PSVI-8 Effects of a mycotoxin deactivator on performance of gestating and lactating gilts fed diets containing added mycotoxins

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 398-399
Author(s):  
Sinthia Siqueira ◽  
Hébert De Brito ◽  
Wagner Araújo ◽  
Hélio Neves ◽  
Mara Benfato ◽  
...  

Abstract The present study aimed to evaluate the impact of a mycotoxin deactivator in diets containing added mycotoxins for gestating and lactating gilts on their performance. A total of 60 gilts (LD x LW) were used. After insemination the gilts were distributed among 3 dietary treatments according to a randomized block design: a negative control (CON); mycotoxin positive control (Myc); and a positive control added a mycotoxin deactivator (Myc+Deact 2 kg/ton; Unike®Plus, Adisseo). The total mycotoxins levels added to the diets 2 and 3 from d 75 of gestation until farrowing were: DON at 2.5 mg/kg, FBs at 10 mg/kg, and ZEA at 0.75mg/kg. Sows received the experimental diets from d 75 of gestation until weaning (i.e. 21 d). At farrowing, total number of piglets born, born alive, stillborn, and mummies were measured. Piglets were individually weighed 24-h post-farrowing, and at weaning to determine litter performance during lactation. The effects of diet composition, blocks and initial weight were tested according to a general linear procedure analysis of variance (GLM procedure of SAS). During gestation, treatments influenced (P = 0.022) sow mortality rate: CON had no mortality and Myc 15.8% and Myc+deact 10.5%. Same observation was made for the lactation period (P = 0.017): CON showed a lower mortality rate compared to the mycotoxin fed sows (5.0 vs. 31.2 vs. 11.8%, respectively for CON, Myc and Myc+deact). Sow milk production yield was greater (P = 0.021) in CON (11.66 vs. 9.53 vs. 9.67 kg/ d, respectively for CON, Myc and Myc+deact). As a consequence of that, treatments also influenced piglet (P = 0.047) and litter (P = 0.048) weight with a higher value for CON sows, followed by Myc+deact and Myc. Our findings showed that the use of the deactivator can mitigate the negative effects on performance when animals are subjected to diets contaminated by challenging levels of mycotoxins.

2016 ◽  
Vol 37 (4Supl1) ◽  
pp. 2677 ◽  
Author(s):  
Paula Rodrigues Oliveira ◽  
Fabiana Ramos Santos ◽  
Eduardo Ferreira Duarte ◽  
Gustavo Silva Guimarães ◽  
Nadiessa Sartori Carvalho Mattos ◽  
...  

This study aimed to test the effects of dietary Aloe vera and Symphytum officinale extracts added separately or in combination with symbiotics on the performance, nutrient utilization, serum biochemical parameters, biometrics, and intestinal histomorfometry of broilers. The experiment had a randomized block design with five treatments and six replicates of ten broilers each. Treatments were as follows: negative control and positive control (diet without and with antibiotic, respectively); 0.2% Aloe vera (AV); 0.2% Symphytum officinale (S); 0.2% functional supplement, composed of symbiotics fermented in Aloe vera and comfrey plant extracts (S+PE). At seven days of age, FI of birds fed the Aloe vera extracts diets were lower than that observed for birds consuming the diet with Symphytum officinale extract and S+PE. Broiler performance remained unaffected by treatments at others ages evaluated. At 10 to 14 days of age the lowest ADCDM ADCCP was shown in group feed NC. The highest ADCCP was observed in PC control group and in diets supplemented with Aloe vera and S+PE. Serum levels of cholesterol, triglycerides, and phosphorus were affected by addition of extracts at seven, 21, and 35 days of age. The longest duodenal villi were observed in broilers fed S+PE diets at seven days of age. Aloe vera and Symphytum officinale extracts and symbiotics can be used in broiler diets as an alternative to growth-promoting antibiotics.


2020 ◽  
Vol 25 (1) ◽  
pp. 22
Author(s):  
Rusliandi Rusliandi ◽  
Diah Wulandari Rousdy ◽  
Mukarlina Mukarlina

Humic acid is a humus compound found in peat soil. Humic acid can potentially be used as an anti-inflammatory compound. This study aimed to determine the effect of humic acid on the volume of foot mice edema and to find the best dose that can suppress the degree of edema volume. The animal object was Swiss mice weighing 25-30 grams and 3 months old. The study used Randomized Block Design (RBD) with positive control, negative control and humic acid treatment with dose 62.5 mg kg-1BW, 125 mg kg-1BW, and 250 mg kg-1BW. The result of this research showed that edema inhibition by the administration of humic acid dose 62,5; 125; 250 mg kg-1 had inflammatory inhibition percentage 2.67%, 13.34%, and 20.01% respectively in 5-hour observation. The best dose of humic acid to suppress inflammation in the mice's paw is a humic acid dose of 250 mg kg-1 compared with value 23.3% of sodium diclofenac as the positive control.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 43-43
Author(s):  
Madison R Wensley ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
Steve S Dritz ◽  
Mike D Tokach ◽  
...  

Abstract A total of 320 barrows (DNA 200×400, initially 11.3 ± 0.65 kg BW) were used in a 21-d growth trial evaluating the effects of feeding Trp biomass (CJ America-Bio, Downers Grove, IL) as a source of Trp on nursery pig performance. Pigs were weaned at approximately 21 d of age, placed in pens based on initial BW, and fed a common diet. On d 21 after weaning, pigs were weighed and pens were allotted to 1 of 4 dietary treatments with 5 pigs/pen and 16 replicates/treatment. Dietary treatments included a negative control (16% SID Trp:Lys), positive control (21% SID Trp:Lys from crystalline L-Trp), or diets containing Trp biomass to provide 21 or 23.5% SID Trp:Lys (included at 0.104 or 0.156% of the diet, respectively). Diets were corn-soybean meal based and contained 1.25% SID Lys with other AA set to meet or exceed NRC (2012) requirement estimates. The Trp biomass contained 69% Trp. Growth data were analyzed as a randomized complete block design using PROC GLIMMIX of SAS with pen as the experimental unit. Overall (d 0 to 21) pigs fed 21% Trp from L-Trp or Trp biomass had increased (P < 0.05) ADG compared to the control, with pigs fed the 23.5% SID Trp biomass intermediate. Pigs fed the 21% Trp from Trp biomass had improved (P < 0.05) G:F compared to the control with others intermediate. In conclusion, Trp biomass is a viable alternative to crystalline Trp, but further evaluation at higher inclusion levels is needed.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 78-79
Author(s):  
Zhong-Xing Rao ◽  
Mike D Tokach ◽  
Steve S Dritz ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
...  

Abstract Two experiments were conducted to determine the efficacy of commercial products on growth performance of nursery pigs fed high fumonisin diets. In Exp. 1,350 pigs (241 × 600; DNA; initially 9.9 kg) were used with 5 pigs per pen and 14 pens per treatment. Five dietary treatments consisted of a positive control (low fumonisin, 4 ppm fumonisin; FB1 + FB2), negative control (50 ppm fumonisin;) and the negative control with one of three products (0.3% of Kallsil Dry, Kemin Industries Inc., Des Moines, IA; 0.3% of Feed Aid Wide Spectrum, NutriQuest, Mason City, IA; 0.17% of Biofix Select Pro, Biomin America Inc., Overland Park, KS). Diets were fed for 14 d. Pens were assigned to treatments in a randomized complete block design with initial weight as the blocking factor. Data were analyzed using nlme package in R program (version 3.5.2) with pen as experimental unit. Pigs fed the negative control, or diets with Kallsil Dry or Feed Aid had decreased (P&lt; 0.05) ADG, ADFI, and G:F compared with those fed the positive control and diet with Biofix. Pigs fed the positive control diet had decreased (P&lt; 0.05) d 14 serum sphinganine to sphingosine (Sa:So) ratio than those fed other diets. In Exp. 2, 300 pigs (241 × 600; initially 10.4 kg) were used and fed experimental diets for 28 d. Procedures were similar to Exp. 1 except there were 12 replicates per treatment and diets contained 30 ppm fumonisin. Pigs fed the negative control, or diets with Kallsil Dry or Feed Aid had decreased (P&lt; 0.05) ADG and G:F, and greater (P&lt; 0.05) d 14 and 28 Sa:So ratios compared with the positive control and diet with Biofix. In summary, adding Biofix to high fumonisin diets mitigated the negative effects of fumonisin while Kallsil Dry and Feed Aid did not.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 215-216
Author(s):  
Payton L Dahmer ◽  
Tamra Kott ◽  
Alison Crane ◽  
James Lattimer ◽  
Cassandra K Jones

Abstract Two experiments were conducted to evaluate corn dried distiller’s grains with solubles (DDGS) and corn gluten feed (CGF) as replacements for soybean meal (SBM) and determine the impact of an ionophore on Boer goat growth performance and carcass characteristics. In Exp. 1, 75 Boer-goat kids (initial BW 26.9 ± kg) were allotted to one of 5 dietary treatments: 1) Negative control (100% SBM, 0% DDGS and 0% CGF; 100SBM); 2) Positive control (100% DDGS, 0% CGF and 0% SBM; 100DDGS); 3) 66% DDGS, 33% CGF and 0% SBM (66DDGS/33CGF); 4) 66% CGF, 33% DDGS and 0% SBM (33DDGS/66 CGF); and 5) 100% CGF, 0% DDGS and 0% SBM (0DDGS/100CGF). Dietary treatment did not impact (P ≤ 0.21) growth. In Exp. 2, 72 Boer-goat kids (initial BW 21.7 ± kg) were allotted to one of 4 dietary treatments in a 2 X 2 factorial with 2 protein sources and 2 ionophore inclusions: 1) SBM/no ionophore (SBM-NI); Diet 2) SBM with ionophore (SBM-I); Diet 3) DDGS/no ionophore (DDGS-NI); and Diet 4) DDGS with ionophore (DDGS-I). On d 21, goats were split into 2 groups according to their protein source and fed an additional d 10 (Group 1: DDGS-I; Group 2: SBM-I). The 15 heaviest goats from each group were harvested and carcass data collected. The protein source X ionophore interaction was not significant (P ≥ 0.15) for any measured response criteria. Goats fed a diet with SBM had significantly increased (P = 0.04) ADG compared to goats fed DDGS. No evidence of difference was observed (P ³ 0.10) for ADFI or G:F. Dietary treatment did not impact (P &gt; 0.05) carcass characteristics. In summary, these data suggest that corn co-products can be economically included in Boer-goat diets, however their impact on growth performance is variable compared to that of soybean meal.


2020 ◽  
Vol 14 (01) ◽  
pp. 23
Author(s):  
Inten Sharon Datuyanan ◽  
Bistok Hasiholan Simanjuntak ◽  
Andree Wijaya Setiawan ◽  
Yoga Aji Handoko

As food contains vitamin, mineral and antioxidant, beetroot (Beta vulgaris L.) had beneficial for health. Although beetroot contains a lot of nutritional value, beetroot is less liked by the public because of an earthy taste. For this reason, it needs innovation of the beetroot processing into products that can be accepted by the public, such as beverage fruit drink with food additives. In this study, beetroot juice with food additives, i.e. lemongrass, and turmeric mango was expected to improve taste and acceptable consumer. This study were aimed to analyze the effect of lemongrass and turmeric mango on physicochemical characteristics and determine the organoleptic quality of beetroot juice. This study used a Randomized Block Design (RBD) with the addition of lemongrass and turmeric mango respectively 1%, 3%, 5% concentration in the beetroot juice. Negative control used beetroot juice plain and the positive control used beet juice plus honey. Data were analyzed by variance (ANOVA), if the results obtained were significantly different, the DMRT continuing with 5% significant level. The results showed that the addition of lemongrass and turmeric mango with the concentration of each 1%, 3%, 5% effect on the physicochemical characteristics and organoleptic beet juice. The highest total dissolved solids was 6.92oBrix and the highest betacyanin content of 10.26 mg/L occurred at the addition of 5% turmeric mango. The highest pH value was shown in the negative control (beetroot juice plain) with an average of 6.52. The highest vitamin C content found in the addition of 1% lemongrass about 6.16 mg/100g. The results also showed that the organoleptic beet juice with the addition of 1% lemongrass and the positive control (beet juice plus honey) as a sample that it the most preferred by the panelists. Keywords: beetroot juice, lemongrass, physical-chemistry, organoleptic, turmeric mango


EUGENIA ◽  
2011 ◽  
Vol 17 (2) ◽  
Author(s):  
Aenul Latifah ◽  
. Kustantinah ◽  
Loekas Soesanto

ABSTRACT The green house research aimed to know the best isolate of T. harzianum in controlling Fusarium wilt , shallot production, and the effect of T. harzianum application time in suppressing the disease. Randomized block design was used with twelve treatments. Each treatment was replicated three times. The treatments were negative control, positive control as wel as extract of ginger isolate, banana isolate, shallot isolate, potato isolate, and ginseng isolates. The treatments were  applied a week before or after inoculation of the pathogen. The result showed that the antagonist extract of ginger isolate applied a week before inoculation decreased the disease intensity by 43.854%. The antagonist extract application applied before or after inoculation were not significant difference . The antagonist of potato isolate extract was the best in increasing number of plants per clump and tuber fresh weight resulting  9.7503 and 13.133 g, respectively. The best extract in increasing root growth was shallot extract. The ginger isolate extract increased root length by 17.672%. Keywords: Trichoderma harzianum isolates, biological control, Fusarium wilt, shallot   ABSTRAK Penelitian rumah kasa ini bertujuan untuk mengetahui isolat T. harzianum yang paling baik dalam mengendalikan penyakit moler dan meningkatkan hasil bawang merah, serta pengaruh waktu pemberian T. harzianum dalam menekan penyakit moler. Rancangan yang digunakan adalah Rancangan Acak Kelompok (RAK), yang terdiri atas 12 perlakuan dengan 3 ulangan. Perlakuan yang dicoba adalah kontrol negatif (tanpa perlakuan T. harzianum dan  Fusarium oxysporum) dan kontrol positif (hanya dengan inokulasi F. oxysporum), serta ekstrak isolat jahe, pisang, bawang merah, kentang, dan ginseng yang diberikan 1 minggu sebelum atau sesudah inokulasi. Hasil penelitian menunjukkan bahwa ekstrak T. harzianum isolat jahe yang disiram sebelum inokulasi Fusarium oxysporum, mampu menurunkan intensitas penyakit sebesar 43,854%. Belum terlihat jelas pengaruh nyata pemberian ekstrak antagonis sebelum maupun sesudah inokulasi patogen. Ekstrak T. harzianum isolat kentang adalah isolat terbaik dalam meningkatkan jumlah anakan per rumpun dan bobot basah umbi, yaitu masing-masing 9,7503 dan 13,133 g, sedangkan ekstrak terbaik dalam pertumbuhan akar yaitu isolat bawang merah yang meningkatkan jumlah akar sebesar 57,452% dan ekstrak isolat jahe menunjukkan pengaruh terbaik meningkatkan panjang akar sebesar 17,672%. Eugenia Volume 17  No. 2  Agustus 2011 Kata Kunci: Isolat Trichoderma harzianum, pengendalian hayati, penyakit layu Fusarium, bawang merah


2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Zhong-Xing Rao ◽  
Mike D Tokach ◽  
Steve S Dritz ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
...  

Abstract Two experiments were conducted to determine the efficacy of various commercial products on growth performance of nursery pigs fed diets high in fumonisin. In experiment 1, 350 pigs (241 × 600; DNA, Columbus, NE; initially 9.9 kg) were used with five pigs per pen and 14 replicates per treatment. After weaning, pigs were fed common diets for 21 d before the experiment started. The five dietary treatments consisted of a positive control (low fumonisin), a negative control (60 mg/kg of fumonisin B1 + B2 in complete diet), and the negative control with one of three products (0.3% of Kallsil Dry, Kemin Industries Inc., Des Moines, IA; 0.3% of Feed Aid Wide Spectrum, NutriQuest, Mason City, IA; 0.17% of Biofix Select Pro, Biomin America Inc., Overland Park, KS). Diets were fed in mash form for 14 d and followed with a low fumonisin diet for 13 d. For the 14-d treatment period, pigs fed the positive control diet and Biofix Select Pro had greater (P &lt; 0.05) average daily gain (ADG), average daily feed intake (ADFI), and gain:feed (G:F) compared to those fed the high fumonisin negative control, or high fumonisin diets with Kallsil Dry or Feed Aid Wide Spectrum. Serum sphinganine to sphingosine ratios (SA:SO) were greater (P &lt; 0.05) in all pigs fed high fumonisin diets compared to the positive control. In experiment 2, 300 pigs (241 × 600; DNA; initially 10.4 kg) were used. Procedures were similar to experiment 1 except there were 12 replicate pens per treatment, high fumonisin diets contained 30 mg/kg fumonisin, and experimental diets were fed for 28 d. Similar to experiment 1, pigs fed the positive control diet and treatment with Biofix Select Pro had greater (P &lt; 0.05) ADG and G:F, and lower (P &lt; 0.05) serum SA:SO compared to pigs fed the high fumonisin negative control, or high fumonisin diets with Kallsil Dry or Feed Aid Wide Spectrum. In summary, pigs fed diets containing 60 mg/kg of fumonisin for 14 d or 30 mg/kg of fumonisin for 28 d had poorer ADG and G:F and greater serum SA:SO compared to pigs fed a diet with less than 5 mg/kg of fumonisin. Adding Biofix Select Pro to diets appeared to mitigate the negative effects of high fumonisin concentrations, while Kallsil Dry and Feed Aid Wide Spectrum did not.


2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 294-295
Author(s):  
Meghan P Thorndyke ◽  
Octavio Guimaraes ◽  
Matheus Medrado ◽  
Briana V Tangredi ◽  
Huey Yi Loh ◽  
...  

Abstract The objective of this experiment was to evaluate the effects of Mo source (feed or water) on performance and mineral status of cows and calves fed a forage-based diet for two years (DM basis: 6.6% CP; 0.14% S, 6.7 mg Cu/kg, 2.4 mg Mo/kg). Fifty-four cow-calf pairs were stratified by cow age, BW, and liver Cu and Mo status, and randomly assigned to one of six treatments. Treatments consisted of: 1) Negative control (NC; no supplemental Mo or Cu); 2) Positive control [PC: NC + Cu (3 mg Cu/kg diet DM from CuSO4·5H2O)]; 3) NC + 500 µg Mo/L from MoNa2O4·2H2O in drinking water (Mo 500-water); 4) NC + 1000 µg Mo/L of MoNa2O4·2H2O in drinking water (Mo 1000-water); 5) Mo 1000-water + 3 mg Cu/kg diet DM from CuSO4·5H2O (Mo 1000-water+Cu); and 6) NC + 3 mg Mo/kg diet DM from MoNa2O4·2H2O (3.0 Mo-diet). Cattle were allowed ad-libitum access to feed, water, and a protein supplement throughout the experiment. During the winter months animals were housed in three replicate pens per treatment and during the summer months animals were housed in separate pastures by treatment where cow and calf feed and water intake could be measured separately. Data were analyzed as a completely randomized block design. Throughout the experiment no signs of molybdenosis were observed. There was a treatment x time (P &lt; 0.01) interaction for cow liver Cu concentrations. Cows not receiving supplemental Cu had lower (P &lt; 0.01) liver Cu concentrations than cows receiving supplemental Cu. Cow and calf performance, calf mineral status, cow liver Mo, and plasma and milk Mo and Cu concentrations were similar across treatments. These data indicate that Mo supplemented in water or feed at concentrations used in this experiment had minimal impact on Cu status and overall animal performance.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 108-109
Author(s):  
Vitor Hugo C Moita ◽  
Márvio L Abreu ◽  
Bruno N Silva ◽  
Rhuan Chaves ◽  
Ronaldo Lucas S Tolentino ◽  
...  

Abstract The study aimed to evaluate the impact of the supplementation on post weaning diets of the conventional source of zinc oxide (ZnO) and/or a potentiated source of zinc oxide (PZnO) and different (P) levels on productive performance, incidence of diarrhea, (Zn) and (Cu) fecal excretion. Eighty-four pigs weaned at 21 days of age were allocated in a randomized block design with four dietary treatments [T1: no inclusion of ZnO and regular P levels (0.440%; 0.420%; 0.400%; 0.380%); T2: inclusion of ZnO and regular P levels (0.440%; 0.420%; 0.400%; 0.380%); T3: ZnO and PZnO and 10% low P levels (0.396%; 0.379%; 0.360%; 0.340%); T4: inclusion of the PZnO and 10% low P levels (0.396%; 0.379%; 0.360%; 0.340%)], with seven replications and three pigs/pen. The nutritional program was: (pre-starter 1: d 21 to 28; pre-starter II: d 28 to 35; starter I: d 35 to 49; and starter II: d 49 to 63). The Tukey test was adopted to compare the means (SAS, 9.3). From d 1 to 14, T2 improved ADG (P &lt; 0.05) and BW (P &lt; 0.05) at d 14. From the period of d1 to d28, pigs fed with T2 diets showed higher ADG (P &lt; 0.05), ADFI (P &lt; 0.05) and, consequently, higher BW (P &lt; 0.05) at d 28. From d 1 to 42, pigs fed with PZnO diet performed the highest ADFI (P &lt; 0.05). Evaluating overall data of diarrhea, T2 reduced the incidence of diarrhea (P &lt; 0.05). T4 reduced Zn and P fecal excretion during the period from d 7 to 28 (P &lt; 0.05). Therefore, the use of ZnO and PZnO provide the same performance results of piglets on the period from d 1 to 42 after weaning. Furthermore, the inclusion of PZnO reduces the Zn and P fecal excretion.


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