The Moderating Effect of Chronological Age on the Relation Between Neuroticism and Physical Functioning: Cross-Sectional Evidence From Two French Samples

Abstract Background Epigenetic clocks are composite markers developed to predict chronological age or mortality risk from DNA methylation (DNAm) data. The present study investigated the associations between four epigenetic clocks (Horvath’s and Hannum’s DNAmAge and DNAm GrimAge and PhenoAge) and physical functioning during a three-year follow-up. Methods We studied 63–76-year-old women (n = 413) from the Finnish Twin Study on Aging. DNAm was measured from blood samples at baseline. Age acceleration (AgeAccel) i.e. discrepancy between chronological age and DNAm age was determined as residuals from linear model. Physical functioning was assessed under standardized laboratory conditions at baseline and at follow-up. A cross-sectional analysis was performed with path models, and a longitudinal analysis was conducted with repeated measures linear models. A nonrandom missing data analysis was performed. Results In comparison to the other clocks, GrimAgeAccel was more strongly associated with physical functioning. At baseline, GrimAgeAccel was associated with lower performance in the Timed Up and Go (TUG) test and the six-minute walk test. At follow-up, significant associations were observed between GrimAgeAccel and lowered performance in the TUG, six-minute and 10-meter walk tests, and knee extension and ankle plantar flexion strength tests. Conclusions The DNAm GrimAge, a novel estimate of biological aging, associated with decline in physical functioning over the three-year follow-up in older women. However, associations between chronological age and physical function phenotypes followed similar pattern. Current epigenetic clocks do not provide strong benefits in predicting the decline of physical functioning at least during a rather short follow-up period and restricted age-range.

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COMPARISION OF DENTAL SCORING SYSTEM WITH RADIOGRAPHIC SKELETAL SYSTEM IN AGE ESTIMATION

JKCD ◽

10.33279/2307-3934.2019.9103 ◽

2019 ◽

Vol 9 (1) ◽

pp. 9-11

Author(s):

Sadaf Ambreen

Keyword(s):

Age Estimation ◽

Scoring System ◽

Skeletal Age ◽

Chronological Age ◽

Age Group ◽

Dental Age ◽

Scoring Method ◽

Cross Sectional ◽

Study Results ◽

Male Subjects

Objectives: To compare Demirjian Dental scoring method with Greulich-Pyle (GP) Skeletal method of age estimation in pubertal children. Materials and Methods: Sample of the study included 267 male healthy subjects of 11-16 years of age group.. Demirjian Scoring system was utilized to evaluate the orthopantomograms to assess their Dental age and the Hand-Wrist radiographs were analyzed to calculate the skeletal age by utilizing GP atlas. Chronological age was obtained from the date of birth of the subject .Both methods were compared with one another and with the chronological age. It was a cross-sectional study and only healthy male subjects without any clinical abnormalities were included in the study. Results: A total of 267 male subjects of 11-16 years of age group were assessed by Demirjian and Greulich Pyle Methods. Both were compared with Chronological Age. Data obtained was statistically analyzed and the Student “t” test was applied in the study population. The mean difference between Chronolgical age and dental age was 0.69years and that of chronological age and skeletal age was 0.87 years. It was observed from dental age assessment that it does not differ much from the skeletal age. Conclusion: It was concluded that Demirjian method of Age Estimation is more precise than Greulich Pyle method of Age Estimation. Furthermore both methods can be used selectively in Medicolegal cases to access bone age which can be easily correlated to chronological age.

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Cross‐sectional growth standards for captive baboons: I. Organ weight by chronological age

Journal of Medical Primatology ◽

10.1111/j.1600-0684.1993.tb00693.x ◽

1993 ◽

Vol 22 (7-8) ◽

pp. 400-414

Author(s):

Michael C. Mahaney ◽

M. Michelle Leland ◽

Sarah Williams‐Blangero ◽

Yolan N. Marinez

Keyword(s):

Organ Weight ◽

Chronological Age ◽

Cross Sectional ◽

Growth Standards

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Associations Between Children’s Physical Activity, Pain and Injuries

Perceptual and Motor Skills ◽

10.1177/00315125211028455 ◽

2021 ◽

pp. 003151252110284

Author(s):

João Paulo de Aguiar Greca ◽

Thomas Korff ◽

Jennifer Ryan

Keyword(s):

Physical Activity ◽

Generalized Estimating Equations ◽

Weight Status ◽

Cross Sectional Study ◽

Moderating Effect ◽

Sectional Study ◽

Cross Sectional ◽

Excessive Weight ◽

Objectively Measured ◽

Children’S Physical Activity

Our aim in this study was to investigate the relationships between physical activity (PA), pain, and injury among children. Secondarily, we examined whether these relationships differed between children with normal versus excessive weight or obesity. This was a cross-sectional study of 102 children (57 girls) aged 8–12 years old. We assessed the prevalence of moderate and vigorous PA using accelerometry over a seven-day period. We examined the associations between moderate PA, vigorous PA, pain presence, and injury presence using generalized estimating equations with a logit link and binomial distribution. We adjusted the obtained models for potential confounders and explored the moderating effect of weight status. We found no association between moderate PA and pain, but time spent in vigorous PA was associated with pain. Neither moderate or vigorous PA were associated with injury, and there was no moderating effect of weight status in these relationships. In summary, we found that objectively measured vigorous PA is associated with pain among 8–12 year old children. While these results should be replicated in longitudinal studies, they suggest that an association between vigorous PA and pain should be considered when developing PA interventions for children.

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Factors beyond Workplace Matter: The Effect of Family Support and Religious Attendance on Sustaining Well-Being of High-Technology Employees

Healthcare ◽

10.3390/healthcare9050602 ◽

2021 ◽

Vol 9 (5) ◽

pp. 602

Author(s):

Ing-Chung Huang ◽

Pey-Lan Du ◽

Long-Sheng Lin ◽

Tsai-Fei Lin ◽

Shu-Chun Kuo

Keyword(s):

Family Support ◽

Work Engagement ◽

Spillover Effect ◽

High Technology ◽

Well Being ◽

Moderating Effect ◽

Religious Attendance ◽

Subjective Well Being ◽

Cross Sectional ◽

Support Work

Background: Apart from the workplace, drawing support from family and religion is critical to maintaining the well-being of high-technology employees. Relying on the job demands-resources model and the positive affective spillover effect, the aim of this study was to investigate the mediated relationship of family support, work engagement and subjective well-being, and the moderating effect of religious attendance on the mediated relationship. Methods: A cross-sectional research design was adopted. Mediation and moderated mediation were tested using the PROCESS macro v3.5 for the SPSS supplement. Purposive sampling was used for the distribution of questionnaires to high-technology employees in Taiwan. Results: Results from the data of 603 high-technology employees indicated that family support, work engagement, and subjective well-being exhibited a significant mediated relationship, and the mediated relationship was stronger among individuals with religious attendance experience. Conclusions: This study emphasizes the driving effect of family support on high-technology employee well-being and the moderating effect of religious attendance as a situational strength. We recommend closely attending to employee well-being because doing so is conducive to both the personal quality of life of employees and the sustainable development of organizations.

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The Contribution of Level of Cognitive Complexity and Pubertal Timing to Behavioral Risk in Young Adolescents

PEDIATRICS ◽

10.1542/peds.95.4.528 ◽

1995 ◽

Vol 95 (4) ◽

pp. 528-533

Author(s):

Donald P. Orr ◽

Gary M. Ingersoll

Keyword(s):

Risk Behaviors ◽

Cognitive Complexity ◽

Pubertal Timing ◽

Health Risk Behaviors ◽

Self Report ◽

Chronological Age ◽

Behavioral Risk ◽

Young Adolescents ◽

School Students ◽

Cross Sectional

Purpose. To determine the unique contributions of cognitive complexity and pubertal timing to participation in behavioral risk (substance use, sexual activity, school and legal problems) among young adolescents. Design. Cross-sectional with cohort replication. Methods. Two cohorts of middle school students in grades eight and nine in a midwestern school district completed a self-report questionnaire in 1987 and 1989. Measures of behavioral and emotional risk, cognitive complexity and pubertal timing relative to peers were included. Results. Complete data were available for 817 and 796 students in each cohort year. Gender, race, level of cognitive complexity and pubertal timing each contributed significantly to the variance in behavioral risk independent of chronological age (P < .0001). Boys, whites, those at lower levels of cognitive complexity and those who began pubertal maturation earlier than peers, were at significantly greater risk. Adolescents who demonstrated higher levels of cognitive complexity and those who began puberty later compared to peers participated in a smaller array of risk behaviors, independent of chronological age. Implications. Pediatricians should consider adolescents at lower levels of cognitive complexity (concrete thinking) and those who begin puberty earlier at greater risk for participation in health risk behaviors. Preventive health counseling tailored to the needs of this group may be most beneficial.

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Sensitivity and Specificity of Mandibular Third Molar Calcification at Chronological Age and Hand Wrist Maturation Stage to Discriminate Between Female and Male at Pubertal Growth Period

The Open Dentistry Journal ◽

10.2174/1874210602115010551 ◽

2021 ◽

Vol 15 (1) ◽

pp. 551-557

Author(s):

Endah Mardiati ◽

Ira Komara ◽

Himawan Halim ◽

Dikdik Kurnia ◽

Ani Melani Maskoen

Keyword(s):

Sensitivity And Specificity ◽

Third Molar ◽

Growth Period ◽

Chronological Age ◽

Maturation Stage ◽

Cross Sectional ◽

Pubertal Growth ◽

Mandibular Third Molar ◽

Significant Difference ◽

Stage D

Background: The mandibular third molar is the last tooth that is not completely developed by the time pubertal growth has been finished. Maturation of the mandibular third molar is one of the physiological maturation indicators that can be used to determine the stage of pubertal growth. Objective: The aim of the study was to determine the sensitivity and specificity of mandibular third molar calcification at chronological age and hand wrist maturation stage to discriminate between female and male at pubertal growth period. Methods: It is a retrospective study with a cross-sectional approach using panoramic and hand-wrist digital radiographs of 279 females and 144 males, age 8-17 years, with a total of 423 panoramic radiographs and 423 hand-wrist radiographs. Statistical analysis was performed using Excel Mega Stat. ANOVA to analyze the differences between mandibular third molar calcification at chronological age and hand-wrist maturation stage, and t-test was used to analyze the differences between females and males. Spearman rank correlation was used for the analysis of the correlation between mandibular third molar calcification with chronological age and hand-wrist maturation stage; sensitivity and specificity were used to discriminate the pubertal growth period between mandibular third molar calcification and hand-wrist maturation stage. Results: There were significant differences found in mandibular third molar crown maturation stage B and C, but no significant difference was observed between mandibular third molar stage A, D, E, F, G and H, between females and males. The highest percentage of mandibular third molar crown formation in females was observed at stage D (6.68%) at MP3u, and in males, it was observed at stage D (8.83%) at SMI-4. The highest percentage of root formation in females was stage E (8.24%) at the SMI-10 stage, and males stage F (4.86%) at MP3u. The correlation was observed between mandibular third molar calcification with hand-wrist, females 0.22 and males 0.43, and chronological age 0.60 for females and 0.69 for males. The highest sensitivity of mandibular third molar calcification of 97.0% was observed in female at SMI-4 of hand-wrist maturation with specificity of 100%, while in male, a sensitivity of 94.5% was observed at SMI-2 stage with a specificity of 99.99%. Conclusion: There were significant differences found in mandibular third molar calcification between females and males except for stage B and stage C; weak correlation was observed between mandibular third molar calcification and hand-wrist, and moderate correlation was observed with chronological age. The sensitivity and specificity in females and males indicate that mandibular third molar calcification is only useful for diagnosing the pre-pubertal growth phase.

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Learning to stay employable

10.31235/osf.io/ha8v9 ◽

2018 ◽

Author(s):

Dominik Emanuel Froehlich ◽

Simon Beausaert ◽

Mien Segers ◽

Maike Gerken

Keyword(s):

Informal Learning ◽

Indirect Effects ◽

Learning Activities ◽

Chronological Age ◽

Cross Sectional ◽

Mediation Effects ◽

Older Employees ◽

Welfare Systems ◽

Formal And Informal Learning ◽

The Relationship

Purpose – The purpose of this paper is to examine the effects of chronological age and formaland informal learning activities on employability. Furthermore, indirect effects of age on employabilityvia learning activities were tested.Design/methodology/approach – The authors conducted quantitative, cross-sectional surveyresearch (n¼780) in three Dutch and Austrian organizations to study the relationship betweenchronological age, formal and informal learning activities, and employability using structural equationmodeling.Findings – The authors find that both formal and informal learning increase employees’ employability.However, each type of learning contributes to different components of employability. Additionally, theauthors find indirect effects of chronological age on employability via formal learning.Research limitations/implications – The results question the focus on chronological age inorganizational and political decision making and contribute new insights for the management of anincreasingly older workforce.Practical implications – The findings question the predominant use of chronological age asdecisive criterion in organizational and national policies and call for closer examination of stereotypesagainst older employees. Employees should be supported in pursuing learning activities – irrespectiveof their chronological age. The implications of limiting employees’ access to formal learning activitiesmay limit their future employability. Individual employees, however, are in control of their informallearning activities, and this is a very important lever to maintain and develop employability.Social implications – Given the increasing dependency of social welfare systems on older people’sactive participation in the labor market, this study stresses that it is not chronological age per se thataffects people’s employability. This diverges from the way of how chronological age is used in policymaking.Originality/value – This study contributes further evidence for the relationships of age and formaland informal learning on employability. Additionally, it extends previous literature by examiningdifferent effects on different facets of employability, criticizing the prevalent use of chronological age,and investigating potential mediation effects.

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The Relationships between Attitudes, Subjective Norm and Hiring Intention - Does Age Make a Difference?

Sustainable Business and Society in Emerging Economies ◽

10.26710/sbsee.v1i2.1014 ◽

2019 ◽

Vol 1 (2) ◽

Author(s):

Claudia Lau ◽

Choong Yuen Onn ◽

Thamil Durai a/l Chelliah ◽

Chan Ling Meng

Keyword(s):

Older Workers ◽

Structural Equation ◽

Participation Rate ◽

Subjective Norm ◽

Moderating Effect ◽

Foreign Workers ◽

Business Organizations ◽

Cross Sectional ◽

Labour Shortage ◽

The Relationship

Objective: Malaysia is currently facing a phenomenon where a growing portion of its older population experiencing a decline in their employment participation rate. Simultaneously, most job vacancies are filled by foreign workers as a result of a labour shortage. One of the ways to substitute foreign workers is to utilise skilfully and experienced older workers. However, such requires the willingness of business organizations to hire these workers. Therefore, the main objective of the present study is to predict the relationship of managers’ attitudes and subjective norm with their intention to hire older workers, with age as a moderating variable. Methodology: The Theory of Planned Behaviour was identified to include the age of respondents as the moderator on the relationships between attitudes and hiring intention. Cross-sectional data were collected from managers of business organizations via personal administered quantitative surveys questionnaire. Hypotheses were tested using structural equation modelling (SEM-PLS). Results: The response rate was 78% (n=468). The research model accounted for a moderate portion of the variance in overall hiring intention (R2=0.377) and future hiring intention (R2=0.392). The findings suggested that: (1) attitudes and subjective norm are related to overall hiring intention and future hiring intention; (2) age has a moderating effect on the relationship between attitudes and overall hiring intention, but there is no moderating effect on the relationship between attitudes and future hiring intention. Implication: The empirical result has important implications for human resource strategists, academic researchers and public policymakers as it serves as an additional fuel to combat the nation's acute labour shortage by hiring able and willing older workers.

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Network ties and transactive memory systems: leadership as an enabler

Leadership & Organization Development Journal ◽

10.1108/lodj-11-2015-0247 ◽

2017 ◽

Vol 38 (1) ◽

pp. 56-73 ◽

Cited By ~ 5

Author(s):

Dainelis Cabeza Pulles ◽

Francisco Javier LLorens Montes ◽

Leopoldo Gutierrez-Gutierrrez

Keyword(s):

Linear Regression Analysis ◽

Memory Systems ◽

Multiple Linear Regression Analysis ◽

Transactive Memory ◽

Moderating Effect ◽

Three Dimensions ◽

Network Ties ◽

Cross Sectional ◽

Transactive Memory Systems ◽

Content Type

Purpose The purpose of this paper is to study the relationship between network ties (NT) and transactive memory systems (TMS), observed through three dimensions – specialization (TMSS), credibility (TMSCR), and coordination (TMSCO) – in the presence of leadership (LDR) as a moderating variable, in university research-and-development (R&D) groups. Design/methodology/approach The data are composed of 257 university R&D groups. To confirm the hypotheses, the authors use multiple linear regression analysis with a moderating effect. Findings The conclusions show that the relationships between NT and two of the three dimensions of TMS (TMSCR and TMSCO) are significant when LDR is included as a moderating variable. Although the effect of TMSS is positive, it is not significant. Including the interaction element enables better explanation of two of the dimensions of TMS in the sector analyzed. Thus, LDR is perfectly applicable to the university R&D environment. Research limitations/implications This research has several limitations that suggest further possibilities for empirical research. The limitations include the cross-sectional nature of the research and the judgment of a single manager as the basis of the perception analyzed for each group. Practical implications The authors provide several implications for R&D practitioners. The results of this study could be validated in other universities in other geographic areas, enabling better generalization and applicability of the results. The results described may serve as a guide for group leaders of university R&D. This research helps us to see the importance of LDR in forming internal research networks that help researchers to perform common projects in order to obtain better results in the group. Thus, the groups provided better results to society. Originality/value No studies have tested the moderating effect of LDR in university R&D empirically. The results provide information to fill this gap and demonstrate the applicability of LDR as a key element in the organization, improvement, and cohesion of R&D groups.

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