scholarly journals Post-acute COVID-19 syndrome negatively impacts health and wellbeing despite less severe acute infection

Author(s):  
Laura Tabacof ◽  
Jenna Tosto-Mancuso ◽  
Jamie Wood ◽  
Mar Cortes ◽  
Amy Kontorovich ◽  
...  

AbstractIntroductionOne of the noted features of COVID-19 is the spectrum of expressivity in symptoms among those with the disease, ranging from no or mild symptoms that may last a small number of days, to severe and/or longer lasting symptoms. It is emerging that many patients have long lasting symptoms, several months after initial infection with COVID-19. The aim of this research was to characterize post-acute COVID-19 syndrome (PACS).MethodsThis was a retrospective cross-sectional observational study. Participants were patients recovering from COVID-19 infection, enrolled in Mount Sinai Hospital’s COVID-19 Precision Recovery Program (PRP). Inclusion criteria were confirmed or probable (based on World Health Organization criteria) initial diagnosis of COVID-19; post-acute COVID-19 syndrome (defined as experiencing symptoms > 6 weeks since acute symptom onset) and being currently enrolled in the PRP during the months of July and August 2020. Study survey data were collected using REDCap. Demographic data, COVID-19 clinical data and patient-reported outcomes for breathlessness (Medical Research Council Breathlessness Scale), fatigue and quality of life (EuroQoL 5D-5L) were collected.Results84 individuals with PACS were included. Symptoms persisted at mean (range) 151 (54 to 255) days. The most prevalent persistent symptoms were fatigue (92%), loss of concentration/memory (74%), weakness (68%), headache (65%) and dizziness (64%). Most participants reported increased levels of disability associated with breathlessness, increased fatigue and reduced quality of life.ConclusionsPersistent symptoms following COVID-19 infection are prevalent, debilitating and appear to affect individuals regardless of acute infection severity or prior health status. More detailed research is required in order to identify specific symptom clusters associated with PACS, and to devise effective interventional strategies.

2017 ◽  
Vol 46 (5) ◽  
pp. 278-283
Author(s):  
Cinthia Nara Gadelha TEIXEIRA ◽  
Maria Imaculada de Queiroz RODRIGUES ◽  
Paulo Goberlanio de Barros SILVA ◽  
Myrna Maria Arcanjo FROTA ◽  
Maria Eneide Leitão de ALMEIDA

Abstract Introduction Quality of life (QL) is subjective and must be based on a multidimensional construct and on positive and negative factors in the individual’s life. Objective The objective of this study was to evaluate the QL of the students of the Postgraduate Program in Dentistry (PPGO) of the Federal University of Ceará. Material and method Cross-sectional study with a quantitative approach, conducted with 88 students regularly enrolled in PPGO. The QL was measured by the World Health Organization Questionnaire for Quality of Life-bref (WHOQOL-bref). For a better analysis of the QL scores, they were categorized into three levels: dissatisfaction, uncertainty and satisfaction. A multinomial logistic regression model was used. Result The majority of the respondents (55.7%) was classified in the area of satisfaction with QL, with 14,05 total average scores, corresponding to 62.8% of the total. By associating the socio-demographic data with the categories of analysis of QL, it was observed relevant in single students (p=0.005), those who considered themselves religious (p=0.041) and those who did not have a postgraduate scholarship (p=0.025), being evaluated in the area of dissatisfaction/uncertainty about the QL. Conclusion It was concluded that marital status, religion and scholarship in postgraduate school were relevant in the QL of stricto sensu postgraduate students in Dentistry.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Svetlana Orlova ◽  
Galina Dikke ◽  
Gisele Pickering ◽  
Eliso Djobava ◽  
Sofya Konchits ◽  
...  

AbstractThis study was aimed to assess the effectiveness of magnesium (Mg)-vitamin B 6 replenishment and its correlation with clinical status in pregnant women (PW), and quality of life in women with hormone-related conditions (HRCW) and hypomagnesemia (HME). Data collected in four observational studies were pooled and analysed. All women received Mg supplementation for 4 weeks. The proportion of women with normalized Mg level, and the correlation between serum Mg dynamics and number of symptoms/complaints (PW) or changes in World Health Organization quality of life questionnaire scores (WHOQOL; HRCW) were evaluated. 869 PW and 957 HRCW were included in the study. Normalization of serum Mg level to ≥ 0.66 mmol/L occurred in 92.1% of PW and 78.4% of HRCW, and to ≥ 0.8 mmol/L in 73.8% and 58.9%, respectively. Mg normalization was accompanied by a median decrease of 1 symptom and 1 complaint in PW. Serum Mg level increase by 0.1 mmol/L was associated to significant changes in the WHOQOL scores in HRCW. Treatment of HME with the Mg for approximately 4 weeks provided a high response rate of Mg serum level, was associated with an improvement in symptom severity and complaints in PW, and WHOQOL score in HRCW. A 0.8 mmol/L cut-off appeared to be more relevant in terms of patient-reported outcomes.


2021 ◽  
Vol 15 (3) ◽  
Author(s):  
Supriya Patil ◽  
Yamini Patil ◽  
Sanjay Kumar Patil

Diabetes is a chronic metabolic disorder that disturbs the quality of life (QOL) of patients. Therefore, evaluation of diabetes- related QOL could be a key outcome measure for its management. This study assessed the QOL in type 2 diabetes mellitus (T2DM) patients using the World Health Organization (WHO) quality of life (QOL)˗BREF questionnaire and disease-specific appraisal of diabetes scale (ADS). In this cross-sectional study, 520 T2DM patients were included. Patients’ demographic data, clinical information was collected through interviews, and the WHOQOL-BREF instrument and ADS were used for the QOL of patients. Statistical analysis was performed by using R software (Version 3.6.0). The mean ADS scores were lower in controlled diabetic subjects (18.50±3.08) and higher in uncontrolled diabetic subjects (19.29±2.73) (P<0.05). For WHOQOL-BREF, the mean scores for all the domains (overall general health, physical, psychological, social, and environmental) were significantly higher in controlled diabetic subjects (P<0.001). In addition, the age, duration of diabetes, associated comorbidities, treatment, and HbA1c level of patients showed a highly significant correlation with WHOQOL-BREF (P<0.001). Diabetic patients had poor-to-average QOL. Therefore, public health measures and education of diabetic patients are essential to create more awareness for improving the QOL of T2DM.


2017 ◽  
Vol 15 (2) ◽  
pp. 130-135 ◽  
Author(s):  
Walter Fernandes de Azevedo ◽  
Lígia Andrade da Silva Telles Mathias

ABSTRACT Objective To evaluate the quality of life of physicians and investigate to what extent it is affected by work addiction. Methods This is an exploratory, descriptive and cross-sectional study, conducted with 1,110 physicians. For data collection, we used a questionnaire with sociodemographic information, the World Health Organization Quality of Life BREF, and the Work Addiction Scale. Results Most physicians presented high quality of life. Female participants presented lower quality of life in the domains psychologic, environment and general (p<0.05). Quality of life was negatively correlated with the number of shifts (p<0.005). The higher the addiction to work, the lower the quality of life. Conclusion The research allowed understanding the implications of work addiction in the quality of life. Further studies are required to support the development of strategies that improve health conditions and quality of life of medical professionals.


2020 ◽  
Author(s):  
Mohammad Farris Iman Leong Bin Abdullah ◽  
Nor Shuhada Murad ◽  
Soo Huat Teoh ◽  
Mohd Afifuddin Mohamad

Abstract Purpose: Despite the significant impact of COVID-19 on mental health among university students, data on the related quality of life (QoL) are lacking in this group of the population. This study aimed to evaluate quality of life (QoL) and determine its association with various factors and social support among university students during the COVID-19 pandemic after the end of movement lockdown. Methods: This was an online, cross-sectional study recruited a total of 316 participants. Participants were administered a self-reported questionnaire to gather data on demographic, personal, clinical and psychological characteristics; the 21-item depression, anxiety and stress scale (DASS-21) to assess the severity of their depressive, anxiety and stress symptoms; the multidimensional scale of perceived social support (MSPSS) to assess the degree of social support; and the World Health Organization quality of life-BREF (WHOQoL-BREF) to assess QoL. Results: The psychological and social QoL scores were lower than the non-pandemic norms of the general population, while the physical health and environmental QoL scores were comparable. After adjusting for relevant demographic, personal, and clinical variables, religious coping; greater number of hours of online classes attended; and greater social support from family, friends and significant others were found to be significantly associated with higher QoL among the participants. Frustration because of study disruption, living in areas with a high prevalence of COVID-19 cases, and a higher severity of depressive and stress symptoms were significantly associated with lower QoL. Conclusion: COVID-19 impaired the QoL of university students even after the movement lockdown was lifted.


2021 ◽  
Vol 12 ◽  
Author(s):  
Rejane Coan Ferretti Mayer ◽  
Maíra Ramos Alves ◽  
Sueli Miyuki Yamauti ◽  
Marcus Tolentino Silva ◽  
Luciane Cruz Lopes

ContextPeople with mental disorders can acquire long-term disabilities, which could impair their functioning and quality of life (QoL), requiring permanent care and social support. Systematic data on QoL and functioning, which could support a better management of these people, were not available.ObjectiveTo analyze the QoL, level of functioning and their association with sociodemographic and clinical factors of people with mental disorders who underwent deinstitutionalization using assisted living facilities.MethodsA Cross-sectional study was conducted between July 2018 and July 2019, through interviews using the World Health Organization Quality of Life (WHOQOL-BREF) to determine the QoL scores, and the World Health Organization Disability Assessment Schedule (WHODAS 2.0) to determine the level of functioning. All adults (≥18 years old) with mental disorders, who underwent deinstitutionalization, users of assisted living facilities and assisted by the Psychosocial Assistance Centers III, in a city in the state of São Paulo, Brazil, were selected. For statistical analysis of the associated factors, Student’s t-test was used for dichotomous variables and ANOVA for polynomial variables. Pearson correlation coefficient was used to measure the association between QoL and functioning scores.ResultsOut of 359 people who underwent deinstitutionalization with mental disorders, 147 met the eligibility criteria. The mean total score for the WHOQOL-BREF was 66.5 ± 13.4 and the mean score for WHODAS 2.0 was 10.4 ± 7.6. An association was found between people who were studying (n = 65.8; 95%CI, 63.5–68.1 vs. n = 73.9; 95%CI, 67.5–80.3; p = 0.04) and better WHOQOL-BREF QoL scores or WHODAS 2.0 levels of functioning (n = 10.9; 95%CI, 9.6–12.2 vs. n = 5.1; 95%CI, 2.5–7.7; p = 0.01). A weak negative correlation (r = 0.41) emerged between higher QoL scores and functioning improvement.ConclusionThis study indicates that the QoL of the sample is associated by their functioning levels, which, in turn, may reflect on their social interactions. Public policies that favor interventions increasing socialization of this population can result in better health outcomes. The QoL and functioning scores provide valuable insights to develop public policies more suited to this population profile.


2018 ◽  
Vol 2 (2) ◽  
pp. 90-94
Author(s):  
Nanik Dwi Astutik

Abstrak Proses aging yang dialami oleh lanisa akan membawa beberapa perubahan di beberapa aspek seperti fisik, psikososial dan kapasitas intelektual lansia dimana hal ini sangat berhubungan erat dengan perubahan fungsi kognitif pada lansia. Fungsi kognitif yang baik diperlukan agar lansia dapat meningkatkan kualitas hidupnya terutama optimalisasi status fungsional, keadaan umum, pemulihan produktivitas, kreativitas, dan perasaan bahagianya. Tujuan penelitian ini adalah mengetahui pengaruh fungsi kognitif terhadap kualitas hidup lansia. Penelitian ini menggunakan cross sectional design dengan melibatkan 66 responden lansia. Alat ukur yang digunakan adalah menggunakan penilaian Mini Mental State Examination (MMSE) dan World Health Organization Quality Of Life (WHOQOL) – Bref. Analisis data menggunakan Regresi Linier Sederhana. Hasil analisis menunjukkan nilai p=0.000 <0.05 sehingga dapat disimpulkan bahwa ada pengaruh fungsi kognitif lansia terhadap kualitas hidup lansia. Adanya pengaruh ini disebabkan karena fungsi kognitif mempengaruhi kemampuan lansia dalam melakukan aktifitas normal sehari- hari baik aktivitas fisik maupun aktivitas secara sosial .   Kata Kunci: Fungsi Kognitif, Kualitas Hidup, Lansia


2020 ◽  
Vol 29 (21) ◽  
pp. 1260-1265
Author(s):  
Ali Alshraifeen ◽  
Sami Al-Rawashdeh ◽  
Kaye Herth ◽  
Karimeh Alnuaimi ◽  
Fatmeh Alzoubi ◽  
...  

Background: Hope is important for patients with end-stage renal disease receiving haemodialysis (HD) and hope is associated with quality of life (QoL). Studies examining hope among the HD population are limited and, as far as the authors know, have not been undertaken in Jordan. Aims: To examine levels of hope and QoL and to examine the association between hope and QoL in HD patients in Jordan. Methods: A cross-sectional design was used. A convenience sample of 202 patients from six different dialysis centres was recruited. The World Health Organization QOL-BREF and the Herth Hope Index were used. Findings: Moderate levels of hope (M=32.3±4.1) were reported. Respondents reported low mean scores for the physical domain of QoL (M=48.3±21.1) but not for the psychological and social relationship domains. Higher hope scores were associated with better QoL. Conclusion: The findings suggest a positive relationship between the level of hope and QoL in people receiving HD. Encouraging hope while caring for HD patients in clinical settings may improve their QoL. Understanding the relationship between hope and QoL may help healthcare providers to improve the quality of care for patients and their families.


Author(s):  
Anjan Sreeranga ◽  
P. Pavithra ◽  
Anand D. Meundi

Background: With the availability of highly effective antiretroviral treatment, HIV is transforming into a chronic condition, whose management is now experiencing problems of other chronic diseases, where quality of life (QOL) has become an important component of overall assessment of health care and management. This study was conducted with the objective of assessing the QOL and factors influencing it in HIV infected people on antiretroviral therapy (ART).Methods: A cross-sectional study was conducted at district ART center, Hassan. Purposive sampling was used to identify 148 HIV infected people on antiretroviral therapy, who were interviewed using a pretested questionnaire, assessing QOL with the World Health Organization (WHOQOL) HIV‑BREF.Results: The average age of the study population was 37.69 years. Majority of them were males 54.7% compared to 45.3% of females. Most of them resided in rural areas (87.8%). The educational status of the subjects was poor with 33.8% of them being illiterates. The mean score was highest for spirituality and social relationships domain and least for psychological domain. Age, education and socioeconomic status did not have any influence on the QOL. There was significant difference between QOL scores and clinical stages. Individuals in stage I and II had better scores compared to stage 3 and 4. QOL scores decreased with decreasing CD4 count.Conclusions: Our findings suggest that patient-reported measures of health status and related concepts may help provide a feasible, reliable and valid method to assess the impact of HIV/AIDS improve patient outcomes. 


2019 ◽  
Vol 36 (2) ◽  
Author(s):  
Yasir Aziz ◽  
Ahmad Yar Khan ◽  
Iqra Shahid ◽  
Muhammad Athar Majeed Khan ◽  
Aisha Aisha

Objective: To determine the quality of life of students of a private medical college in Karachi in Pakistan. Methods: This cross sectional study was conducted among 217 medical students of Liaquat College of Medicine and Dentistry, Karachi from June 2017 to March 2018. Students were selected by a stratified sampling method and the World Health Organization Quality of Life BREF Instruments (WHO QOL-BREF) was used for the above-mentioned study. Statistical analysis was performed using SPSS (Statistical Package for Social Sciences) version 21 and Analysis of variance (ANOVA). Independent t-test was used as p <0.05 significant. Results: A total of 250 questionnaires were distributed among 2nd year, 3rd year, 4th year and final year students and the response rate was 86.8%. Among them 48.5% (n=105) students were male and 51.5% (n=112) students were female, while 9.2% (n=20) students were currently ill and the other 90.8% (n=197) were healthy. Conclusion: Medical education influences the quality of life (QOL) of students adversely. Social relationships and environmental domain were satisfactory in private medical institutes whereas physical and psychological progress was low due to academic load which requires improvement either by physical activities such as fitness classes or other extra-curricular activities. doi: https://doi.org/10.12669/pjms.36.2.668 How to cite this:Aziz Y, Khan AY, Shahid I, Khan MA, Aisha. Quality of life of students of a private medical college. Pak J Med Sci. 2020;36(2):---------. doi: https://doi.org/10.12669/pjms.36.2.668 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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