Computationally replicating the Smith et al. (2015) positive-negative mode linking functional connectivity and subject measures

AbstractUnderstanding brain functionality and predicting human behavior based on functional brain activity is a major goal of neuroscience. Numerous studies have been conducted to investigate the relationship between functional brain activity and attention, subject characteristics, autism, psychiatric disorders, and more. By modeling brain activity data as networks, researchers can leverage the mathematical tools of graph and network theory to probe these relationships. In their landmark study, Smith et al. (2015) analyzed the relationship of young adult connectomes and subject measures, using data from the Human Connectome Project (HCP). Using canonical correlation analysis (CCA), Smith et al. found that there was a single prominent CCA mode which explained a statistically significant percentage of the observed variance in connectomes and subject measures. They also found a strong positive correlation of 0.87 between the primary CCA mode connectome and subject measure weights. In this study, we computationally replicate the findings of the original study in both the HCP 500 and HCP 1200 subject releases. The exact computational replication in the HCP 500 dataset was a success, validating our analysis pipeline for extension studies. The extended replication in the larger HCP 1200 dataset was partially successful and demonstrated a dominant primary mode.

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Mortal Body, Immortal Mind

Forum Philosophicum ◽

10.35765/forphil.2012.1701.01 ◽

2012 ◽

Vol 17 (1) ◽

pp. 5-26

Author(s):

Hans Goller

Keyword(s):

Brain Activity ◽

The Body ◽

Activity Data ◽

Brain Functions ◽

Body Experiences ◽

Research Findings ◽

The Relationship ◽

Near Death Experiences ◽

The Brain ◽

Alternative Theories

Neuroscientists keep telling us that the brain produces consciousness and consciousness does not survive brain death because it ceases when brain activity ceases. Research findings on near-death-experiences during cardiac arrest contradict this widely held conviction. They raise perplexing questions with regard to our current understanding of the relationship between consciousness and brain functions. Reports on veridical perceptions during out-of-body experiences suggest that consciousness may be experienced independently of a functioning brain and that self-consciousness may continue even after the termination of brain activity. Data on studies of near-death-experiences could be an incentive to develop alternative theories of the body-mind relation as seen in contemporary neuroscience.

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Derivation and Performance of Standardized Enhanced Liver Fibrosis (ELF) Test Thresholds for the Detection and Prognosis of Liver Fibrosis

The Journal of Applied Laboratory Medicine ◽

10.1373/jalm.2018.027359 ◽

2019 ◽

Vol 3 (5) ◽

pp. 815-826 ◽

Cited By ~ 9

Author(s):

James Day ◽

Preya Patel ◽

Julie Parkes ◽

William Rosenberg

Keyword(s):

Liver Fibrosis ◽

Delphi Panel ◽

Test Results ◽

Hazard Ratios ◽

Test Thresholds ◽

And Performance ◽

Using Data ◽

Relationship Of ◽

The Relationship ◽

Selection Of

Abstract Introduction Noninvasive tests are increasingly used to assess liver fibrosis and determine prognosis but suggested test thresholds vary. We describe the selection of standardized thresholds for the Enhanced Liver Fibrosis (ELF) test for the detection of liver fibrosis and for prognostication in chronic liver disease. Methods A Delphi method was used to identify thresholds for the ELF test to predict histological liver fibrosis stages, including cirrhosis, using data derived from 921 patients in the EUROGOLF cohort. These thresholds were then used to determine the prognostic performance of ELF in a subset of 457 patients followed for a mean of 5 years. Results The Delphi panel selected sensitivity of 85% for the detection of fibrosis and >95% specificity for cirrhosis. The corresponding thresholds were 7.7, 9.8, and 11.3. Eighty-five percent of patients with mild or worse fibrosis had an ELF score ≥7.7. The sensitivity for cirrhosis of ELF ≥9.8 was 76%. ELF ≥11.3 was 97% specific for cirrhosis. ELF scores show a near-linear relationship with Ishak fibrosis stages. Relative to the <7.7 group, the hazard ratios for a liver-related outcome at 5 years were 21.00 (95% CI, 2.68–164.65) and 71.04 (95% CI, 9.4–536.7) in the 9.8 to <11.3 and ≥11.3 subgroups, respectively. Conclusion The selection of standard thresholds for detection and prognosis of liver fibrosis is described and their performance reported. These thresholds should prove useful in both interpreting and explaining test results and when considering the relationship of ELF score to Ishak stage in the context of monitoring.

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The Decay of Disease Association with Declining Linkage Disequilibrium: A Fine Mapping Theorem

10.1101/052381 ◽

2016 ◽

Cited By ~ 1

Author(s):

Mehdi Maadooliat ◽

Naveen K. Bansal ◽

Jiblal Upadhya ◽

Manzur R. Farazi ◽

Zhan Ye ◽

...

Keyword(s):

Monte Carlo ◽

Linkage Disequilibrium ◽

Fine Mapping ◽

Disease Model ◽

Disease Association ◽

Simple Relationship ◽

Locus System ◽

Using Data ◽

Relationship Of ◽

The Relationship

AbstractSeveral important and fundamental aspects of disease genetics models have yet to be described. One such property is the relationship of disease association statistics at a marker site closely linked to a disease causing site. A complete description of this two-locus system is of particular importance to experimental efforts to fine map association signals for complex diseases. Here, we present a simple relationship between disease association statistics and the decline of linkage disequilibrium from a causal site. A complete derivation of this relationship from a general disease model is shown for very large sample sizes. Quite interestingly, this relationship holds across all modes of inheritance. Extensive Monte Carlo simulations using a disease genetics model applied to chromosomes subjected to a standard model of recombination are employed to better understand the variation around this fine mapping theorem due to sampling effects. We also use this relationship to provide a framework for estimating properties of a non-interrogated causal site using data at closely linked markers. We anticipate that understanding the patterns of disease association decay with declining linkage disequilibrium from a causal site will enable more powerful fine mapping methods.

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Airline Financial Distress and Customer Satisfaction

Journal of the Transportation Research Forum ◽

10.5399/osu/jtrf.48.1.1771 ◽

2011 ◽

Vol 48 (1) ◽

Author(s):

Dina Ribbink ◽

Christian Hofer ◽

Martin Dresner

Keyword(s):

Customer Service ◽

Airline Industry ◽

Financial Distress ◽

Service Levels ◽

The Third ◽

Time Performance ◽

Using Data ◽

Relationship Of ◽

The Impact ◽

The Relationship

An investigation is conducted on the effect of financial distress on customer service levels in the U.S. airline industry. Using data from the first quarter of 1998 to the third quarter of 2006, we employ a seemingly unrelated regressions (SUR) model to analyze the impact of financial distress on three measures of customer service. We find that higher financial distress is associated with better on-time performance of airlines and fewer lost bags. The relationship of airline financial distress to the number of bumped customers, however, is insignificant.

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Hubungan Perilaku Perdagangan Investor Dengan Volume Perdagangan Di Bursa Efek Indonesia

Jurnal Manajemen Teori dan Terapan | Journal of Theory and Applied Management ◽

10.20473/jmtt.v2i1.2377 ◽

2009 ◽

Vol 2 (1) ◽

Author(s):

Ghazali Syamni

Keyword(s):

Trading Volume ◽

Stock Exchange ◽

Time Interval ◽

Time Intervals ◽

Using Data ◽

Changes Over Time ◽

Relationship Of ◽

The Relationship ◽

Order Pattern ◽

Over Time

This paper examines the relationship of behavior trading investor using data detailed transaction history-corporate edition demand and order history in Indonesia Stock Exchange during period of March, April and May 2005. Peculiarly, behavior placing of investor order at trading volume. The result of this paper indicates that trading volume order pattern to have pattern U shape. The pattern happened that investors have strong desires to places order at the opening and close of compared to in trading periods. While the largest orders are of market at the opening indicates that investor is more conservatively when opening, where many orders when opening has not happened transaction to match. In placing order both of investor does similar strategy. By definition, informed investors’ orders more large than uninformed investors. If comparison of order examined hence both investors behavior relatively changes over time. But, statistically shows there is not ratio significant. This implies behavior trading of informed investors and uninformed investors stable relative over time. The result from regression analysis indicates that informed investors to correlate at trading volume in all time intervals, but not all uninformed investors correlates in every time interval. This imply investor order inform is more can explain trading volume pattern compared to uninformed investor order in Indonesia Stock Exchange. Finally, result of regression also finds that order status match has greater role determines trading volume pattern intraday especially informed buy match and informed sale match. While amend, open and withdraw unable to have role to determine intraday trading volume pattern.

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THE RELATIONSHIP BETWEEN DEVOTIONAL SANGEETHAM OF SWAMI TYAGAYA, BRAIN-MIND DYNAMICS AND GOD SPOT

Muallim Journal of Social Science and Humanities ◽

10.33306/mjssh/33 ◽

2019 ◽

pp. 431-440

Author(s):

Purushothaman Anantham

Keyword(s):

Spiritual Development ◽

Brain Activity ◽

Spiritual Experience ◽

Strong Positive Correlation ◽

Psychometric Assessment ◽

Questionnaire Data ◽

Pearson Product Moment Correlation ◽

Grand Total ◽

Different Types ◽

The Relationship

The rationale is that Saint Tyagaya’s devotional Sangeetham creates brain activity to contemplate on God and therefore God becomes neurologically real. This form of spiritual development and contemplative singing exercise could strengthen neurological circuits and manipulate a devotee’s emotion to produce love, empathy, compassion, benevolence and tolerance. The research is a validation of the psychometric assessment extending from Swami Tyagaya, devotional Sangeetham, God, neuro-psychology and spirituality. The methodology shows the development of a questionnaire survey with a grand total of Eighty two questions to measure five different types of subjects. The Questionnaire addresses the society’s knowledge, belief, devotion, attitudes and educational progress over the five subjects. The compilation of questionnaire was distributed to the Indian community in Malaysia. Four hundred and ten volunteers responded to tell their experiential views of Sangeetham, Swami Tyagaya, brain, devotion, God and spirituality. The Questionnaire data were analyzed using Pearson product-moment correlation coefficient. The result showed that there are strong positive correlation between Sangeetham, devotional reliance, God, brain Swami Tyagaya and spiritualism. These results conclusively indicate that Swami Tyagaya’s devotional Sangeetham strongly influences the spiritual experience of the Indian devotees in Malaysia.

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Servant Leadership from Multiple Domains and Follower Work Behavior

Journal of Management Spirituality & Religion ◽

10.51327/clqm9400 ◽

2021 ◽

Vol 18 (4) ◽

pp. 272-292

Author(s):

Mitchell Neubert ◽

Cindy Wu ◽

Kevin Dougherty

Keyword(s):

Servant Leadership ◽

Regulatory Focus ◽

Structural Equation ◽

Work Behavior ◽

Equation Modeling ◽

Working Adults ◽

Using Data ◽

Multiple Domains ◽

Relationship Of ◽

The Relationship

Managers and ministers exercise influence over their members inside and outside of their organizations. We examine the relationship of servant leadership from two contexts, an individual’s workplace and place of worship, with regulatory foci, and, in turn, entrepreneurial behavior and counterproductive work behavior (CWB) at work. Moreover, we contend that spiritual discipline (i.e., prayer and reading sacred texts) moderates the relationship of servant leadership to regulatory focus by altering the salience of each leader’s behavior. Using data collected in two waves from 912 working adults, we test the proposed relationships with multi-group structural equation modeling. Findings largely support the hypotheses and point toward important implications for servant leadership in both workplace and place of worship settings.

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The effects of chronic tDCS on functional brain activity and sustained attention performance

Brain Stimulation ◽

10.1016/j.brs.2018.12.766 ◽

2019 ◽

Vol 12 (2) ◽

pp. 536

Author(s):

R. Mc Kinley ◽

M. Sherwood ◽

C. Mullenger ◽

L. McIntire

Keyword(s):

Sustained Attention ◽

Brain Activity ◽

Functional Brain ◽

Attention Performance ◽

Functional Brain Activity

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Students’ Perception and Readiness towards Inter-Professional Learning

International Journal of Social Sciences and Management ◽

10.3126/ijssm.v5i3.20610 ◽

2018 ◽

Vol 5 (3) ◽

pp. 192-200

Author(s):

Javaria Mukhtar ◽

Muhammad Hussain ◽

Kousar Perveen ◽

Muhammad Afzal ◽

Syed Amir Gilani

Keyword(s):

Professional Learning ◽

Professional Education ◽

Cross Sectional Study ◽

Team Work ◽

Strong Positive Correlation ◽

Cross Sectional ◽

Positive Correlation ◽

Undergraduate Nursing ◽

Relationship Of ◽

The Relationship

Inter-professional learning is helpful for students to identify other professionals for team work and collaboration which results in improved patient care out come and also improve Communication among health professionals and patients. The purpose of this study was to explore the relationship between readiness and perception of students towards inter-professional learning. A correlation, cross-sectional study was done with Two hundred and eighty five undergraduate Nursing and Paramedical students from Jan, 2018 to May, 2018. Convenient sampling was used to collect data. The Readiness for Inter-Professional Learning Scale (RIPLS) and Interdisciplinary Education Perception Scale (IEPS) were used to measure the readiness and perception of students regarding inter-professional leaning. The data were analyzed using software Statistical Package for Social Science (SPSS) (Version 21). Spearman rho correlation test was used to explore the relationship of variables. The results showed statically significant positive correlation between the readiness and Perception of students regarding inter-professional learning (p=.000). This study indicated that there is strong positive correlation between readiness and perception of students towards inter-professional learning but students have least response towards team work and collaboration. Study suggests that inter-professional education should introduce in the curriculum of nursing and paramedical students to promote team work and share learning.Int. J. Soc. Sc. Manage. Vol. 5, Issue-3: 192-200

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