scholarly journals PSVI-28 Effects of Chinese herbal medicine and probiotics on the physicochemical properties of chicken

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 209-209
Author(s):  
Xiaofei Chen ◽  
Yunfen Zhu ◽  
Yongkang Yang ◽  
Jiqian Xiang ◽  
Hongqing Yin ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Statistical Significance ◽  
Chemical Properties ◽  
Control Group ◽  
Blank Control Group ◽  
Chinese Herbal ◽  
Poultry Breeding ◽  
Antibiotic Group ◽  
Physical And Chemical

Abstract Objective: In this study, we estimate the effects of probiotics, Chinese herbal medicine and antibiotics on chicken protein, fat, ash, some kind of amino acids and fatty acids, tenderness and other physical and chemical properties. Method: 240 hens were divided into six groups, including blank control group, probiotic group, antibiotic group, Chinese herbal medicine group (Three parallel groups were set in the Chinese herbal medicine group: 0.3%, 0.6% and 1%). Hens were fed on restricted diets for more than 120 days. Collecting six breast samples from each group randomly and assaying those items described in the objective. In this study, we performed some determination methods, such as HPLC, GC, Kjeldahl and Soxhelt Method. Data were collected by Excel and analyzed by SPSS18.0 software. The results were expressed as the mean ± SD. One-way ANOVA followed by Duncan’s test was performed to determine statistical significance. ResultThe results showed that the contents of protein, fat, amino acid and fatty acid in chicken were not different significantly among these groups (P > 0.05). So did the value of shear (P > 0.05). Inosine acid content in 0.6% & 1% Chinese herbal medicine group was increased significantly (P < 0.05). The ash value was decreased significantly in 1% Chinese herbal medicine group (P < 0.05). Significance and Innovation: There are many alternatives of antibiotics in livestock and poultry breeding based on Chinese herbal medicine in China. Our study helps to illustrate the positive effect of Chinese herbal medicine on animal feeding and lay a foundation for the future rational application of Chinese herbal medicine in non-antibiotic feeding. Meanwhile, similar reports have not been found internationally. Conclusion Adding proper amount of Chinese herbal medicine in diet can promote the production of inosine acid and enhance the taste of meat, reduce the ash content similarly.

scholarly journals Chinese Herbal Medicine Bushen Qinggan Formula for Blood Pressure Variability and Endothelial Injury in Hypertensive Patients: A Randomized Controlled Pilot Clinical Trial

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Chunxiao Wu ◽  
Jingchun Zhang ◽  
Yingke Zhao ◽  
Jing Chen ◽  
Yue Liu
Keyword(s):  
Blood Pressure ◽  
Herbal Medicine ◽  
Endothelial Function ◽  
Chinese Herbal Medicine ◽  
Blood Pressure Variability ◽  
Endothelial Injury ◽  
Control Group ◽  
Therapeutic Effects ◽  
Chinese Herbal ◽  
Significant Difference

Background.Blood pressure variability (BPV) independent of average blood pressure is related to cardiovascular damage. Meanwhile, BPV is also associated with measures of endothelial injury. Decoction, a traditional used form of Traditional Chinese Medicine (TCM), is inconvenient to prepare, carry, and store. Dispensing granules is now developing as an alternative to decoction, but the evidence supporting its clinical efficacy the same as decoction remains unclear.Objective.To examine the therapeutic effects on mean blood pressure (MBP), blood pressure variability, and endothelial function by giving Bushen Qinggan Formula, a compound Chinese Herbal Medicine and also to evaluate the difference in efficacy between decoction and granule.Methods.A total of 150 patients with hypertension were enrolled and randomly assigned to receive the placebo, Bushen Qinggan decoction, or Bushen Qinggan granule in addition to the standard medications (amlodipine-5 mg/d) for the treatment of essential hypertension (EH). The outcome was the reduction in the MBP and BPV and also included changes in the endothelial markers including endothelin-1 (ET-1) and nitric oxide (NO) after 8 weeks of treatment.Results.Compared with the control group, the Bushen Qinggan decoction and granule groups had significant improvement (P<0.01) in BPV and endothelial founction. The level of BPV and endothelial function between decoction and granule group had no significant difference (P>0.05).Conclusion.Based on the standard treatment, Bushen Qinggan Formula further improved BPV and endothelial function. The efficacy of Bushen Qinggan decoction and granule is similar in improving BPV and endothelial function. However, no significant antihypertensive effects could be demonstrated.

scholarly journals Astragalus-Containing Chinese Herbal Medicine Combined With Chemotherapy for Cervical Cancer: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Lei Shen ◽  
Si Ra Gwak ◽  
Zhen Yang Cui ◽  
Jong Cheon Joo ◽  
Soo Jung Park
Keyword(s):  
Cervical Cancer ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Control Group ◽  
Karnofsky Performance Score ◽  
Medical Databases ◽  
Randomized Controlled ◽  
Chinese Herbal

Background: Cervical cancer is the fourth most common malignant tumor among women worldwide. This study aimed to evaluate the efficacy of Astragalus-containing Chinese herbal medicine (CHM) combined with chemotherapy (CT) for the treatment of cervical cancer.Methods: Ten electronic databases including PubMed, Cochrane Library, Embase, Korean databases, and Chinese medical databases, were systematically searched up to July 2020. All randomized controlled trials using Astragalus-containing CHM combined with CT to treat cervical cancer were included.Results: A total of 19 trials were included in the analysis. Compared with the control group, the Astragalus-containing CHM combined with CT group showed a significantly increased tumor response (complete and partial response (CR and PR)) (risk ratio [RR] = 1.25, 95% confidence interval [CI]: 1.17–1.33, p &lt; 0.00001) and Karnofsky performance score (KPS) (standardized mean difference [SMD] = 1.81, 95% CI: 1.46–2.17, p &lt; 0.00001). This group also displayed remarkably reduced CT toxicity.Conclusion: Our study suggests that Astragalus-containing CHM might be a potential option for cervical cancer to enhance the curative efficacy and reduce CT toxicity.

scholarly journals Changes of Endothelin-1 and Calcitonin Gene-Related Peptide Concentrations in Patients with Cervical Radiculopathy after Wrist-Ankle Acupuncture-Moxibustion and Hot Compression with Chinese Herbal Medicine

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Wei Li ◽  
Chi Yao ◽  
Yanghong Zhou ◽  
Sishi Chen
Keyword(s):  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Standard Treatment ◽  
Cervical Radiculopathy ◽  
Hot Compression ◽  
Control Group ◽  
Study Group ◽  
Endothelin 1 ◽  
Chinese Herbal ◽  
Calcitonin Gene

Objective. This study aimed at investigating the effects of wrist-ankle acupuncture-moxibustion and hot compression with Chinese herbal medicine on pain symptoms, endothelin-1 (ET-1), and calcitonin gene-related peptide (CGRP) concentrations of patients with cervical radiculopathy (CR). Methods. A total of 82 patients with CR were randomly divided into the study group and control group, with 41 cases in each group. The control group was treated with standard treatment. In addition to standard treatment, the study group was additionally treated with wrist-ankle acupuncture-moxibustion and hot compression with Chinese herbal medicine. The ET-1 and CGRP concentrations in the plasma were measured by the radioimmunoassay method. Results. The total response rate in the study group and the control group was 97.55% and 82.93%, respectively. The study group showed lower scores of the visual analogue scale (VAS), Northwick Park Neck Pain Questionnaire (NPQ), McGill Pain Questionnaire (MPQ), numbness intensity assessment, and neck disability index (NDI) but higher scores of the Short Form-36 (SF-36) health survey questionnaire than the control group after treatment. Besides, the study group exhibited reduced ET-1 and substance P (SP) concentrations concomitant with increased CGRP and β-endorphin (β-EP) concentrations compared with the control group. Conclusion. Wrist-ankle acupuncture-moxibustion and hot compression with Chinese herbal medicine could effectively alleviate the pain of CR patients, affect ET-1 and CGRP concentrations, promote the recovery of cervical function, and improve the quality of life.

scholarly journals Oral Chinese Herbal Medicine as an Adjuvant Treatment for Chemotherapy, or Radiotherapy, Induced Myelosuppression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2017 ◽  
Vol 2017 ◽  
pp. 1-13 ◽  
Author(s):  
Bonan Hou ◽  
Rui Liu ◽  
Zhen Qin ◽  
Dan Luo ◽  
Qi Wang ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Randomized Controlled Trials ◽  
Chinese Herbal Medicine ◽  
Common Side Effect ◽  
Hematological Toxicity ◽  
Control Group ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Chinese Herbal ◽  
Grade Iii

Objective. Myelosuppression is a common side effect in cancer patients receiving chemotherapy or radiotherapy. Chinese herbal medicine (CHM) has shown promise in alleviating myelosuppression. Method. We searched for randomized controlled trials (RCTs) from seven databases without language restriction. We included RCTs in adults, in which hematological toxicity was measured according to WHO criteria and control group underwent chemotherapy and/or radiotherapy and the treatment group was given oral CHM. Results. We searched 1021 articles from the date of databases inception to October 7, 2016. We selected 14 articles for the final analysis. Pooled data showed that CHM significantly decreased the suppression rate of leukocytes, neutrophils, hemoglobin, and platelets compared with the control group, particularly in grade III-IV toxicity (leukocytes: RR = 0.43, 95% CI = 0.33–0.56; neutrophils: RR = 0.39, 95% CI = 0.27–0.58; hemoglobin: RR = 0.33, 95% CI = 0.18–0.61; platelets: RR = 0.61, 95% CI = 0.39–0.95). Conclusions. CHM as an adjuvant can alleviate myelosuppression induced by chemotherapy or radiotherapy, reduce grade III-IV toxicity, and maintain therapeutic dose and treatment cycle. However, due to heterogeneity and publication bias, the results should be interpreted with caution and validated by conducting strictly designed multicenter RCTs of high quality and large scale.

scholarly journals Chinese Herbal Medicine Significantly Impacts the Haematological Variables of the Athlete Biological Passport

2021 ◽  
Vol 18 (18) ◽  
pp. 9533
Author(s):  
William Chih-Wei Chang ◽  
Chih-Yuan Wang ◽  
Wan-Yi Liu ◽  
Chin-Chuan Tsai ◽  
Yu-Tse Wu ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Statistical Significance ◽  
Blood Collection ◽  
Extrinsic Factors ◽  
Blood Profile ◽  
Chinese Herbal ◽  
Biological Passport ◽  
Profile Score ◽  
Sports Doping

In the fight against sports doping, the Athlete Biological Passport (ABP) system aims to indirectly unveil the doping incidents by monitoring selected biomarkers; however, several unexplored extrinsic factors may dampen a fair interpretation of ABP profiles. Chinese herbal medicine (CHM) plays a pivotal role in the health care system, and some remedies have a long history of being used to treat anaemia. In this study, we addressed the concerns of whether the CHM administration could yield a measurable effect on altering the ABP haematological variables. Forty-eight healthy volunteers were randomly assigned to receive two-week oral administration of one of the six selected CHM products that are commonly prescribed in Taiwan (eight subjects per group). Their blood variables were determined longitudinally in the phases of baseline, intervention, and recovery over 5 weeks. Blood collection and analyses were carried out in strict compliance with relevant operating guidelines. In the groups receiving Angelicae Sinensis Radix, Astragali Radix, and Salviae Miltiorrhizae Radix et Rhizoma, a significant increased reticulocyte percentage and decreased OFF-hr Score were manifested during the intervention, and such effects even sustained for a period of time after withdrawal. All other variables, including haemoglobin and Abnormal Blood Profile Score, did not generate statistical significance. Our results show that the use of CHM may impact the ABP haematological variables. As a consequence, we recommend athletes, particularly those who have been registered in the testing pool, should be aware of taking specific Chinese herbal-based treatment or supplementation, and document any of its usage on the anti-doping forms.

scholarly journals Treatment Efficacy of Chuang Ling Ye, a Traditional Chinese Herbal Medicine Compound, on Idiopathic Granulomatous Mastitis: A Randomized Controlled Trial

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Jing-xian Xue ◽  
Bei Ye ◽  
Shun Liu ◽  
Si-han Cao ◽  
Wei-he Bian ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Controlled Trial ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Granulomatous Mastitis ◽  
Idiopathic Granulomatous Mastitis ◽  
Traditional Chinese Herbal Medicine ◽  
Chinese Herbal ◽  
Dressing Change

Objective. To explore whether Chuang Ling Ye (CLY), a traditional Chinese herbal medicine compound, could improve the treatment of idiopathic granulomatous mastitis (IGM) via decreasing inflammatory response. Methods. Herein, 40 patients with IGM who had wounds requiring dressing change were enrolled and randomly divided into two groups: the CLY group and the control group. The size of the neoplasm and pain score of patients were followed-up for 4 weeks. Local tissues were taken during dressing change and examined by commercial enzyme-linked immunosorbent assay (ELISA) kits. The levels of inflammatory markers, including interleukin-1β (IL-1β), IL-2, IL-6, interferon gamma (IFN-γ), and tumor necrosis factor-α (TNF-α) were measured. Results. After treatment, the size of the neoplasm in the CLY group was significantly smaller than that in the control group (14.28 cm ± 8.96 cm vs. 21.14 cm ± 0.12 cm, P=0.038), and the pain scores were markedly reduced (P=0.004). Besides, CLY downregulated the expression levels of IL-1β, IFN-γ, and TNF-α. Conclusion. External use of CLY could reduce the neoplasm of IGM by inhibiting local inflammation. This trial is registered with ChiCTR1800017744.

Efficacy of quxie capsule in metastatic colorectal cancer: Update of a double-blind, randomized, placebo controlled trial.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e15030-e15030
Author(s):  
Tong Zhang ◽  
Wenting He ◽  
Yun Xu ◽  
Bin He ◽  
Yufei Yang
Keyword(s):  
Colorectal Cancer ◽  
Treatment Group ◽  
Herbal Medicine ◽  
Metastatic Colorectal Cancer ◽  
Chinese Herbal Medicine ◽  
Conventional Therapy ◽  
Controlled Trial ◽  
Control Group ◽  
Double Blind ◽  
Chinese Herbal

e15030 Background: To verify the efficacy of Quxie Capsule in patients with metastatic colorectal cancer (mCRC). Methods: This is a update of a randomized, double-blind, placebo-controlled trial. Between April 2014 and July 2015, 121 patients were enrolled in the study. Sixty patients were eligible and randomized to the two groups at a 1:1 ratio. Treatment group received conventional therapy and Chinese herbal medicine combined with Quxie Capsule for 3 months. Control group received conventional therapy and Chinese herbal medicine combined with placebo for 3 months. Main outcome measures were overall survival (OS) and progression-free survival (PFS). As of Dec 31st 2018, one patient in the control group was still alive, and all the other patients reached the main clinical endpoint. Median follow-up time was 19.4 months. Bo Ao Tong (Beijing) Medical Technology Co. Ltd. was responsible for the protocols of blind and block randomization. Results: The median OS were 23.9 months in the treatment group [95% confidence interval (CI) 15.9–28.5] vs. 14.3 months in the control group (95% CI 11.3–21.4) (Kaplan–Meier, Log-rank P=0.032), hazard ratio (95%CI)= 0.55 (0.31, 0.95), P=0.04. In the subgroups of left-sided colon, RAS wild type, non-targeted therapy, colon cancer and ≥second-line therapy, the median OS of the treatment group and the control group were respectively: 20.9 vs 12.2m, 17.4 vs 14.4m, 20.8 vs 12.0m, 25.1 vs 18.5m, 25.1 vs 12.0m ( P=0.037, 0.019, 0.022, 0.018, 0.007). There were no significant differences between the two groups in PFS. Conclusions: Quxie Capsule showed good efficacy, can reduce the risk of death and prolong the OS of patients with mCRC. Clinical trial information: ChiCTR-IOR-16009733.

Effect of Spirulina-Chinese herbal medicine on quality of eggs and serum biochemical indexes of egg-laying hens

2017 ◽  
Author(s):  
Liu Peipei ◽  
Zang Sumin
Keyword(s):  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Laying Hens ◽  
Egg Yolk ◽  
Egg Laying ◽  
Control Group ◽  
Egg Weight ◽  
Traditional Chinese Herbal Medicine ◽  
Chinese Herbal ◽  
Laying Performance

This study used three-factor linear regression orthogonal design to examine the impacts of traditional Chinese herbal medicine on egg quality and egg-laying hens’ biochemical indexes. 495 and 210d Hy-Line gray commercial egg-laying hens were selected and spirulina powder was added to their diet at 5 g/kg, 10g/kg, 15g/kg in the diet, rchmannia glutnosa polysaccharides were added at 2.5g/kg, 3 g/kg, 3.5 g/kg, and Leonurus Japonicas was added at 0.7 g/kg, 0.9g/kg, 1.1 g/kg. The hens were randomly allocated to a control group and ten test groups, in order to study the herbs’ effects on laying performance and immunity parameters. The results showed that: (1)When spirulina-Chinese herbal medicine was added, the average egg weight, yolk color, and Hartz unit increased significantly.(2) When spirulina powder levels were increased, the egg yolk color and iron content significantly increased while the cholesterol and triglyceride levels were significantly lower (P>0.05). With the increase of rchmannia glutnosa polysaccharides extracts, eggshell strength increased significantly (P>0.01). Egg yolk color and eggshell strength increased significantly (P>0.05 and P>0.01, respectively) when Leonurus Japonicas increased. (3) Spirulina powder and rchmannia glutnosa polysaccharides extracts were significantly antagonistic to average egg weight and eggshell strength (P>0.01). Leonurus Japonicus and rchmannia glutnosa polysaccharides were significantly antagonistic to eggshell strength and cholesterol levels (P>0.05).

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