Food frequency questionnaire as an indicator of the serum composition of essential n -3 and n -6 polyunsaturated fatty acids in early pregnancy, according to body mass index

2014 ◽  
Vol 28 (1) ◽  
pp. 85-94 ◽  
Author(s):  
J. Lepsch ◽  
J. S. Vaz ◽  
J. D. Moreira ◽  
T. J. P. Pinto ◽  
M. Soares-Mota ◽  
...  
2018 ◽  
Vol 88 (5-6) ◽  
pp. 263-269 ◽  
Author(s):  
Fariba Koohdani ◽  
Gity Sotoudeh ◽  
Zahra Kalantar ◽  
Anahita Mansoori

Abstract. Background: Peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala polymorphism (rs1801282) has been associated with metabolic syndrome components in some studies. Moreover, the PPARγ gene may mediate the physiological response to dietary fat intake in a ligand-dependent manner. Methods: Metabolic syndrome components (body mass index, waist circumference, and lipid profile) were determined in 290 type 2 diabetes mellitus patients in a cross-sectional study. DNA genotyping for determining PPARγ Pro12Ala polymorphism was conducted using the polymerase chain reaction-restriction length polymorphism method. A semi-quantitative food frequency questionnaire was used to assess the participants’ dietary intakes in the previous year. Results: There were significant differences between the two genotype groups of PPARγ Pro12Ala polymorphism, Ala carriers (Pro/Ala + Ala/Ala) versus non-Ala carriers (Pro/Pro), in terms of mean body mass index (p = 0.04) and waist circumference (p = 0.02). Below the median percentage of energy from monounsaturated and polyunsaturated fatty acids, Ala carriers had a higher body mass index (p = 0.01) compared to non-Ala carriers. Furthermore, a significant interaction between this single-nucleotide polymorphism and polyunsaturated fatty acids intake on serum triglyceride levels (p = 0.01) was seen, and in higher polyunsaturated fatty acids intake (≥ median) Ala carriers had lower triglyceride levels than non-Ala carriers (p = 0.007). Conclusions: The findings of the current study support a significant association between PPARγ Pro12Ala polymorphism and metabolic syndrome components, and they suggest that this polymorphism can modulate the biological response of dietary fat intake on body mass index and triglyceride levels.


2006 ◽  
Vol 59 (9) ◽  
pp. 994-1001 ◽  
Author(s):  
Laura Paalanen ◽  
Satu Männistö ◽  
Mikko J. Virtanen ◽  
Paul Knekt ◽  
Leena Räsänen ◽  
...  

Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1863 ◽  
Author(s):  
Isabelle Herter-Aeberli ◽  
Celeste Graf ◽  
Anna Vollenweider ◽  
Isabelle Häberling ◽  
Pakeerathan Srikanthan ◽  
...  

Population-based data suggest that high intake of omega-3 (n-3) polyunsaturated fatty acids (PUFA) may be beneficial in a variety of health conditions. It is likely that mainly those patients with preexisting n-3 deficiency are those that benefit most from n-3 fatty acid supplementation. Therefore, for targeted interventions, a fast and reliable screening tool for n-3 PUFA intake is necessary. Thus, the aim of this project was to adapt and validate a food frequency questionnaire (FFQ) for n-3 PUFA intake in Switzerland while using as references the following: (1) 7-day food records (FR), and (2) n-3 fatty acid composition of red blood cells (RBC). We recruited 46 healthy adults for the first part of the study and 152 for the second. We used the dietary software EBISpro for the analysis of n-3 PUFA intake. RBC fatty acid composition was determined by gas chromatography mass spectrometry (GC-MS). Using correlation analysis, we found a moderate significant association between FFQ and FR for α-linolenic acid (ALA), eicosapentanoic acid (EPA), docosahexanoic acid (DHA), and total n-3 fatty acids (all r between 0.523 and 0.586, all p < 0.001). Bland Altman analysis further showed good agreement between the two methods and no proportional bias. Correlations between FFQ and RBC fatty acid composition were also moderate for EPA and DHA (r = 0.430 and r = 0.605, p < 0.001), but weaker for ALA and total n-3 (r = 0.314 and r = 0.211, p < 0.01). The efficacy of the FFQ to classify individuals into the same or adjacent quartile of RBC PUFA content ranged between 70% and 87% for the different fatty acids. In conclusion, we showed that the Swiss n-3 PUFA FFQ is a valid tool to assess dietary n-3 PUFA intake, especially DHA and EPA, to determine population groups at risk for low intake.


2020 ◽  
Vol 4 (1) ◽  
pp. 43
Author(s):  
Dida Akhmad Gurnida ◽  
Nanan Nur'aeny ◽  
Dzulfikar Djalil Lukmanul Hakim ◽  
Fransisca Sri Susilaningsih ◽  
Dewi Marhaeni Diah Herawati ◽  
...  

Pendahuluan:  Usia anak merupakan masa yang penting dalam kehidupan manusia dengan ditandai oleh proses tumbuh kembang. Pertumbuhan dan perkembangan anak perlu didukung oleh asupan makanan yang seimbang. Salah satu parameter peisnilaian status gizi adalah indeks massa tubuh (IMT). Tujuan penelitian ini adalah untuk menganalis korelasi antara tingkat asupan dan kecukupan gizi dengan IMT. Metoda: Jenis penelitian analitik observasional dengan desain korelasional dilaksanakan di SDN 1 Tempuran Karawang pada Bulan Oktober 2018. Subjek penelitian adalah siswa kelas 4, 5 dan 6 sebanyak 62 anak yang dilakukan secara konsekutif. Pengumpulan data melalui pengukuran berat badan, tinggi badan dan pengisian form food frequency questionnaire (FFQ). Analisis data dengan uji korelasi pearson product moment Hasil: Kebanyakan subjek adalah siswa perempuan (55%), berusia 11 tahun (45%), IMT normal (47%), tingkat kecukupan energi dan zat gizi defisit tingkat berat (65%). Uji korelasi antara tingkat kecukupan energi, protein, karbohidrat dan lemak dengan IMT menunjukkan korelasi lemah dalam arah negatif dan tidak signifikan yaitu -0,200 (p= 0,120), -0,188 (p=0,143), -0,162 (p=0,209), dan -0,179 (p=0,163) secara berurutan. Simpulan: Tingkat kecukupan gizi yang terdiri dari energi, protein, karbohidrat dan lemak dengan IMT menunjukkan korelasi lemah dalam arah negatif pada siswa kelas 4,5 dan 6.Kata kunci: Indeks massa tubuh, korelasi, siswa sekolah dasar, tingkat kecukupan gizi. ABSTRACTIntroduction: Childhood age is an important period in human life marked by the process of growth and development. Growth and development of children need to be supported by balanced food intake. One parameter for assessing nutritional status is the body mass index (BMI). The purpose of this study was to analyse the correlation between the level of intake and nutritional adequacy with BMI. Method: This study was an observational analytic study with a correlational design carried out at Tempuran 1 Public Elementary School Karawang in October 2018. The research sample consisted of 62 students from grade 4, 5, and 6, taken by consecutive sampling. Data collected through measurements of body weight, height, and filling out the food frequency questionnaire (FFQ) form. Data analysis was performed with the Pearson product-moment correlation test. Results: Female students (55%), aged 11 (45%), normal BMI (47%), the level of energy and nutrient adequacy showed a severe deficit level (65%) and the correlation test between the level of adequacy energy, protein, carbohydrate and fat with BMI showed a weak correlation in a negative direction and not significant, namely -0.200 (p = 0.120); -0.188 (p = 0.143); -0.162 (p = 0.209), and -0.179 (p = 0.163) ) sequentially. Conclusion: The level of nutritional adequacy of grades 4, 5, and 6 elementary students consisting of energy, protein, carbohydrates, and fats shows a weak correlation in a negative direction with BMI.Keywords: Nutrition adequacy level, body mass index, students, elementary school.


2019 ◽  
Vol 75 (1) ◽  
pp. 77-85
Author(s):  
Kerry S. Flannagan ◽  
Sheila Gahagan ◽  
Arun K. Das ◽  
Raquel A. Burrows ◽  
Betsy Lozoff ◽  
...  

Background: Polyunsaturated fatty acids (PUFA) status in childhood may be associated with adiposity development. Objective: To assess associations of serum PUFA biomarkers in childhood with change in body mass index (BMI)-for-age Z scores (BMIZ) through adolescence. Methods: We quantified serum PUFA at ages 5 and 10 years among 418 children from Santiago, Chile. BMI was measured at 5, 10, and 16 years. We compared BMIZ change through age 16 years between quartiles of PUFA at 5 and 10 years and PUFA change 5–10 years by fitting growth curves from mixed effects models. Results: At age 5 years, serum docosahexaenoic acid was inversely associated with BMIZ change from ages 5 to 16 years. At age 10 years, arachidonic acid (AA) was nonlinearly positively related to BMIZ change from ages 10 to 16 years. Change in AA and the Δ5-desaturase (D5D) activity index between 5 and 10 years were each positively associated with BMIZ change from ages 10 to 16 years. Change in eicosapentaenoic acid was inversely associated with change in BMIZ. Conclusions: Serum long-chain n-3 PUFA in middle childhood were associated with less BMI gain through adolescence, whereas AA and D5D activity was related to greater BMI gain.


2020 ◽  
Vol 4 (3) ◽  
pp. 144-149
Author(s):  
Giulia D’Alberti ◽  
Carla Ferreri ◽  
Anna Vita Larocca ◽  
Pierangelo Torquato ◽  
Antonio Boccuto ◽  
...  

AbstractLipid disorders have been implicated in overweight and menopause. However, evidence on lipidomic analysis of fatty acids in erythrocytes of menopausal women is scarce. The aim of this study was to investigate the relationship between the body mass index within or beyond 5 years of menopause and erythrocyte fatty acid profile. This case-control study was conducted on out of 37 menopausal women total patients, 22 with body mass index ≥ 25 and 12 matched controls (body mass index <25). Experimental procedures were performed on the blood through robotic equipment for isolation of erythrocyte and cell membrane fatty acids were analyzed by using gas-liquid chromatography. Results showed that erythrocyte membranes did not change significantly in lipid composition between case and control group. However, the percentage of women who had a physiological content of saturated fatty acids was lower in case than in control group, and the percentage of women who had a physiological content of monounsaturated fatty acids and polyunsaturated fatty acids was lower in control than in case group. Woman with BMI>25 and non-physiological content of fatty acids, were richer in percentage of saturated fatty acids and poorer of monounsaturated fatty acids and polyunsaturated fatty acids than women with BMI<25. The percentage of physiological n-6/n-3 polyunsaturated ratio was lower in women with BMI>25 than in women with BMI<25. Interestingly, the percentage of patients that had physiological values of lipids beyond 5 years of menopause increased in comparison patients within 5 years of menopause. Notably, n-6/n-3 polyunsaturated fatty acids physiological ratio beyond 5 years of menopause increased in both case and control patients, indicating normalization over time. In conclusion erythrocytes fatty acids composition may be related to the body mass index and to the time from menopause.


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