scholarly journals CONCENTRATIONS OF POLYUNSATURATED FATTY ACIDS BY BODY MASS INDEX AMONG ARCTIC RESIDENTS

Human Ecology ◽  
2020 ◽  
pp. 4-10
Author(s):  
D. S. Galstyan ◽  
F. A. Bichkaeva ◽  
N. F. Baranova
Keyword(s):  
Body Mass Index ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Body Mass

PPARγ Pro12Ala Polymorphism Influences the Relationship between Dietary Fat Intake, Adiposity and Lipid Profile in Patients with Type 2 Diabetes

2018 ◽  
Vol 88 (5-6) ◽  
pp. 263-269 ◽  
Author(s):  
Fariba Koohdani ◽  
Gity Sotoudeh ◽  
Zahra Kalantar ◽  
Anahita Mansoori
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Body Mass ◽  
Dietary Fat ◽  
Fat Intake ◽  
Pro12ala Polymorphism ◽  
Dietary Fat Intake ◽  
Metabolic Syndrome Components

Abstract. Background: Peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala polymorphism (rs1801282) has been associated with metabolic syndrome components in some studies. Moreover, the PPARγ gene may mediate the physiological response to dietary fat intake in a ligand-dependent manner. Methods: Metabolic syndrome components (body mass index, waist circumference, and lipid profile) were determined in 290 type 2 diabetes mellitus patients in a cross-sectional study. DNA genotyping for determining PPARγ Pro12Ala polymorphism was conducted using the polymerase chain reaction-restriction length polymorphism method. A semi-quantitative food frequency questionnaire was used to assess the participants’ dietary intakes in the previous year. Results: There were significant differences between the two genotype groups of PPARγ Pro12Ala polymorphism, Ala carriers (Pro/Ala + Ala/Ala) versus non-Ala carriers (Pro/Pro), in terms of mean body mass index (p = 0.04) and waist circumference (p = 0.02). Below the median percentage of energy from monounsaturated and polyunsaturated fatty acids, Ala carriers had a higher body mass index (p = 0.01) compared to non-Ala carriers. Furthermore, a significant interaction between this single-nucleotide polymorphism and polyunsaturated fatty acids intake on serum triglyceride levels (p = 0.01) was seen, and in higher polyunsaturated fatty acids intake (≥ median) Ala carriers had lower triglyceride levels than non-Ala carriers (p = 0.007). Conclusions: The findings of the current study support a significant association between PPARγ Pro12Ala polymorphism and metabolic syndrome components, and they suggest that this polymorphism can modulate the biological response of dietary fat intake on body mass index and triglyceride levels.

scholarly journals Serum Polyunsaturated Fatty Acids in Middle Childhood and Body Mass Index Change Through Adolescence

2019 ◽  
Vol 75 (1) ◽  
pp. 77-85
Author(s):  
Kerry S. Flannagan ◽  
Sheila Gahagan ◽  
Arun K. Das ◽  
Raquel A. Burrows ◽  
Betsy Lozoff ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Body Mass ◽  
Middle Childhood ◽  
Activity Index ◽  
Growth Curves ◽  
Δ5 Desaturase ◽  
Z Scores ◽  
Development Objective

Background: Polyunsaturated fatty acids (PUFA) status in childhood may be associated with adiposity development. Objective: To assess associations of serum PUFA biomarkers in childhood with change in body mass index (BMI)-for-age Z scores (BMIZ) through adolescence. Methods: We quantified serum PUFA at ages 5 and 10 years among 418 children from Santiago, Chile. BMI was measured at 5, 10, and 16 years. We compared BMIZ change through age 16 years between quartiles of PUFA at 5 and 10 years and PUFA change 5–10 years by fitting growth curves from mixed effects models. Results: At age 5 years, serum docosahexaenoic acid was inversely associated with BMIZ change from ages 5 to 16 years. At age 10 years, arachidonic acid (AA) was nonlinearly positively related to BMIZ change from ages 10 to 16 years. Change in AA and the Δ5-desaturase (D5D) activity index between 5 and 10 years were each positively associated with BMIZ change from ages 10 to 16 years. Change in eicosapentaenoic acid was inversely associated with change in BMIZ. Conclusions: Serum long-chain n-3 PUFA in middle childhood were associated with less BMI gain through adolescence, whereas AA and D5D activity was related to greater BMI gain.

Overweight and erythrocyte polyunsaturated fatty acid changes in menopause

2020 ◽  
Vol 4 (3) ◽  
pp. 144-149
Author(s):  
Giulia D’Alberti ◽  
Carla Ferreri ◽  
Anna Vita Larocca ◽  
Pierangelo Torquato ◽  
Antonio Boccuto ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Body Mass ◽  
Saturated Fatty Acids ◽  
Monounsaturated Fatty Acids ◽  
The Body ◽  
Control Group ◽  
Menopausal Women ◽  
And Control

AbstractLipid disorders have been implicated in overweight and menopause. However, evidence on lipidomic analysis of fatty acids in erythrocytes of menopausal women is scarce. The aim of this study was to investigate the relationship between the body mass index within or beyond 5 years of menopause and erythrocyte fatty acid profile. This case-control study was conducted on out of 37 menopausal women total patients, 22 with body mass index ≥ 25 and 12 matched controls (body mass index <25). Experimental procedures were performed on the blood through robotic equipment for isolation of erythrocyte and cell membrane fatty acids were analyzed by using gas-liquid chromatography. Results showed that erythrocyte membranes did not change significantly in lipid composition between case and control group. However, the percentage of women who had a physiological content of saturated fatty acids was lower in case than in control group, and the percentage of women who had a physiological content of monounsaturated fatty acids and polyunsaturated fatty acids was lower in control than in case group. Woman with BMI>25 and non-physiological content of fatty acids, were richer in percentage of saturated fatty acids and poorer of monounsaturated fatty acids and polyunsaturated fatty acids than women with BMI<25. The percentage of physiological n-6/n-3 polyunsaturated ratio was lower in women with BMI>25 than in women with BMI<25. Interestingly, the percentage of patients that had physiological values of lipids beyond 5 years of menopause increased in comparison patients within 5 years of menopause. Notably, n-6/n-3 polyunsaturated fatty acids physiological ratio beyond 5 years of menopause increased in both case and control patients, indicating normalization over time. In conclusion erythrocytes fatty acids composition may be related to the body mass index and to the time from menopause.

scholarly journals Nutritional assessment of Esmeraldan adult population (Ecuador)

2017 ◽  
Vol 30 (6) ◽  
pp. 735-746 ◽  
Author(s):  
Sonia MATEOS-MARCOS ◽  
María Pilar VILLENA-ESPONERA ◽  
Rafael MORENO-ROJAS
Keyword(s):  
Body Mass Index ◽  
Fatty Acids ◽  
Vitamin E ◽  
Waist Circumference ◽  
Body Mass ◽  
Nutrient Intake ◽  
Nutritional Assessment ◽  
Adult Population ◽  
Nutrient Intakes ◽  
Dietary Reference Intakes

ABSTRACT Objective To analyse the nutritional status of the adult population in Esmeraldas by means of anthropometric measurements, the input of macro and micronutrients in the diet, and the adequacy estimation of nutrient intake by hispanic Dietary Reference Instakes along with the sex and the age influence. Methods Nutrient intake data were obtained by personal interview with the application of two 24 hour recalls (weekend and weekday). The anthropometric indicators analysed were body mass index, waist circumference and blood pressure. Nutriplato version 2.0 software was used for the two 24-hours food recall surveys data processing, and for the respective calculations of macronutrients, micronutrients and Dietary Reference Intakes. Means and standard deviations were calculated for anthropometry, nutrient intakes and Dietary Reference Instakes. The General Linear Model was applied to identify differences in relation to nutrient intakes considering sex, profession, body mass index, group, origin and day of the week as factors. Results Statistical analysis showed significant differences mainly in carbohydrates, fiber, calcium, phosphorus, iron, sodium, iodine, and vitamin E. Dietary intakes were compared with the Federación Española de Sociedades de Nutrición, Alimentación y Dietética Dietary Reference Intakes requirements and calcium, potassium, iodine, riboflavin, pantothenic acid, biotin, vitamin D, vitamin E, fiber, monounsaturated fatty acids and polyunsaturated fatty acids are below the Dietary Reference Instakes in all ages and gender subgroups. The anthropometric results obtained indicated that 67.0% of the population were overweight and obese, the 87.7% of the adults suffered from prehypertension and the waist circumference indicated that 73.0% of the subjects were established in the range of high risk of cardiovascular disease. Conclusion Priority nutrition actions and interventions are needed to be developed in Esmeraldas adult population.

scholarly journals Nutrient Intake of Crohn’s Patients: Is There Consistency be-tween Crohn’s Disease Activity Index, Subjective Global As-sessment and Body Mass Index?

2021 ◽  
Author(s):  
Neriman İnanç ◽  
Yağmur Yaşar Fırat ◽  
Eda Başmısırlı ◽  
Aslı Gizem Çapar
Keyword(s):  
Body Mass Index ◽  
Fatty Acids ◽  
Vitamin E ◽  
Disease Activity ◽  
Body Mass ◽  
Nutrient Intake ◽  
Unsaturated Fatty Acids ◽  
Activity Index ◽  
Disease Activity Index ◽  
Daily Energy

Background: We aimed to determine the nutrient intake of Crohn’s patients and to expose its relationship with Crohn’s Activity Index (CDAI), Subjective Global Assessment (SGA) and Body Mass Index (BMI). Methods: This randomized controlled trial was conducted on patients enrolled in the Gastroenterology Polyclinic of a University Medical Faculty Hospital, Kayseri, Turkey in 2017. Two groups were included in this study: Crohn’s Group (n = 100) and Control (n = 89). Crohn’s Disease Activity Index was used to detect disease activity. Malnutrition risk was determined by the SGA and daily energy and nutrient intakes were calculated. Results: There was a significant relationship between SGA and both CDAI and BMI (P<0.001, P=0.008, respectively). Daily energy, carbohydrate, monosaccharide, starch, sucrose, fructose, poly-unsaturated fatty acids, omega-3 fatty acids, fiber, vitamin E and C, thiamine, niacin, pyridoxine, Mg, P, Fe, Cu, Zn intakes were significantly lower in Crohn’s Group than in Control Group. While more than 50% of the patients did not consume enough, B6, C, thiamine, niacin, folic acid, Mg, Ca and fiber, intakes of vitamin E, riboflavin, Fe, P, and Zn were adequate. Energy and nutrient  (vitamin E, thiamine, vitamin B6, mono and poly unsaturated fatty acids, saturated fatty acids, Mg, Ca, P, Zn, n-3 fatty acids and starch) intakes were negatively correlated with CDAI, but there was no relationship between these intakes and SGA. Conclusion: There was a relationship between CDAI, SGD and BMI used to determine nutritional status in patients with Crohn’s.

scholarly journals SUN-585 Associations Between UCP1(rs1800592),UCP2(rs6593366) and UCP3(rs1800849) with Fasting Glucose, Body Mass Index, and Energy Expenditure

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Nicté Figueroa-Vega ◽  
Elva L Perez-Luque ◽  
Juan M Malacara
Keyword(s):  
Body Mass Index ◽  
Fatty Acids ◽  
Energy Expenditure ◽  
Body Mass ◽  
Energy Homeostasis ◽  
Fasting Glucose ◽  
Resting Energy Expenditure ◽  
Allelic Discrimination ◽  
Brown Adipose ◽  
Obese Subjects

Abstract Background: The uncoupling proteins (UCPs) belong to the mitochondrial inner membrane anion carrier superfamily and play an important role in energy homeostasis. UCP-1 is expressed mostly in brown adipose tissue (BAT) and act in the thermogenesis and regulation of energy expenditure. UCP-2 has a role in the metabolism of fatty acids direct and indirectly path insulin secretion. UCP-3 is specific of skeletal muscle and BAT and may affects the adaptive and translocation of fatty acids. Genetic polymorphisms in these proteins have been associated with obesity, as rs1800592 (-3826 A/G) in UCP-1 gene. The rs659366 (-866GA) UCP-2 has being associated with high expression of its RNAm, decrease of obesity risk, and increase of energy expenditure. The rs1800849 (-55CT) UCP-3 has been associated with low risk of type 2 Diabetes Mellitus, but its association with body mass index is controversial. Objective: To analyze the association of the polymorphisms rs1800592 UCP-1, rs659366 UCP-2, and rs1800849 UCP-3 with BMI and resting energy expenditure (REE). Material and Methods: We included 120 subjects with BMI&gt;30kg/m2 and 100 subjects with BMI between18.5 -24.9 kg/m2, aged 20 to 50 years. Anthropometric data were recorded and the REE was measure for indirect calorimetric. Fasting glucose and lipid profile were assessed. Leptin, insulin and acylated-ghrelin were quantified by ELISA. Genomic DNA was extracted using comercial kit. Genotyping for three polymorphisms was performed by allelic discrimination using Taqman probes. Results: All the three polymorphisms of UCPs showed distribution in accordance with Hardy-Weinberg equilibrium. The weight, BMI, glucose, triglycerides, leptin, insulin, HOMA-IR, and REE levels were signitifcantly higher in obese subjects. There was a strong correlation between REE with BMI (r=0.42, p&lt;0.00001) and with insulin levels (r=0.229, p=0.001) in all group. No differences in genotypic and allelic frequencies of rs1800592 UCP-1, rs659366 UCP-2 and rs180084 UCP-3 polymorphisms between obese and lean subjects. No differences among the genotypes rs1800592 UCP-1 and rs1800849 UCP-3 with metabolic variables. In rs659366 UCP-2 polymorhism, the REE and glucose concentrations were lower in carriers of rs659366AA genotype (F=3.11, p=0.046; F=2.97, p=0.053, respectively) in whole group. In obese subjects with rs659366AA UCP-2 genotype, the REE was significantly low (F=4.15, P=0.017). Conclusion. In this work the obese subjects with rs659366AA genotype had low REE. We found low glucose concentrations in the carries of rs659366 AA genotype.

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