Topiramate for the Prevention of Primary Headache Associated With Sexual Activity: The Third and Fourth Case Reports

2020 ◽  
Vol 60 (8) ◽  
pp. 1800-1802
Author(s):  
Randolph W. Evans
Keyword(s):  
Sexual Activity ◽  
Case Reports ◽  
Primary Headache ◽  
The Third ◽  
Fourth Case

The impact of sexual activity on idiopathic headaches: An observational study

Cephalalgia ◽  
2013 ◽  
Vol 33 (6) ◽  
pp. 384-389 ◽  
Author(s):  
Anke Hambach ◽  
Stefan Evers ◽  
Oliver Summ ◽  
Ingo W Husstedt ◽  
Achim Frese
Keyword(s):  
Observational Study ◽  
Cluster Headache ◽  
Sexual Activity ◽  
Case Reports ◽  
Primary Headache ◽  
Complete Relief ◽  
Headache Attack ◽  
Cluster Headache Attack ◽  
The Impact ◽  
Headache Patients

Background Headache associated with sexual activity is a well-known primary headache disorder. In contrast, some case reports in the literature suggest that sexual activity during a migraine or cluster headache attack might relieve the pain in at least some patients. We performed an observational study among patients of a tertiary headache clinic. Methods A questionnaire was sent to 800 unselected migraine patients and 200 unselected cluster headache patients. We asked for experience with sexual activity during a headache attack and its impact on headache intensity. The survey was strictly and completely anonymous. Results In total, 38% of the migraine patients and 48% of the patients with cluster headache responded. In migraine, 34% of the patients had experience with sexual activity during an attack; out of these patients, 60% reported an improvement of their migraine attack (70% of them reported moderate to complete relief) and 33% reported worsening. In cluster headache, 31% of the patients had experience with sexual activity during an attack; out of these patients, 37% reported an improvement of their cluster headache attack (91% of them reported moderate to complete relief) and 50% reported worsening. Some patients, in particular male migraine patients, even used sexual activity as a therapeutic tool. Conclusions The majority of patients with migraine or cluster headache do not have sexual activity during headache attacks. Our data suggest, however, that sexual activity can lead to partial or complete relief of headache in some migraine and a few cluster headache patients.

Orgasmic migraine aura: Report of two cases

Cephalalgia ◽  
2018 ◽  
Vol 39 (1) ◽  
pp. 153-156 ◽  
Author(s):  
Heather Angus-Leppan ◽  
Alice Caulfield
Keyword(s):  
Subarachnoid Haemorrhage ◽  
Sexual Activity ◽  
Case Reports ◽  
Primary Headache ◽  
Neurological Symptoms ◽  
Thunderclap Headache ◽  
Reversible Cerebral Vasoconstriction Syndrome ◽  
Migraine Aura ◽  
Cerebral Vasoconstriction ◽  
Underlying Causes

Background Paroxysmal neurological symptoms occurring with sex cause considerable anxiety and sometimes have a serious cause. Thunderclap headache is the most well-known and requires urgent investigation at first presentation for subarachnoid haemorrhage and other significant pathologies. After exclusion of underlying causes, many prove to be primary headache associated with sexual activity. Orgasmic migraine aura without headache is not currently recognised as a clinical entity. Case reports We report two patients with acephalgic orgasmic neurological symptoms fulfilling the criteria for migraine aura. Conclusions The incidence of acephalgic orgasmic migraine aura is unknown. It should be considered as part of the differential of paroxysmal sex-related neurological symptoms, and clinically differentiated from fixed deficits, reversible cerebral vasoconstriction syndrome and post-orgasmic illness syndrome.

scholarly journals Unfit for Work, Fit for Firearm or driving license - Is that Possible?

2019 ◽  
Vol 7 (17) ◽  
pp. 2864-2867
Author(s):  
Hrvoje Lalić
Keyword(s):  
Psychiatric Disorders ◽  
Occupational Medicine ◽  
Case Reports ◽  
Work Capacity ◽  
Chronic Alcoholic ◽  
Driving License ◽  
The Third ◽  
Life Threatening ◽  
Car Driving ◽  
Single Worker

BACKGROUND: Psychiatric disorders are not compatible with carrying firearms or with driving a car. Persons with such disorders are often not employed and are persistent in demanding invalidity pensions, but some of them also insist on holding on to the mentioned licenses. In such cases, where persons are already in possession of firearms and driving licences, it never occurs to them, that they should surrender their permits back. AIM Pointing to the importance of OM controlling firearm/car driving licenses. CASE REPORTS: This paper discusses the problem of three cases that should be widely recognised as it is potentially life-threatening to other people. The first is the case of a war veteran in retirement with PTSD that had his application for firearms licence rejected by the authorities. The second is the case of a labourer who suffers from a depressive disorder, temporarily incapable of work. The third is the case of a war veteran, a chronic alcoholic with toxic epilepsy, who is applying for invalidity retirement but wants to keep his driving license. CONCLUSION: Occupational medicine assess every single worker by applying advanced methods and psycho tests that enable a thorough assessment of work capacity and fitness for carriage of firearms, driving as well as the assessment of psychiatric disorders, which are the most delicate to assess.

scholarly journals What Started Your Labor? Responses From Mothers in the Third Pregnancy, Infection, and Nutrition Study

2014 ◽  
Vol 23 (3) ◽  
pp. 155-164 ◽  
Author(s):  
Marit L. Bovbjerg ◽  
Kelly R. Evenson ◽  
Chyrise Bradley ◽  
John M. Thorp
Keyword(s):  
Physical Activity ◽  
Sexual Activity ◽  
Natural Phenomenon ◽  
The Third ◽  
Maternal Illness ◽  
Nutrition Study ◽  
Potential Risks ◽  
Emotional Trigger ◽  
Using Data ◽  
Specific Trigger

Many behaviors and substances have been purported to induce labor. Using data from the Third Pregnancy, Infection, and Nutrition cohort, we focus on 663 women who experienced spontaneous labor. Of the women who reported a specific labor trigger, 32% reported physical activity (usually walking), 24% a clinician-mediated trigger, 19% a natural phenomenon, 14% some other physical trigger (including sexual activity), 12% reported ingesting something, 12% an emotional trigger, and 7% maternal illness. With the exceptions of walking and sexual intercourse, few women reported any one specific trigger, although various foods/substances were listed in the “ingesting something” category. Discussion of potential risks associated with “old wives’ tale” ways to induce labor may be warranted as women approach term.

Primary Headache Associated with Sexual Activity in Adolescents: Illustrative Cases

2021 ◽  
Author(s):  
Jinal Patel ◽  
David A. Rothner
Keyword(s):  
Sexual Activity ◽  
Primary Headache ◽  
Diagnosis And Treatment ◽  
Psychosexual Development ◽  
Adequate Treatment

AbstractPrimary headache associated with sexual activity (PHASA) is well described in adults, but reports in adolescents are lacking. PHASA is likely underreported in adolescents. A delay in or an absence of timely and adequate treatment has the potential to negatively impact normal adolescent psychosexual development. Physicians should consider this disorder in adolescents presenting with headaches, and understand the characteristics, diagnosis, and treatment. We report two cases of PHASA in adolescents and review the epidemiology, presentation, and management.

Evidence of intergenerational transmission of Diethylstilbestrol (DES) health effects: Hindsight and insight

2021 ◽  
Author(s):  
Linda Titus
Keyword(s):  
Cohort Study ◽  
Intergenerational Transmission ◽  
National Cancer Institute ◽  
Case Reports ◽  
Endocrine Disrupting Chemicals ◽  
Third Generation ◽  
Health It ◽  
The Third ◽  
Endocrine Disrupting ◽  
The Us

Abstract This review summarizes key findings from the US National Cancer Institute (NCI) DES Combined Cohort Study with a focus on the results of the NCI Third Generation Study, a cohort of DES-exposed and unexposed granddaughters. Findings to date from the Third Generation Study are discussed in the context of other research efforts and case reports suggesting an intergenerational heritability of DES-related effects. The DES story serves as a model for the influence of endocrine disrupting chemicals on human health. It also serves as a warning of the special hazards of pregnancy exposures, and more broadly, of the potential for invisible health consequences arising from new or changing exposures.

Retroperitoneal Xanthogranuloma; Priority of Case Reports

PEDIATRICS ◽  
1963 ◽  
Vol 31 (5) ◽  
pp. 883-883
Author(s):  
MELVIN S. KRUGLY
Keyword(s):  
British Journal ◽  
Case Reports ◽  
Retroperitoneal Space ◽  
Male Child ◽  
Age Group ◽  
Pediatric Age ◽  
The Third ◽  
Pediatric Age Group

I received a letter from Dr. Walton M. Edwards, requesting us to acknowledge his report of an xanthogranuloma in the retroperitoneal space as the second case in the pediatric literature. Since our paper, "Retroperitoneal Xanthogranuloma"(Pediatrics, 30:608, 1962) was submitted for publication this paper by Captain Douglas H. Sandberg, M.C., and Colonel Walton M. Edwards, M.C., appeared in the British Journal of Urology, 34:47, 1962, reporting a case of xanthogranuloma of the retroperitoneal space in a 3-year-old male child. Our case is therefore the third to be reported in the pediatric age group and not the second as we reported.

Hemicrania continua

2020 ◽  
pp. 203-207
Author(s):  
Johan Lim ◽  
Joost Haan
Keyword(s):  
Age Of Onset ◽  
Primary Headache ◽  
Hemicrania Continua ◽  
Moderate Intensity ◽  
Trigeminal Autonomic Cephalalgias ◽  
The Third ◽  
The Mean ◽  
Autonomic Reflex ◽  
Patients Experience

Hemicrania continua is an uncommon primary headache characterized by continuous, unilateral cranial pain of moderate intensity, more painful exacerbations with cranial autonomic features, and an absolute response to indomethacin. It is considered one of the trigeminal autonomic cephalalgias. Activation of the trigeminal–autonomic reflex and the contralateral posterior hypothalamic grey is thought to play an important role in its pathophysiology. The mean age of onset is in the third decade and there is a female preponderance of 2:1. Hemicrania continua can be divided into a remitting and an unremitting type; most patients suffer from the unremitting type. Any part of the head or neck can be affected, and pain is mainly described as throbbing. Many patients experience migrainous features during exacerbations. Physical and supplementary investigations are mostly normal. Other trigeminal autonomic cephalalgias and migraine are the main differential diagnostic alternatives for consideration.

scholarly journals Hypersensitivity reactions to folic acid: Three case reports and a review of the literature

2018 ◽  
Vol 32 ◽  
pp. 205873841881770
Author(s):  
Eleonora Nucera ◽  
Arianna Aruanno ◽  
Simona Mezzacappa ◽  
Lucilla Pascolini ◽  
Alessandro Buonomo ◽  
...  
Keyword(s):  
Folic Acid ◽  
Drug Eruption ◽  
Adverse Reactions ◽  
Case Reports ◽  
Hypersensitivity Reactions ◽  
Review Of The Literature ◽  
Fixed Drug Eruption ◽  
The Third ◽  
Fixed Drug ◽  
Uncommon Condition

Adverse reactions to folic acid are an extremely uncommon condition; we present three cases of hypersensitivity to folic acid with different symptomatic manifestations. In the first and second cases, we made the diagnosis of IgE-mediate-type allergy to folic acid, while in the third one, we found a fixed drug eruption to folic acid.

scholarly journals Necrotizing fasciitis: A review of three clinical encounters

2018 ◽  
Vol 5 (1) ◽  
pp. 5
Author(s):  
Jaron Pettis ◽  
Neelam Mulji ◽  
Fernando A. Navarro
Keyword(s):  
Soft Tissue ◽  
Necrotizing Fasciitis ◽  
Case Reports ◽  
Disease Process ◽  
The United States ◽  
Soft Tissue Infections ◽  
Wound Debridement ◽  
The Third ◽  
First Case ◽  
Necrotizing Soft Tissue Infections

Background: Necrotizing fasciitis is a potentially lethal soft tissue infection characterized by rampant necrosis and destruction of subcutaneous tissues. Current estimates of necrotizing soft tissue infections in the United States are 4.3 infections per 100,000 of the population. Although the incidence of necrotizing soft tissue infections has decreased in the last decade, the toxic and lethal nature of the disease process lends utmost importance to accurate diagnosis and immediate management. The purpose of this review article is to report three cases of necrotizing fasciitis and provide literature review in regards to hallmark characteristics, predisposing risk factors and treatment optimization.Case: The first case depicts a newly diagnosed 43-year-old male HIV patient with necrotizing fasciitis infection characterized by Klebsiella, Serratia and anaerobic bacteria cultures. The second case describes the course of a 71-year-old male diagnosed with necrotizing fasciitis in the setting of a complicated anal fistula characterized by B. fragilis, S. anginosus and Prevotella species. The third and final case describes the course of a 44-year-old female diagnosed with necrotizing fasciitis in the setting of Ludwig’s Angina characterized by Klebsiella and Dubliensis species. Treatment was initiated with extensive wound debridement, multiple washouts and broad antibiotic regimens in all three cases. Additional hyperbaric oxygen therapy was administered in the third case.Conclusions: These case reports illustrate the range of severity and settings in which necrotizing fasciitis can occur. Significant morbidity and mortality rates are associated with a delay in treatment initiation. Given this, it is of utmost importance to develop and maintain a high clinical acumen for necrotizing soft tissue infections.

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