A Power-efficient Bidirectional Potentiostat-based Readout IC for Wide-range Electrochemical Sensing

Author(s):  
Jui-Hsiang Tsai ◽  
Yi-Chia Chen ◽  
Yu-Te Liao
2021 ◽  
Vol 11 (3) ◽  
pp. 31
Author(s):  
Anindita Paul ◽  
Mario Renteria-Pinon ◽  
Jaime Ramirez-Angulo ◽  
Ricardo Bolaños-Pérez ◽  
Héctor Vázquez-Leal ◽  
...  

An approach to implement single-ended power-efficient static class-AB Miller op-amps with symmetrical and significantly enhanced slew-rate and accurately controlled output quiescent current is introduced. The proposed op-amp can drive a wide range of resistive and capacitive loads. The output positive and negative currents can be much higher than the total op-amp quiescent current. The enhanced performance is achieved by utilizing a simple low-power auxiliary amplifier with resistive local common-mode feedback that increases the quiescent power dissipation by less than 10%. The proposed class AB op-amp is characterized by significantly enhanced large-signal dynamic, static current efficiency, and small-signal figures of merits. The dynamic current efficiency is 15.6 higher, the static current efficiency is 8.9 times higher, and the small-signal figure of merit is 2.3 times higher than the conventional class-A op-amp. A global figure of merit that determines an op-amp’s ultimate speed is 6.33 times higher than the conventional class A op-amp.


Author(s):  
Totka Dodevska ◽  
Dobrin Hadzhiev ◽  
Ivan Shterev ◽  
Yanna Lazarova

Recently, the development of eco-friendly, cost-effective and reliable methods for synthesis of metal nanoparticles has drawn a considerable attention. The so-called green synthesis, using mild reaction conditions and natural resources as plant extracts and microorganisms, has established as a convenient, sustainable, cheap and environmentally safe approach for synthesis of a wide range of nanomaterials. Over the past decade, biosynthesis is regarded as an important tool for reducing the harmful effects of traditional nanoparticle synthesis methods commonly used in laboratories and industry. This review emphasizes the significance of biosynthesized metal nanoparticles in the field of electrochemical sensing. There is increasing evidence that green synthesis of nanoparticles provides a new direction in designing of cost-effective, highly sensitive and selective electrode-catalysts applicable in food, clinical and environmental analysis. The article is based on 157 references and provided a detailed overview on the main approaches for green synthesis of metal nanoparticles and their applications in designing of electrochemical sensor devices. Important operational characteristics including sensitivity, dynamic range, limit of detection, as well as data on stability and reproducibility of sensors have also been covered. Keywords: biosynthesis; green synthesis; nanomaterials; nanotechnology; modified electrodes


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sangam Srikanth ◽  
Sohan Dudala ◽  
U. S. Jayapiriya ◽  
J. Murali Mohan ◽  
Sushil Raut ◽  
...  

AbstractControlled, stable and uniform temperature environment with quick response are crucial needs for many lab-on-chip (LOC) applications requiring thermal management. Laser Induced Graphene (LIG) heater is one such mechanism capable of maintaining a wide range of steady state temperature. LIG heaters are thin, flexible, and inexpensive and can be fabricated easily in different geometric configurations. In this perspective, herein, the electro-thermal performance of the LIG heater has been examined for different laser power values and scanning speeds. The experimented laser ablated patterns exhibited varying electrical conductivity corresponding to different combinations of power and speed of the laser. The conductivity of the pattern can be tailored by tuning the parameters which exhibit, a wide range of temperatures making them suitable for diverse lab-on-chip applications. A maximum temperature of 589 °C was observed for a combination of 15% laser power and 5.5% scanning speed. A LOC platform was realized by integrating the developed LIG heaters with a droplet-based microfluidic device. The performance of this LOC platform was analyzed for effective use of LIG heaters to synthesize Gold nanoparticles (GNP). Finally, the functionality of the synthesized GNPs was validated by utilizing them as catalyst in enzymatic glucose biofuel cell and in electrochemical applications.


2021 ◽  
Author(s):  
Ian Seymour ◽  
Tarun Narayan ◽  
Niamh Creedon ◽  
Kathleen Kennedy ◽  
Aidan Murphy ◽  
...  

Global food production needs to increase in order to meet the demands of an ever growing population. As resources are finite, the most feasible way to meet this demand is to minimize losses and improving efficiency. Regular monitoring of factors like animal health, soil and water quality for example, can ensure that the resources are being used to their maximum efficiency. Existing monitoring techniques however have limitations, such as portability, turnaround time and requirement for additional reagents. In this work, we explore the use of micro and nano scale electrode devices, for the development of electrochemical sensing platform to digitalize a wide range of applications within the Agri-food sector. With this platform, we demonstrate the direct electrochemical detection of pesticides, specifically clothianidin and imidacloprid with detection limits of 0.22 ng/mL and 2.14 ng/mL respectively, and nitrates with a detection limit of 0.2 µM. In addition, interdigitated electrode structures also enable an in-situ pH control technique to mitigate pH as an interference and modify analyte response. This technique is applied to the analysis of monochloramine, a common water disinfectant. Concerning biosensing, the sensors are modified with biomolecular probes for the detection of both bovine viral diarrhea virus particles and antibodies, over a range of 1 ng/mL to 10 µg/mL. Finally, a portable analogue front end electronic reader is developed to allow portable sensing, with control and readout undertaken using a smart phone application. Finally, the sensor chip platform is integrated with these electronics to provide a fully functional end-to-end smart sensor system compatible with emerging AgriFood digital decision support tools.


2021 ◽  
Author(s):  
Ian Seymour ◽  
Tarun Narayan ◽  
Niamh Creedon ◽  
Kathleen Kennedy ◽  
Aidan Murphy ◽  
...  

Global food production needs to increase in order to meet the demands of an ever growing population. As resources are finite, the most feasible way to meet this demand is to minimize losses and improving efficiency. Regular monitoring of factors like animal health, soil and water quality for example, can ensure that the resources are being used to their maximum efficiency. Existing monitoring techniques however have limitations, such as portability, turnaround time and requirement for additional reagents. In this work, we explore the use of micro and nano scale electrode devices, for the development of electrochemical sensing platform to digitalize a wide range of applications within the Agri-food sector. With this platform, we demonstrate the direct electrochemical detection of pesticides, specifically clothianidin and imidacloprid with detection limits of 0.22 ng/mL and 2.14 ng/mL respectively, and nitrates with a detection limit of 0.2 µM. In addition, interdigitated electrode structures also enable an in-situ pH control technique to mitigate pH as an interference and modify analyte response. This technique is applied to the analysis of monochloramine, a common water disinfectant. Concerning biosensing, the sensors are modified with biomolecular probes for the detection of both bovine viral diarrhea virus particles and antibodies, over a range of 1 ng/mL to 10 µg/mL. Finally, a portable analogue front end electronic reader is developed to allow portable sensing, with control and readout undertaken using a smart phone application. Finally, the sensor chip platform is integrated with these electronics to provide a fully functional end-to-end smart sensor system compatible with emerging AgriFood digital decision support tools.


2021 ◽  
Author(s):  
Haleh Vahedi Vahedi

A programmable wide-range PLL has been designed that can provide 100-MHz to 1-GHz rail-to-rail digital clock signal from a 50-MHz reference clock. The architecture is appropriate for low-power design and is also power-efficient. The system is robust against temperature changes so that the stability of the system is guaranteed. Because of the differential configuration of the sub-blocks and using a voltage-controlled oscillator with a 1Ow. gain and a linear transfer function the system has an acceptable noise rejection.


This work figures the conceptual background of impedimetric measurements. Impedance measurement is a convenient approach for exploring the change in electrical behavior of diverse materials. An overview of in practice impedance analysis on CHI660D electrochemical work station is presented. Detection of microorganism causing foodborne diseases using IDE and other methods, toxic metal ion quantification, environment pollutant monitoring are described applications in this work. This work also reviewed the noticeable development in impedance measurement devices based on AD5933 such as bio-impedance measurement and explosive material detection. Biological signals are detected by transducing them into electrical analogy, detection of which is not a big issue. The main challenges are to convert biological signal into electrical information. Electrochemical sensors present captivating techniques to determine the content of sample under test. Electrochemical sensing platforms come up with an appealing methodology to interpret the concentration of biological sample as these sensors directly translate biological information to an electronic one. Huge amount of sensing platforms and corresponding devices has been developed. EIS is a rapid and easily computerized technique used to characterize biomolecules, inorganic materials, having a wide range of applications. The measured impedance spectra are generally fitted to an analogous electrical circuit model which constitutes an electrical documentation of the SUT by disclosing its behavior and properties. Quick, highly selective/specific and sensitive techniques to quantify biological and biochemical molecules and other target species are of great importance in biomedical and biotechnological application. Recent developments trends for handy, portable, fast and precise impedance analyzer is discussed. AD5933 evolution kit is reviewed.


2014 ◽  
Vol 6 (5) ◽  
pp. 3394-3405 ◽  
Author(s):  
Xianwen Mao ◽  
Xiaoqing Yang ◽  
Gregory C. Rutledge ◽  
T. Alan Hatton

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