scholarly journals The Relationship between Chronological Age, Dental Age, and Salivary Alkaline Phosphatase in Indonesian Children Aged 8-14 Years: A Cross-Sectional Study

Author(s):  
Sindy Cornelia Nelwan ◽  
Soegeng Wahluyo ◽  
Firli Cahaya Khairani ◽  
Ricardo Adrian Nugraha ◽  
Haryono Utomo ◽  
...  

BackgroundInability to predict dental age accurately has long been the Achilles heel of pediatric dentistry. Whilst dental age has an important aspect in clinical practice, saliva can be one of the most practically important diagnostic tools to estimate biological age.AimsThis study was aimed to analyze a correlation between chronological age, dental age, and salivary alkaline phosphatase in Indonesian children aged 8-14 years.MethodsThis study was an observational study with cross-sectional design. Twenty healthy children (10 boys; age 10.504 ± 1.895 years) were selected by a consecutive sampling. Chronological age was assessed by recording date of birth. Dental age was assessed by orthopantamogram following Demirjian’s method. Salivary samples were collected by passive drool method and estimation of alkaline phosphatase was done by autoanalyzer.ResultsNormality test was assessed using Kolmogorov-Smirnov and Shapiro-Wilk test. Statistical analyses were assessed using Spearman’s rank-order correlation coefficients. Results are presented as mean ± standard deviation (SD). Mean chronological age was10.504 ± 1.895 years, mean Demirjian’s score was 91.74 ± 5.972, and mean salivary alkaline phosphatase was 291.563 ± 115.135 pg/ml. There is a very strong positive correlation between chronological age and dental age (r=+0.804; p<0.001). On the contrary, levels of salivary alkaline phosphatase was negatively correlated to dental age (r=-0.780; p<0.001) and chronological age (r=-0.508; p=0.022).ConclusionsThis study showed a strong correlation between dental age, chronological age, and salivary alkaline phosphatase; hence, estimation of dental age and salivary alkaline phosphatase in Indonesian children during early and late childhood has significant meaning to chronological age.

2011 ◽  
Vol 52 (1) ◽  
pp. 32-35 ◽  
Author(s):  
Shekhar Grover ◽  
Charu Mohan Marya ◽  
J Avinash ◽  
Nidhi Pruthi

Introduction Accurate age data are always necessary in medicine and dentistry, and are also important to assess maturity and estimate age in a number of disciplines, such as forensic odontology, paediatric and preventive dentistry, orthodontics, etc. Aim This investigation determines the accuracy of dental age estimation and its comparison with chronological age by two methods: Demirjian's and Willems’. Materials and methods Tooth development was assessed in seven left mandibular teeth from 215 orthopantomograms (OPGs) belonging to healthy children aged 6–15 years selected by convenience sampling, from patients of the Sudha Rustagi College of Dental Sciences & Research, Faridabad, and were staged according to Demirjian's and Willems’ scales. The statistical analysis was performed using the unpaired ‘ t’-test and the correlation was analysed using Karl Pearson's correlation coefficients test. Results Overall, Willems’ method was found to be more accurate with a mean age overestimation of 0.36 years (SD = 0.38) in boys and 0.24 years (SD = 0.36) in girls, and Demirjian's method produced a mean overestimation of 0.66 years (SD = 0.41) in boys and 0.56 years (SD = 0.43) in girls, respectively. Also, correlation between the two methods revealed a high coefficient value, 0.9947 for boys and 0.9944 for girls ( P < 0.05). Conclusion Despite the favourable result of Willems’ method in comparison with Demirjian's method, this study demonstrated a high correlation coefficient between both chronological and obtained dental age, thus confirming their potential applicability in clinical practice and forensic dentistry.


2021 ◽  
Vol 11 (1) ◽  
pp. 40-45
Author(s):  
Sumita Upadhyay ◽  
Sijan Paudyal ◽  
Prashant Khatiwada ◽  
Bibardha Khanal ◽  
Rasna Shrestha

Introduction: Dental age estimation using orthopantomogram is very useful in pediatric dentistry, orthodontics in clinical diagnosis and treatment planning and also has forensic application. Demirjian method is widely used for age estimation and Willems method has been suggested to be accurate than Demirjian in various populations. To estimate the dental age of children in a specific population of Nepal by Demirjian and Willems method, compare them with the chronological age and assess their applicability. Materials and Method: Digital orthopantomograms of 5 to 14 years of children were used to estimate the dental age by Demirjian’s 7- teeth method and Willems method. Descriptive statistics was used and mean with standard deviation was calculated for gender and age of the samples. Paired t-test was used for comparison of chronological age with dental age. P < 0.05 was considered as statistically significant.Pearson correlation was used to assess the correlation between chronological and dental age in both the genders. Result: By Demirjian method, there was an underestimation of 0.276 years in males and 0.194 in females and by Willems method, 0.652 in males and 0.847 in females which were statistically significant. There was an underestimation of dental age in all the age groups except in the age group of 5,7 and 14 for Demirjian age which was statistically nonsignificant. Pearson correlation demonstrated strong positive correlation between chronological age and dental age. Conclusion: The underestimation of dental age was more by Willems method as compared to Demirjian method. There was a strong positive relationship between chronological age and dental age in both the genders. Demirjian’s 7- teeth method was more applicable as compared to Willems method when tested in selected Nepalese children population


JKCD ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 9-11
Author(s):  
Sadaf Ambreen

Objectives: To compare Demirjian Dental scoring method with Greulich-Pyle (GP) Skeletal method of age estimation in pubertal children. Materials and Methods: Sample of the study included 267 male healthy subjects of 11-16 years of age group.. Demirjian Scoring system was utilized to evaluate the orthopantomograms to assess their Dental age and the Hand-Wrist radiographs were analyzed to calculate the skeletal age by utilizing GP atlas. Chronological age was obtained from the date of birth of the subject .Both methods were compared with one another and with the chronological age. It was a cross-sectional study and only healthy male subjects without any clinical abnormalities were included in the study. Results: A total of 267 male subjects of 11-16 years of age group were assessed by Demirjian and Greulich Pyle Methods. Both were compared with Chronological Age. Data obtained was statistically analyzed and the Student “t” test was applied in the study population. The mean difference between Chronolgical age and dental age was 0.69years and that of chronological age and skeletal age was 0.87 years. It was observed from dental age assessment that it does not differ much from the skeletal age. Conclusion: It was concluded that Demirjian method of Age Estimation is more precise than Greulich Pyle method of Age Estimation. Furthermore both methods can be used selectively in Medicolegal cases to access bone age which can be easily correlated to chronological age.


2020 ◽  
Author(s):  
Marta Macarena Paz Cortés ◽  
Rosa Rojo ◽  
Esther Alia García ◽  
Maria Rosa Mourelle Martínez

Abstract Background: The objective of this study was to evaluate and compare the validity and accuracy of the Willems, Demirjian and Nolla methods in predicting chronological age in a Spanish ethnicity population. Methods: A sample of 604 orthopantomographs of Spanish children aged 4 to 14 years was evaluated by two independent evaluators. Descriptive statistics were applied to calculate the chronological age and dental age, presenting the mean and standard deviation. The difference between dental age and chronological age was calculated for each method. A positive result indicated an overestimation and a negative figure indicated an underestimation. The Wilcoxon test for paired data and Spearman's correlation coefficient were applied by age groups and gender to compare the chronological age and dental age of each method (that of Willems, Demirjian and Nolla). Statistical tests were performed at a 95% confidence level. Results: The interexaminer agreement was 0.98 (p = 0.00), and the intraexaminer agreement was 0.99 (p = 0.00). The Willems method significantly overestimated the age of boys (0.35 years (0.93)) and girls (0.17 years (0.88)). The Demirjian method significantly overestimated the age of boys (0.68 years (0.95)) and girls (0.73 years (0.94)). The Nolla method significantly underestimated age in boys (0.44 years (0.93)) and girls (0.82 years (0.98)). Conclusions: In the Spanish population, the use of the Demirjian method for legal and medical purposes is frequent. This study reveals that the Willems method is more appropriate due to its greater precision in estimating dental age.


2020 ◽  
Vol 11 (2) ◽  
pp. 2205-2209
Author(s):  
Trelia Boel ◽  
Dewi Kartika ◽  
Ervina Sofyanti ◽  
Dennis ◽  
Navanitha Naidu

Estimation of dental age in forensic odontology is crucial in biological dentistry Coronal Pulp Cavity Index (CPCI) as one method to check the correlation between the reduction of the coronal pulp cavity and chronological age. The present study aims to find out whether CPCI method can be used to estimate the dental age on lower second premolar and first molar with periapical radiographic analysis. The cross sectional study was conducted on 60 patients (30 males and 30 females) in the age range of 21 and 30 years. They were subjected to periapical radiographs on lower second premolar and first molar. The Coronal Pulp Cavity Height (CPCH) and Coronal Length (CL) was measured using vision measuring scope DC 3000 and electronic digital caliper. The values obtained were subjected into the formula of TCI = [CPCL × 100]/CL. The mean of TCI score and average chronological age were analyzed using paired T test to find out the correlation between the chronological age and the estimated dental age, P > 0.05 is considered as significant. There was no significant difference between the estimated dental age and chronological age in both lower second premolars (p=0.119) and first molars (p=0.224). CPCI method can be used to estimate the dental age on healthy lower second premolar and first molar.


2019 ◽  
Vol 24 (4) ◽  
pp. 389-396
Author(s):  
Alan M. Chen ◽  
Kunal B. Karani ◽  
J. Michael Taylor ◽  
Bin Zhang ◽  
Andrew Furthmiller ◽  
...  

OBJECTIVEAlthough intracranial arterial aneurysms (IAAs) of childhood are usually idiopathic, it is possible that underlying arteriopathy escapes detection when using conventional diagnostic tools. Quantitative arterial tortuosity (QAT) has been studied as a biomarker of arteriopathy. The authors analyzed cervicocerebral QAT in children with idiopathic IAAs to assess the possibility of arteriopathy.METHODSCases were identified by text-string searches of imaging reports spanning the period January 1993 through June 2017. QAT of cervicocerebral arterial segments was measured from cross-sectional studies using image-processing software. Other imaging and clinical data were confirmed by retrospective electronic record review. Children with idiopathic IAAs and positive case controls, with congenital arteriopathy differentiated according to aneurysm status (with and without an aneurysm), were compared to each other and to healthy controls without vascular risk factors.RESULTSCervicocerebral QAT was measured in 314 children: 24 with idiopathic IAAs, 163 with congenital arteriopathy (including 14 arteriopathic IAAs), and 127 healthy controls. QAT of all vertebrobasilar segments was larger in children with IAAs (idiopathic and arteriopathic forms) (p < 0.05). In children with congenital arteriopathy without an aneurysm, QAT was decreased for the distal cervical vertebral arteries and increased for the supraspinal vertebral artery relative to healthy children. QAT of specific cervicocerebral segments correlated with IAA size and rupture status.CONCLUSIONSCervicocerebral QAT is a biomarker of arteriopathy in children with IAA, even in the absence of other disease markers. Additional findings suggest a correlation of cervicocerebral QAT with IAA size and rupture status and with the presence of IAA in children with congenital arteriopathy.


2021 ◽  
Vol 5 (1) ◽  
pp. 106
Author(s):  
Jessica Ferdi ◽  
Saptawati Bardosono ◽  
Bernie Endyarni Medise

Introduction: Iron is essential for child’s development and growth. Children’s iron requirements are secured from daily food intake that might be affected by Covid-19 pandemic. This study aims to determine iron intake and its relationship with ferritin and hemoglobin levels as indicators of iron status among children in Jakarta.Method: This cross-sectional study was conducted in Kampung Melayu, Jakarta from September to October 2020. Seventy seven healthy children aged 24–36 months were taken using total population sampling method. Interviews were conducted to obtain characteristics data and iron intake using a semi-quantitative-food frequency questionnaire (SQ-FFQ). Blood tests are performed to check the levels of ferritin (controlled by hs-CRP value), and hemoglobin.Pearson’s/Spearman’s correlation test was performed using SPSS version 20.0. Result: Median of iron intake was 9.6 (1.5–40,7) mg/day, in which 33.8% of subjects was below the Indonesian Recommended Dietary Allowance (RDA) recommendation. The median ferritin value was 18.1 (1.4–91.1) 𝜇g/L and the hemoglobin was 11.8 (6.6–15.2) g/dL, in which 40.3% and 27.3% subjects with iron insufficient-deficient and anemia, respectively. There were  positive correlations between iron intake and ferritin (r = 0.328, p = 0.002) and iron intake and hemoglobin (r = 0.308, p = 0.003). A strong positive correlation was found between ferritin and hemoglobin (r = 0.769, p < 0.001).Conclusion: Iron intake of children aged 24–36 months had a weak positive correlation with ferritin and hemoglobin level. Keywords: children 24–36 months, ferritin, hemoglobin, iron intake, Jakarta


2021 ◽  
Vol 58 (5) ◽  
pp. 612-618
Author(s):  
Evgenija Markovic ◽  
Nemanja Marinkovic ◽  
Ksenija Zelic ◽  
Petar Milovanovic ◽  
Marija Djuric ◽  
...  

Objective: To assess dental age and deviations of dental from chronological age according to the Willems and Cameriere methods (European formula) in patients with cleft lip and/or cleft palate (CL/P) and compare it with control group. Design: Retrospective cross-sectional study. Setting: Clinic of Orthodontics. Participants: Sixty-nine patients with CL/P between 6 and 15 years of age (55 with unilateral and 14 with bilateral CL/P) with 148 panoramic radiographs. The same number of radiographs was examined in the age-matched control group. Main Outcome Measures: Estimation and comparison of dental age and differences of dental from chronological age in relation to the type of cleft, sex, and age in the group of patients with and without CL/P according to Willems and Cameriere method. Results: No significant intersex and intergroup differences were found in deviations of dental from chronological age according to Cameriere method ( P > .05). Significant difference in deviation of dental from chronological age was found between the patients with and without CL/P according to Willems method ( P < .001). Conclusion: Cameriere European formula for dental age estimation, which is not influenced by sex and tooth morphology, showed similar dental development of children with and without CL/P. However, Willems method detected that deviation of dental from chronological age significantly differed between children with and without clefts.


2020 ◽  
pp. 105566562094477
Author(s):  
Taner Ozturk ◽  
Husniye Gumus ◽  
Gulce Ozturk

Objective: The relationship between dental and skeletal development levels was determined in individuals with cleft lip and palate and a control group comprising individuals without cleft lip and palate. Design: Retrospective, cross-sectional study. Setting: A university clinic specializing in orthodontic and pedodontic care. Patients: A total of 198 patients with cleft lip and palate (99 females, 11.66 ± 2.36 years; 99 males, 12.44 ± 2.33 years) and 198 patients without cleft lip and palate (99 females, 11.88 ± 2.26 years; 99 males, 12.99 ± 2.25 years). Interventions: None. Main Outcome Measures: The Demirjian method and cervical vertebra maturation method were used to evaluate panoramic and lateral cephalometric radiographs, respectively. The Fishman maturation predictors were determined from hand-wrist radiographs. Results: Statistically significant correlations were found between the chronological age and the dental age in both the groups ( P < .05). Significant correlations between skeletal maturation indicators and dental maturation indicators were observed in both groups and sexes ( P < .05), with a stronger correlation among teeth with incomplete dental maturation. Dental age was found to be significantly lower (female, P = .001; male, P = .001) in individuals with cleft lip and palate (female, 11.71 ± 2.58 years; male, 12.51 ± 2.62 years) compared to those in the control group (female, 12.95 ± 2.47 years; male, 13.64 ± 2.37 years). Conclusions: A high correlation between the results of the evaluated radiographic methods and chronological age supports their use for accurate age estimation in the patients with cleft lip and palate.


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