Is the use of a potassium nitrate dentifrice effective in reducing tooth sensitivity related to in‐office bleaching? A randomized triple‐blind clinical trial

2021 ◽  
Author(s):  
María Gracia Ortega‐Moncayo ◽  
Paulina Aliaga‐Sancho ◽  
Camilo Pulido ◽  
Mario Felipe Gutierrez ◽  
Estuardo Rodriguez‐Salazar ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Potassium Nitrate ◽  
Tooth Sensitivity

scholarly journals Treatment of Dentin Hypersensitivity Using Nano-Hydroxyapatite Pastes: A Randomized Three-Month Clinical Trial

2016 ◽  
Vol 41 (4) ◽  
pp. E93-E101 ◽  
Author(s):  
L Wang ◽  
AC Magalhães ◽  
LF Francisconi-dos-Rios ◽  
MP Calabria ◽  
DFG Araújo ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Home Care ◽  
General Linear Model ◽  
Potassium Nitrate ◽  
Dentin Hypersensitivity ◽  
Analog Scale ◽  
The Third ◽  
Significant Difference ◽  
Final Score ◽  
Nested Analysis

SUMMARY Objectives: This randomized clinical trial tested the three-month desensitizing effect of two protocols using nano-hydroxyapatite formulations compared with Pro-Argin and fluoride varnish. Methods: Twenty-eight subjects with 137 teeth presenting dentin exposure with a minimal hypersensitivity of four on the visual analog scale (VAS) took part of this study. The subjects were randomly assigned to four groups: Desensibilize Nano-P paste (20% hydroxyapatite [HAP], potassium nitrate, and sodium fluoride [NaF]; 9000 ppm fluoride [F]); Desensibilize Nano-P associated with experimental home-care pastes (10% HA, potassium nitrate, and NaF; 900 ppm F); Pro-Relief professional paste (8% arginine with Pro-Argin technology) associated with home-care toothpaste (8% arginine, sodium monofluorophosphate, 1450 ppm F); and Duraphat professional varnish (NaF varnish, 22,600 ppm F). The professional treatments were performed in weekly appointments over three weeks. The home-care products were used continuously for three months. A VAS was used to assess the tooth sensitivity response after standardized evaporative stimulus at baseline and after one month and three months. The baseline score was deducted from the final score, and the means were analyzed using nested analysis of variance, while the comparison between times was performed by a general linear model (p<0.05). Results: At the first month all treatments were effective, but there were no significant differences among them (p=0.94). At the third month, despite the fact that NaF varnish had the lowest effect in reducing hypersensitivity, no significant difference was found among the treatments (p=0.09). Only Pro-Relief increased its effect over time (p=0.049). Conclusions: Nano-hydroxyapatite formulations (with or without home->care product association) were as effective as the other treatments in reducing dentin hypersensitivity over three months.

Pre-operative use of dexamethasone does not reduce incidence or intensity of bleaching-induced tooth sensitivity. A triple-blind, parallel-design, randomized clinical trial

2018 ◽  
Vol 23 (1) ◽  
pp. 435-444 ◽  
Author(s):  
Luiz Augusto da Costa Poubel ◽  
Cresus Vinicius Deppes de Gouvea ◽  
Fernanda Signorelli Calazans ◽  
Etyene Castro Dip ◽  
Wesley Veltri Alves ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Tooth Sensitivity ◽  
Parallel Design

Clinical Effects of Desensitizing Prefilled Disposable Trays in In-office Bleaching: A Randomized Single-blind Clinical Trial

2020 ◽  
Vol 45 (1) ◽  
pp. E1-E10
Author(s):  
LM Martins ◽  
LA Lima e Souza ◽  
E Sutil ◽  
LM da Silva ◽  
JOS Silva ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Color Change ◽  
Absolute Risk ◽  
Potassium Nitrate ◽  
Clinical Effects ◽  
Bleaching Agent ◽  
Chi Square ◽  
Peroxide Bleaching ◽  
The Absolute ◽  
Single Blind

SUMMARY Objectives: This study aimed to evaluate the desensitizing effect of a prefilled disposable tray containing potassium nitrate and fluoride on the self-reported tooth sensitivity (TS) and the bleaching efficacy of 40% hydrogen peroxide bleaching agent used for in-office bleaching in comparison with potassium nitrate and fluoride gel applied in a conventional-delivered tray system in an equivalence clinical trial. Methods and Materials: Seventy-eight patients, with a right maxillary canine darker than A3, were selected for this single-blind (evaluators), randomized clinical trial. Teeth were bleached in two sessions with a one-week interval in between. Before in-office bleaching, the prefilled disposable tray or conventional tray containing potassium nitrate and fluoride was used for 15 minutes. Subsequently, the bleaching agent was applied in two 20-minute applications (per the manufacturer's directions) in each session. The color change was evaluated by subjective (Vita Classical and Vita Bleachedguide) and objective (Easyshade Advance Spectrophotometer) methods at baseline and 30 days after the first bleaching session. TS was recorded for up to 48 hours using a 0-10 visual analog scale. The absolute risk was evaluated by chi-square test, while the intensity of TS was evaluated by McNemar test (α=0.05). Color change in shade guide units and ΔE was analyzed by Student t-test for independent samples (α=0.05). Results: Significant whitening was observed in both groups after 30 days of clinical evaluation. The use of different methods of desensitizer in a tray did not influence the absolute risk and intensity of TS (p>0.05), although a tendency of lower risk of TS with the prefilled disposable tray containing potassium nitrate and fluoride was observed. Conclusion: The use of a prefilled disposable tray containing potassium nitrate and fluoride before the application of the in-office bleaching product did not affect the whitening degree and decreased self-reported TS when compared with a conventional-delivered tray system.

scholarly journals In-Office Tooth Bleaching for Adolescents Using Hydrogen Peroxide-Based Gels: Clinical Trial

2017 ◽  
Vol 28 (6) ◽  
pp. 720-725 ◽  
Author(s):  
Marcela Leticia Leal Gonçalves ◽  
Antonio Carlos da Silva Tavares ◽  
Ana Carolina Costa da Mota ◽  
Luiz Alberto Plácido Penna ◽  
Alessandro Melo Deana ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Hydrogen Peroxide ◽  
Statistical Significance ◽  
Young Patients ◽  
Tooth Bleaching ◽  
Controlled Clinical Trial ◽  
Tooth Sensitivity ◽  
Tooth Color ◽  
Bleaching Procedure ◽  
Shade Guide

Abstract The aim of the present study was to evaluate colorimetric changes and tooth sensitivity in adolescents and young patients submitted to tooth bleaching with 20% and 35% hydrogen peroxide. A randomized, controlled, clinical trial was conducted with 53 patients aged 11 to 24 years who were allocated to groups based on the use of the following commercial products: Whiteness HP - FGM® (35% hydrogen peroxide); Whiteness HP Blue Calcium - FGM® (35% hydrogen peroxide); and Whiteness HP Blue Calcium - FGM® (20% hydrogen peroxide). After the bleaching procedure, the visual analog scale was used to measure tooth sensitivity and the Vita Classical Shade guide was used to determine changes in tooth color. Statistical analysis involved the Friedman, Kruskal-Wallis and Student-Newman-Keuls tests, with p≤0.05 considered indicative of statistical significance. The addition of calcium contributed to a reduction in tooth sensitivity, especially when the lower concentration of hydrogen peroxide (20%) was used. Tooth sensitivity occurred in a transitory way and did not influence the tooth bleaching process. Significant differences in color were found after each of the two bleaching sessions. In-office tooth bleaching was considered an effective method for adolescents and young adults. Further studies in this population are necessary in order to fully evaluate the effects of bleaching in young teeth.

Postoperative tooth sensitivity with a new self-adhesive resin cement—a randomized clinical trial

2012 ◽  
Vol 17 (3) ◽  
pp. 793-798 ◽  
Author(s):  
Markus B. Blatz ◽  
Francis K. Mante ◽  
Najeed Saleh ◽  
Alan M. Atlas ◽  
Sahurabh Mannan ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Resin Cement ◽  
Adhesive Resin ◽  
Tooth Sensitivity ◽  
Adhesive Resin Cement

scholarly journals Coadministration of ibuprofen/caffeine on bleaching-induced tooth sensitivity: A randomized clinical trial

2021 ◽  
Vol 32 (3) ◽  
pp. 105-115
Author(s):  
Karine Letícia da Silva ◽  
Elisama Sutil ◽  
Diego Hortkoff ◽  
Renata Maria Oleniki Terra ◽  
Márcia Rezende ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Repeated Measures ◽  
Rating Scale ◽  
Absolute Risk ◽  
Tooth Sensitivity ◽  
Dental Bleaching ◽  
Significance Level ◽  
Significant Difference ◽  
The Absolute

Abstract This clinical trial evaluated the effect of the coadministration of ibuprofen/caffeine on bleaching-induced tooth sensitivity (TS). A triple-blind, parallel-design, randomized clinical trial was conducted on 84 patients who received ibuprofen/caffeine or placebo capsules. The drugs were administered for 48 hours, starting 1 hour before the in-office bleaching. Two bleaching sessions were performed with 35% hydrogen peroxide gel with 1-week interval. TS was recorded up to 48 hours after dental bleaching with a 0-10 visual analogic scale (VAS) and a 5-point numeric rating scale (NRS). The color was evaluated with VITA Classical and VITA Bleachedguide scales (ΔSGU) and VITA Easyshade spectrophotometer (ΔE*ab and ΔE00). The absolute risk of TS in both groups was evaluated using Fischer's exact test. Comparisons of the TS intensity (NRS and VAS data) were performed by using the Mann-Whitney test and a two-way repeated measures ANOVA, respectively. The color alteration between the groups was compared with the Student's t test. The significance level was 5%. There was no statistically significant difference between the groups for the absolute risk of TS (p = 1.00) or for the intensity of TS (p > 0.05). A bleaching of approximately 7 shade guide units was observed on the Vita Classical and Vita Bleachedguide scales, with no statistical difference between the groups. It was concluded that coadministration of ibuprofen and caffeine did not reduce the absolute risk or intensity of TS and did not interfere with the efficacy of dental bleaching.

scholarly journals Combination of strontium chloride and photobiomodulation in the control of tooth sensitivity post-bleaching: A split-mouth randomized clinical trial

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250501
Author(s):  
Danielle da Silva Pompeu ◽  
Brennda Lucy Freitas de Paula ◽  
Antônia Patricia Oliveira Barros ◽  
Samir Costa Nunes ◽  
Alexandra Melo Pingarilho Carneiro ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Near Infrared ◽  
Laser System ◽  
Tooth Bleaching ◽  
Infrared Light ◽  
Controlled Clinical Trial ◽  
Strontium Chloride ◽  
Tooth Sensitivity ◽  
The Individual

Objective This split-mouth randomized controlled clinical trial assessed the effect of 10% strontium chloride in combination with photobiomodulation (PBM) for the control of tooth sensitivity (TS) post-bleaching. Methods The upper/lower, right and left quadrants of fifty volunteers were randomized and allocated to four groups (n = 25): PLACEBO—placebo gel + simulation of PBM; Placebo + PBM; STRONTIUM—10% strontium chloride + simulation of PBM; and PBM + STRONTIUM—10% strontium chloride + PBM. All groups received tooth bleaching treatment with 35% hydrogen peroxide. For the PBM treatment, the laser tip was positioned in the apical and cervical regions of the teeth bleached in the respective hemi-arch. The laser system was operated in continuous mode, using 1.7 J of energy. A dose of 60 J/cm2 was applied to each point for 16 seconds under 808 nm near-infrared light (100mW of power), with a point area of 0.028 cm2. TS was assessed during a 21-day follow-up, using the modified visual analogue scale. Results In the intragroup assessment, the Friedman test indicated that PBM + STRONTIUM promoted the greatest reduction in TS after the second week of treatment (p ≤ 0.05). The Wilcoxon-Mann-Whitney test indicated that the groups Placebo + PBM, STRONTIUM, and STRONTIUM + PBM did not differ statistically (p ≥ 0.05) in the first and third weeks of treatment The group PLACEBO exhibited the greatest TS in the first three days after each bleaching session. Conclusion The combination of 10% strontium chloride with PBM was effective in reducing post-bleaching TS; however, the combination of 10% strontium chloride with PBM was effective in reducing post-bleaching TS; however, it did not differ from the individual use of Placebo + PBM or STRONTIUM groups assessed after 21 days of follow-up.

scholarly journals A randomized split mouth clinical trial of the application of the desensitizer agents for tooth sensitivity

2021 ◽  
Vol 9 (8) ◽  
pp. 2430
Author(s):  
K. Hanisha Reddy ◽  
Afroz Kalmee Syed ◽  
Dasarathi Alivelu ◽  
Haranath Danda ◽  
Ramya Alla
Keyword(s):  
Clinical Trial ◽  
Clinical Effectiveness ◽  
Dentin Hypersensitivity ◽  
Base Line ◽  
Tooth Sensitivity ◽  
The People ◽  
Desensitizing Agents ◽  
Vas Scores ◽  
Barrier Coat ◽  
Line P

Background: Dentin hypersensitivity (DH) affects 3%-75% of the people and is one of the morbid tooth conditions. Hence in the present study we aim to examine the clinical effectiveness of 3 different desensitizing agents in decreasing pain of DH in time of 1 month.Methods: Fifty subjects with cervical DH in at least one tooth in any three of the 4 quadrants were selected. VAS was used to note the pain. Each quadrant in an individual was randomly assigned. Profluorid varnish, Admira protect, and PRG‑Barrier coat was used. VAS scores for the tactile and air stimuli were noted immediately after application, 1 week, and after 1 month. The data was analyzed keeping p<0.05 as significant.Results: VAS significantly reduced for all three groups from the base line (p<0.001). Admira protect showed significant reduction of hypersensitivity scores at 1 month compared to other groups (p<0.001).Conclusions: Admira protect was better at lowering the pain due to DH than PRG‑barrier coat and Profluorid varnish after 1 month of application.

scholarly journals A clinical trial to evaluate the efficacy of 5% potassium nitrate gel on sensitivity during ultrasonic scaling

2019 ◽  
Vol 6 (1) ◽  
pp. 9
Author(s):  
NilofarB Attar ◽  
RajeshP Gaikwad ◽  
AkshayaB Banodkar ◽  
GulnarD Sethna
Keyword(s):  
Clinical Trial ◽  
Potassium Nitrate
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