Impact of the Turning-Against-Self Defense Mechanism on the Process and Outcome of Inpatient Psychotherapy

2003 ◽  
Vol 13 (3) ◽  
pp. 355-370 ◽  
Author(s):  
F. Geiser
Keyword(s):  
Defense Mechanism ◽  
Inpatient Psychotherapy ◽  
Self Defense ◽  
Process And Outcome

Age-specific different immune responses due to capabilities of secreting primal immunoglobulins responding to unexperienced antigens

2021 ◽  
Author(s):  
JANGHO LEE ◽  
Kyoungshik Cho ◽  
Hyejin Kook ◽  
Suman Kang ◽  
Yunsung Lee ◽  
...  
Keyword(s):  
Stem Cells ◽  
Immune System ◽  
Defense Mechanism ◽  
Ex Vivo ◽  
Binding Capacity ◽  
Culture Conditions ◽  
Fetal Stem Cells ◽  
Self Defense ◽  
Wide Range ◽  
Ex Vivo Culture

Abstract Among numerous studies on COVID-19, we noted that the infection and mortality rates of SARS-CoV-2 increased with age and that fetuses known to be particularly susceptible to infection were better protected despite various mutations. Hence, we established the hypothesis that a new immune system exists that forms before birth and decreases with aging. To prove this, we analyzed the components from early pregnancy fetal stem cells cultivated in various ex-vivo culture conditions simulating the environment during pregnancy. Resultingly, we confirmed that IgM, a natural antibody produced only in early B-1 cells, immunoglobulins including IgG3, which has a wide range of antigen-binding capacity and affinity, complement proteins, and antiviral proteins are induced. Our results suggest that fetal stem cells can form an independent immune system responding to unlearned antigens as a self-defense mechanism before establishing mature immune systems. Moreover, we propose the possibility of new solutions to cope with various infectious diseases based on the factors therein.

A Generalized and Robust Anti-Predatory Nature-Inspired Algorithm for Complex Problems

2019 ◽  
Vol 10 (1) ◽  
pp. 75-91 ◽  
Author(s):  
Rohit Kumar Sachan ◽  
Dharmender Singh Kushwaha
Keyword(s):  
Standard Deviation ◽  
Defense Mechanism ◽  
Mathematical Formulation ◽  
Predatory Behavior ◽  
Rank Test ◽  
Bee Colony ◽  
Self Defense ◽  
Nature Inspired Algorithm ◽  
Nature Inspired Algorithms ◽  
Result Analysis

This article describes how nature-inspired algorithms (NIAs) have evolved as efficient approaches for addressing the complexities inherent in the optimization of real-world applications. These algorithms are designed to imitate processes in nature that provide some ways of problem solving. Although various nature-inspired algorithms have been proposed by various researchers in the past, a robust and computationally simple NIA is still missing. A novel nature-inspired algorithm that adapts to the anti-predatory behavior of the frog is proposed. The algorithm mimics the self defense mechanism of a frog. Frogs use their reflexes as a means of protecting themselves from the predators. A mathematical formulation of these reflexes forms the core of the proposed approach. The robustness of the proposed algorithm is verified through performance evaluation on sixteen different unconstrained mathematical benchmark functions based on best and worst values as well as mean and standard deviation of the computed results. These functions are representative of different properties and characteristics of the problem domain. The strength and robustness of the proposed algorithm is established through a comparative result analysis with six well-known optimization algorithms, namely: genetic, particle swarm, differential evolution, artificial bee colony, teacher learning and Jaya. The Friedman rank test and the Holm-Sidak test have been used for statistical analysis of obtained results. The proposed algorithm ranks first in the case of mean result and scores second rank in the case of “standard deviation”. This proves the significance of the proposed algorithm.

scholarly journals Self-Destructive Behavior Analysis of Hannah Baker in The Thirteen Reasons Why Novel

2020 ◽  
Vol 1 (2) ◽  
pp. 16-32
Author(s):  
Jeantriani Febrita ◽  
Eka Margianti Sagimin
Keyword(s):  
Sigmund Freud ◽  
Defense Mechanisms ◽  
Defense Mechanism ◽  
Qualitative Approach ◽  
The Self ◽  
The Novel ◽  
Main Character ◽  
Destructive Behavior ◽  
The Past ◽  
Self Defense

This study investigates Self-Destructive Behavior of Hannah Baker in Thirteen Reasons Why novel, conducted in qualitative approach analysis of self-destructive behavior of the main character and what reasons or the causes of it through the narratives in the Thirteen Reasons Why novel. The goal of the study is to analyze how self-destructive behavior impacted the main character, Hannah Baker which is described using the theory of Self-Destructive Behavior and Defense Mechanisms by Sigmund Freud (1966). The result of this study shows that Hannah Baker developed the self-destructive behavior as a defense mechanisms from herself that triggered by trauma from the past. It started with the non-suicidal self-destructive behavior but soon turns into the suicidal self-destructive behavior. This study also shows how a suicide can really be an impact of the behavior that happens in the novel resulted from a non-suicidal self-destructive behavior that is not handled well, and all the mistreatments that the main character felt which produce the desire for ending her life.Keywords: Self-Defense Mechanism, Self-Destructive Behavior, Sigmund Freud, Suicide, Thirteen Reasons Why.

scholarly journals Eradicate Coronavirus by blocking replication, counteracting its defense system

2020 ◽  
Author(s):  
Kira Smith
Keyword(s):  
Target Genes ◽  
Defense Mechanism ◽  
P53 Protein ◽  
Sirtuin 1 ◽  
Defense System ◽  
Virus Growth ◽  
Self Defense ◽  
System P ◽  
Lysosomotropic Agent ◽  
Regulation Of Growth

SIRT1 inhibitors can reduce replication of many viruses with certain similar characteristics to those of Coronaviruses, while p53 protein is another important factor in down-regulation of growth. There are some molecules that inhibit Sirtuin 1 and 2, in addition to activate p53 protein, by means of regulation of the interactions used by Coronaviruses as self-defense mechanism, degradating it. Even mTOR signal will be regulate, as well as HIF-1α with the target genes and cytokines. Autophagy will be inhibited, being this compound like a lysosomotropic agent. By blocking virus growth and continuous replication, associating the already tested Antiviral medicines, Covid-19 could be eradicated.

scholarly journals Coxiella burnetii-Infected NK Cells Release Infectious Bacteria by Degranulation

2020 ◽  
Vol 88 (11) ◽  
Author(s):  
Svea Matthiesen ◽  
Luca Zaeck ◽  
Kati Franzke ◽  
Rico Jahnke ◽  
Charlie Fricke ◽  
...  
Keyword(s):  
Nk Cells ◽  
Coxiella Burnetii ◽  
Defense Mechanism ◽  
Cell Types ◽  
Chlamydia Psittaci ◽  
Content Type ◽  
Lytic Granules ◽  
Self Defense ◽  
Different Types ◽  
Ifn Γ

ABSTRACT Natural killer (NK) cells are critically involved in the early immune response against various intracellular pathogens, including Coxiella burnetii and Chlamydia psittaci. Chlamydia-infected NK cells functionally mature, induce cellular immunity, and protect themselves by killing the bacteria in secreted granules. Here, we report that infected NK cells do not allow intracellular multiday growth of Coxiella, as is usually observed in other host cell types. C. burnetii-infected NK cells display maturation and gamma interferon (IFN-γ) secretion, as well as the release of Coxiella-containing lytic granules. Thus, NK cells possess a potent program to restrain and expel different types of invading bacteria via degranulation. Strikingly, though, in contrast to Chlamydia, expulsed Coxiella organisms largely retain their infectivity and, hence, escape the cell-autonomous self-defense mechanism in NK cells.

English Title A study on the Effects of Self-Defense Mechanism on the SNS Addition

2020 ◽  
Vol 16 (4) ◽  
pp. 53-66
Author(s):  
Pyung-Sic Kim ◽  
Hyun-Joo Shin
Keyword(s):  
Defense Mechanism ◽  
Self Defense
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