synder: inferring genomic orthologs from synteny maps
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AbstractOrtholog inference is a key step in understanding the evolution and function of a gene or other genomic feature. Yet often no similar sequence can be identified, or the true ortholog is hidden among false positives. A solution is to consider the sequence’s genomic context. We present the generic program,synder, for tracing features of interest between genomes based on a synteny map. This approach narrows genomic search-space independently of the sequence of the feature of interest. We illustrate the utility ofsynderby finding orthologs for theArabidopsis thaliana13-member gene family of Nuclear Factor YC transcription factor across the Brassicaceae clade.
2007 ◽
Vol 1
(2)
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pp. 166-175
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1994 ◽
Vol 269
(14)
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pp. 10341-10351
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2017 ◽
Vol 491
(3)
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pp. 642-648
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