scholarly journals Age and Daily Positive Events Moderate the Link Between Depressive Symptoms and Inflammation

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 502-502
Author(s):  
Jin Wen ◽  
David Almeida ◽  
Nancy Sin
Keyword(s):  
Depressive Symptoms ◽  
Depression Scale ◽  
The United States ◽  
Epidemiological Studies ◽  
Positive Events ◽  
Younger Adults ◽  
Adult Lifespan ◽  
Reactive Protein ◽  
Day Range ◽  
Age Variations

Abstract Inflammation is a pathway underlying numerous aging-related conditions. Depression is related to elevated inflammation, whereas daily positive events have been linked to lower inflammation; these psychological experiences may interact with age to predict inflammation. The purpose of this study was to examine whether daily positive events moderate the association between depressive symptoms and inflammation in an adult lifespan sample. A sample of 343 adults ages 25-75 (55% women, 83% white) in the Midlife in the United States Refresher Study completed daily diary interviews for 8 evenings about their daily positive events. Depressive symptoms were assessed with the 20-item Center for Epidemiological Studies Depression scale, and blood samples were assayed for inflammatory markers interleukin-6 (IL-6) and C-reactive protein (CRP). On average, depression scores ranged from 0 to 44 (mean = 9.31, SD = 7.80), and participants reported 1.25 (SD = .70) positive events per day (range = 0–5). Depressive symptoms and daily positive events were separately associated with higher and lower log IL-6 and CRP, respectively. Depressive symptoms, daily positive events, and age interacted such that daily positive events predicted lower IL-6 (but not CRP) among midlife and older adults who reported lower depressive symptoms, whereas positive events were not related to inflammation among younger adults. Thus, these findings suggest that the protective association between daily positive events and inflammation was blunted when depressive symptoms were elevated and for younger adults. This work has implications for understanding age variations in the role of positive experiences in depression and inflammation.

Social relationship quality, depression and inflammation: A cross-cultural longitudinal study in the United States and Tokyo, Japan

2020 ◽  
pp. 002076402098160
Author(s):  
Benjamin Kaveladze ◽  
Allison Diamond Altman ◽  
Meike Niederhausen ◽  
Jennifer M Loftis ◽  
Alan R Teo
Keyword(s):  
United States ◽  
Depressive Symptoms ◽  
Relationship Quality ◽  
Social Relationships ◽  
Social Relationship ◽  
Depression Scale ◽  
The United States ◽  
Psychosocial Stressors ◽  
Psychological Traits ◽  
Reactive Protein

Background: Depression is an illness with biological, psychological, and social underpinnings, which may include the interplay of inflammation, psychological traits, stress, social relationships, and cultural background. Aims: This work examines the prospective associations between social relationship quality and depressive symptoms, and between social relationship quality and inflammatory outcomes in two distinct cultures. Methods: Data were obtained from two longitudinal, prospective cohort studies: Midlife in the United States (MIDUS), and Midlife Development in Japan (MIDJA) between 2004 and 2010. One thousand three hundred and twenty-seven community-based adults were included in analyses, 1,054 from the United States and 273 from Tokyo, Japan. Depressive symptoms (measured by the CES-D Depression Scale) and inflammation (measured by blood sample concentrations of the inflammatory biomarkers interleukin-6 and C-reactive protein) were the outcomes. Social relationship quality was the predictor. Culture, trait independence and interdependence, and psychosocial stressors were examined as moderators of the link between social relationship quality and depressive symptoms. Results: Higher social relationship quality was associated with lower depressive symptoms in the United States (β = −6.15, p < .001), but not in Japan (β = −1.25, p = .390). Social relationship quality had no association with inflammation. Psychosocial stressors moderated the link between social relationship quality and depressive symptoms in both the United States (β = −0.39, p = .001) and Tokyo (β = −0.55, p = .001), such that social relationship quality acted as a buffer against depressive symptoms as psychosocial stress increased. Conclusion: Improving the perceived quality of social relationships appears to be a stronger target for depression interventions in the United States than in Tokyo, Japan.

scholarly journals Depressive symptoms are associated with weight gain among women

2012 ◽  
Vol 42 (11) ◽  
pp. 2351-2360 ◽  
Author(s):  
A. R. Sutin ◽  
A. B. Zonderman
Keyword(s):  
Depressive Symptoms ◽  
Weight Gain ◽  
Hierarchical Linear Modeling ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Normal Weight ◽  
Linear Modeling ◽  
Hip Circumference ◽  
Adult Lifespan ◽  
Baltimore Longitudinal Study

BackgroundMany studies have linked depression and obesity; few have more than two assessments of depressive symptoms and adiposity to address the potential bidirectional relationship between adiposity and depressive symptoms from young adulthood through old age. We tested whether baseline depressive symptoms are associated with changes in weight, whether baseline adiposity is associated with changes in depressive symptoms, and whether these associations vary by sex.MethodParticipants (n=2251; 47% female) were from the Baltimore Longitudinal Study of Aging (BLSA). Using hierarchical linear modeling (HLM) on 30 years of data, the trajectory of adiposity and depressive symptoms over adulthood was estimated from >10 000 observations (mean=4.5 assessments per participant) of body mass index (BMI; kg/m2), waist circumference and hip circumference and >10 000 observations (mean=4.5 assessments per participant) of the Center for Epidemiological Studies Depression Scale (CES-D). Baseline depressive symptoms and adiposity were then tested as predictors of the trajectory of adiposity and depressive symptoms respectively. Additional analyses tested for sex-specific associations.ResultsSex moderated the association between depressive symptoms and weight gain such that women who experienced depressed affect had greater increases in BMI (binteraction=0.12, s.e.=0.04), waist (binteraction=0.22, s.e.=0.10) and hip circumference (binteraction=0.20, s.e.=0.07) across the adult lifespan, controlling for relevant demographic and behavioral covariates. Baseline adiposity was unrelated to the trajectory of depressive symptoms (median b=0.00) for both sexes.ConclusionsWomen who experience symptoms of depression tend to gain more weight across adulthood than men who experience such symptoms. Whether an individual was normal weight or overweight was unrelated to changes in depressive symptoms across adulthood.

scholarly journals Associations of Depressive Symptoms with All-Cause and Cause-Specific Mortality by Race in A Low-Socioeconomic Population: A Report from the Southern Community Cohort Study

2020 ◽  
Author(s):  
Yong Cui ◽  
Wei Zheng ◽  
Mark Steinwandel ◽  
Hui Cai ◽  
Maureen Sanderson ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Cohort Study ◽  
Depressive Symptoms ◽  
Low Socioeconomic Status ◽  
Cox Regression ◽  
Depression Scale ◽  
The United States ◽  
Epidemiological Studies ◽  
Low Socioeconomic ◽  
Specific Mortality

Abstract Depression is a leading cause of disability in the United States, but its impact on mortality among racially diverse, low-socioeconomic populations is largely unknown. Using data from the Southern Community Cohort Study, 2002-2015, we prospectively evaluated the associations of depressive symptoms with all-cause and cause-specific mortality in 67,781 black (72.3%) and white (27.7%) adults, predominantly with a low-socioeconomic status. Baseline depressive symptoms were assessed using the ten-item Center for Epidemiological Studies Depression Scale. The median follow-up time was 10.0 years. Multivariate Cox regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for mortality in association with depressive symptoms. Mild/moderate/severe depressive symptoms were associated with increased all-cause (HR=1.12, 95%CI: 1.03-1.22; HR=1.17, 95%CI: 1.06-1.29; HR=1.15, 95%CI: 1.03-1.28, respectively) and cardiovascular disease mortality (HR=1.23, 95%CI: 1.05-1.44; HR=1.18, 95%CI: 0.98-1.42; HR=1.43, 95%CI: 1.17-1.75, respectively) in whites but not in blacks (Pinteraction&lt; 0.001, for both). Mild/moderate/severe depressive symptoms were associated with increased external cause mortality in both races (HR=1.24, 95%CI: 1.05-1.46; HR=1.31, 95%CI: 1.06-1.61; HR=1.42, 95%CI: 1.11-1.81, respectively; for all subjects, Pinteraction=0.48). No association was observed for cancer mortality. Our study showed that depression-mortality associations differed by race and cause of death in individuals with a low-socioeconomic status.

scholarly journals The Impact of Work Hours on Depressive Symptoms among Koreans Aged 45 and Over

2021 ◽  
Vol 18 (3) ◽  
pp. 853
Author(s):  
Juyeong Kim ◽  
Eun-Cheol Park
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Social Services ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Work Hours ◽  
Middle Aged ◽  
Health Studies ◽  
Males And Females ◽  
The Impact

Background: Given the documented importance of employment for middle-aged and older adults’ mental health, studies of the association between their number of work hours and depressive symptoms are needed. Objectives: To examine the association between the number of work hours and depressive symptoms in Korean aged 45 and over. Methods: We used data from the first wave to fourth wave of the Korea Longitudinal Study of Aging. Using the first wave at baseline, data included 9845 individuals. Depressive symptoms were measured using the 10-item Center for Epidemiological Studies Depression scale. We performed a longitudinal analysis to estimate the prevalence of depressive symptoms by work hours. Results: Both unemployed males and females aged 45–65 years were associated with higher depressive symptoms (β = 0.59, p < 0.001; β = 0.32, p < 0.001). Females working ≥ 69 h were associated with higher depressive symptoms compared to those working 41–68 h (β = 0.25, p = 0.013). Among those both middle-aged and older adults, both males and females unemployed were associated with higher depressive symptoms. Those middle-aged female working ≥69 h were associated with higher depressive symptoms. Conclusions: An increase in depressive symptoms was associated with unemployed males and females working ≥69 h compared to those working 41–68 h. Although this association was found among middle-aged individuals, a decrease in depressive symptoms in both sexes was associated with working 1–40 h. Depressive symptoms should decrease by implementing employment policies and social services to encourage employers to support middle-aged and older adults in the workforce considering their sex and age differences.

scholarly journals Regular Exercise and Depressive Symptoms in Korean Older Adults

2021 ◽  
Vol 18 (1) ◽  
pp. 303
Author(s):  
Young-Mee Kim ◽  
Sung-il Cho
Keyword(s):  
Depressive Symptoms ◽  
Grip Strength ◽  
Multivariate Logistic Regression Analysis ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Hand Grip Strength ◽  
Regular Exercise ◽  
Older Individuals ◽  
Related Factors ◽  
Hand Grip

Prior studies have found that exercise has a positive effect on depressive symptoms in the general population. For older individuals, however, the association between exercise and depressive symptoms is conclusive. We examined whether regular exercise is related to depressive symptoms in 5379 Korean adults aged ≥55 years using data from a 2016 survey administered in the Korean Longitudinal Study of Aging. We used the 10-item Center for Epidemiological Studies–Depression scale to assess depressive symptoms. We performed a multivariate logistic regression analysis to investigate the relationship between regular exercise and depressive symptoms, adjusting for sociodemographic characteristics, self-rated health, number of chronic diseases, body mass index, hand-grip strength, physical disability, cognitive impairment, and health behavior. Interaction terms, including regular exercise and health-related factors, were also added. We found that a lack of regular exercise was significantly related to an increased frequency of depressive symptoms (OR = 1.18, 95% CI = 1.03–1.35). Moreover, hand-grip strength may increase the effect of regular exercise on depressive symptoms in individuals 65 years and older (OR = 1.01 vs. 1.70, 95% CI = 1.05–1.96). Our results suggest that it is important to encourage older individuals to exercise regularly as a means of relieving depressive symptoms.

The impact of cataract surgery on depressive symptoms for bilateral cataract patients in Ho Chi Minh City, Vietnam

2013 ◽  
Vol 26 (2) ◽  
pp. 307-313 ◽  
Author(s):  
Kien Gia To ◽  
Lynn B. Meuleners ◽  
Michelle L. Fraser ◽  
Dat Van Duong ◽  
Dung Van Do ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Depressive Symptoms ◽  
Cataract Surgery ◽  
Contrast Sensitivity ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Ho Chi Minh City ◽  
Bilateral Cataract ◽  
Vietnamese Population ◽  
The Impact

ABSTRACTBackground:Depression is common among older populations with cataract. However, the impact of cataract surgery on depression in both developed and developing countries remains unclear. The aim of this study is to determine the impact of cataract surgery on depressive symptoms and to examine the association between objective visual measures and change in depressive symptoms after surgery among a Vietnamese population in Ho Chi Minh City.Methods:A cohort of older patients with bilateral cataract were assessed the week before and one to three months after first eye surgery only or first- and second-eye cataract surgeries. Visual measures including visual acuity, contrast sensitivity, and stereopsis were obtained. Depressive symptoms were assessed using the 20-item Center for Epidemiological Studies-Depression Scale (CES-D). Descriptive analyses and a generalized estimating equations (GEE) analysis were undertaken to determine the impact of cataract surgery on depressive symptoms.Results:Four hundred and thirteen participants were recruited into the study before cataract surgery. Two hundred and forty-seven completed the follow-up assessment after surgery. There was a significant decrease (improvement) of one point in the depressive symptoms score (p = 0.04) after cataract surgery, after accounting for potential confounding factors. In addition, females reported a significantly greater decrease (improvement) of two points in depressive symptom scores (p = 0.01), compared to males. However, contrast sensitivity, visual acuity, and stereopsis were not significantly associated with change in depressive symptoms scores. First-eye cataract surgery or both-eye cataract surgery did not modify the change in depressive symptoms score.Conclusion:There was a small but significant improvement in depressive symptoms score after cataract surgery for an older population in Vietnam.

scholarly journals Length of gestation and depressive symptoms at age 60 years

2007 ◽  
Vol 190 (6) ◽  
pp. 469-474 ◽  
Author(s):  
Katri Räikkönen ◽  
Anu-Katriina Pesonen ◽  
Eero Kajantie ◽  
Kati Heinonen ◽  
Tom Forsén ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Risk Factor ◽  
Depressive Symptoms ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Birth Size ◽  
Gestational Length ◽  
Socioeconomic Characteristics ◽  
Duration Of Gestation ◽  
Length Of Gestation

BackgroundA non-optimal foetal environment, reflected in smaller birth size and shorter duration of gestation, is a risk factor for compromised health later in life.AimsTo examine whether smaller birth size and shorter gestation predict depressive symptoms.MethodA total of 1371 members of a cohort born between 1934 and 1944 at term (259–294 days' gestation) in Helsinki, Finland, completed the Beck Depression Inventory (BDI) and the Center for Epidemiological Studies Depression scale (CES–D) at an average age of 61.5 years (BDI) and 63.4 years (BDI and CES–D).ResultsGestational length predicted depressive symptoms linearly and independently of gender and birth weight: per day decrease in gestational length, depressive symptoms scores increased by 0.8-0.9% (95% CI 0.2-1.4, P<0.009). Weight, length and head circumference at birth showed no linear association with depression, adjusted for gender and gestational length. The results did not change when further controlled for socioeconomic characteristics at birth and in adulthood, age and body mass index in adulthood.ConclusionsSusceptibility to depressive symptoms may relate to shorter length of gestation.

scholarly journals The Relationship Between Reported Pain and Depressive Symptoms Among Adolescents

2018 ◽  
Vol 36 (2) ◽  
pp. 87-93 ◽  
Author(s):  
Sofie Borgman ◽  
Ida Ericsson ◽  
Eva K. Clausson ◽  
Pernilla Garmy
Keyword(s):  
Abdominal Pain ◽  
Back Pain ◽  
Depressive Symptoms ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Scale Scores ◽  
Prevalence Of Pain ◽  
The Relationship

Pain and depressive symptoms are common reasons for adolescents to contact the school nurse. The aim was to describe the prevalence of pain (headache, abdominal pain, and back pain) and depressive symptoms among adolescents and to examine whether there is an association between pain and depressive symptoms. This cross-sectional survey included students ( N = 639) in Sweden (median age: 16 years). Over half of the female participants (56%) and one third of male participants (33%) had weekly headaches, abdominal pain, or back pain. Almost every second girl (48%) and one in four boys (25%) had depressive symptoms (as measured by the Center for Epidemiological Studies Depression Scale, scores ≥ 16). There was a significant association between having pain (headache, abdominal pain, or back pain) and having depressive symptoms. It is of great importance for school nurses to adequately identify and treat the cause of pain and other factors contributing to depression.

scholarly journals Socio-demographic characteristics and co-occurrence of depressive symptoms with chronic diseases among older adults in China: the China Longitudinal Ageing Social Survey

2019 ◽  
Author(s):  
Zhenjie Wang ◽  
Hanmo Yang ◽  
Zhanyuan Guo ◽  
Bei Liu ◽  
Shen Geng
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Chronic Diseases ◽  
Odds Ratio ◽  
Logistic Regression Model ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Education Attainment ◽  
Cross Sectional ◽  
Social Survey

Abstract Background: The aim of the current study is to assess the cross-sectional association of chronic non-communicable diseases (hypertension, diabetes mellitus, arthritis, and cerebrovascular) with depressive symptoms among older adults in China. Methods: Data was obtained from the China Longitudinal Ageing Social Survey (CLASS) conducted in 2014. A total of 7505 participants were included. Depressive symptoms status was assessed by 9-item Center for Epidemiological Studies Depression Scale (CES-D) Associations between depressive symptoms and chronic diseases, adjusting for so, demographics and chronic diseases risk factors were assessed by using logistic regression model. Results: We found negative associations between depressive symptoms and several socioeconomic factors, including education attainment and economic level. Widowed/divorced/ unmarried individuals are more likely to suffer from depressive symptoms. Hypertension (Odds ratio:1.29 [95%CI:1.16, 1.42]), diabetes (1.41 [95%CI:1.19,1.67]), arthritis (1.72 [1.52, 1.96]), and cerebrovascular disease (1.69 [1.41, 2.02]) were found to be associated with depressive symptoms. Conclusions: Most depressive symptoms cases were found to be significantly associated with chronic diseases. Our findings have provided evidence for understanding co-morbid depressive symptoms with chronic diseases, which could help clinicians to evaluate, diagnose and manage depression promptly.

scholarly journals Latent Profile Analyses of Depressive Symptoms in Younger and Older Oncology Patients

Assessment ◽  
2018 ◽  
Vol 27 (7) ◽  
pp. 1383-1398 ◽  
Author(s):  
Rebecca M. Saracino ◽  
Heining Cham ◽  
Barry Rosenfeld ◽  
Christian J. Nelson
Keyword(s):  
Depressive Symptoms ◽  
Older Patients ◽  
Latent Profile Analysis ◽  
Latent Class ◽  
Profile Analysis ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Class Differences ◽  
Patients With Cancer ◽  
Latent Profile

The aging of America will include a significant increase in the number of older patients with cancer, many of whom will experience significant depressive symptoms. Although geriatric depression is a well-studied construct, its symptom presentation in the context of cancer is less clear. Latent profile analysis was conducted on depressive symptoms in younger (40-64 years) and older (≥65 years) patients with cancer ( N = 636). The sample was clinically heterogeneous (i.e., included all stages, dominated by advanced stage disease). Participants completed questionnaires including the Center for Epidemiological Studies Depression Scale, which was used for the latent profile analysis. A four-class pattern was supported for each age group. However, the four-class pattern was significantly different between the younger and older groups in terms of the item means within each corresponding latent class; differences were primarily driven by severity such that across classes, older adults endorsed milder symptoms. An unexpected measurement issue was uncovered regarding reverse-coded items, suggesting that they may generate unreliable scores on the Center for Epidemiological Studies Depression Scale for a significant subset of patients. The results indicate that cancer clinicians can expect to see depressive symptoms along a continuum of severity for patients of any age, with less severe symptoms among older patients.

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