Directional, Regional, and Layer Variations of Mechanical Properties of Esophageal Tissue and its Interpretation Using a Structure-Based Constitutive Model

2005 ◽  
Vol 128 (3) ◽  
pp. 409-418 ◽  
Author(s):  
W. Yang ◽  
T. C. Fung ◽  
K. S. Chian ◽  
C. K. Chong

The esophagus, like other soft tissues, exhibits nonlinear and anisotropic mechanical properties. As a composite structure, the properties of the outer muscle and inner mucosal layer are different. It is expected that the complex mechanical properties will induce nonhomogeneous stress distributions in the wall and nonuniform tissue remodeling. Both are important factors which influence the function of mechanosensitive receptor located in various layers of the wall. Hence, the characterization of the mechanical properties is essential to understand the neuromuscular motion of the esophagus. In this study, the uniaxial tensile tests were conducted along two mutually orthogonal directions of porcine esophageal tissue to identify the directional (circumferential and axial), regional (abdominal, thoracic, and cervical), and layer (muscle and mucosa) variations of the mechanical properties. A structure-based constitutive model, which took the architectures of the tissue’s microstructures into account, was applied to describe the mechanical behavior of the esophagus. Results showed that the constitutive model successfully described the mechanical behavior and provided robust estimates of the material parameters. In conclusion, the model was demonstrated to be a good descriptor of the mechanical properties of the esophagus and it was able to facilitate the directional, layer, and regional comparisons of the mechanical properties in terms of the associated material parameters.

2019 ◽  
Vol 9 (14) ◽  
pp. 2851 ◽  
Author(s):  
Up Huh ◽  
Chung-Won Lee ◽  
Ji-Hun You ◽  
Chan-Hee Song ◽  
Chi-Seung Lee ◽  
...  

In this study, computational simulations and experiments were performed to investigate the mechanical behavior of the aorta wall because of the increasing occurrences of aorta-related diseases. The study focused on the deformation and strength of porcine and healthy human abdominal aortic tissues under uniaxial tensile loading. The experiments for the mechanical behavior of the arterial tissue were conducted using a uniaxial tensile test apparatus to validate the simulation results. In addition, the strength and stretching of the tissues in the abdominal aorta of a healthy human as a function of age were investigated based on the uniaxial tensile tests. Moreover, computational simulations using the ABAQUS finite element analysis program were conducted on the experimental scenarios based on age, and the Holzapfel–Gasser–Ogden (HGO) model was applied during the simulation. The material parameters and formulae to be used in the HGO model were proposed to identify the failure stress and stretch correlation with age.


Author(s):  
M. A. J. Cox ◽  
R. A. Boerboom ◽  
C. V. C. Bouten ◽  
N. J. B. Driessen ◽  
F. P. T. Baaijens

Over the last few years, research interest in tissue engineering as an alternative for e.g. current treatment and replacement strategies for cardiovascular and heart valve diseaes has significantly increased. In vitro mechanical conditioning is an essential tool for engineering strong implantable tissues [1]. Detailed knowledge of the mechanical properties of the native tissue as well as the properties of the developing engineered constructs is vital for a better understanding and control of the mechanical conditioning process. The typical highly nonlinear and anisotropic behavior of soft tissues puts high demands on their mechanical characterization. Current standards in mechanical testing of soft tissues include (multiaxial) tensile testing and indentation tests. Uniaxial tensile tests do not provide sufficient information for characterizing the full anisotropic material behavior, while biaxial tensile tests are difficult to perform, and boundary effects limit the test region to a small central portion of the tissue. In addition, characterization of the local tissue properties from a tensile test is non-trivial. Indentation tests may be used to overcome some of these limitations. Indentation tests are easy to perform and when indenter size is small relative to the tissue dimensions, local characterization is possible. Therefore, we propose a spherical indentation test using finite deformations.


Author(s):  
M. Carraturo ◽  
G. Alaimo ◽  
S. Marconi ◽  
E. Negrello ◽  
E. Sgambitterra ◽  
...  

AbstractAdditive manufacturing (AM), and in particular selective laser melting (SLM) technology, allows to produce structural components made of lattice structures. These kinds of structures have received a lot of research attention over recent years due to their capacity to generate easy-to-manufacture and lightweight components with enhanced mechanical properties. Despite a large amount of work available in the literature, the prediction of the mechanical behavior of lattice structures is still an open issue for researchers. Numerical simulations can help to better understand the mechanical behavior of such a kind of structure without undergoing long and expensive experimental campaigns. In this work, we compare numerical and experimental results of a uniaxial tensile test for stainless steel 316L octet-truss lattice specimen. Numerical simulations are based on both the nominal as-designed geometry and the as-build geometry obtained through the analysis of µ-CT images. We find that the use of the as-build geometry is fundamental for an accurate prediction of the mechanical behavior of lattice structures.


Author(s):  
Fulufhelo Nemavhola

AbstractRegional mechanics of the heart is vital in the development of accurate computational models for the pursuit of relevant therapies. Challenges related to heart dysfunctioning are the most important sources of mortality in the world. For example, myocardial infarction (MI) is the foremost killer in sub-Saharan African countries. Mechanical characterisation plays an important role in achieving accurate material behaviour. Material behaviour and constitutive modelling are essential for accurate development of computational models. The biaxial test data was utilised to generated Fung constitutive model material parameters of specific region of the pig myocardium. Also, Choi-Vito constitutive model material parameters were also determined in various myocardia regions. In most cases previously, the mechanical properties of the heart myocardium were assumed to be homogeneous. Most of the computational models developed have assumed that the all three heart regions exhibit similar mechanical properties. Hence, the main objective of this paper is to determine the mechanical material properties of healthy porcine myocardium in three regions, namely left ventricle (LV), mid-wall/interventricular septum (MDW) and right ventricle (RV). The biomechanical properties of the pig heart RV, LV and MDW were characterised using biaxial testing. The biaxial tests show the pig heart myocardium behaves non-linearly, heterogeneously and anisotropically. In this study, it was shown that RV, LV and MDW may exhibit slightly different mechanical properties. Material parameters of two selected constitutive models here may be helpful in regional tissue mechanics, especially for the understanding of various heart diseases and development of new therapies.


2021 ◽  
pp. 073168442110204
Author(s):  
Bin Yang ◽  
Yingying Shang ◽  
Zeliang Yu ◽  
Minger Wu ◽  
Youji Tao ◽  
...  

In recent years, coated fabrics have become the major material used in membrane structures. Due to the special structure of base layer and mechanical properties, coated biaxial warp-knitted fabrics are increasingly applied in pneumatic structures. In this article, the mechanical properties of coated biaxial warp-knitted fabrics are investigated comprehensively. First, off-axial tensile tests are carried out in seven in-plane directions: 0°, 15°, 30°, 45°, 60°, 75°, and 90°. Based on the stress–strain relationship, tensile strengths are obtained and failure modes are studied. The adaptability of Tsai–Hill criterion is analyzed. Then, the uniaxial tensile creep test is performed under 24-h sustained load and the creep elongation is calculated. Besides, tearing strengths in warp and weft directions are obtained by tearing tests. Finally, the biaxial tensile tests under five different load ratios of 1:1, 2:1, 1:2, 1:0, and 0:1 are carried out, and the elastic constants and Poisson’s ratio are calculated using the least squares method based on linear orthotropic assumption. Moreover, biaxial specimens under four load ratios of 3:1, 1:3, 5:1, and 1:5 are further tensile tested to verify the adaptability of linear orthotropic model. These experimental data offer a deeper and comprehensive understanding of mechanical properties of coated biaxial warp-knitted fabrics and could be conveniently adopted in structural design.


Materials ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 252
Author(s):  
Rongchuang Chen ◽  
Shiyang Zhang ◽  
Xianlong Liu ◽  
Fei Feng

To investigate the effect of hot working parameters on the flow behavior of 300M steel under tension, hot uniaxial tensile tests were implemented under different temperatures (950 °C, 1000 °C, 1050 °C, 1100 °C, 1150 °C) and strain rates (0.01 s−1, 0.1 s−1, 1 s−1, 10 s−1). Compared with uniaxial compression, the tensile flow stress was 29.1% higher because dynamic recrystallization softening was less sufficient in the tensile stress state. The ultimate elongation of 300M steel increased with the decrease of temperature and the increase of strain rate. To eliminate the influence of sample necking on stress-strain relationship, both the stress and the strain were calibrated using the cross-sectional area of the neck zone. A constitutive model for tensile deformation was established based on the modified Arrhenius model, in which the model parameters (n, α, Q, ln(A)) were described as a function of strain. The average deviation was 6.81 MPa (6.23%), showing good accuracy of the constitutive model.


2015 ◽  
Vol 732 ◽  
pp. 161-164 ◽  
Author(s):  
Jan Vesely ◽  
Lukas Horny ◽  
Hynek Chlup ◽  
Milos Beran ◽  
Milan Krajicek ◽  
...  

The effects of the polyvinyl alcohol (PVA) concentration on mechanical properties of hydrogels based on blends of native or denatured collagen / PVA were examined. Blends of PVA with collagen were obtained by mixing the solutions in different ratios, using glycerol as a plasticizer. The solutions were cast on polystyrene plates and the solvent was allowed to evaporate at room temperature. Uniaxial tensile tests were performed in order to obtain the initial modulus of elasticity (up to deformation 0.1), the ultimate tensile stress and the deformation at failure of the material in the water-saturated hydrogel form. It was found that the material was elastic and the addition of PVA helped to enhance both the ultimate tensile stress and modulus of elasticity of the films. Samples prepared from denaturated collagen showed the higher ultimate tensile stress and the deformation at failure in comparison with those prepared from native collagen. The results suggest that we could expect successful application of the collagen/PVA biomaterial for tissue engineering.


2015 ◽  
Vol 35 (4) ◽  
pp. 377-390 ◽  
Author(s):  
Andrzej Ambroziak

Abstract This article describes the laboratory tests necessary to identify the mechanical properties of the polyvinylidene fluoride (PVDF)-coated fabrics named Precontraint 1202S and Precontraint 1302S. First, a short survey of the literature concerning the description of coated woven fabrics is presented. Second, the material parameters for PVDF-coated fabrics are specified on the basis of biaxial tensile tests. A comparison of the 1:1 biaxial and the uniaxial tensile tests results is also given. Additionally, biaxial cyclic tests were performed to observe the change of immediate mechanical properties under cyclic load. The article is aimed as an introduction to a comprehensive investigation of the mechanical properties of coated fabrics.


2021 ◽  
Vol 1026 ◽  
pp. 65-73
Author(s):  
Kai Zhu ◽  
Hong Wei Yan

Both microstructure inhomogeneity and mechanical property diversity along the thickness direction in rolled thick aluminum plates have been considered to have a remarkable impact on the performance and properties of the products made from the plates. In this study, scanning electron microscopy (SEM) and electron backscattered diffraction (EBSD) characterizations of microstructure and texture types along the thickness directions of Al7055 thick plate specimens prepared using two conditions, hot-rolling and solution-quenching, were performed. To examine the mechanical properties, uniaxial tensile tests were also carried out on specimens machined from both types of thick plates, using a layered strategy along the thickness direction. The results indicate that both the microstructure and mechanical properties are inhomogeneous under the two conditions. Furthermore, it is evident that there is a hereditary relationship between the mechanical properties of the two plates—areas with higher yield strength in the as-hot-rolled plate correspond to areas with the higher yield strength in the as-solution-quenched plate


Sign in / Sign up

Export Citation Format

Share Document