Determinants in the intention to use PrEP and PEP in University students
Abstract Background Veracruz, Mexico, was ranked as the second national place on HIV/AIDS incidence during 2019, with 28.5% corresponding to people between 15 and 24 years old. Post-Exposure Prohylaxis (PEP) is currently available in Mexico, whereas Pre-Exposure Prophylaxis (PrEP) hasn't been introduced as an actual alternative for mexican population. Research question: What are the determining factors in the intent to use PrEP and PEP in university students in a city with high risk of infection for HIV/AIDS? Methods An observational, prospective, cross-sectional and analytical study was conducted in Veracruz, Mexico between June and December 2019. University students in the cities of Veracruz and Boca del Río were included, selecting participants through non-probabilistic sampling. HIV/AIDS-65 test was applied to assess attitudes, self-efficacy and susceptibility. Awareness of the existence of PrEP and PEP, along with the willingness to use them, were assessed by a questionnaire formulated by the authors. The surveys were conducted through Google Forms®. The results were collected and analyzed with the SPSS Statistic® program. Results 565 students were included, of which 19.8% were aware of the existence of PrEP and 13.4% were aware of the existence of PEP. 20.3% would be willing to take the PrEP and 22.3% were willing to take the PEP in case of having risky sexual encounters. Willingness to use the PrEP if required, showed different susceptibility (47.7 ± 1.8 vs. 44.4 ± 20) among those who responded positively. Levels of knowledge, attitude, susceptibility and self-efficacy had no differences among those who accepted to use PEP and those who didn't (p > 0.05). The accordance between those who were aware of the existence of PrEP and their intention to use it had a Kappa of 0.17, while the one for using PEP was 0.13. Conclusions Better interventions are needed to improve awareness among university students to use PrEP and PEP since the high risk of HIV-transmission in Veracruz. Key messages We consider convenient to propose a reproductive health module to promote HIV-focused health in university students. We must carry out a program to promote the use of PrEP and PEP if required.