scholarly journals Executive Functioning, Emotion Regulation, and Negative Emotion in Suicidal Older Adults

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 712-712
Author(s):  
Rachel Waldman ◽  
Brian Liles ◽  
Dimitris Kiosses ◽  
Richard Zweig
Keyword(s):  
Older Adults ◽  
Emotion Regulation ◽  
Suicidal Ideation ◽  
Executive Functioning ◽  
Color Word ◽  
Negative Emotion ◽  
Cohen’S D ◽  
Complex Interactions ◽  
Older Inpatients ◽  
Cohen's D

Abstract Deficits in executive functioning, emotion regulation, and negative emotion have all been linked to suicidality. Yet, the complex interactions between these three factors and their relationships to suicidal behavior in older adults remain unclear. Participants (N = 39) were depressed middle and older adult (M = 62.0, SD = 9.41) inpatients with recent suicidal attempt or ideation, without psychotic depression or moderate or greater cognitive impairment (DRS>90). Participants were administered measures of executive functioning (Stroop and COWAT), emotion regulation (ERQ Suppression and Reappraisal; RRS-Brooding; UPPS- Premediation Scale), and negative emotion (PANAS-X), in addition to measures of depression (MADRS) and suicidality (C-SSRS). Results indicated that executive functioning was not significantly related to emotion regulation or negative affect, but measures of emotion regulation were related to negative emotion and frequency of suicidal ideation in bivariate analyses. Lower ERQ reappraisal tended to be associated with negative emotion (ß = -.392, p = .067) in multivariate analyses. Although comparisons were non-significant, effect sizes revealed that those who experienced daily suicidal ideation (C-SSRS) had lower reappraisal and higher brooding scores (Cohen’s d = 1.014 - 1.456), as well as higher executive functioning (Stroop Color-Word trial) and overall cognition (DRS) scores (Cohen’s d = 0.625 – 0.792) than less frequent ideators. Findings suggest that older inpatients with frequent suicidal ideation have poorer emotion regulation but may have more intact cognition and executive functioning than those with less frequent suicidal ideation.

scholarly journals Impact of l-citrulline supplementation on oxygen uptake kinetics during walking

2018 ◽  
Vol 43 (6) ◽  
pp. 631-637 ◽  
Author(s):  
John Ashley ◽  
Youngdeok Kim ◽  
Joaquin U. Gonzales
Keyword(s):  
Older Adults ◽  
Young Adults ◽  
Oxygen Uptake ◽  
Oxygen Uptake Kinetics ◽  
Uptake Kinetics ◽  
Oxygen Deficit ◽  
Moderate Intensity ◽  
Oxygen Cost ◽  
Cohen’S D ◽  
Cohen's D

Supplementation with l-citrulline (Cit) has been shown to improve muscle oxygenation and oxygen uptake kinetics during moderate- to high-intensity cycling in young men. The aim of this study was to test the hypothesis that Cit would improve oxygen uptake kinetics during walking in older and young adults. In a randomized, double-blind study, 26 (15 women, 11 men) adults between the ages of 20–35 years (n = 15) and 64–86 years (n = 11) completed 7-day periods of taking placebo and Cit (6 g/day) in a crossover manner. Participants walked on a treadmill at 40% heart rate reserve while pulmonary oxygen uptake was measured using indirect calorimetry. Net oxygen cost, mean response time (MRT), and the oxygen deficit were calculated before and after each supplement period. There was no significant change (P > 0.05) in net oxygen cost, MRT, or the oxygen deficit after Cit in older adults, while young adults showed a decrease (P = 0.05) in the oxygen deficit after Cit that tended (P = 0.053) to be different than the change after placebo. Sex-stratified analysis revealed that Cit decreased MRT (P = 0.04, Cohen’s d = 0.41) and the oxygen deficit (P < 0.01, Cohen’s d = 0.56) in men with the change after Cit being greater than the change after placebo (MRT: −4.5 ± 2.1 vs. 3.4 ± 2.1 s, P = 0.01; deficit: −0.15 ± 0.05 vs. 0.01 ± 0.05 L, P = 0.02). All oxygen uptake parameters were unchanged (P > 0.05) following Cit and placebo in women. Cit does not alter the oxygen cost of moderate-intensity walking in young or older adults, but Cit improved the rate of rise in oxygen uptake at exercise onset in men.

scholarly journals A-20 Metabolic Syndrome and Executive Functioning in Young, Middle-Aged, and Older Adults

2019 ◽  
Vol 34 (6) ◽  
pp. 879-879
Author(s):  
T Slonim ◽  
L Haase-Alasantro ◽  
C Murphy
Keyword(s):  
Older Adults ◽  
Metabolic Syndrome ◽  
Executive Functioning ◽  
Cognitive Performance ◽  
Test Performance ◽  
Color Word ◽  
Self Report ◽  
Metabolic Status ◽  
Middle Aged ◽  
Increased Risk

Abstract Objective Metabolic syndrome (MetS) is associated with increased rates of mortality and increased risk for developing dementia. Changes in brain structure and executive functioning have been reported within the literature. However, research examining cognitive performance in individuals with metabolic syndrome focuses primarily on older cohorts. As such, the effect of metabolic syndrome on cognitive functioning earlier in the lifespan is unclear. This research examined neuropsychological test performance and self-report measures in young, middle-aged, and older adults with and without MetS. Method Participants (n = 128) were categorized by age and metabolic status as follows: Young: n = 42, 52.4% Metabolic; Middle-Age: n = 41, 56.1% Metabolic; Older: n = 45, 51.1% Metabolic. Participants were administered the following cognitive assessments as part of a larger study: Delis-Kaplan Executive Function System (DKEFS) Color-Word Interference Test and Trail Making. Multivariate analyses of variance were used to examine the relationship between age group, metabolic status, and cognitive performance. Results As expected, older adults performed more poorly than young and middle-aged adults across neurocognitive assessments (p < .05). MetS adults performed more slowly on Color-Word Interference: Inhibition [F(1,114) = 5.26, p = .024, η2 = .05]; however, there were no additional significant differences between groups on cognitive tests in this sample size. Conclusions These findings suggest that aspects of inhibition might be impaired in MetS adults. Future studies aimed at investigating relationships between metabolic risk factors and inhibition may provide insight into effective intervention targets to delay or prevent metabolic syndrome.

scholarly journals Effect of a Biobehavioral Environmental Approach on Sleep in Low-Income Older Adults

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 35-35
Author(s):  
Junxin Li ◽  
Safiyyah Okoye ◽  
Lena Sciarratta ◽  
Sarah Szanton
Keyword(s):  
Older Adults ◽  
Low Income ◽  
Functional Disability ◽  
Sleep Onset ◽  
Intervention Group ◽  
Team Approach ◽  
Sleep Onset Latency ◽  
Significant Group ◽  
Cohen’S D ◽  
Cohen's D

Abstract Low socioeconomic status and disability are independent risk factors for disturbed sleep. The CAPABLE intervention used a multidisciplinary team approach of occupational therapist, nurse, and handyworker to reduce functional disability in low-income older adults. The 6-month intervention may benefit sleep as the intervention addressed multiple individual factors associated with sleep quality, including pain, depression, communication, mobility, strength, and balance. This study examined the effect of the CAPABLE intervention on actigraphy-measured sleep in a sub-sample of 73 older adults from the CAPABLE trial (26 intervention vs. 47 control). The sample was aged 75.8±7.45 years, 86.3% female, and 84.9% African American. No significant group differences in sleep parameters were found at 6-month, controlling for baseline values. The intervention resulted in a 5.56% increase in sleep efficiency (95% CI= [1.39, 9.71], Cohen’s d=0.54), and 7.39 minutes decrease in sleep onset latency (95% CI= [0.10, 14.5], Cohen’s d=0.41) within the intervention group at 6-months.

scholarly journals Fish oil supplementation reduces osteoarthritis-specific pain in older adults with overweight/obesity

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Julia C Kuszewski ◽  
Rachel H X Wong ◽  
Peter R C Howe
Keyword(s):  
Older Adults ◽  
Chronic Pain ◽  
Fish Oil ◽  
Surrogate Marker ◽  
Well Being ◽  
Microvascular Function ◽  
Trial Registration ◽  
Vascular Pathology ◽  
Cohen’S D ◽  
Cohen's D

Abstract Objectives OA is a leading cause of chronic pain and disability. Next to inflammation, vascular pathology has been hypothesized to play a role in its aetiology and progression. Owing to side effects and the low efficacy of pharmacological treatments, dietary supplements are popular as alternative treatments, but evidence of efficacy is limited. We tested whether fish oil and curcumin supplementation can reduce chronic pain and OA burden in older adults. Methods A 16-week randomized, double-blind, placebo-controlled, 2 × 2 factorial design supplementation trial with fish oil (2000 mg/day docosahexaenoic acid + 400 mg/day eicosapentaenoic acid), curcumin (160 mg/day) or a combination of both was undertaken in sedentary overweight/obese older adults. Secondary outcomes included treatment-induced changes in self-reported chronic pain and OA burden and whether changes were related to changes in small artery elasticity (surrogate marker for microvascular function), CRP (inflammatory marker) and well-being. Results The majority of participants (131 of 152) reported chronic pain, which was predominantly OA specific. Fish oil significantly reduced OA-specific pain (P = 0.002, Cohen’s d = 0.56) and burden (P = 0.015, Cohen’s d = 0.45) compared with no fish oil treatment; reductions were correlated with improvements in microvascular function and well-being. Curcumin, alone or in combination with fish oil, did not reduce pain measures. Conclusion Our findings indicate potential for fish oil to alleviate OA pain and burden in overweight/obese older adults. Further investigations should be undertaken in patients with clinically diagnosed OA to evaluate fish oil alone and as an adjunct to conventional pharmacotherapy and to investigate underlying mechanisms. Trial registration Australian and New Zealand Clinical Trials Register, https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=370788, ACTRN12616000732482p.

Effects of Tamoxifen and Exemestane on Cognitive Functioning of Postmenopausal Patients With Breast Cancer: Results From the Neuropsychological Side Study of the Tamoxifen and Exemestane Adjuvant Multinational Trial

2010 ◽  
Vol 28 (8) ◽  
pp. 1294-1300 ◽  
Author(s):  
Christina M. Schilder ◽  
Caroline Seynaeve ◽  
Louk V. Beex ◽  
Willem Boogerd ◽  
Sabine C. Linn ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adjuvant Therapy ◽  
Executive Functioning ◽  
Cognitive Functioning ◽  
Verbal Memory ◽  
Endocrine Treatment ◽  
Healthy Controls ◽  
Cohen’S D ◽  
Multinational Trial ◽  
Cohen's D

PurposeTo evaluate the influence of adjuvant tamoxifen and exemestane on cognitive functioning in postmenopausal patients with breast cancer (BC).Patients and MethodsNeuropsychological assessments were performed before the start (T1) and after 1 year of adjuvant endocrine treatment (T2) in Dutch postmenopausal patients with BC, who did not receive chemotherapy. Patients participated in the international Tamoxifen and Exemestane Adjuvant Multinational trial, a prospective randomized study investigating tamoxifen versus exemestane as adjuvant therapy for hormone-sensitive BC.ResultsParticipants included 80 tamoxifen users (mean age, 68.7 years; range 51 to 84), 99 exemestane users (mean age, 68.3 years; range, 50 to 82), and 120 healthy controls (mean age, 66.2 years; range, 49 to 86). At T2, after adjustment for T1 performance, exemestane users did not perform statistically significantly worse than healthy controls on any cognitive domain. In contrast, tamoxifen users performed statistically significantly worse than healthy controls on verbal memory (P < .01; Cohen's d = .43) and executive functioning (P = .01; Cohen's d = .40), and statistically significantly worse than exemestane users on information processing speed (P = .02; Cohen's d = .36). With respect to visual memory, working memory, verbal fluency, reaction speed, and motor speed, no significant differences between the three groups were found.ConclusionAfter 1 year of adjuvant therapy, tamoxifen use is associated with statistically significant lower functioning in verbal memory and executive functioning, whereas exemestane use is not associated with statistically significant lower cognitive functioning in postmenopausal patients with BC. Our results accentuate the need to include assessments of cognitive effects of adjuvant endocrine treatment in long-term safety studies.

scholarly journals Education Differentially Buffers Cognitive Performance in Black and White Older Adults

2018 ◽  
Vol 74 (8) ◽  
pp. 1366-1375 ◽  
Author(s):  
Kharine R Jean ◽  
Cutter A Lindbergh ◽  
Catherine M Mewborn ◽  
Talia L Robinson ◽  
Marissa A Gogniat ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Educational Attainment ◽  
Black Americans ◽  
Community Dwelling ◽  
Analysis Of Covariance ◽  
Cohen’S D ◽  
Global Cognitive Function ◽  
Cohen's D ◽  
The Impact

Abstract Objectives Given that black American older adults are more likely to have lower educational attainment and perform worse on cognitive tests than white Americans, we examined whether increased education would confer greater cognitive advantage to black Americans on measures of global and specific domains of cognitive function. Methods The sample included 522 community-dwelling older adults from a larger study. An analysis of covariance was conducted with race and education as between-participant factors and global cognition as the dependent variable. A multivariate analysis of covariance was conducted with five cognitive domains (immediate memory, visuospatial/constructional ability, language, attention, and delayed memory) as the dependent variables. Results Significant main effects indicated that black Americans, F(1,516) = 29.18, p < .001, and individuals with less education, F(1,516) = 44.93, p < .001, evidenced lower cognitive functioning, controlling for age and overall health status, and the interaction term reached statistical significance, F(1,516) = 7.95, p = .005. The impact of education on global cognitive function for black participants was more than twice as large (Cohen’s d = 1.30) than for white participants (Cohen’s d = .52). There was a significant race × education interaction for the cognitive domain of attention (p < .001) and a composite measure of non-memory domains (i.e., language, visuospatial/constructional, and attention; p < .001). Discussion Our findings suggest that educational attainment is particularly important for black Americans with respect to global cognitive function, attention, and non-memory domains.

Using humour as an extrinsic source of emotion regulation in young and older adults

2014 ◽  
Vol 67 (10) ◽  
pp. 1895-1909 ◽  
Author(s):  
Jonathan Harm ◽  
Sandrine Vieillard ◽  
André Didierjean
Keyword(s):  
Older Adults ◽  
Emotion Regulation ◽  
Beneficial Effect ◽  
Negative Emotion ◽  
Negative Feeling ◽  
Cognitive Demands ◽  
Age Related ◽  
Cognitive Distraction ◽  
Effective Form ◽  
Negative Feelings

It has been suggested that intrinsic abilities for regulating emotions remain stable or improve with ageing, but, to date, no studies have examined age-related differences in extrinsic emotion regulation. Since humour has been found to be an effective form of emotion regulation, we used a paradigm similar to that of Strick and colleagues (2009) with two objectives: to compare extrinsic humorous emotion regulation in young and older adults and to test whether the potential beneficial effect of humour on negative emotion is better explained by the cognitive distraction hypothesis or by the positive affect elicitation hypothesis. To this end, neutral, moderately, and strongly negative pictures followed by humorous, simply positive, or weird cartoons, controlled for both their funniness and cognitive demands, were presented to 26 young and 25 older adults with the instruction to report their negative feelings. When induced to feel moderately negative emotions, both young and older adults reported a lower negative feeling after viewing the humorous cartoons than after the other ones. This indicates that the extrinsic humorous emotion regulation skill remains stable with ageing and suggests that the beneficial effect of humour on emotional feeling cannot be seen as a purely cognitive distraction.

scholarly journals The Feasibility and Effectiveness of a Community-Based Intervention to Reduce Sedentary Behavior in Older Adults

2021 ◽  
pp. 073346482098791
Author(s):  
Kevin M. Crombie ◽  
Brianna N. Leitzelar ◽  
Neda E. Almassi ◽  
Jane E. Mahoney ◽  
Kelli F. Koltyn
Keyword(s):  
Older Adults ◽  
Sedentary Behavior ◽  
Physical Function ◽  
Sedentary Time ◽  
Controlled Trial ◽  
Community Dwelling ◽  
Control Group ◽  
Post Intervention ◽  
Cohen’S D ◽  
Cohen's D

The purpose of this study was to examine the effectiveness and feasibility of translating a 4-week “Stand Up and Move More” (SUMM) intervention by state aging units to older adults ( N = 56, M age = 74 years). A randomized controlled trial assessed sedentary behavior, physical function, and health-related quality of life (HRQoL) before and after the intervention. Participants included healthy community-dwelling, sedentary (sit > 6 hr/day) and aged ≥ 55 years adults. For the primary outcome, the SUMM group ( n = 31) significantly ( p < .05) reduced total sedentary time post-intervention by 68 min/day on average (Cohen’s d = −0.56) compared with no change in the wait-list control group ( n = 25, Cohen’s d = 0.12). HRQoL and function also improved ( p < .05) in the SUMM group post-intervention. Workshop facilitators indicated the intervention was easy to implement, and participants expressed high satisfaction. The SUMM intervention reduced sedentary time, improved physical function and HRQoL, and was feasible to implement in community settings.

scholarly journals Comparing Working Memory and Verbal Learning in Older Adult Musicians and Non-musicians

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 704-704
Author(s):  
Caroline Galloway ◽  
Jessica Strong
Keyword(s):  
Working Memory ◽  
Executive Functioning ◽  
Older Adult ◽  
Musical Training ◽  
Digit Span ◽  
Verbal Learning ◽  
Cognitive Test ◽  
Vocal Training ◽  
Cohen’S D ◽  
Cohen's D

Abstract Previous research suggests that learning or playing an instrument may benefit working memory and executive functioning. The literature also suggests vocal training or singing ability may increase proficiency in verbal learning and working memory. Despite the benefits of musical training, the underlying mechanisms remain unclear. Older adult participants (N=38, Mean age =70.2) provided their music training history and completed a cognitive test battery. Musicians were either instrumentalists and/or vocalists (N=24) or non-musicians (N=14). Independent t test analyses were run with the current modest sample size to compare scores in basic and complex attention and working memory (Digit Span Forward (DSF) and Digit Span Backwards (DSB, and Digit Span Sequencing (DSS)), and verbal learning and memory (California Verbal Learning Test-3 (CVLT)). Results found that musicians/singers had higher scores compared to non-musicians on DSS (t(32)= -1.96, Cohen’s d =.72, p =.058) and on CVLT delayed raw scores(t(32)= -1.98, Cohen’s d=.71, p=.056), both with a medium-large effect size. There were no significant differences found between musicians and non-musicians in DSF and DSB or on CVLT immediate recall/learning. The results suggest that musical training, either instrumental or vocal, may contribute to working memory and verbal memory in older adults. Both the Digit Span task and CVLT rely heavily on executive functioning ability, which may act as a mechanism or mediator between instrumental and vocal training and scores on these cognitive tasks.

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