scholarly journals Brain-behaviour modes of covariation in healthy and clinically depressed young people

2018 ◽  
Author(s):  
Agoston Mihalik ◽  
Fabio S. Ferreira ◽  
Maria J. Rosa ◽  
Michael Moutoussis ◽  
Gabriel Ziegler ◽  
...  

AbstractUnderstanding how variations in dimensions of psychometrics, IQ and demographics relate to changes in brain connectivity during the critical developmental period of adolescence and early adulthood is a major challenge. This has particular relevance for mental health disorders where a failure to understand these links might hinder the development of better diagnostic approaches and therapeutics. Here, we investigated this question in 306 adolescents and young adults (14-24y, 25 clinically depressed) using a multivariate statistical framework, based on canonical correlation analysis (CCA). By linking individual functional brain connectivity profiles to self-report questionnaires, IQ and demographic data we identified two distinct modes of covariation. The first mode mapped onto an externalization/internalization axis and showed a strong association with sex. The second mode mapped onto a well-being/distress axis independent of sex. Interestingly, both modes showed an association with age. Crucially, the changes in functional brain connectivity associated with changes in these phenotypes showed marked developmental effects. The findings point to a role for the default mode, frontoparietal and limbic networks in psychopathology and depression.

2020 ◽  
Vol 11 ◽  
Author(s):  
Astri J. Lundervold ◽  
Anne Halmøy ◽  
Emilie S. Nordby ◽  
Jan Haavik ◽  
Jocelyn I. Meza

Introduction: Emotional fluctuations and mood swings are common among adults with Attention Deficit/Hyperactivity Disorder (ADHD). Here we investigated if these problems could be retrospectively traced back to childhood behavior.Methods: Adults with an ADHD diagnosis (n = 502, 48% female) and a population-based control sample (n = 818, 59% female) completed the Adult ADHD Self-report Scale (ASRS), the Wender Utah Rating Scale (WURS) and the Mood Disorder Questionnaire (MDQ). All participants also provided self-reported information about co-existent psychiatric and somatic diseases, and demographic data. Reports on the MDQ were used to define subgroups with [MDQ(+)] and without [MDQ(–)] life-time periods of emotional fluctuations and the WURS scale was used to retrospectively assess childhood ADHD related behaviors and symptoms.Results: 50.2% of the ADHD group and 5% of the controls were defined with emotional fluctuations [MDQ(+)]. Childhood behavior ratings of “impulsivity,” “loosing of control,” and “trouble with authorities” independently predicted emotional fluctuations reported in adulthood via logistic regression analyses. Inclusion of these three items in a classification analysis gave an accuracy score around 70% in identifying each of the two MDQ categories in the ADHD group.Discussion: The strong association between self-reported features of emotional problems in childhood and in adulthood suggests a trajectory that should be detected and remediated at an early age. Future longitudinal studies should prioritize the examination of developmental mechanisms explaining the persistence of emotional problems from childhood into adulthood.


2012 ◽  
Vol 18 (9) ◽  
pp. 1326-1333 ◽  
Author(s):  
CA Young ◽  
RJ Mills ◽  
J Woolmore ◽  
CP Hawkins ◽  
A Tennant

Background: Self-efficacy concerns the individual’s belief that he or she is capable of performing a certain task and producing a desired effect, i.e. it reflects the person’s perceptions of their capability for specific tasks, as distinct from their actual ability. Self-efficacy has been shown to influence motivation, psychological well-being, adherence with treatment regimes and quality of life in multiple sclerosis and other conditions. Objective: To develop a unidimensional scale of MS self-efficacy with robust psychometric properties, suitable for patient self report. Methods: A questionnaire pack covering three MS self-efficacy scales, the Dispositional Resilience Scale and demographic data was posted to MS patients from two MS databases. Data underwent Rasch analysis. Results: Response rate was 309/600 (51.5%). None of the existing MS self-efficacy scales were unidimensional. A new 12-item scale, created by combining items from our two scales, was shown to fit the Rasch model, was unidimensional, and invariant for gender, education and disease duration. Conclusion: The Unidimensional Self-Efficacy scale for MS (USE-MS) provides a simple summated scale for an ordinal estimate of a persons’ self efficacy. A transformation to interval scaling is available for use in the calculation of change scores and effect sizes.


Author(s):  
Amy E Morrison ◽  
Francesco Zaccardi ◽  
Sudesna Chatterjee ◽  
Emer Brady ◽  
Yvonne Doherty ◽  
...  

Abstract Aims Self-compassion is a modifiable characteristic, linked with psychological well being and intrinsic motivation to engage in positive health behaviours. We aimed to explore levels of self-compassion in individuals with type 2 diabetes (T2DM) and their association with levels of depression, diabetes-related distress and glycaemic control. Methods A cross-sectional study in 176 patients with T2DM in Leicester, UK, using three self-report questionnaires: the Self Compassion Scale (SCS); Patient Health Questionnaire (PHQ-9), and Diabetes Distress Scale (DDS-17). Demographic data, medical history and blood samples were collected. Results Majority of participants were male (n=120, 68.2%), with median [IQR] age and HbA1c of 66 [60, 71] years and 7.3 [6.7, 8.0] %, respectively. Multivariable analysis adjusting for age, gender, ethnicity and diabetes duration revealed significant association of all three scores with HbA1c: per one standard deviation increase of each score, a -0.16% reduction in HbA1c for SCS (p=0.027), 0.21% increase for PHQ-9 (p=0.012) and 0.33% increase for DDS-17 (p<0.001). Conclusions Higher levels of self-compassion and lower levels of depressive symptoms were associated with significantly better long-term diabetes control. These results reinforce the importance of emphasis on psychological parameters, including self-compassion, in the multi-disciplinary management of T2DM. We identify this as a potential area for intervention in UK practice.


2018 ◽  
Vol 8 (12) ◽  
pp. 105 ◽  
Author(s):  
Rawan Saleem Alghamdi ◽  
Hoda Mohamed Nafee ◽  
Awatef El-Sayed ◽  
Saad Mohamed Alsaadi

Background: The most common cause of low back pain in children is muscle sprain and strain which can occur from carrying a heavy backpack or from activities. This study aimed to assess the relationship between school bag weight and back pain among female students in Dammam city.Methods: A total of 300 female students were included in this study both from east and west sectors of Dammam city, Saudi Arabia. Tools: Data were collected using (1) A structured questionnaire sheet including, socio-demographic data of the students, and close-ended questions about the school-bags as methods of carrying, (2) A weight scale that measured student’s body weight and weight of the school bags, (3) A self-report (Numeric pain rating scale) that assessed pain intensity. Univariate and Multivariate Statistical analysis was performed to test the relationship between the study variables.Results: A total of 288 school children (96.2% out of 300) were carrying bags of weight more than 15% of their body weight. Shoulder and neck pain were reported by 40% of the female students. Statistically there is a significant relationship was found between school bags weight and severity of shoulder pain (p = .042).Conclusion and recommendation: The weights of schoolbags of Dammam city intermediate female students were higher than the internationally acceptable standards. Ministry of Education should set standards to prevent and mange problems of carrying heavy school bags in the intermediate school.


Pain ◽  
2016 ◽  
Vol 157 (3) ◽  
pp. 546-551 ◽  
Author(s):  
Janelle E. Letzen ◽  
Jeff Boissoneault ◽  
Landrew S. Sevel ◽  
Michael E. Robinson

2017 ◽  
Vol 41 (S1) ◽  
pp. S311-S311
Author(s):  
D. Loureiro ◽  
A. Machado ◽  
T. Silva ◽  
T. Veigas ◽  
J. Cerejeira

IntroductionADHD is associated with psychopathic traits, both in the general population and in perpetrators, due to the impulsivity, but not the affective component of psychopathy.ObjectivesTo analyze this relationship among a sample of inmates from a high-security male prison, using an instrument that further divides the callous-unemotional factor of psychopathy into boldness and cruelty, and see if they relate to ADHD independently from the impulsivity/disinhibition.MethodsOne hundred and one subjects aged 18–65, with at least 4 years of formal education, were interviewed for socio-demographic data and completed the ASRS-v1.1 (Adult ADHD Self-Report Scale) and the TriPM (Triarchic Psychopathy Measure). Subjects were divided into ADHD positive or negative according to their score in the ASRS-v1.1, and then compared regarding TriPM score (total, disinhibition, boldness and cruelty) using Student's t-test. Linear regression was used to assess independency between the subscales of TriPM.ResultsSeventeen subjects scored positive for ADHD. They significantly differed from the non-ADHD group regarding all psychopathy scores (total, t = −5.03, P < 0.0001; disinhibition, t = −3.53, P = 0.0006; and cruelty, t = −4.96, P < 0.0001), except for boldness (t = 1.97, P = 0.005). The cruelty score is independent from boldness (R2 = 0.03) but not from the disinhibition score (R2 = 0.24). Disinhibition and boldness are also unrelated (R2 = 0.01).ConclusionsIn line with previous work, our study shows a strong association between ADHD and psychopathy, with both conditions sharing the disinhibition/impulsivity factor. Although ADHD subjects score higher for cruelty, this isn’t independent from disinhibition, and may be a result of them being more prone to admit to cruel behaviours, due to deficient response inhibition.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2020 ◽  
Vol 10 (2) ◽  
pp. 92-109
Author(s):  
Caroline S. Clauss-Ehlers

Background: Autobiographical narrative (i.e., the process through writing or storytelling where one recalls life experiences and their impact on identity) has been found to effectively help adolescents cope with a range of medical and psychological issues. Objective. : The current study addressed the overall preliminary research question: How does implementing an autobiographical narrative approach promote resilience, psychological well- being, and ethnic identity among adolescents? A secondary study aim was to explore how central the memories evoked by each workshop were to participant identity. The study’s third goal was to promote life skill development and self-awareness through participation in the autobiographical narrative intervention. Methods: The intervention incorporated a community-based participatory research (CBPR) framework in its partnership with a community centre in Northern England. The intervention consisted of an 8-week autobiographical program with youth participants from working and lower middle-class backgrounds. Socioeconomic status was operationalized by self-report on a demographic data sheet completed by participants. Results.: Analyses indicated that participants viewed the events discussed in the 8-week program as being more central to their lives after their participation. Maladaptive coping appeared to decrease after participation in the intervention. Conclusion: Results suggest interventions that incorporate an autobiographical narrative approach within a CBPR framework may promote positive outcomes among adolescents with limited economic resources.


2020 ◽  
Vol 21 (3) ◽  
pp. 281-322
Author(s):  
Vargha András ◽  
Zábó Virág ◽  
Török Regina ◽  
Oláh Attila

Elméleti háttér: A mentális egészség egyfajta jóllét biológiai, pszichológiai, társadalmi és spirituális szinten, ezen kívül pedig képesség a pozitív állapotok fenntartására és megélésére, amelyhez a hatékony megküzdés és savoring, valamint a reziliencia és a dinamikus önszabályozás jelenléte is társul. A pozitív pszichológia egyik feladata, hogy érvényes teszteket dolgozzon ki a mentális egészség mérésére. Cél: A Mentális Egészség Teszt (MET) legújabb változatának átfogó pszichometriai ellenőrzése. Módszer: Két, online módon lefolytatott kérdőíves keresztmetszeti vizsgálat. I. 1540 fő (391 férfi, 1149 nő; átlagéletkor 52,0 év, SD = 11,3 év) demográfiai, valamint testi és lelki egészségre vonatkozó kérdések mellett kitöltötte az alábbi kérdőíveket: MET, PERMA Kérdőív, Globális Jóllét Kérdőív, Diener-féle Virágzás skála, Rövidített Savoring Hit Kérdőív, Rövidített Pszichológiai Immunrendszer Kérdőív. II. 1083 fő (233 férfi, 847 nő; átlagéletkor 33,9 év, SD = 12,2 év) demográfiai, a vallásosságra, valamint a testi és lelki egészségre vonatkozó kérdések mellett kitöltötte a MET, Aspirációs Index, Rövidített Beck Depresszió, WHO Jól-Lét, Élettel való Elégedettség, valamint Életcél Kérdőíveket. Eredmények: Az I. mintán elvégzett feltáró faktoranalízis megerősítette a MET ötfaktoros szerkezetét 17 tétellel, s az ezt tesztelő konfirmatív faktoranalízis jó illeszkedésű modellt jelzett. A II. mintában ugyanezen a faktorstruktúrán elvégzett konfirmatív faktoranalízis kiváló illeszkedésű (RMSEA = 0,051; pClose = 0,408; CFI = 0,950; TLI = 0,936). Az öt skála Cronbach-a értékei mindkét vizsgálatban 0,70 felettiek, magas belső konzisztenciát mutatva. A diszkriminációs validitást igazolja, hogy minden skálának van egy minimum 44%-os olyan egyedi része, amelyet a többi négy skála nem fed le. A skálák tartalmi validitását a mentális egészség 10 tesztjével, speciális tesztkérdésekkel és szociodemográfiai mutatókkal sikerült igazolni. Fontos eredmény továbbá, hogy a jóllét pozitív irányú kapcsolatot mutat az anyagi helyzettel; az alkotó-végrehajtó hatékonyság a flow-val és az iskolázottsággal; az önreguláció és a reziliencia az életkorral; a savoring pedig a nőknél minden életkorban magasabb, mint a férfiaknál. Következtetés: a MET a jóllét, a savoring, az alkotó-végrehajtó hatékonyság, az önreguláció és a reziliencia konstruktumok megbízható és érvényes mérőeszközének tekinthető.Theoretical background: Beyond that mental health is related to biological, psychological, social, and spiritual well-being, it is a capacity to maintain and experience the positive conditions with effective coping, savoring, resilience and dynamic self-regulation skills. One of the most important responsibility of positive psychology is to construct scales measuring mental health. Aim: the purpose of this study is to present the psychometric characteristics of the new version of the Mental Health Test (MHT) based on five pillars. Method: Two online cross-sectional studies with self-report questionnaires. Study I: 1540 persons (391 men, 1149 women; mean age 52.0 years, SD = 11.3 years) filled in MHT, PERMA Profiler, Global Health, Diener's Flourishing Scale, Shortened Savoring and Shortened Psychological Immune Competence questionnaires along with questions about physical and psychological well-being and demographic data. Study II: 1083 persons (233 men, 847 women; mean age 33.9 years, SD = 12.2 years) filled in MHT, Aspiration Index, Shortened Beck Depression Inventory, WHO Well-Being Scale, Satisfaction with Life Scale, Purpose in Life Test, and Shortened Young Maladaptive Schema Questionnaire, along with questions about demographic data, religiosity, physical and mental health. Results: In Study I exploratory factor analysis identified the five-factor structure of MHT with 17 items, having also good fit measures in confirmative factor analysis. In Study II the five-factor model of the five subscales yielded excellent fit measures in confirmatory factor analysis (RMSEA = .051, pClose = .408, CFI = .950, TLI = .936). In both studies, Cronbach's a values of the five subscales (all above 0.70) indicated a high level of internal consistency. The discriminant validity is proven by the fact that each subscale had a minimum 44% part not covered by the set of other subscales. The content validity of the subscales was confirmed by ten tests about mental health, some special questions and socio-demographic indicators. Subscale of well-being showed a definite positive correlation with financial background. Creative and executing efficiency correlated with flow and education. We found also a positive correlation of self-regulation and resilience subscales with age, and women showed a higher level of savoring than men at all age levels. Conclusion: MHT can be considered a reliable and valid measurement tool for well-being, savoring, creative and executing efficiency, self-regulation and resilience dimensions of mental health.


2019 ◽  
Vol 28 (2) ◽  
pp. 274-284 ◽  
Author(s):  
Elizabeth Convery ◽  
Gitte Keidser ◽  
Louise Hickson ◽  
Carly Meyer

Purpose Hearing loss self-management refers to the knowledge and skills people use to manage the effects of hearing loss on all aspects of their daily lives. The purpose of this study was to investigate the relationship between self-reported hearing loss self-management and hearing aid benefit and satisfaction. Method Thirty-seven adults with hearing loss, all of whom were current users of bilateral hearing aids, participated in this observational study. The participants completed self-report inventories probing their hearing loss self-management and hearing aid benefit and satisfaction. Correlation analysis was used to investigate the relationship between individual domains of hearing loss self-management and hearing aid benefit and satisfaction. Results Participants who reported better self-management of the effects of their hearing loss on their emotional well-being and social participation were more likely to report less aided listening difficulty in noisy and reverberant environments and greater satisfaction with the effect of their hearing aids on their self-image. Participants who reported better self-management in the areas of adhering to treatment, participating in shared decision making, accessing services and resources, attending appointments, and monitoring for changes in their hearing and functional status were more likely to report greater satisfaction with the sound quality and performance of their hearing aids. Conclusion Study findings highlight the potential for using information about a patient's hearing loss self-management in different domains as part of clinical decision making and management planning.


GeroPsych ◽  
2019 ◽  
Vol 32 (1) ◽  
pp. 41-52
Author(s):  
Matthew C. Costello ◽  
Shane J. Sizemore ◽  
Kimberly E. O’Brien ◽  
Lydia K. Manning

Abstract. This study explores the relative value of both subjectively reported cognitive speed and gait speed in association with objectively derived cognitive speed. It also explores how these factors are affected by psychological and physical well-being. A group of 90 cognitively healthy older adults ( M = 73.38, SD = 8.06 years, range = 60–89 years) were tested in a three-task cognitive battery to determine objective cognitive speed as well as measures of gait speed, well-being, and subjective cognitive speed. Analyses indicated that gait speed was associated with objective cognitive speed to a greater degree than was subjective report, the latter being more closely related to well-being than to objective cognitive speed. These results were largely invariant across the 30-year age range of our older adult sample.


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