Societal preferences for the conservation of traditional pig breeds and their agroecosystems: Addressing preference heterogeneity and protest responses through deterministic allocation and scale‐extended models

Leptin receptor is one of the components of the system of regulating energy homeostasis of the organism. Leptin receptor gene (LEPR) polymorphism is associated with pig carcass index of the content of intramus- cular fat in its valuable parts, which is particularly important when assessing the quality of their carcasses for processing. Intramuscular fat is associated with meat fl avor characteristics and partly determines its tenderness, juiciness, and other parameters. Aim. To analyze LEPR gene (SNP NM001024587.1, p. 1987 C > T) polymor- phism in populations of various pig breeds and to establish its relationship with the quality of both meat and fat of pigs of Large White breed of Ukrainian breeding. Methods. Genetic-population analysis of nine pig breeds, associative analysis on the search connection of LEPR gene polymorphism with quality of both meat and fat of pigs of Large White breed of Ukrainian breeding. LEPR locus genotyping was performed by High Resolution Melting (HRM). Results. All the studied breeds are characterized by polymorphism of the leptin receptor gene (SNP NM001024587.1, p. 1987 C > T), signifi cant breed specifi city in the distribution of frequencies of alleles was established. Statistically confi rmed effect (p < 0.05) of genotypes LEPR on the content of intramuscular fat, total dry matter and moisture in the meat, as well as the moisture content in the back fat of pigs of Ukrainian Large White breed was revealed. Higher content of intramuscular fat was found in the animals with genotype TT, while a smaller amount of intramuscular fat and more moisture in fat was revealed in heterozygotes. Conclusions. Genetic marker LEPR SNP NM001024587.1, p. 1987 C > T can be used in the marker-assisted selection to predict and improve the performance quality of the meat of pigs of Large White breed of the Ukrainian breeding. These results suggest that porcine leptin receptor gene controls the quality of fat comp- lex – inside muscles and in the dorsal part of the carcass.

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Integrated analysis of non-coding RNA and mRNA expression profiles of 2 pig breeds differing in muscle traits

Journal of Animal Science ◽

10.2527/jas2016.0867 ◽

2017 ◽

Vol 95 (3) ◽

pp. 1092 ◽

Cited By ~ 4

Author(s):

J. Sun ◽

M. Xie ◽

Z. Huang ◽

H. Li ◽

T. chen ◽

...

Keyword(s):

Mrna Expression ◽

Expression Profiles ◽

Integrated Analysis ◽

Pig Breeds ◽

Non Coding Rna

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Beyond External Constraints on Expropriation of Minority Investors: Preference Heterogeneity, Locus of Control and Firm Valuation

SSRN Electronic Journal ◽

10.2139/ssrn.2247418 ◽

2013 ◽

Author(s):

Katarina Sikavica ◽

Esther Kessler

Keyword(s):

Locus Of Control ◽

Firm Valuation ◽

Preference Heterogeneity ◽

External Constraints

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Exploring Smallholder Farmers’ Preferences for Climate-Smart Seed Innovations: Empirical Evidence from Southern Ethiopia

Sustainability ◽

10.3390/su13052786 ◽

2021 ◽

Vol 13 (5) ◽

pp. 2786

Author(s):

Shimelis Araya Geda ◽

Rainer Kühl

Keyword(s):

Smallholder Farmers ◽

Preference Heterogeneity ◽

Southern Ethiopia ◽

Significant Preference ◽

Experiment Data ◽

Breeding Programs ◽

Drought Tolerant ◽

The Face ◽

Mnl Model ◽

Participatory Research Methods

Rapid plant breeding is essential to overcome low productivity problems in the face of climatic challenges. Despite considerable efforts to improve breeding practices in Ethiopia, increasing varietal release does not necessarily imply that farmers have access to innovative varietal choices. Prior research did not adequately address whether varietal attributes are compatible with farmers’ preferences in harsh environmental conditions. With an agricultural policy mainly aiming to achieve productivity maximization, existing breeding programs prioritize varietal development based on yield superiority. Against this background, we estimated a multinomial logit (MNL) model based on choice-experiment data from 167 bean growers in southern Ethiopia to explore whether farmers’ attribute preferences significantly diverge from those of breeders’ priorities. Four important bean attributes identified through participatory research methods were used. The results demonstrate that farmers have a higher propensity toward drought-tolerant capability than any of the attributes considered. The model estimates further show the existence of significant preference heterogeneity across farmers. These findings provide important insight to design breeding profiles compatible with specific producer segments. We suggest demand-driven breeding innovations and dissemination strategies in order to accelerate the adoption of climate-smart and higher-yielding bean innovations that contribute to achieve the national and global sustainability goals in Ethiopia.

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Transcriptomic Profiling of Skeletal Muscle Reveals Candidate Genes Influencing Muscle Growth and Associated Lipid Composition in Portuguese Local Pig Breeds

Animals ◽

10.3390/ani11051423 ◽

2021 ◽

Vol 11 (5) ◽

pp. 1423

Author(s):

André Albuquerque ◽

Cristina Óvilo ◽

Yolanda Núñez ◽

Rita Benítez ◽

Adrián López-Garcia ◽

...

Keyword(s):

Candidate Genes ◽

Muscle Growth ◽

Rna Seq ◽

Next Generation Sequencing Technology ◽

Pig Breeds ◽

Nfkb Activation ◽

Main Gene ◽

Slow Type ◽

Longissimus Lumborum ◽

Generation Sequencing

Gene expression is one of the main factors to influence meat quality by modulating fatty acid metabolism, composition, and deposition rates in muscle tissue. This study aimed to explore the transcriptomics of the Longissimus lumborum muscle in two local pig breeds with distinct genetic background using next-generation sequencing technology and Real-Time qPCR. RNA-seq yielded 49 differentially expressed genes between breeds, 34 overexpressed in the Alentejano (AL) and 15 in the Bísaro (BI) breed. Specific slow type myosin heavy chain components were associated with AL (MYH7) and BI (MYH3) pigs, while an overexpression of MAP3K14 in AL may be associated with their lower loin proportion, induced insulin resistance, and increased inflammatory response via NFkB activation. Overexpression of RUFY1 in AL pigs may explain the higher intramuscular (IMF) content via higher GLUT4 recruitment and consequently higher glucose uptake that can be stored as fat. Several candidate genes for lipid metabolism, excluded in the RNA-seq analysis due to low counts, such as ACLY, ADIPOQ, ELOVL6, LEP and ME1 were identified by qPCR as main gene factors defining the processes that influence meat composition and quality. These results agree with the fatter profile of the AL pig breed and adiponectin resistance can be postulated as responsible for the overexpression of MAP3K14′s coding product NIK, failing to restore insulin sensitivity.

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Function of the Porcine TRPC1 Gene in Myogenesis and Muscle Growth

Cells ◽

10.3390/cells10010147 ◽

2021 ◽

Vol 10 (1) ◽

pp. 147

Author(s):

Yu Fu ◽

Peng Shang ◽

Bo Zhang ◽

Xiaolong Tian ◽

Ruixue Nie ◽

...

Keyword(s):

Transient Receptor Potential ◽

Growth Traits ◽

Expression Profiles ◽

Muscle Growth ◽

Receptor Potential ◽

Transient Receptor Potential Channel ◽

Nucleotide Polymorphisms ◽

Pig Breeds ◽

Muscle Tissues ◽

Transient Receptor

In animals, muscle growth is a quantitative trait controlled by multiple genes. Previously, we showed that the transient receptor potential channel 1 (TRPC1) gene was differentially expressed in muscle tissues between pig breeds with divergent growth traits base on RNA-seq. Here, we characterized TRPC1 expression profiles in different tissues and pig breeds and showed that TRPC1 was highly expressed in the muscle. We found two single nucleotide polymorphisms (SNPs) (C-1763T and C-1604T) in TRPC1 that could affect the promoter region activity and regulate pig growth rate. Functionally, we used RNAi and overexpression to illustrate that TRPC1 promotes myoblast proliferation, migration, differentiation, fusion, and muscle hypertrophy while inhibiting muscle degradation. These processes may be mediated by the activation of Wnt signaling pathways. Altogether, our results revealed that TRPC1 might promote muscle growth and development and plays a key role in Wnt-mediated myogenesis.

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How does the preference heterogeneity affect the elderly's evaluation of bus accessibility? Evidence from Guangzhou, China

Journal of Transport & Health ◽

10.1016/j.jth.2021.101094 ◽

2021 ◽

Vol 22 ◽

pp. 101094

Author(s):

Jianrong Liu ◽

Shaopeng Zhong ◽

Yaqing Huang ◽

Zhong Wang

Keyword(s):

Preference Heterogeneity

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Job preferences of undergraduate pharmacy students in China: a discrete choice experiment

Human Resources for Health ◽

10.1186/s12960-021-00626-8 ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Ping Liu ◽

Shimeng Liu ◽

Tiantian Gong ◽

Quan Li ◽

Gang Chen ◽

...

Keyword(s):

Discrete Choice Experiment ◽

Discrete Choice ◽

Rural Areas ◽

Choice Experiment ◽

Job Characteristics ◽

Pharmacy Students ◽

Preference Heterogeneity ◽

Short Supply ◽

Job Preferences ◽

Open Management

Abstract Background Pharmacists are a crucial part of the health workforce and play an important role in achieving universal health coverage. In China, pharmaceutical human resources are in short supply, and the distribution is unequal. This study aimed to identify the key job characteristics that influence the job preferences of undergraduate pharmacy students and to elicit the relative importance of different job characteristics to shed light on future policy interventions. Methods A discrete choice experiment was conducted to assess the job preferences of undergraduate pharmacy students from 6 provinces in mainland China. A face-to-face interview was used to collect data. Conditional logit and mixed logit models were used to analyse data, and the final model was chosen according to the model fit statistics. A series of policy simulations was also conducted. Results In total, 581 respondents completed the questionnaire, and 500 respondents who passed the internal consistency test were analysed. All attributes were statistically significant except for open management. Monthly income and work location were most important to respondents, followed by work unit (which refers to the nature of the workplace) and years to promotion. There was preference heterogeneity among respondents, e.g., male students preferred open management, and female students preferred jobs in public institutions. Furthermore, students with an urban background or from a single-child family placed higher value on a job in the city compared to their counterparts. Conclusion The heterogeneity of attributes showed the complexity of job preferences. Both monetary and nonmonetary job characteristics significantly influenced the job preferences of pharmacy students in China. A more effective policy intervention to attract graduates to work in rural areas should consider both incentives on the job itself and the background of pharmacy school graduates.

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