Serum vitamin C-periodontal relationship in community-dwelling elderly Japanese

2005 ◽  
Vol 32 (1) ◽  
pp. 93-97 ◽  
Author(s):  
N. Amarasena ◽  
H. Ogawa ◽  
A. Yoshihara ◽  
N. Hanada ◽  
H. Miyazaki
Author(s):  
Simerpreet Kukreja

Introduction: Cigarette smoking induces many chronic illnesses, but in developed countries it is a preventable risk factor. However, by increasing the protective protection mechanism, it may be possible to alleviate the smoke-induced damage. As smoking risk is minimised by vitamin C intake, it is recommended that smokers should take more vitamin C. This inverse correlation between both vitamin C intake and serum levels and smoking was independent of age, sex, body weight, ethnicity, and consumption of alcoholic beverages. The negative association between cigarette smoking and serum vitamin C levels continued, following further adjustment for dietary vitamin C intake. The risk of severe hypovitaminosis C, especially when not accompanied by vitamin supplementation, has been increased in smokers. These data indicate that the inverse relationship between smoking and serum vitamin C levels exists independently of dietary intake, while smoking adversely affects preferences for vitamin C rich foods. Methods: A survey method was performed, with 50 smokers (S) receiving either 500 mg of vitamin C or placebo (P) daily for 4 weeks, and 50 non-smokers receiving vitamin C without supplementation. All finished the hearing. Both groups were equal and C: 14.2 + /- 1.8 pack-years was the amount of cigarettes smoked. Concentrations of plasma vitamin C increased significantly (p < 0.005) only in the vitamin C supplement community.  Results: At SMHRC Hospital Nagpur, we examined the relationship between smoking and vitamin C status, dietary and serum vitamin C levels of 100 participants. Smokers of 20 cigarettes a day had the lowest dietary intake of vitamin C and serum levels, whereas smokers of 1-19 cigarettes a day had lower intake of vitamin C and serum levels (compared to respondents who had never smoked. This inverse correlation between vitamin C and smoking intake and serum levels was independent of age, sex, body weight, race, and consumption of alcoholic beverages. The negative association between cigarette smoking and serum vitamin C levels continued, following further adjustment for dietary vitamin C intake. In smokers, the risk of severe hypo-vitaminosis C, particularly when not accompanied by vitamin supplementation, has increased. Conclusion: These data indicate that the inverse relationship between smoking and serum vitamin C levels exists independently of dietary intake, while smoking adversely affects preferences for vitamin C rich foods. A balanced diet for smokers will obtain a hearty recommendation at this time, but guidelines should remain cautious about high-dose nutrition supplements. Keywords: Chain Smoker, Vitamin C, hypo-vitaminosis C and cigarette.


BMJ Open ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. e017946 ◽  
Author(s):  
Shino Bando ◽  
Yasutake Tomata ◽  
Jun Aida ◽  
Kemmyo Sugiyama ◽  
Yumi Sugawara ◽  
...  

ObjectivesTo assess whether oral self-care (tooth brushing, regular dental visits and use of dentures) affects incident functional disability in elderly individuals with tooth loss.DesignA 5.7-year prospective cohort study.SettingOhsaki City, Japan.Participants12 370 community-dwelling individuals aged 65 years and older.Primary outcome measuresIncident functional disability (new long-term care insurance certification).ResultsThe 5.7-year incidence rate of disability was 18.8%. In comparison with participants who had ≥20 teeth, the HRs (95% CIs) for incident functional disability among participants who had 10–19 and 0–9 teeth were 1.15 (1.01–1.30) and 1.20 (1.07–1.34), respectively (p trend<0.05). However, the corresponding values for those who brushed their teeth ≥2 times per day were not significantly higher in the ‘10–19 teeth’ and ‘0–9 teeth’ groups (HRs (95% CI) 1.05 (0.91–1.21) for participants with 10–19 teeth, and 1.09 (0.96–1.23) for participants with 0–9 teeth), although HRs for those who brushed their teeth <2 times per day were significantly higher (HRs (95% CI) 1.32 (1.12–1.55) for participants with 10–19 teeth, and 1.33 (1.17–1.51) for participants with 0–9 teeth). Such a negating association was not observed for other forms of oral self-care.ConclusionsTooth brushing may partially negate the increased risk of incident functional disability associated with having fewer remaining teeth.


PLoS ONE ◽  
2014 ◽  
Vol 9 (11) ◽  
pp. e111810 ◽  
Author(s):  
Itsushi Hayashida ◽  
Yoshimi Tanimoto ◽  
Yuka Takahashi ◽  
Toshiyuki Kusabiraki ◽  
Junko Tamaki

Author(s):  
Erica Figgins ◽  
Yun-Hee Choi ◽  
Mark Speechley ◽  
Manuel Montero-Odasso

Abstract Background Gait speed is a strong predictor of morbidity and mortality in older adults. Understanding the factors associated with gait speed and the associated adverse outcomes will inform mitigation strategies. We assessed the potentially modifiable and nonmodifiable factors associated with gait speed in a large national cohort of middle and older-aged Canadian adults. Methods We examined cross-sectional baseline data from the Canadian Longitudinal Study on Aging (CLSA) Comprehensive cohort. The study sample included 20 201 community-dwelling adults aged 45–85 years. The associations between sociodemographic and anthropometric factors, chronic conditions, and cognitive, clinical, and lifestyle factors and 4-m usual gait speed (m/s) were estimated using hierarchical multivariable linear regression. Results The coefficient of determination, R  2, of the final regression model was 19.7%, with 12.9% of gait speed variability explained by sociodemographic and anthropometric factors, and nonmodifiable chronic conditions and 6.8% explained by potentially modifiable chronic conditions, cognitive, clinical, and lifestyle factors. Potentially modifiable factors significantly associated with gait speed include cardiovascular conditions (unstandardized regression coefficient, B = −0.018; p &lt; .001), stroke (B = −0.025; p = .003), hypertension (B = −0.007; p = .026), serum Vitamin D (B = 0.004; p &lt; .001), C-reactive protein (B = −0.005; p = .005), depressive symptoms (B = −0.003; p &lt; .001), physical activity (B = 0.0001; p &lt; .001), grip strength (B = 0.003; p &lt; .001), current smoking (B = −0.026; p &lt; .001), severe obesity (B = −0.086; p &lt; .001), and chronic pain (B = −0.008; p = .018). Conclusions The correlates of gait speed in adulthood are multifactorial, with many being potentially modifiable through interventions and education. Our results provide a life-course-perspective framework for future longitudinal assessments risk factors affecting gait speed.


2009 ◽  
Vol 57 (6) ◽  
pp. 1132-1133 ◽  
Author(s):  
Mayumi Hirosaki ◽  
Yasuko Ishimoto ◽  
Yoriko Kasahara ◽  
Yumi Kimura ◽  
Akiko Konno ◽  
...  

2016 ◽  
Vol 4 (2) ◽  
pp. 49-56
Author(s):  
Kiran Buge ◽  
◽  
Pradeep Nahar ◽  
N.V. Aundhakar ◽  
Swati Shah ◽  
...  

2000 ◽  
Vol 70 (2) ◽  
pp. 54-64 ◽  
Author(s):  
Jeanne Chantal Essama-Tjani ◽  
Jean-Claude Guilland ◽  
Françoise Fuchs ◽  
Marie Lombard ◽  
Dominique Richard

Vitamin status was assessed in 26 recently institutionalized elderly subjects by combining dietary and biochemical measurements of thiamin, riboflavin, niacin, beta-carotene, vitamins C, A, D and E at admission (P1), and 1.5 (P2), 3.0 (P3), 4.5 (P4), 6.0 (P5), 12 (P6) months later. At admission, except for vitamin A, mean vitamin intakes were lower than the 1992 French Recommended Dietary Allowance. Thiamin, vitamins C, A and E status seemed nearly satisfactory as less than one-fourth of the population sample had blood values lower than the cut-off point for thiamin (erythrocyte thiamin pyrophosphate < 0.17 mumol/l), vitamin A (serum retinol < 1.05 mumol/l), vitamin C (serum vitamin C < 11.3 mumol/l) and vitamin E (serum alpha-tocopherol < 9.3 mumol/l) or higher than the cut-off point for thiamin (erythrocyte transketolase activity coefficient > 1.19). Almost half of the subjects for riboflavin, and almost all non supplemented subjects for vitamin D were in risk of vitamin deficiency (46% had an erythrocyte glutathione reductase activity coefficient > 1.19 and 72% had a plasma 25(OH)D3 < 25 nmol/l). During the study, vitamins status remained unchanged for riboflavin, niacin, vitamins A, D and E, improved for vitamin C (P = 0.004) or impaired for thiamin (P = 0.008). Thus, institutionalization seemed to have no effect on riboflavin, niacin, vitamins A, D and E status and a slight effect on thiamin and vitamin C status.


2013 ◽  
Vol 03 (04) ◽  
pp. 030-033
Author(s):  
Mithra N. Hegde ◽  
Suchetha Kumari ◽  
Nidarsh D. Hegde ◽  
Shilpa S. Shetty

AbstractThe aim of this study was to estimate the vitamin C levels in saliva and serum of caries free and caries active adults and to correlate the vitamin C level with DMFT index (D=decayed, m=missing, f=filled, t=teeth) index. The present study included eighty healthy adults who were divided into four groups; Control, Group- I, Group II and Group- III with a DMFT index 0, <3, <10 and > 10 respectively. Saliva and serum samples were collected from all the four groups. The vitamin C of saliva and serum was estimated by dinitro phenyl hydrazine (DNPH) method. One-way ANOVA was used to compare the vitamin C levels of saliva and serum. Only differences with 'p'value <0.05 were considered statistically significant. Saliva and serum vitamin C level decreases with increase in caries activity and is statistically significant suggesting the powerful antioxidant property of vitamin C.


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