure of environmental and social information can have a positive impact on firm value; (3) the interaction effect between green innovation and social disclosure on firm value is a substitution effect, which will gradually weaken with the increase of firm value. This paper proposes that relevant departments should guide green funds into enterprises with capital constraints to alleviate the issue of fund crowding into CSR and green innovation.


2020 ◽  
Vol 9 (6) ◽  
pp. 1960
Author(s):  
Maria Isabel Carrasco-Zafra ◽  
Rafael Gómez-García ◽  
Ricardo Ocaña-Riola ◽  
Maria Luisa Martín-Roselló ◽  
Encarnación Blanco-Reina

The current treatment approach for patients in palliative care (PC) requires a health model based on shared and individualised care, according to the degree of complexity encountered. The aims of this study were to describe the levels of complexity that may be present, to determine their most prevalent elements and to identify factors that may be related to palliative complexity in advanced-stage cancer patients. An observational retrospective study was performed of patients attended to at the Cudeca Hospice. Socio-demographic and clinical data were compiled, together with information on the patients’ functional and performance status (according to the Palliative Performance Scale (PPS)). The level of complexity was determined by the Diagnostic Instrument of Complexity in Palliative Care (IDC-Pal©) and classified as highly complex, complex or non-complex. The impact of the independent variables on PC complexity was assessed by multinomial logistic regression analysis. Of the 501 patients studied, 44.8% presented a situation classed as highly complex and another 44% were considered complex. The highly complex items most frequently observed were the absence or insufficiency of family support and/or caregivers (24.3%) and the presence of difficult-to-control symptoms (17.3%). The complex item most frequently observed was an abrupt change in the level of functional autonomy (47.6%). The main factor related to the presence of high vs. non-complexity was that of performance status (odds ratio (OR) = 10.68, 95% confidence interval (CI) = 2.81–40.52, for PPS values < 40%). However, age was inversely related to high complexity. This study confirms the high level of complexity present in patients referred to a PC centre. Determining the factors related to this complexity could help physicians identify situations calling for timely referral for specialised PC, such as a low PPS score.


Author(s):  
Yurii Malakhovskyi ◽  
◽  
Oleh Onofriichuk ◽  
Olena Kulishova ◽  
◽  
...  

The purpose of this publication is to study the system of economic security parameters and improve the process of using RADAR logic as an element of assessing the information security of the enterprise. The importance of the concept of economic security of enterprises (EBP) is that scientists recognize it as an important factor in national security, since the real economy is an environment of planning, organization and the best use of resources. Four main factors of EBP are considered: a) planning; b) monitoring of the external and internal environment; (b) identifying and implementing threat response measures; d) control and improvement of the system. Taking into account the turbulence of the external environment, the impact on the formation of parameters of the EBP of macro-, meso- and microeconomic level factors is investigated. It is proposed to lay the methodology based on the model of the European Quality Management Fund (EFQM) as the basis for the formation of the EBP culture. Its goal is to achieve a high level of business excellence, the direction is to promote the processes of coordination of business and security goals, coordination of efforts to achieve sustainable security indicators, the formation of market knowledge and best practices for their exchange. The prospects for practical use of the EFQM model, the components of which are: basic concepts of perfection are carefully studied; criteria; RADAR logic. The conclusion about the feasibility of implementing the RADAR system is substantiated. Full and comprehensive implementation of the system can have a positive impact on the level of short-term liquidity of the company's assets, its long-term solvency, the formation of the desired level of profitability for shareholders, and generate positive external effects for society and the environment. The complexity of ensuring the EBP is explained by the variety of manifestations and relationships of interactive elements among the internal components of enterprises and the unpredictability of the manifestation of external factors. A logical conclusion is drawn about the importance of the EBP concept, its ability to include a significant number of factors in the sphere of management influence. The direct consequences of using the EBP concept are the comprehensive provision of both its own economic security and the fundamental principles of its organization, the safety of the activities of individuals, the ability to take into account numerous factors in the formation of the actual level of regional, national and international economic security of the state. The strategic directions of further research are outlined: study, schematization, numerical formalization of system-structural relations of components and threats to economic security of enterprises, the real sector and the national economy as a whole.


Author(s):  
Abeer Mokhtar Sewify

The current research aims to examine the impact of talent management on the organizational identification. The research was conducted in the Office of Innovation Support, Transfer and Marketing of Technology at Al-Azhar University. The importance of the research is derived from the need of investigated organization to apply effective talent management which maximize benefiting from talents. The research problem was represented in the following inquiry: Does talent management have an impact on organizational identification of members and coordinators of the Office of Innovation, Technology Transfer and Marketing (TAICO) at Al-Azhar University? The research attempted to test the validity of the following hypotheses: There is a high level of practicing talent management in the investigated organization, -There is a high level of practicing organizational identification in the investigated organization. -Talent management has a significant positive impact on organizational identification. The number of members and coordinators of the TAICO office reached 37 people, yet 32 of them were listed at 86%. The research relied on the Analytical descriptive method. Some statistical methods were used, including the Pearson correlation coefficient and the T-test, as well as the simple regression test to determine the correlation and impact relationships. Moreover, results showed that talent management obtained a low estimation with mean of 2.36, also, the mean of organizational identification was 2.40. Results indicated that there was a significant effect of talent management on organizational identification, as T value reached 9.628, which was significant at 0.01 level. The research recommended the necessity of adopting effective talent management strategies to discover talented people, observe their development and direct them in the right direction, and also conducting a periodic evaluation that shows the extent of the development of those talents and finding common values and goals between the members and the TAICO office, in a way that contributes to enhancing organizational identification.


2021 ◽  
Vol 13 (17) ◽  
pp. 9538
Author(s):  
Muhammad Waleed Ayub Ghouri ◽  
Linchen Tong ◽  
Muhammad Ali Hussain

Due to the phenomenal growth of e-commerce, online shopping has recently become a worldwide trend. This fosters many online shopping platforms to enter into Asian emerging markets, which evolves a need to understand online decision-making processes in this particular context. Addressing this gap, our study initialized an integrated framework based on Uses and Gratification theory and the Cognitive–Affect–Behavior paradigm to examine the impact of gratification elements on customer satisfaction and convenience enforcing continuance shopping intention. Moreover, we also conceptualize the moderating role of online ratings in our study. In total, 317 valid questionnaires from Pakistani online shoppers were incorporated to statistically test our model using the Structural Equation Modeling (SEM) approach in Amos. Besides, the results confirm the positive impact of layout and functionality on customer satisfaction and convenience, while the impact of PEEIM has been found insignificant. Furthermore, customer satisfaction and convenience are found to be the imperative predictors of continuance shopping intention. Our findings exhibit that a high level of online rating strengthens the direct effect of satisfaction and convenience on continuance intention. Theoretical and practical implications for future scholars and e-commerce shopping platforms are discussed.


2021 ◽  
Vol 67 (2) ◽  
pp. 69-75
Author(s):  
Vojislav Božanić ◽  
Vlastimir Dedovic ◽  
Milan Božović

The paper presents an overview of the most important regulations and institutions affecting the level of quality and fittingness of the vehicle fleet, in order to increase the level of general traffic safety in the Republic of Serbia. The Traffic Safety Agency, among other things, alone or in cooperation with others, regulates, controls and implements the system of homologation, testing and control of conformity of vehicles, equipment and parts. It authorizes and supervises other organizations for vehicle control and testing. The role of standardization in this process is dual: first - it refers to the subject of testing - vehicles, and second - to the quality of testing - authorized organizations. The paper discusses the important provisions of regulations for vehicle testing and analyzes the impact of the standards ISO 17020 and ISO 17025 on the work of authorized organizations. In conclusion, it was proposed that in order to achieve and maintain high level of testing quality, mandatory accreditation of authorized organizations should be prescribed. Mandatory application of the standards would have a positive impact on the traffic safety segment which depends on the technical characteristics of the vehicle, and as well, reduce the Agency's obligations.


Author(s):  
Nguyen Anh Phong ◽  
Bui Thi Quynh Dao ◽  
Le Thi Thuy Hue ◽  
Nguyen Ngoc Van Khanh ◽  
Nguyen Lam Thanh Ngan ◽  
...  

This research evaluates the impact of ICT on the technical efficiency of firms in 63 provinces and cities in Vietnam. We apply to use the DEA method in which we use the variable return to scale to evaluate because firm sizes in 63 provinces are different. At the same time, this method aims to minimize input factors without reducing output factors to measure technical efficiency. This result that is used a binary variable in the logit regression model to identify factors that have an impact on technical efficiency, especially the ICT factor. The research results show that only nearly 10% of the provinces could be technically efficient in business activities. Provinces with sustainable performance and efficiency all depend on influencing factors such as equity ratio, labor productivity, market size, investment, and especially the ICT factor keep increasing over the years and fluctuate around a pretty high level. On the other hand, for the group of unsustainable and ineffective provinces, these variables tend to decrease and fluctuate around at a low level. The research shows that factors in labor productivity, equity ratio, market size, investment, and ICT all have a positive impact on a firm’s performance in 63 provinces and cities of Vietnam. Therefore, firms that want to enhance their efficiency need to have strategies to improve the factors mentioned above. Moreover, the local government needs to improve the ICT index to help to increase their local Enterprises’ efficiency.


2019 ◽  
pp. 265-271 ◽  
Author(s):  
Ibrahim Rached Al Taweel

This paper summarizes the arguments and counterarguments within the scientific discussion on the issue the link between organizational cultures on the job performance in the Gulf Council countries companies. The main goal of the paper is to examine empirically the determinants of organizational cultures (structure, strategy, leadership, and high-performance work), and their impacts on job performance. The relevance of the decision of this scientific problem is that organizational cultures are a relevant problem for the companies in the Gulf Council countries. The Investigation of the topic of organizational cultures and the job performance in the paper is carried out in the following logical sequence: The methodological tool of this contribution tries to measure the effect of organizational cultures, structure, strategy, leadership, and high-performance work on job performance. The main purpose of the research is focused on the empirical approach justified by the use of the structural equations. The paper presents the results of an empirical analysis which showed that the effect of organizational cultures, structure, strategy, leadership, and high-performance work exerts positive relationships on job performance. The results found suggest that structure and strategy as indicators of organizational cultures, job performance with a high-performance work practice. The results showed a positive impact between the variables and implied that organizational cultures in the Gulf Council countries companies have a positive and significant relationship with job performance. The results confirm the existence of positive relationship as significant between structure, strategy and job performance in the Gulf Council countries companies. The research empirically confirms and theoretically proves that organizational cultures are significant relationships with job performance. The results of the research can be useful for the Gulf Council countries companies to promote the organizational cultures for good job performance. Keywords: organizational cultures, strategy, leadership, high-performance work, job performance.


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