Ageing, multimorbidity, and daily functioning

2017 ◽  
pp. 111-116
Author(s):  
Barbara Gryglewska ◽  
Karolina Piotrowicz ◽  
Tomasz Grodzicki
Keyword(s):  
Risk Factor ◽  
Chronic Disease ◽  
Functional Performance ◽  
Negative Impact ◽  
High Prevalence ◽  
Short And Long Term ◽  
Long Term Prognosis ◽  
Clinical Measures

Multimorbidity is defined as any combination of a chronic disease with at least one other acute or chronic disease or biopsychosocial or somatic risk factor. Old age is a leading risk factor for multimorbidity. It has a negative impact on short- and long-term prognosis, patients’ cognitive and functional performance, self-care, independence, and quality of life. It substantially influences patients’ clinical management and increases healthcare-related costs. There is a great variety of clinical measures to assess multimorbidity; some are presented in this chapter. Despite its high prevalence in older adults, clinical guidelines for physicians managing patients with multimorbidity are underdeveloped and insufficient.

Characterization of Sepsis and Sepsis-Associated Encephalopathy

2017 ◽  
Vol 34 (11-12) ◽  
pp. 938-945 ◽  
Author(s):  
Qing Feng ◽  
Yu-Hang Ai ◽  
Hua Gong ◽  
Long Wu ◽  
Mei-Lin Ai ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Risk Factor ◽  
Diagnostic Criteria ◽  
Mortality Rates ◽  
Apache Ii ◽  
Apache Ii Score ◽  
Long Term Prognosis

Background: Sepsis and sepsis-associated encephalopathy (SAE) are common intensive care unit (ICU) diseases; the morbidity and mortality are high. The present study analyzed the sensitivity of different diagnostic criteria of sepsis 1.0 and 3.0, epidemiological characteristics of sepsis and SAE, and explored its risk factors for death, short-term, and long-term prognosis. Methods: The retrospective study included patients in ICU from January 2015 to June 2016. After excluding 58 patients, 175 were assigned to either an SAE or a non-SAE group (patients with sepsis but no encephalopathy). The sensitivity of the diagnostic criteria was compared between sepsis 1.0 and 3.0, respectively. Between-group differences in baseline data, Acute Physiology and Chronic Health Evaluation II score (APACHE II score), Sequential Organ Failure Assessment score (SOFA score), etiological data, biochemical indicators, and 28-day and 180-day mortality rates were analyzed. Survival outcomes and long-term prognosis were observed, and risk factors for death were analyzed through 180-day follow-up. Results: The sensitivity did not differ significantly between the diagnostic criteria of sepsis 1.0 and 3.0 ( P = .286). The 42.3% incidence of SAE presented a significantly high APACHE II and SOFA scores as well as 28-day mortality and 180-day mortality (all P < .001). The incidence of death was 37.1%. The multivariate stepwise regression analysis demonstrated that the risk of death in SAE group was significantly higher than the non-SAE group ( P < .001). Sepsis-associated encephalopathy is a risk factor for sepsis-related death (relative risk [RR] = 2.868; 95% confidence interval: 1.730-4.754; P < .001). Although males showed a significantly high rate of 28-day and 180-day mortality ( P = .035 and .045), it was not an independent risk factor for sepsis-related death ( P = .072). The long-term prognosis of patients with sepsis was poor with decreased quality of life. No significant difference was observed in prognosis between the SAE and non-SAE groups ( P > .05). Conclusion: Both diagnostic criteria cause misdiagnosis, and the sensitivity did not differ significantly. The incidence of SAE was high, and 28-day and 180-day mortality rates were significantly higher than those without SAE. Sepsis-associated encephalopathy is a risk factor for poor outcome. The overall long-term prognosis of patients with sepsis was poor, and the quality of life decreased.

CHRONOBIOLOGICAL AND PSYCHOEMOTIONAL STATUS IN WOMEN WITH CHRONIC RECURRENT BACTERIAL CYSTITIS AND CARBOHYDRATE METABOLISM DISORDER

2020 ◽  
pp. 56-59
Author(s):  
Мария Николаевна Химичева ◽  
Андрей Владимирович Кузьменко ◽  
Владимир Васильевич Кузьменко ◽  
Тимур Асланбекович Гяургиев
Keyword(s):  
Chronic Disease ◽  
Carbohydrate Metabolism ◽  
Negative Impact ◽  
High Risk Group ◽  
Chronic Complications ◽  
Course Of Disease ◽  
Metabolism Disorder ◽  
Common Group ◽  
Tract Infections

Инфекции мочевых путей - наиболее распространённая группа заболеваний в практике врача уролога. Один из представителей является хронический рецидивирующий бактериальный цистит. Данное заболевание встречается во всех возрастных категориях и затрагивает все сферы жизни пациентов. Симптомы, возникающие при обострении хронического бактериального цистита, оказывают негативное влияние на качество жизни, что может приводить к нарушению психоэмоционального состояния больных. Отдельную группу высокого риска в отношении ИНМП составляют пациенты с нарушением углеводного обмена, у которых риск развития различных инфекций выше, чем у людей без подобных нарушений. К факторам, повышающим риск развития ИНМП у больных с нарушением углеводного обмена, относят возраст, компенсацию и наличие хронических осложнений, в первую очередь нефропатии и цистопатии. Человеческий организм функционирует циклически в соответствии с определенными индивидуальными ритмами. Любое хроническое заболевание приводит к рассогласованию процессов, протекающих в различных системах организма, вызывая развитие десинхроноза. Наличие у человека более 1 хронического заболевания утяжеляет течение болезни и приводит к снижению восстановительных способностей организма и сокращению его адаптационного потенциала Urinary tract Infections are the most common group of diseases in the practice of a urologist. One of the representatives is chronic recurrent bacterial cystitis. This disease occurs in all age categories and affects all areas of life of patients. Symptoms that occur with the exacerbation of chronic bacterial cystitis have a negative impact on the quality of life, which can lead to a violation of the psychoemotional state of patients. A separate high-risk group for INMP is patients with impaired carbohydrate metabolism, who have a higher risk of developing various infections than people without such disorders. Factors that increase the risk of developing INMP in patients with impaired carbohydrate metabolism include age, compensation, and the presence of chronic complications, primarily nephropathy and cystopathy. The human body functions cyclically in accordance with certain individual rhythms. Any chronic disease leads to misalignment of the processes occurring in various body systems, causing the development of DS, the Presence of more than 1 chronic disease complicates the course of disease and leads to a decrease in regenerative abilities of the organism and reduce its adaptive capacity

QUALITY OF LIFE PROBLEMS OF GYNECOLOGICAL CANCER PATIENTS

2017 ◽  
Vol 63 (3) ◽  
pp. 368-374
Author(s):  
Olga Churuksaeva ◽  
Larisa Kolomiets
Keyword(s):  
Quality Of Life ◽  
Gynecological Cancer ◽  
Social Aspects ◽  
Cancer Data ◽  
Life Problems ◽  
Anticancer Treatment ◽  
Short And Long Term ◽  
The Relationship

Due to improvements in short- and long-term clinical outcomes a study of quality of life is one of the most promising trends in oncology today. This review analyzes the published literature on problems dealing with quality of life of patients with gynecological cancer. Data on quality of life with respect to the extent of anticancer treatment as well as psychological and social aspects are presented. The relationship between quality of life and survival has been estimated.

Intra-pancreatic distal cholangiocarcinoma and pancreatic ductal adenocarcinoma: a common short and long-term prognosis?

2021 ◽  
Author(s):  
Théophile Guilbaud ◽  
Edouard Girard ◽  
Coralie Lemoine ◽  
Ghislain Schlienger ◽  
Oyekashopefoluw Alao ◽  
...  
Keyword(s):  
Pancreatic Ductal Adenocarcinoma ◽  
Ductal Adenocarcinoma ◽  
Distal Cholangiocarcinoma ◽  
Short And Long Term ◽  
Long Term Prognosis

scholarly journals Comparison of Short- and Long-Term Prognosis between ST-Elevation and Non-ST-Elevation Myocardial Infarction

2021 ◽  
Vol 10 (2) ◽  
pp. 180
Author(s):  
Frédéric Bouisset ◽  
Jean-Bernard Ruidavets ◽  
Jean Dallongeville ◽  
Marie Moitry ◽  
Michele Montaye ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Mortality Rate ◽  
Confounding Factors ◽  
Coronary Syndrome ◽  
Short And Long Term ◽  
St Elevation ◽  
Probability Of Death ◽  
Long Term Prognosis

Background: Available data comparing long-term prognosis according to the type of acute coronary syndrome (ACS) are scarce, contradictory, and outdated. Our aim was to compare short- and long-term mortality in ST-elevated (STEMI) and non-ST-elevated myocardial infarction (non-STEMI) ACS patients. Methods: Patients presenting with an inaugural ACS during the year 2006 and living in one of the three areas in France covered by the Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA) registry were included. Results: A total of 1822 patients with a first ACS—1121 (61.5%) STEMI and 701 (38.5%) non-STEMI—were included in the study. At the 28-day follow-up, the mortality rates were 6.7% and 4.7% (p = 0.09) for STEMI and non-STEMI patients, respectively, and after adjustment of potential confounding factors, the 28-day probability of death was significantly lower for non-STEMI ACS patients (Odds Ratio = 0.58 (0.36–0.94), p = 0.03). At the 10-year follow-up, the death rates were 19.6% and 22.8% (p = 0.11) for STEMI and non-STEMI patients, respectively, and after adjustment of potential confounding factors, the 10-year probability of death did not significantly differ between non-STEMI and STEMI events (OR = 1.07 (0.83–1.38), p = 0.59). Over the first year, the mortality rate was 7.2%; it then decreased and stabilized at 1.7% per year between the 2nd and 10th year following ACS. Conclusion: STEMI patients have a worse vital prognosis than non-STEMI patients within 28 days following ACS. However, at the 10-year follow-up, STEMI and non-STEMI patients have a similar vital prognosis. From the 2nd year onwards following the occurrence of a first ACS, the patients become stable coronary artery disease patients with an annual mortality rate in the 2% range, regardless of the type of ACS they initially present with.

scholarly journals Treatment and Prognosis of Myocardial Infarction Outside Cardiology Departments

2020 ◽  
Vol 10 (1) ◽  
pp. 106
Author(s):  
Anton Gard ◽  
Bertil Lindahl ◽  
Nermin Hadziosmanovic ◽  
Tomasz Baron
Keyword(s):  
Myocardial Infarction ◽  
Coronary Intervention ◽  
Cardiology Department ◽  
Percutaneous Coronary ◽  
All Cause Mortality ◽  
Short And Long Term ◽  
Long Term Prognosis ◽  
One Year

Aim: Our aim was to investigate the characteristics, treatment and prognosis of patients with myocardial infarction (MI) treated outside a cardiology department (CD), compared with MI patients treated at a CD. Methods: A cohort of 1310 patients diagnosed with MI at eight Swedish hospitals in 2011 were included in this observational study. Patients were followed regarding all-cause mortality until 2018. Results: A total of 235 patients, exclusively treated outside CDs, were identified. These patients had more non-cardiac comorbidities, were older (mean age 83.7 vs. 73.1 years) and had less often type 1 MIs (33.2% vs. 74.2%), in comparison with the CD patients. Advanced age and an absence of chest pain were the strongest predictors of non-CD care. Only 3.8% of non-CD patients were investigated with coronary angiography and they were also prescribed secondary preventive pharmacological treatments to a lesser degree, with only 32.3% having statin therapy at discharge. The all-cause mortality was higher in non-CD patients, also after adjustment for baseline parameters, both at 30 days (hazard ratio (HR) 2.28; 95% confidence interval (CI) 1.62–3.22), one year (HR 1.82; 95% CI 1.39–2.36) and five years (HR 1.62; 95% CI 1.32–1.98). Conclusions: MI treatment outside CDs is associated with an adverse short- and long-term prognosis. An improved use of percutaneous coronary intervention (PCI) and secondary preventive pharmacological treatment might improve the long-term prognosis in these patients.

Prevalence of Misconceptions about Diabetes and their Association with Metabolic and Psychological Variables

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Sergio Hernández-Jiménez
Keyword(s):  
Quality Of Life ◽  
Educational Level ◽  
Educational Assistance ◽  
Assistance Program ◽  
Psychological Variables ◽  
Lower Educational Level ◽  
High Prevalence ◽  
Short And Long Term ◽  
Glucose Management

Objective: To evaluate misconceptions about diabetes in people who attend the first visit at the CAIPaDi program, as well as its association with metabolic and psychological variables at short and long term. Methods and Analysis: The frequency of misconceptions in diabetes was determined through a true/false survey. We compared sociodemographic, metabolic and psychological variables between people with and without misconceptions at baseline, at 3 months and 1 year after a multidisciplinary educational program. Results: 902 participants answered the survey, with an age of 50 ±10 years old, 54.3% were women, with 1 (0-5) years living with type 2 diabetes. At baseline, 53% of the participants had at least 1 misconception, being more frequent in women (p=0.045) and in population with lower educational level (p<0.001). The most common were "emotional stress and fright cause diabetes" (34.4%), "in the control of my diabetes only matters glucose management" (15.2%) and "women with diabetes should not get pregnant" (11.8%). At basal, patients with misconceptions had higher HbA1c (9.0 ± 2.6 vs 8.4 ± 2.4, p <0.001), lower quality of life (DQOL 95.2 ± 26.2 vs 90.2 ± 23.6, p = 0.03), more problematic areas in diabetes (41.2 [21.2-58.4] vs 35 [17.5-52.6], p = 0.01), more depression (42.6% vs 32.9%, p = 0.003) and anxiety (58.6% vs 40.6%, p = 0.001) compared to patients without misconceptions. With the exception of HbA1c (6.6 ± 1 vs 6.4 ± 0.8, p = 0.025 at 1 year), no differences were observed in the annual visits. Conclusion: We found a high prevalence of people with misconceptions in diabetes. This group had worst glycaemic control, higher scores in PAID questionnaire, lower quality of life and more depression and anxiety symptoms. Participants with misconceptions had lower educational level. An educative program an educational assistance program can minimize differences by eradicating misconceptions.

Quality of life and patient-centered outcomes following atrial fibrillation ablation: short- and long-term perspectives to improving care

2012 ◽  
Vol 10 (7) ◽  
pp. 889-900 ◽  
Author(s):  
Sanghamitra Mohanty ◽  
Luigi Di Biase ◽  
Rong Bai ◽  
Pasquale Santangeli ◽  
Agnes Pump ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Atrial Fibrillation ◽  
Atrial Fibrillation Ablation ◽  
Patient Centered ◽  
Short And Long Term
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