scholarly journals The association of positive mental health indicators and normal body weight, Belgian HIS 2018

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
K De Ridder ◽  
S Drieskens ◽  
S Demarest

Abstract Background An important health promotion goal is to maintain a normal body weight. However, knowledge about positive mental health indicators that might be associated with normal weight is scarce. The aim is to study positive mental health indicators and normal weight in a cross-sectional national representative population sample. Methods Study participants included adults aged ≥ 18 year (n = 6643) of the Belgian Health Interview Survey (HIS) 2018. Mental health indicators were having no psychological distress (GHQ-12<2), no self-reported anxiety or depression (EQ_5D), medium to high vitality (SF-36 vitality scale) and high to medium level of life satisfaction. BMI was calculated on self-declared height and weight. The associations were assessed through logistic regression taking into account confounding and effect modification by age, gender, educational level, health status, physical activity, daily eating of fruit and vegetables and daily consuming sugared soft drinks or sweet/salty snacks. Results 50.1% had a BMI≥25. In the crude models, all indicators were negatively associated with being obese, but there was no association between having a normal weight (versus overweight and obesity) and absence of psychological distress, absence of anxiety and depression, and medium to high vitality. Medium to high level of life satisfaction was associated with normal weight in the fully adjusted model (OR 1.3; 95%CI 1.0-1.6) but when stratified, medium to high life satisfaction was associated with normal weight only among high educated women (OR 1.8; 95%CI 1.1-2.9), but not among men and low educated women. Surprisingly, among low educated women, having no psychological distress was negatively associated with normal weight (OR 0.7; 95%CI 0.5-0.9). Conclusions These preliminary results showed a variable impact of gender and educational levels on the association between positive mental health indicators and normal weight. Trends and distribution in society should be further explored. Key messages Although unequivocal associations with obesity, positive mental health is not clearly associated with normal body weight in today’s obesogenic society. The effect of a shift towards a higher BMI in society on mental health needs to be further explored.

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 409.2-409
Author(s):  
E. Strebkova ◽  
E. Tchetina ◽  
L. Alekseeva

Background:Currently, a large number of molecular biological and genetic markers are known to be involved in the development of osteoarthritis (OA). The mammalian target of rapamycin (mTOR) signaling pathway is responsible for chondrocyte proliferation, cartilage matrix production, and cell growth. OA is characterized by increased mTOR synthesis, which is accompanied by an increase in proliferative activity and destruction of chondrocytes. Obesity is an important factor in the progression of knee OA. The study of mTOR expression in patients with OA and obesity is an urgent task in the development of personalized OA therapy.Objectives:To determine the expression of mTOR in patients with knee OA in combination with obesity and normal body weight. To evaluate the effect of mTOR on the clinical manifestations of OA in patients with different body mass index (BMI).Methods:The study included 73 female patients aged 45-65 y.o. with Kellgren-Lawrence stage II-III knee OA. The patients were divided into 2 groups: group 1 (n=50) with obesity (BMI > 30 kg / cm2) and group 2 (n=23) with normal or increased body weight (BMI < 30 kg/cm2). The average age of patients with obesity is 56.5 ± 5.87 years, without obesity - 58.7 ± 5.43 years. Clinical manifestations were evaluated by a WOMAС. RNA was isolated from the patients ‘ blood samples, which was used to determine the expression of mTOR.Results:Patients with knee OA with and without obesity did not differ in age. OA develops at an earlier age in obese patients, than in non-obese patients (p < 0.001). Patients from 1 group had a high BMI > 30 kg/m2 at the onset of OA. Obese patients had more severe knee OA is significantly more often detected: Kellgren-Lawrence stage III was determined in 10% of obese patients and in 4.35% - without obesity (p < 0.001). Significantly higher values of the WOMAC index pain, stiffness, joint functional failure, and total WOMAC were observed in obese patients (p = 0.006, p = 0.039, p = 0.037, and p = 0.014, respectively). Obese patients had higher VAS pain scores (p < 0.05) compared to patients with a lower BMI. Obese patients had a higher mTOR expression (p < 0.05) of 8.02±8.62, compared to non-obese patients. High mTOR expression was associated with VAS knee pain (r=0.78; p < 0.05) and WOMAC pain (r=0.89; p<0.05) in obese patients (Table 1).Table 1.Correlation of m-TORParametersmTOR (1 group, n=50)mTOR (2 group, n=23)Body weightр > 0,05р > 0,05Pain (VAS)r=0,78; р<0,05p = 0,07; r = 0,45Pain (WOMAC)r=0,89; р<0,05р > 0,05Total WOMACр > 0,05р > 0,05Conclusion:Our study showed that patients with obesity and knee OA have higher rates of mTOR expression, compared to patients with normal body weight. High mTOR expression correlates with the severity of knee pain in obese patients. Thus, the evaluation of mTOR expression in obese patients and knee OA plays an important role in predicting the severity of clinical manifestations of OA, and may influence the choice of personalized therapy tactics for such patients.Disclosure of Interests:None declared


2021 ◽  
Vol 12 ◽  
Author(s):  
Agata Grzyb ◽  
Małgorzata Domagalska-Szopa ◽  
Andrzej Siwiec ◽  
Ilona Kwiecień-Czerwieniec ◽  
Andrzej Szopa

Background: One of the objective methods of assessing the level of cardiopulmonary capacity in overweight and obese children and adolescents is cardiopulmonary exercise testing (CPET).Aims: The purpose of present study is an evaluation of aerobic capacity in high body mass index (BMI) children and adolescents by comparing them with a normal weight control group by CPET.Methods and Procedures: The subjects were recruited from participants of the Program of Treatment for Overweight and Obese Children organized by a local pediatric rehabilitation center in Poland. Based on BMI for age and gender, two validation groups were selected: (1) a group of overweight children (n = 49) and (2) a group of obese children (n = 48). The study included also 53 normal weight participants as a reference group (REF). The study consisted of two parts: anthropometric measurements and CPET. The Godfrey protocol for CPET was applied.Outcomes and Results: In this study, obese children and adolescents showed similar absolute VO2peak values in liters per minute (1.64 L/min) compared to overweight children (1.48 L/min), but significantly higher than children with normal body weight (1.39 L/min). The obese children and adolescents presented lower VO2peak in relation to body weight (25.44 ml/kg/min) compared to their peers with normal body weight (36.5 ml/kg/min), and overweight children (29.18 ml/kg/min).Conclusion and Implications: The main finding of our study was recognition of significant differences between cardiopulmonary capacity parameters in obese children in comparison not only to normal weight peers, but to overweight, too.


Author(s):  
O.V. Sheshukova ◽  
A. V. Veretilnik

This paper presents the analysis of foreign and domestic literature on the current state of the epidemic of obesity and evidence of its association with oral disease. The aim of this study was to assess the hygienic and dietary habits of overweight and normal-weight young schoolchildren and their association with dental caries. Materials and methods. The study included 628 children aged 6-11 years studying at primary schools of Poltava. We measured anthropometric data, assessed physical development, collected anamnestic data of children and carried out clinical dental examination. The oral hygienic state was assessed by using the simplified hygienic Green-Vermillion index (1964). Results. According to the findings of anthropometric survey obtained, we found out that 32, 64% (205 children) of the children were overweight. Having analyzed the data obtained by the questionnaire, it is safe to say that there is no noticeable difference in the hygienic habits between the primary schoolchildren involved in the study. Only about 70% of them brush their teeth every day, but only 15% of children get assistance from their parents or siblings. Such data are alarming due to the fact that as young children usually cannot clean their teeth properly therefore children under 10 should be under the control or guidance of their parents when brushing the teeth. Dietary habits of the overweight and normal-weight children are significantly different. The index of hygiene in children with excess body weight was within 2.1 scores that corresponds to unsatisfactory hygiene; children with normal body weight demonstrated significantly lower indicators ranging within 1.8 scores. The results of the dental examination showed that the caries prevalence was 60.78% and 58.63% for children with normal weight and excessive weight, respectively. Those figures did not differ significantly from the indicated age group of children with excessive and normal body weight. The study of the caries intensity showed that in the normal-weight children the df + DMF index was 1.89 ± 0.01, and the overweight children had the df + DMF 1.82 ± 0.04 index: thus, no significant difference was revealed. Caries of temporary teeth in children with excessive body weight was significantly seldom detected than in the group of children with normal body weight (2.46 ± 0.05 and 2.82 ± 0.02, respectively). The results of examining children with overweight and obesity demonstrated significantly lower intensity index of complicated caries of temporary teeth (1.07 ± 0.04 and 1.28 ± 0.02, respectively). Conclusions. Consequently, there is no significant difference in the hygienic habits between normal-weight and overweight children. As for dietary habits, there is a significant difference revealed by questioning the children. There is no difference in the hygienic index in the children of these two groups. The prevalence of caries was within the normal limits. A significant difference has been found in determining the caries intensity of permanent teeth in young school children of the studied groups. It is noteworthy that lower rates of caries intensity and its complications affecting temporary teeth have been found out in the overweight children when compared with peers having normal body weight; the patterns in the growth of the caries intensity for permanent teeth in the overweight children have been determined as well. Mostly due to inadequate hygiene, lack of balanced nutrition and adherence to a diet rich in carbohydrates, young children are especially vulnerable category of dental patients.


1982 ◽  
Vol 11 (3) ◽  
pp. 203-233 ◽  
Author(s):  
A. H. Crisp

Disgust with ‘fatness' and a consequent preoccupation with body weight, coupled with an inability to reduce it to or sustain it at the desired low level, characterizes the abnormal normal weight control syndrome. Individuals remain sexually active in a biological sense and often also socially. Indeed their sexual behaviour may be as impulse ridden as is their eating behaviour, which often comprises phases of massive bingeing coupled with vomiting and/or purgation. The syndrome is unlike frank anorexia nervosa in that the latter involves a regression to a position of phobic avoidance of normal body weight and consequent low body weight control with inhibition of both biological and social sexual activity. In abnormal normal weight control there is a strong and sometimes desperate hedonistic and extrovert element that will often not be denied so long as body weight does not get too low. Individuals nevertheless feel desperately ‘out of control’ and insecure beneath their bravura. The syndrome is much more common in females than in males. There is a clinical overlap with anorexia nervosa and obesity in many cases as the disorder evolves. Depression, stealing, drug dependence (including alcohol) and acute self-poisoning and self-mutilation are common complications. Clinic cases probably only represent the tip of the iceberg of a much more widespread morbidity within the general population. Like anorexia nervosa and for the same reasons the disorder is probably more common than it used to be.


2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Anna Shalimova ◽  
Valentyna Psarova ◽  
Nataliia Kyrychenko ◽  
Maryna Kochuieva

Abstract The results of a number of studies have shown that in arterial hypertension (AH), G/T and T/T genotypes of the adiponectin gene (ADIPOQ) and Gly/Arg and Arg/Arg genotypes of the insulin receptor substrate 1 gene (IRS-1) are associated with a greater severity of metabolic disorders and hemodynamic parameters compared with G/G and Gly/Gly genotypes of these genes. The aim of the study: to evaluate the severity of cardiovascular remodeling and metabolic disorders in hypertensive obese patients in the simultaneous presence of two unfavorable genotypes of the ADIPOQ and IRS-1 genes. Methods: We examined 300 AH patients: 200 patients with AH and obesity, 50 patients with AH and normal body weight, 50 patients with AH and overweight, 40 patients with AH, obesity and type 2 diabetes mellitus (DM2), 30 healthy individuals. The polymorphisms of the ADIPOQ and IRS-1 was assessed by molecular genetic method. Results: It was found that in all groups of hypertensive patients, regardless of body weight and the presence of DM2, the simultaneous presence of two unfavorable genotypes of the ADIPOQ and IRS-1 genes occurred significantly more often than in healthy individuals: in 41% of AH patients with obesity, 30% of AH patients with normal weight, 40% of AH with overweight, 57.5% of AH with obesity and DM2 vs. 13.3% of healthy individuals. In hypertensive patients, in the presence of overweight and obesity, the frequency of combination of the two unfavorable genotypes of these genes was significantly higher than in AH patients with normal body weight. Conducting comparative evaluation of AH patients with obesity depending on the presence of two unfavorable genotypes or two protective genotypes of the ADIPOQ and IRS-1 genes showed that carriers of the combination of the G/T + T/T genotype of the ADIPOQ and the Gly/Arg + Arg/Arg genotype of the IRS-1 had a higher body mass index, more pronounced insulin resistance, cardiovascular remodeling, adipokine imbalance, impaired carbohydrate and lipid metabolism. Conclusions: In AH patients, the frequency of the simultaneous presence of two unfavorable polymorphisms of ADIPOQ and IRS-1 genes was higher than in healthy individuals. In AH patients with overweight and obesity, the frequency of combination of the two unfavorable genotypes of the ADIPOQ and IRS-1 genes was significantly higher than in normal body weight. The presence of a combination of two unfavorable genotypes of the ADIPOQ and IRS-1 genes in patients with AH and obesity was associated with a greater severity of cardiovascular remodeling and metabolic disorders compared with the combination of two protective genotypes of these genes.


2010 ◽  
Vol 56 (3) ◽  
pp. 47-51 ◽  
Author(s):  
L M Bershteĭn ◽  
I G Kovalenko

The current concept of obesity as a heterogeneous condition is discussed. Such interpretation provides a basis for distinguishing a group of obese subjects without metabolic disturbances (metabolically healthy obese (MHO) subjects) and another one including subjects with normal body weight and signs of hormonal and metabolic disorders (metabolically obese normal weight (MONW) subjects). A separate subgroup is represented by obese patients with deficit of muscular mass and force (sarcopenic obesity). Potential mechanisms underlying development of these conditions are considered along with selected applied aspects of this problem.


2020 ◽  
Vol 99 (4) ◽  
pp. 399-404
Author(s):  
Mikhail M. Kolokol’cev

Introduction. The body weight of the person characterizes features of the exchange, power, hormonal, etc. the processes happening in a human body. Deviations from normal parameters of body weight affects somatic, physical, mental human health. The analysis of morfofunctsional characteristics and motive features of youth students with insufficient body weight is relevant in connection with insufficient study of the matter. Material and methods. 1514 students of the Irkutsk University at the age of 17-21 years are examined. Anthropometrical and physiometric examination was preformed, the maintenance of muscle and fatty bulk in a body was determined, motive qualities of young men with the normal body weight and deficiency of weight with gradation “below an average” and “low” are considered. Results. The deficiency of body weight is revealed at 209 examined young men (13.8%), out of them 134 students (64.1%) have gradation of deficiency of body weight “below an average” and value of an index in the range of a sigma deviation from M = -1 σ to M = -2 σ and 75 young (35.9%) men - gradation “low” where value of an index less than A M = -2 σ. Reliable differences between morfofunctional indices and results in motive tests of the students having deficiency of body weight and normal weight students are established. Indices of anthropometrical and physiometric characteristics, motive tests, the maintenance of muscle and fatty bulk in a body of all young men having deficiency of body weight are lower in comparison with indices of the young men having normal body weight (p <0.05). The dependence between decrease in the level of development of motive qualities and reduction of body weight of students is noted. Conclusions. The received results allow correcting educational process on valeological and physical training of students of higher education institution with the use of integrative pedagogical methods and methods of training.


Author(s):  
M.M. Kolokoltsev ◽  
S.S. Iermakov

Purpose : to study the morphofunctional and motor characteristics of the organism of students with overweight and obesity. To compare these data with data of students with normal weight. Participants : it was examined students (females - n=1937; males - n=1302) of 17-21 year-olds. (Baikal region, Russia). It was performed an anthropometrical and physiometric examination of students. It was determined the content of muscle and fat mass in the component structure of a body. It was determined the motor qualities of students. Results : the indicators of anthropometrical and physiometric characteristics, results of motor action tests, the content of muscle and fat mass in a body of students with overweight and obesity are lower in comparison with the indicators of females and males with normal body weight (р<0.05). The integral criterion of physical fitness of students with overweight and obesity is lower in comparison with students with normal body weight (р<0.05). It is defined the direct dependence between the decrease in the level of physical fitness and increase in body weight of males and females. It was obtained data concerning interrelation of anthropometrical and functional characteristics with motor qualities of males and females with different body weight. Conclusions : Results of the research allow correcting physical training classes of youth. Such classes are focused on the differentiated decrease in fat mass content and increase in muscle mass in the component structure of students' bodies.


2021 ◽  
Vol 2021 ◽  
pp. 1-19
Author(s):  
Grzegorz K. Jakubiak ◽  
Kamila Osadnik ◽  
Mateusz Lejawa ◽  
Sławomir Kasperczyk ◽  
Tadeusz Osadnik ◽  
...  

Introduction. Obesity is one of the most important public health problems in the world. Among obese people, there are those who, apart from excessive body weight, do not exhibit other metabolic dysfunctions, have a lower risk of developing cardiovascular diseases (CVDs), and show lower mortality. According to the theory, they are referred as metabolically healthy obese (MHO), in contrast to metabolically unhealthy obese (MUO). Metabolic disturbances occurring with obesity have been well established to be associated with oxidative stress. Aim. The purpose of this study was to analyse the association between selected anthropometric and biochemical parameters with oxidative stress in MHO, MUO, and normal weight young adults. Material and Methods. Individuals with age between 18 and 36 years with no history of chronic diseases and use of medicaments, with or without obesity, participated in the study. Complete blood counts, biochemical measurements, and parameters of oxidative stress such as total antioxidant capacity (TAC), total oxidative status (TOS), oxidative stress index (OSI), serum concentration of malondialdehyde (MDA), ceruloplasmin, thiol groups and lipid hydroperoxides (LPH), concentration of lipofuscin (LPS) in erythrocytes, and the activity of superoxide dismutase (SOD) were measured. Results. 422 patients who met the inclusion criteria were enrolled in the study. Among the study participants, 208 people (49.29%) were offspring of patients with angiographically confirmed coronary artery disease. Among the participants, 16 patients have been included in the group of metabolically healthy obese (MHO) people and 61 patients in the group of metabolically unhealthy obese (MUO) people and 345 patients had normal body weight. Significant differences between metabolically unhealthy obese and normal weight patients, as well as between women and men, have been found. Conclusions. We showed significant differences in the selected parameters of oxidative stress between metabolically unhealthy obese (MUO) individuals and young volunteers with normal body weight as well as without significant medical history.


2020 ◽  
Vol 99 (4) ◽  
pp. 399-404
Author(s):  
Михаил Михайлович Колокольцев

Introduction. The body weight of the person characterizes features of the exchange, power, hormonal, etc. the processes happening in a human body. Deviations from normal parameters of body weight affects somatic, physical, mental human health. The analysis of morfofunctsional characteristics and motive features of youth students with insufficient body weight is relevant in connection with insufficient study of the matter. Material and methods. 1514 students of the Irkutsk University at the age of 17-21 years are examined. Anthropometrical and physiometric examination was preformed, the maintenance of muscle and fatty bulk in a body was determined, motive qualities of young men with the normal body weight and deficiency of weight with gradation “below an average” and “low” are considered. Results. The deficiency of body weight is revealed at 209 examined young men (13.8%), out of them 134 students (64.1%) have gradation of deficiency of body weight “below an average” and value of an index in the range of a sigma deviation from M = -1 σ to M = -2 σ and 75 young (35.9%) men - gradation “low” where value of an index less than A M = -2 σ. Reliable differences between morfofunctional indices and results in motive tests of the students having deficiency of body weight and normal weight students are established. Indices of anthropometrical and physiometric characteristics, motive tests, the maintenance of muscle and fatty bulk in a body of all young men having deficiency of body weight are lower in comparison with indices of the young men having normal body weight (p <0.05). The dependence between decrease in the level of development of motive qualities and reduction of body weight of students is noted. Conclusions. The received results allow correcting educational process on valeological and physical training of students of higher education institution with the use of integrative pedagogical methods and methods of training.


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