Other statistical methods

2020 ◽  
pp. 405-438
Author(s):  
Janet L. Peacock ◽  
Philip J. Peacock
Keyword(s):  
Missing Data ◽  
Medical Research ◽  
Statistical Methods ◽  
Life Tables ◽  
The Other ◽  
Cost Data ◽  
Number Needed To Treat

This chapter describes several individual statistical methods that do not fit neatly in the other chapters but which are commonly used in medical research. These include methods used to assess agreement in measurement and reliability studies, the number needed to treat as a measure of efficacy in a trial, life tables, missing data, and analysing cost data. All methods are illustrated with examples.

Other statistical methods

2010 ◽  
pp. 353-375
Author(s):  
Janet L. Peacock ◽  
Philip J. Peacock
Keyword(s):  
Statistical Methods ◽  
Goodness Of Fit ◽  
Life Tables ◽  
Number Needed To Treat ◽  
Rater Agreement ◽  
Goodness Of Fit Test ◽  
Bland Altman Method ◽  
Chi Squared ◽  
Indirect Standardization ◽  
Direct Standardization

Kappa for inter-rater agreement 354 Extensions to kappa 358 Bland–Altman method to measure agreement 360 Chi-squared goodness of fit test 364 Number needed to treat 366 Life tables 370 Direct standardization 372 Indirect standardization 374 In this chapter we describe several individual statistical methods that do not fit neatly in the other chapters but which are commonly used in medical research. These include methods used to assess agreement in measurement and reliability studies, the number needed to treat as a measure of efficacy in a trial, and life tables. All methods are illustrated with examples....

scholarly journals Is the secrecy of the parametric configuration of slot machines rationally justified? The exposure of the mathematical facts of games of chance as an ethical obligation

2014 ◽  
pp. 1 ◽  
Author(s):  
Cătălin Bărboianu
Keyword(s):  
Missing Data ◽  
Statistical Methods ◽  
The Other ◽  
Slot Machines ◽  
Ethical Obligation ◽  
Rational Justification ◽  
Specific Element ◽  
Games Of Chance

Slot machines have gained high popularity despite a specific element that could limit their appeal: non-transparency with respect to mathematical parameters. The PAR sheets, which expose the parameters of the design of slot machines and probabilities associated with the winning combinations, are kept secret by game producers, and the lack of data regarding the configuration of a machine prevents people from computing probabilities and other mathematical indicators. In this article, I argue that there is no rational justification for this secrecy for two reasons: one psychological and the other mathematical. For the latter, I show that mathematics provides us with some statistical methods of retrieving the missing data, which are essential for numerical probability computations in slots. The slots case described herein raises the problem of exposing the parametric configuration and mathematical facts of any game of chance as an ethical obligation.

Missing Data in Research on Youth and Family Programs

2021 ◽  
pp. 003329412110268
Author(s):  
Jaime Ballard ◽  
Adeya Richmond ◽  
Suzanne van den Hoogenhof ◽  
Lynne Borden ◽  
Daniel Francis Perkins
Keyword(s):  
Missing Data ◽  
Statistical Methods ◽  
Self Report ◽  
Program Participation ◽  
Multilevel Data ◽  
Individual Level ◽  
Level Data ◽  
Before And After ◽  
Post Test ◽  
The Individual

Background Multilevel data can be missing at the individual level or at a nested level, such as family, classroom, or program site. Increased knowledge of higher-level missing data is necessary to develop evaluation design and statistical methods to address it. Methods Participants included 9,514 individuals participating in 47 youth and family programs nationwide who completed multiple self-report measures before and after program participation. Data were marked as missing or not missing at the item, scale, and wave levels for both individuals and program sites. Results Site-level missing data represented a substantial portion of missing data, ranging from 0–46% of missing data at pre-test and 35–71% of missing data at post-test. Youth were the most likely to be missing data, although site-level data did not differ by the age of participants served. In this dataset youth had the most surveys to complete, so their missing data could be due to survey fatigue. Conclusions Much of the missing data for individuals can be explained by the site not administering those questions or scales. These results suggest a need for statistical methods that account for site-level missing data, and for research design methods to reduce the prevalence of site-level missing data or reduce its impact. Researchers can generate buy-in with sites during the community collaboration stage, assessing problematic items for revision or removal and need for ongoing site support, particularly at post-test. We recommend that researchers conducting multilevel data report the amount and mechanism of missing data at each level.

Most Often Motivated by Social Media: The Who, the What, and the How Much—Experience from Poland

2021 ◽  
Vol 13 (20) ◽  
pp. 11193
Author(s):  
Karol Król ◽  
Dariusz Zdonek
Keyword(s):  
Social Media ◽  
Intrinsic Motivation ◽  
Statistical Methods ◽  
The Other ◽  
Public Expression ◽  
Other Hand ◽  
The Impact ◽  
The Way

Content published in social media (SM) can be motivating. It can induce action, stimulate demand, and shape opinions. On the other hand, it can demotivate, cause helplessness, or overwhelm with information. Still, the impact of SM is not always the same. The paper aims to analyse the relations between sex, personality, and the way social media is used and motivation to take specific actions. The conclusions are founded on a survey (n = 462). The data were analysed with statistical methods. The study revealed that the use of SM has a significant impact on the motivation to act. Browsing through descriptions and photographs of various achievements posted by others in SM increased the intrinsic motivation of the respondents. Positive comments and emojis had a similar effect. Moreover, women and extraverts noted a significantly greater impact of SM on their intrinsic motivation concerning health and beauty effort, travel, hobby, and public expression of opinions than men and introverts. The results can be useful to recruiters. Extravert women that are open to cooperation, thorough, and well-organised are more likely to be active in SM.

scholarly journals Cost-Effectiveness Analysis of Biopharmaceuticals for Treating Rheumatoid Arthritis: Infliximab, Adalimumab, and Etanercept

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Ahmad Gholami ◽  
Jassem Azizpoor ◽  
Elham Aflaki ◽  
Mehdi Rezaee ◽  
Khosro Keshavarz
Keyword(s):  
Rheumatoid Arthritis ◽  
Sensitivity Analysis ◽  
Cost Effectiveness ◽  
Cost Effective ◽  
The Other ◽  
Cost Data ◽  
Fars Province ◽  
Study Results ◽  
The Mean ◽  
The Cost

Introduction. Rheumatoid arthritis (RA) is a chronic progressive inflammatory disease that causes joint destruction. The condition imposes a significant economic burden on patients and societies. The present study is aimed at evaluating the cost-effectiveness of Infliximab, Adalimumab, and Etanercept in treating rheumatoid arthritis in Iran. Methods. This is a cost-effectiveness study of economic evaluation in which the Markov model was used. The study was carried out on 154 patients with rheumatoid arthritis in Fars province taking Infliximab, Adalimumab, and Etanercept. The patients were selected through sampling. In this study, the cost data were collected from a community perspective, and the outcomes were the mean reductions in DAS-28 and QALY. The cost data collection form and the EQ-5D questionnaire were also used to collect the required data. The results were presented in the form of an incremental cost-effectiveness ratio, and the sensitivity analysis was used to measure the robustness of the study results. The TreeAge Pro and Excel softwares were used to analyze the collected data. Results. The results showed that the mean costs and the QALY rates in the Infliximab, Adalimumab, and Etanercept arms were $ 79,518.33 and 12.34, $ 91,695.59 and 13.25, and $ 87,440.92 and 11.79, respectively. The one-way sensitivity analysis confirmed the robustness of the results. In addition, the results of the probabilistic sensitivity analysis (PSA) indicated that on the cost-effectiveness acceptability curve, Infliximab was in the acceptance area and below the threshold in 77% of simulations. The scatter plot was in the mentioned area in 81% and 91% of simulations compared with Adalimumab and Etanercept, respectively, implying lower costs and higher effectiveness than the other two alternatives. Therefore, the strategy was more cost-effective. Conclusion. According to the results of this study, Infliximab was more cost-effective than the other two medications. Therefore, it is recommended that physicians use this medication as the priority in treating rheumatoid arthritis. It is also suggested that health policymakers consider the present study results in preparing treatment guidelines for RA.

European Coal and Steel Community

1955 ◽  
Vol 9 (4) ◽  
pp. 595-596
Keyword(s):  
Medical Research ◽  
The Other ◽  
Living Standard ◽  
Association Agreement ◽  
Housing Projects ◽  
The Third ◽  
The United Kingdom ◽  
The Common ◽  
Foreign Ministers ◽  
Opening Address

Common AssemblyThe third ordinary session of the Common Assembly of the European Coal and Steel Community (ECSC) reconvened from June 21 to 24, 1955. In his opening address Mr. Rene Mayer, newly elected president of the High Authority of the ECSC, expressed general agreement with the policy resolutions passed by the Common Assembly at its May meeting, and specifically mentioned resolutions on cartels, on implementation of the association agreement with the United Kingdom, and on action to improve the living standard of the workers in the ECSC countries, in regard to which he announced that the High Authority would shortly conclude two loans to finance new workers' housing projects–one of $4,000,000 in Belgium and the other of just over $4,000,000 in Germany. In addition, $300,000 were to be allocated for medical research. In commenting on the Messina conference of foreign ministers, Mr. Mayer said that the High Authority welcomed the decision to explore means of extending the single market. At the same time, he warned the Assembly to expect resistance to changes as the Community developed.

scholarly journals Missing Data in Randomized Clinical Trials for Weight Loss: Scope of the Problem, State of the Field, and Performance of Statistical Methods

PLoS ONE ◽  
2009 ◽  
Vol 4 (8) ◽  
pp. e6624 ◽  
Author(s):  
Mai A. Elobeid ◽  
Miguel A. Padilla ◽  
Theresa McVie ◽  
Olivia Thomas ◽  
David W. Brock ◽  
...  
Keyword(s):  
Weight Loss ◽  
Clinical Trials ◽  
Missing Data ◽  
Statistical Methods ◽  
Randomized Clinical Trials ◽  
And Performance ◽  
State Of The Field
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