P017 Complications of Juvenile Idiopathic Arthritis

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_5) ◽  
Author(s):  
S Miladi ◽  
S Bouzid ◽  
A Fazaa ◽  
L Souabni ◽  
M Sellami ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Adverse Effects ◽  
Disease Onset ◽  
Clinical Signs ◽  
Membranous Glomerulonephritis ◽  
Cross Sectional Study ◽  
Chronic Inflammatory Disease ◽  
Cross Sectional ◽  
Renal Manifestation ◽  
The Mean

Abstract Background Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease characterized by onset before the age of 16. This term encompasses several disease categories, each of which has distinct methods of presentation, clinical signs, and prognosis. The study aimed to determine JIA complications in 51 patients. Methods A cross-sectional study including patients diagnosed with JIA according to ILAR criteria was conducted for 26 years [1995– 2021]. Epidemiological, clinical, therapeutic, and evolutive aspects were noted. Results Twenty-nine males and 22 females were included. The mean age of the disease onset was 7.6 years [1,5–16]. The mean age of patients at the time of the study was 23.29 years [9–45]. Polyarticular and seronegative form was the most frequent (34.5%). Other subtypes diagnosed were systemic (25%), enthesitis-related arthritis (21.2%), oligoarticular (12.5%), and seropositive polyarticular (5.8%). Standard X-Ray imaging showed articular damage in 50% of the cases. Hip arthritis was observed in 32% and surgery was needed in 16.9%. One patient presented with atlantoaxial subluxation. Growth retardation was noted in 28.6%. Cardiac manifestations were seen in 3 patients (pericarditis = 2, myocarditis = 1), uveitis in 3 cases, renal manifestation (extra membranous glomerulonephritis) in one patient with polyarticular form. One patient was diagnosed with multiple sclerosis. Small doses of corticosteroids were prescribed in 71.7%. Methotrexate was prescribed in 70.5% (interrupted for adverse effects in 3 patients), sulfasalazine in 30.6%, hydroxychloroquine in 5.7%, leflunomide in 15.4%. bDMARDs were needed in 16 patients: 14 patients received TNF alpha inhibitors, rituximab was prescribed for one patient with a polyarticular form, and tocilizumab in a patient with a systemic form. A switch of bDMARDs was conducted in 10 patients: for inefficiency in 4 cases and adverse effects in other 4 cases. Three patients developed uveitis under Etanercept, septicemia under Adalimumab, an allergic reaction, and depression under Infliximab. One patient died from a convulsive seizure at the age of 9. Conclusion The presence of complications is an additional burden to JIA patients. A multidisciplinary approach is required for the management of these complications.

P019 Adulthood of juvenile idiopathic arthritis patients: professional outcome

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_5) ◽  
Author(s):  
S Miladi ◽  
S Bouzid ◽  
A Fazaa ◽  
L Souabni ◽  
M Sellami ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
College Graduates ◽  
Disease Onset ◽  
Cross Sectional Study ◽  
Full Time ◽  
Family Status ◽  
Cross Sectional ◽  
Telephone Interviews ◽  
The Mean ◽  
Professional Outcome

Abstract Background Juvenile idiopathic arthritis (JIA) is a heterogeneous group of rheumatic diseases characterized by onset before the age of 16. Since the disease starts at an early age, it may lead to socio-professional difficulties in adulthood for JIA patients. This study aimed to describe the professional outcome of a series of 20 JIA patients. Methods A cross-sectional study including patients aged 20 years and more and fulfilling the ILAR criteria for the diagnosis of JIA was carried out. Telephone interviews were conducted. The responders answered questions about family status, current occupation, working h, eventual workplace adjustments, and sick leave frequency. Results Twenty patients answered the questionary; 14 males and 6 females. The mean age of the disease onset was 8 years. The mean age of patients at the time of the study was 24.27 years [20–36]. Polyarticular form was the most frequent (10 cases). Other subtypes diagnosed were systemic (4 cases), enthesitis-related arthritis (5 cases), oligoarticular (one case). Hip arthritis was observed in 8 patients and surgical intervention was needed in three. Eight patients were treated with csDMARDSs and 12 with bDMARDs. Three of our patients were married (aged 24, 34, and 36). Five were still studying: 4 had good grades without absenteeism. However, one patient needed special aid to go to school and had a higher absence rate. Five other patients were full-time college students without absenteeism. Four patients were college graduates. Among them, two were searching for a job for >6 months. The other two were full-time administrative workers with no absenteeism. One patient did need workplace adjustments. Six patients could not work because of their physical disabilities. Conclusion According to our results, a quarter of our patients could not access professional life. Disease activity and hip destruction are the two main factors causing JIA patients to miss out on important personal and professional opportunities.

P031 Adherence with Methotrexate in Tunisian Juvenile Idiopathic Arthritis Patients

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_5) ◽  
Author(s):  
Hiba Bettaieb ◽  
Wafa Triki ◽  
Kaouther Maatallah ◽  
Hanene Ferjani ◽  
Dorra Ben Nessib ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Rheumatoid Factor ◽  
Disease Duration ◽  
Pediatric Population ◽  
Demographic Data ◽  
Disease Onset ◽  
Weekly Dose ◽  
Cross Sectional ◽  
High Adherence ◽  
The Mean

Abstract Background Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in the pediatric population. Methotrexate (MTX) has been considered as the cornerstone of treatment of poly and oligoarticular subtypes of JIA. However, this treatment is supposed to be for long term, which may involve an obstacle for adherence. The aims of the study were to evaluate adherence of Tunisian JIA patients to MTX and to identify factors associated with high adherence to MTX. Methods A cross-sectional study including patients with confirmed JIA diagnosis, according to the International League of Associations for Rheumatology (ILAR) criteria, was performed. Demographic data as well as disease characteristics were obtained from medical records. Laboratory markers including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were collected. Adherence was measured, for patients under MTX for >3 months, using the 5-item Compliance Questionnaire Rheumatology (CQR5) (1). Patients were divided into two groups: group 1: High adherence (HA) for patients having a CQR5 ≥ 80% and group 2: low adherence (LA) for patients having CQR5 < 80%. A p inferior to 0.05 was considered statistically significant. Results The study included 29 patients (10 males and 19 females) with a mean age at disease onset of 9.1 ± 3.4 years. The mean disease duration was 61 ± 79 months [7–336]. JIA subtypes were in decreasing order of frequency as follows: enthesitis-related arthritis (n = 13), oligoarticular (n = 8), Polyarticular without rheumatoid factor (n = 4), Polyarticular with rheumatoid factor (n = 2), systemic (n = 1) and, psoriatic arthritis (n = 1). A biologic inflammatory syndrome was found in 48.3% (n = 14) of cases. The mean ESR and CRP were 20 mm/h ± 11.3 [3–98] and 5 ± 17.8 mg/l [0–56] respectively. Nineteen (65.5%) patients had coxitis. Overall, 55.17% of patients (n = 16) were treated with MTX with a mean weekly dose of 9.2 ± 3.2 mg [5–15]. MTX was orally administrated in all patients. NSAIDs and prednisone were prescribed in 51.7% (n = 15) and 17.2% (n = 5) of cases respectively. The MTX was associated with biological DMARDs in five patients (17.2%). It was about Etanercept in 4 patients and Tocilizumab in 1 patient. Mean CQR5 score was 70.8% ± 18 [25–100]. Only seven patients (43.8%) showed high adherence to MTX. The statistical study revealed no difference between HA and LA in term of gender (P = 0.84), age at disease onset (P = 0.39), disease duration (P = 0.9), prednisone use (P = 0.22), the occurrence of coxitis (P = 0.2), ESR (P = 0.83) and CRP (P = 0.033) rates. Conclusion In this study, less than one half of JIA patients were highly adherent to MTX according to CQR5. Low adherence should be considered before declaring MTX treatment failure.

scholarly journals Sociodemographic Impact and Acquaintance on Antibiotic Resistance Among Outpatients in Specialist Hospital, Malaysia

2021 ◽  
Vol 20 (3) ◽  
Author(s):  
Hanish Singh Jayasingh Chellammal ◽  
Mohamed Mansor Manan ◽  
Thayashini Kupusamy ◽  
Long Chiau Ming ◽  
Shafeeq Mohd Faizal
Keyword(s):  
Antimicrobial Resistance ◽  
Adverse Effects ◽  
Cross Sectional Study ◽  
Antibiotics Resistance ◽  
Cross Sectional ◽  
Global Issues ◽  
Validated Questionnaire ◽  
Significant Difference ◽  
The Mean ◽  
Knowledge And Attitude

INTRODUCTION: Awareness on antibiotics resistance among outpatients in hospital settings is reasonably explored and this study aimed to investigate the sociodemographic impact and the level of acquaintance towards antibiotics practice and resistance. MATERIALS AND METHODS: This cross-sectional study was conducted on 270 patients from the outpatient department of KPJ Seremban Specialist Hospital (KPJSSH), Malaysia. A pre-validated questionnaire was used to collect the data on the demographics of the patients, their knowledge, attitude, and usage of antibiotics. The study was approved by the KPJUC ethics committee (KPJUC/RMC/BPH/EC/2017/104). RESULTS: The mean age of the respondents was 36 ± 11.07 years and 50.37% of them have moderate knowledge on antibiotics. The knowledge and attitude on antibiotics usage exhibited a significant difference (p=0.001) amongst these patients in association with literacy. The results showed that the literate respondents have significant knowledge on the identification of antibiotics (p=0.021), their roles, and adverse effects (p=0.004). The attitude of the respondents towards following the prescription was significantly associated with their literacy (p=0.004). CONCLUSION: This study reveals that respondents have the least knowledge on antibiotic course compliance and termination of therapy, which could lead to antimicrobial resistance. In conclusion, inculcating the knowledge of antimicrobial resistance, adverse effects, and course compliance among the patients may help overcome the national and global issues on multi-drug-resistant diseases.

scholarly journals Clinical and radiological characteristics of brain abscess caused by Streptococcus species: a cross-sectional study

2020 ◽  
Author(s):  
Jiachun Su ◽  
Bin Hu ◽  
Yixin Zhang ◽  
Ying Li
Keyword(s):  
Brain Abscess ◽  
Clinical Signs ◽  
Cross Sectional Study ◽  
Antimicrobial Treatment ◽  
Thick Wall ◽  
Limb Weakness ◽  
Cross Sectional ◽  
Streptococcus Species ◽  
Radiological Features ◽  
The Mean

Abstract Background: Streptococcus species are mostly reported the predominant organisms causing brain abscess (BA), however, there is no article focusing on the characteristics of patients with BA caused by Streptococcus species to date. This study aimed to describe the clinical and radiological features of patients with BA caused by Streptococcus species. Methods: All patients who were hospitalized due to BA with intracranial pus culture result of Streptococcus species alone after neurosurgical intervention from May 2015 to August 2018 in Huashan Hospital in Shanghai were included in this study. The data of patient demographics, clinical and radiological presenting features, microbiological results, surgical and antimicrobial treatment, and outcomes were collected. Results: Thirteen patients (10 male, 3 female) of primary brain abscesses were involved. The most frequent clinical presentations included headache (76.9%), fever (38.5%) and limb weakness (38.5%).The radiological features of abscesses in these patients included singularity, big size, thick wall and obvious oedema. The average abscess diameter before surgery was 51.62±11.00mm. The mean thickness of abscesses wall was 5.23±1.78mm. The mean range of oedema and distance between abscess margin were 93.62±16.31mm, 26.38±8.03mm, respectively. The strains isolated in this study all belonged to the viridans group and showed high susceptibility to cefotaxime and levofloxacin. All patients had good outcomes at discharge. Conclusion: Patients with BAs caused by Streptococcus species had unspecific clinical signs, but specific radiological features, which might be helpful for early diagnosis.

scholarly journals Celiac Disease and Non-celiac Gluten Sensitivity Screening in Juvenile Idiopathic Arthritis Patients

2020 ◽  
Author(s):  
Günsel Kutluk ◽  
Hafize Emine Sönmez ◽  
Hülya Kaçmaz
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Celiac Disease ◽  
Tissue Transglutaminase ◽  
Cross Sectional Study ◽  
Gluten Sensitivity ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
The Mean ◽  
Autoimmune Etiology ◽  
Endomysium Antibody

INTRODUCTION: Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children characterized by autoimmune etiology. In previous studies, increased Celiac disease (CD) frequency was reported in patients diagnosed with JIA. In this study, CD and non-celiac gluten sensitivity (NCGS) in patients diagnosed with JIA were investigated. METHODS: Sixty-one (57.3%) JIA patients admitted to the pediatric rheumatology outpatient clinic between January 2020 and April 2020 were included in this cross-sectional study. All patients were evaluated with clinical and laboratory findings in terms of CD and NCGS. Total immunoglobulin (Ig)-A, tissue transglutaminase antibody (tTG) IgA and IgG, anti-endomysium-antibody (EMA) IgA and IgG and anti-gliadin-antibody (AGA) IgA and IgG levels were measured in all patients. RESULTS: Sixty-one JIA patients, 35 girls, were included in the study. The mean age of the patients was 11.4 ± 4.6 years, the mean age at diagnosis is 10.2 ± 3.4 years. Thirty-three patients were diagnosed with oligoarticular JIA; 18 patients with enthesitis-related arthritis, 8 patients with polyarticular JIA, and 2 patients with psoriatic arthritis. All patients were using disease-modifying antirheumatic drugs during the study. Thirty-five patients were receiving biological therapy, concomitantly. Two patients had abdominal pain, two patients had indigestion, and two patients had constipation. None of the patients had growth retardation. EMA IgA and IgG, tTG IgA and IgG, AGA IgA and IgG tests were negative in all patients. DISCUSSION AND CONCLUSION: CD and NCGS were not detected in our JIA patients. Multi-center studies may guide clinicians in under what circumstances to perform CD and NCGS screening in JIA patients.

scholarly journals Correlation between interleukin-6 and septic shock in children

2012 ◽  
Vol 52 (6) ◽  
pp. 352
Author(s):  
Stephanie Yulianto ◽  
Ari Runtunuwu ◽  
Vivekenanda Pateda ◽  
Jose Mandei ◽  
Julius Lolombulan
Keyword(s):  
Septic Shock ◽  
Interleukin 6 ◽  
Clinical Signs ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Threatening Condition ◽  
Life Threatening ◽  
The Mean ◽  
Pediatric Sepsis

Background Sepsis is a life􀁆threatening condition and the mostcommon cause of death in intensive care units in developingcountries, such as Indonesia. The first clinical signs of sepsis areusually non􀁆spedfic. More specific signs and laboratory parametersoften occur late and are associated 'With organ dysfunction andhigh mortality rates. Interleukin􀁆6 (IL--6) is a biomarker reported tobe superior to clinical signs and conventional tests for sepsis. IL--6levels may indicate microorganism invasion, as well as progressionof infection into sepsis, severe sepsis, and septic shock.Objective To evaluate a correlation between interleukin (IL)􀁆6and septic shock in childrenMethods This cross􀁆sectional study was conducted in the pediatricintensive care unit of Prof. Dr. R.D. Kandou Hospital, Manado,between June to September 2011. Subjects were children withsepsis or septic shock aged 1 month to 13 years, v.ith diagnosesbased on the International Pediatric Sepsis Consensus ConferenceCriteria 2005. A one􀁆time measurement of IL--6 plasma levelswas done at the time of diagnosis. Data was analyzed by logisticregression test using SPSS version 17 software. A P value of <0.05indicated statistical significance.Results The mean IL--6 plasma level in the septic group was 1.68(95%CI 1.45 to 1.91) pg/mL and that of the septic shock groupwas 2.33 (95%CI 1.79 to 2.86) pg/mL. Our results showed astrong positive correlation between IL􀁆6 plasma levels v.ith theprobability of septic shock in children v.ith sepsis (regressioncoefficient􀁇1.3lO, P􀁇O.024).Conclusion Higher plasma IL--6 levels were associated v.ith ahigher risk of septic shock in children with sepsis. [Paediatrrndones.2012;52:352-5].

scholarly journals Influence of juvenile idiopathic arthritis on the quality of life of young adults in the transition period to adult rheumatologic care

2017 ◽  
Vol 2 (4) ◽  
pp. e020478
Author(s):  
Marta Dzhus
Keyword(s):  
Quality Of Life ◽  
Young Adults ◽  
Juvenile Idiopathic Arthritis ◽  
Transition Period ◽  
Disease Onset ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
The Impact

Background Young adults with juvenile idiopathic arthritis (JIA) often have an active disease with significant functional impairment in adulthood that can affect their physical and mental functions Aim To determine the impact of JIA on quality of life (QoL) in young adults with JIA during the transition healthcare Materials and methods The cross-sectional study of 89 young adults aged 16 to 22 years with a history of JIA regardless of the presence or absence of active inflammation at the time of the survey was performed in the Oleksandrivsky Central Clinical Hospital in Kyiv, Ukraine in the period between April 2015 and February 2017. 25 age- and sex-matched controls (without rheumatic disease) were included. There was performed an evaluation of the age at disease onset, duration, JIA activity, received therapy and quality of life Results Out of 89, 37 (41,6%) patients were considered to be in remission. Juvenile idiopathic arthritis had a large impact on the physical scales of quality of life. Patients with JIA had worse (p <0.001) physical health in comparison with the control group. The pain was the most important factor affecting the quality of life in cases of juvenile idiopathic arthritis. The indices responsible for the physical (p<0.001), role (borderline significance, p=0.04) functioning, and intensity of pain (p<0.001) were decreased, compared with the control group. However, the indicators responsible for psychological function in patients with JIA did not differ from the control group. The correlation analysis revealed significant negative association between disability severity (HAQ) and physical function (r=-0,56, p<0.001), role function (r=-0,33, p<0.001), pain intensity (r=-0,60, p<0.001), general health (r=-0,40, p=0.01), vital activity (r=-0,46, p<0.001), social function (r=-0,48, p<0.001), mental health (r=-0,42, p<0.001) Conclusion In our transitional cohort of patients at the era of biological therapies, juvenile idiopathic arthritis had a larger effect on the physical than mental SF-36 subscale. The pain was the main factor influencing the quality of life

scholarly journals Is There an Association Between Multiple Sclerosis Epidemic and Socioeconomic Status in Iran? - A Descriptive-analytical Cross-sectional Study

2022 ◽  
Author(s):  
Hossein Mozhdehipanah ◽  
Ali Emami ◽  
Shima Mohammadhoseini Targhi ◽  
Fatemeh Kazemi ◽  
Ali Sarbazi-Golezari ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Socioeconomic Status ◽  
Disease Onset ◽  
Cross Sectional Study ◽  
Special Treatment ◽  
Sectional Study ◽  
Monthly Income ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Mean

Abstract Background: Multiple sclerosis (MS) is a key neurogenic cause of disability among young populations. Assessing the parameters affecting MS severity is vital to reduce the disease burden. the objective of this study is to determine the relationship between socioeconomic status (SES) and MS severity among Iranian young adults.Methods: A descriptive-analytical cross-sectional study was conducted by 180 patients (142 females and 38 males) with MS selected by a non-probability and consecutive sampling was conducted during September 2018-2019. The socio-demographic and primary clinical data were collected by a self-developed questionnaire and face-to-face interviews, respectively. The expanded disability status scale (EDSS) was used to assess the physical disability degree and the overall neurological function of patients.Results: The mean age of patients and MS onset was 27.54 and 35.58 years, respectively. The majority of patients were married (68.3%) while were living in cities (74.4%). The mean values of unemployment, homeownership, and monthly income were determined to be 54.4%, 71.7%, and 11,078,330 IRR, respectively. The mean EDSS was 2.80±1.79 points. A weak positive correlation between EDSS and patients' age (P = 0.001, r = 0.246) and number of children (P = 0.001, r = 0.250) was found. There was no significant difference between EDSS and SES factors (i.e., disease onset age, treatment cost, and monthly income).Conclusions: As SES was not related to the MS severity, there is no need to take special treatment measures in patients with poor SES.

The prevalence of keratoconus in children with allergic eye disease in an Egyptian population

2020 ◽  
pp. 112067212094269
Author(s):  
Alyaa Saeed Ahmed ◽  
Mohamed-Sameh H El-Agha ◽  
Mahmoud Osama Khaled ◽  
Shireen Mostafa Shousha
Keyword(s):  
Allergic Conjunctivitis ◽  
Clinical Signs ◽  
Cross Sectional Study ◽  
Vernal Keratoconjunctivitis ◽  
Ophthalmological Examination ◽  
Ocular Allergy ◽  
Cross Sectional ◽  
Duration Of Symptoms ◽  
The Mean ◽  
Study Participants

Purpose: To determine the prevalence of keratoconus (KC) among children with ocular allergy. Methods: A cross-sectional study was conducted on all children presenting with ocular allergic disease from September 2017 to September 2018. All study participants were subjected to history taking (a specially designed questionnaire), routine ophthalmological examination, and corneal tomography. Results: A total of 79% of the study patients had vernal keratoconjunctivitis (VKC) while the remaining had perennial allergic conjunctivitis (10%), seasonal allergic conjunctivitis (9%) and atopic keratoconjunctivitis (2%). Manifest KC was seen in 7% of cases, suspect KC was found in 27% of cases, and 66% had no evidence of KC. For the manifest KC, 56% had clinical signs, while 44% were diagnosed by tomography. For the purpose of statistical analysis, the cohort was divided into group KC (manifest or suspicious KC) and group non-KC (no KC). The mean age was 11.2 years in group KC, and 9 years in group non-KC ( p < 0.001). The mean duration of allergic symptoms was 3.75 years in group KC, and 2.5 years in group non-KC ( p = 0.001). The mean duration of eye rubbing was 2.5 years in group KC, and 0.83 years in group non-KC ( p = 0.02). Systemic atopy was present in 35.3% of group KC, and in 12.5% in group non-KC ( p = 0.005). Conclusion: The overall prevalence of KC was 34%. Risk factors for the development of KC in patients with ocular allergy were age, duration of symptoms specially eye rubbing, systemic atopy and VKC. Tomographic diagnosis of KC can be present in absence of clinical signs.

scholarly journals AB0738 JUVENILE IDIOPATHIC ARTHRITIS AND SCHOOLING

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1398.2-1398
Author(s):  
H. Tantaoui ◽  
K. Nassar ◽  
S. Janani
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Age Of Onset ◽  
Secondary Level ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Professional Integration ◽  
Short And Long Term ◽  
The Mean ◽  
Attending Physicians ◽  
The Impact

Background:Juvenile idiopathic arthritis (JIA) refers to all chronic inflammatory rheumatism in children without a recognized cause, onset before the age of 16. JIA is associated with significant short- and long-term disability, which influences the education and socio-professional integration of patients who suffers from it.Objectives:Evaluate the impact of JIA on the education and professional integration of affected patients.Methods:This is a retrospective, descriptive and cross-sectional study carried out in the rheumatology department.We included all patient followed in our JIA training.The following information was collected from a questionnaire survey: Educational attainment, main problems experienced during studies, cause of dropping school, and professional data.Results:Forty-two patients were included. The average age was 27.15 years old [18 - 61 years old]. Sex-Ratio (M / F) was 0.9. The forms of JIA were dominated by spondyloarthropathy (48.64%) and the seropositive polyarticular form (18.91%). The mean age of onset of JIA was 10.8 years [6 months - 16 years]. The mean duration of JIA progression was 14.4 years [4 - 27 years].Regarding education, 2.94% were illiterate, 23.52% had a primary level, 55.87% a secondary level and 17.64% a higher level. The majority of patients (85%) experienced several problems during their studies: joint pain and stiffness (73.52%), absenteeism (50%), limitation in activities (26.47%), problem with adaptation and social integration (11.76%) and fatigue (5.88%). Only 2.94% of patients benefited from an individualized reception protocol apart from a sports exemption which represents 38.23%. 73.52% of patients received encouragement to continue their studies by those around them (parents, teachers and attending physicians).Discontinuation of schooling was observed in 70.58% of patients with 8.82% of patients dropping school before the onset of JIA and 61.76% of patients related to JIA. School studies were still ongoing in 23.52% of patients.Regarding the professional side, unemployment affects 52.94% of these patients and workers represent 23.52%.Conclusion:In our series, the level of education of JIA patients does not exceed secondary level in 80% of cases. The implementation of an individualized reception protocol is strongly recommended to facilitate the education of these patients and to fight against the main problems experienced. The professional integration of patients with JIA should also be adopted.Disclosure of Interests:None declared

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