Adaptive leader-follower role switching based on rhythm stability: Toward modeling of dynamic infant-caregiver interaction

2014 ◽  
Author(s):  
Ryo Iwaki ◽  
Hideyuki Takahashi ◽  
Minoru Asada
Keyword(s):  
Rhythm Stability

Levels of von Willebrand factor and ADAMTS13 determine clinical outcome after cardioversion for atrial fibrillation

2011 ◽  
Vol 105 (03) ◽  
pp. 435-443 ◽  
Author(s):  
Veronika Bruno ◽  
Rudolf Jarai ◽  
Susanne Gruber ◽  
Thomas Höchtl ◽  
Ivan Brozovic ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Von Willebrand Factor ◽  
Platelet Adhesion ◽  
Independent Predictor ◽  
Thrombus Formation ◽  
Critical Role ◽  
Inverse Correlation ◽  
Von Willebrand ◽  
Rhythm Stability ◽  
Willebrand Factor

SummaryVon Willebrand factor (vWF) plays an essential role in platelet adhesion and thrombus formation. Patients with atrial fibrillation (AF) exhibit higher plasma vWF and lower ADAMTS13 antigen levels compared to controls. Little is known about vWF and ADAMTS13 in AF patients treated with cardioversion (CV). Thus we investigated the alterations of plasma vWF and ADAMTS13 after CV and evaluated the predictive value of these parameters for recurrence of AF. In this observational study we determined plasma levels of vWF and ADAMTS13 in 77 patients before and immediately after CV, as well as 24 hours (h) and six weeks thereafter, by means of commercially available assays. The vWF/ ADAMTS13-ratio was significantly elevated immediately after CV (p=0.02) and 24 h after CV (p=0.002) as compared to baseline levels. ADAMTS13, 24 h after CV, exhibited a significant association with recurrence of AF (HR: 0.97; p=0.037). Accordingly, tertiles of ADAMTS13 showed a stepwise inverse correlation with the risk of recurrent AF (HR: 0.50; p=0.009). After adjustment for confounders, ADAMTS13 remained significant as an independent predictor of recurrent AF (HR: 0.61; p=0.047). Similarly, the vWF/ADAMTS13-ratio, 24 h after CV, was associated with rhythm stability and remained an independent predictor of recurrent AF (HR: 1.88; p=0.028). The regulation of vWF and its cleaving protease ADAMTS13 after CV might play a critical role in producing a pro-thrombotic milieu immediately after CV for AF. Since ADAMTS13 plasma concentration and the vWF/ADAMTS13-ratio are independently associated with rhythm stability, these indexes might be used for prediction of recurrence of AF.

MONOPHASIC ACTION POTENTIAL AND SINUS RHYTHM STABILITY AFTER CONVERSION OF ATRIAL FIBRILLATION

2009 ◽  
Vol 190 (1-6) ◽  
pp. 381-387 ◽  
Author(s):  
S. Bertil Olsson ◽  
Simion Cotoi ◽  
E. Varnauskas
Keyword(s):  
Atrial Fibrillation ◽  
Action Potential ◽  
Sinus Rhythm ◽  
Monophasic Action Potential ◽  
Rhythm Stability

The associations between illness perceptions and social rhythm stability on mood symptoms among patients with bipolar disorder

2020 ◽  
Vol 273 ◽  
pp. 517-523
Author(s):  
Esther Ching-Lan Lin ◽  
Marc J. Weintraub ◽  
David J. Miklowitz ◽  
Po-See Chen ◽  
Shih-Kai Lee ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Illness Perceptions ◽  
Mood Symptoms ◽  
Social Rhythm ◽  
Rhythm Stability

Vorhofflimmern: Wie wichtig ist der Erhalt des Sinusrhythmus?

2020 ◽  
Vol 145 (08) ◽  
pp. 543-549
Author(s):  
Christian Meyer ◽  
Andreas Metzner ◽  
Paulus Kirchhof
Keyword(s):  
Quality Of Life ◽  
Antiarrhythmic Drugs ◽  
Pulmonary Veins ◽  
Left Ventricular ◽  
Rhythm Control ◽  
Af Ablation ◽  
Stroke Risk Factors ◽  
Control Therapy ◽  
Rhythm Stability

AbstractRhythm control therapy, comprising antiarrhythmic drugs, cardioversion, and AF ablation, is an important component in the management of patients with atrial fibrillation (AF). Catheter ablation for AF, mainly targeting isolation of the pulmonary veins (AF ablation), has markedly improved the effectiveness of rhythm control therapy. Rhythm control improves symptoms and quality of life in patients with symptomatic AF. AF ablation maintains sinus rhythm more effectively than antiarrhythmic drug therapy. Antiarrhythmic drugs remain effective after AF ablation, underpinning the synergistic mechanisms of action of AF ablation and antiarrhythmic drugs. Different lifestyle interventions might additionally improve symptoms and rhythm stability in patients with AF. AF ablation appears to improve left ventricular function in a subset of patients. Summarized, rhythm control therapy in patients with symptomatic AF is safe and improves quality of life, including elderly patients with stroke risk factors. Further studies are needed to determine whether rhythm control therapy reduces AF-related complications while improving patient outcome with regard to prognosis.

scholarly journals Weight loss in conservative treatment of obesity in women is associated with physical activity and circadian phenotype: a longitudinal observational study

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Eva Fárková ◽  
Jakub Schneider ◽  
Michal Šmotek ◽  
Eduard Bakštein ◽  
Jitka Herlesová ◽  
...  
Keyword(s):  
Physical Activity ◽  
Weight Loss ◽  
Conservative Treatment ◽  
Observational Study ◽  
Direct Relationship ◽  
Close Connection ◽  
Longitudinal Observational Study ◽  
Treatment Of Obesity ◽  
Rhythm Stability ◽  
Main Factor

Abstract Introduction The study investigates the association between circadian phenotype (CP), its stability (interdaily stability - IS) and physical activity (PA) in a weight loss (WL) programme. Methods Seventy-five women in WL conservative treatment (BMI ≥ 25 kg/m2) were measured (for about 3 months in between 2016 and 2018) by actigraphy. Results We observed a difference in time of acrophase (p = 0.049), but no difference in IS (p = 0.533) between women who lost and did not lose weight. There was a difference in PA (mesor) between groups of women who lost weight compared to those who gained weight (p = 0.007). There was a relationship between IS and PA parametres mesor: p0.001; and the most active 10 h of a day (M10): p < 0.001 - the more stable were women in their rhythm, the more PA they have. Besides confirming a relationship between PA and WL, we also found a relation between WL and CP based on acrophase. Although no direct relationship was found for the indicators of rhythm stability (IS), they can be considered very important variables because of their close connection to PA – a main factor that contributes to the success of the WL programme. Discussion According to the results of the study, screening of the CP and its stability may be beneficial in the creation of an individualized WL plan.

scholarly journals Chronic ethanol attenuates circadian photic phase resetting and alters nocturnal activity patterns in the hamster

2009 ◽  
Vol 297 (3) ◽  
pp. R729-R737 ◽  
Author(s):  
Christina L. Ruby ◽  
Allison J. Brager ◽  
Marc A. DePaul ◽  
Rebecca A. Prosser ◽  
J. David Glass
Keyword(s):  
Activity Patterns ◽  
Dark Phase ◽  
Disruptive Effect ◽  
Phase Resetting ◽  
Photic Entrainment ◽  
Light Intensities ◽  
Acute Ethanol ◽  
Activity Onset ◽  
Rhythm Stability ◽  
Withdrawal Effects

Acute ethanol (EtOH) administration impairs circadian clock phase resetting, suggesting a mode for the disruptive effect of alcohol abuse on human circadian rhythms. Here, we extend this research by characterizing the chronobiological effects of chronic alcohol consumption. First, daily profiles of EtOH were measured in the suprachiasmatic nucleus (SCN) and subcutaneously using microdialysis in hamsters drinking EtOH. In both cases, EtOH peaked near lights-off and declined throughout the dark-phase to low day-time levels. Drinking bouts preceded EtOH peaks by ∼20 min. Second, hamsters chronically drinking EtOH received a light pulse during the late dark phase [Zeitgeber time (ZT) 18.5] to induce photic phase advances. Water controls had shifts of 1.2 ± 0.2 h, whereas those drinking 10% and 20% EtOH had much reduced shifts (0.5 ± 0.1 and 0.3 ± 0.1 h, respectively; P < 0.001 vs. controls). Third, incremental decreases in light intensity (270 lux to 0.5 lux) were used to explore chronic EtOH effects on photic entrainment and rhythm stability. Activity onset was unaffected by 20% EtOH at all light intensities. Conversely, the 24-h pattern of activity bouts was disrupted by EtOH under all light intensities. Finally, replacement of chronic EtOH with water was used to examine withdrawal effects. Water controls had photic phase advances of 1.1 ± 0.3 h, while hamsters deprived of EtOH for 2–3 days showed enhanced shifts (2.1 ± 0.3 h; P < 0.05 vs. controls). Thus, in chronically drinking hamsters, brain EtOH levels are sufficient to inhibit photic phase resetting and disrupt circadian activity. Chronic EtOH did not impair photic entrainment; however, its replacement with water potentiated photic phase resetting.

scholarly journals NT-ProBNP Predicts Rhythm Stability After Cardioversion of Lone Atrial Fibrillation

2008 ◽  
Vol 72 (6) ◽  
pp. 921-925 ◽  
Author(s):  
Helge Möllmann ◽  
Michael Weber ◽  
Albrecht Elsässer ◽  
Holger Nef ◽  
Thorsten Dill ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Lone Atrial Fibrillation ◽  
Rhythm Stability

Social rhythm stability following late-life spousal bereavement: associations with depression and sleep impairment

1996 ◽  
Vol 62 (2) ◽  
pp. 161-169 ◽  
Author(s):  
Lincoln F. Brown ◽  
Charles F. Reynolds ◽  
Timothy H. Monk ◽  
Holly G. Prigerson ◽  
Mary Amanda Dew ◽  
...  
Keyword(s):  
Late Life ◽  
Spousal Bereavement ◽  
Sleep Impairment ◽  
Social Rhythm ◽  
Rhythm Stability

scholarly journals Uncovering complexity details in actigraphy patterns to differentiate the depressed from the non-depressed

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sandip Varkey George ◽  
Yoram K Kunkels ◽  
Sanne Booij ◽  
Marieke Wichers
Keyword(s):  
Physical Activity ◽  
Activity Patterns ◽  
Activity Levels ◽  
Complexity Measures ◽  
Depression Status ◽  
Depressed Group ◽  
Measured Activity ◽  
Data Points ◽  
Objectively Measured ◽  
Rhythm Stability

AbstractWhile the negative association between physical activity and depression has been well established, it is unclear what precise characteristics of physical activity patterns explain this association. Complexity measures may identify previously unexplored aspects of objectively measured activity patterns, such as the extent to which individuals show repetitive periods of physical activity and the diversity in durations of such repetitive activity patterns. We compared the complexity levels of actigraphy data gathered over 4 weeks ($$\sim 40000$$ ∼ 40000 data points each) for every individual, from non-depressed ($$n=25$$ n = 25 ) and depressed ($$n=21$$ n = 21 ) groups using recurrence plots. Significantly lower levels of complexity were detected in the actigraphy data from the depressed group as compared to non-depressed controls, both in terms of lower mean durations of periods of recurrent physical activity and less diversity in the duration of these periods. Further, diagnosis of depression was not significantly associated with mean activity levels or measures of circadian rhythm stability, and predicted depression status better than these.

scholarly journals Dopaminergic modulation of locomotor network activity in the neonatal mouse spinal cord

2015 ◽  
Vol 113 (7) ◽  
pp. 2500-2510 ◽  
Author(s):  
Simon A. Sharples ◽  
Jennifer M. Humphreys ◽  
A. Marley Jensen ◽  
Sunny Dhoopar ◽  
Nicole Delaloye ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Network Activity ◽  
Receptor Subtypes ◽  
Inhibitory Effects ◽  
Locomotor Rhythm ◽  
Bath Application ◽  
Locomotor Rhythms ◽  
The Stability ◽  
Rhythm Stability ◽  
Dose Dependent

Dopamine is now well established as a modulator of locomotor rhythms in a variety of developing and adult vertebrates. However, in mice, while all five dopamine receptor subtypes are present in the spinal cord, it is unclear which receptor subtypes modulate the rhythm. Dopamine receptors can be grouped into two families—the D1/5 receptor group and the D2/3/4 group, which have excitatory and inhibitory effects, respectively. Our data suggest that dopamine exerts contrasting dose-dependent modulatory effects via the two receptor families. Our data show that administration of dopamine at concentrations >35 μM slowed and increased the regularity of a locomotor rhythm evoked by bath application of 5-hydroxytryptamine (5-HT) and N-methyl-d(l)-aspartic acid (NMA). This effect was independent of the baseline frequency of the rhythm that was manipulated by altering the NMA concentration. We next examined the contribution of the D1- and D2-like receptor families on the rhythm. Our data suggest that the D1-like receptor contributes to enhancement of the stability of the rhythm. Overall, the D2-like family had a pronounced slowing effect on the rhythm; however, quinpirole, the D2-like agonist, also enhanced rhythm stability. These data indicate a receptor-dependent delegation of the modulatory effects of dopamine on the spinal locomotor pattern generator.

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