scholarly journals Effect of Preservation Period on the Viscoelastic Material Properties of Soft Tissues With Implications for Liver Transplantation

2010 ◽  
Vol 132 (10) ◽  
Author(s):  
Sina Ocal ◽  
M. Umut Ozcan ◽  
Ipek Basdogan ◽  
Cagatay Basdogan
Keyword(s):  
Liver Transplantation ◽  
Viscoelastic Material ◽  
Material Properties ◽  
Soft Tissues ◽  
Excitation Frequency ◽  
Viscoelastic Model ◽  
Relaxation Modulus ◽  
Bovine Liver ◽  
Dynamic Responses ◽  
Time Dependent

The liver harvested from a donor must be preserved and transported to a suitable recipient immediately for a successful liver transplantation. In this process, the preservation period is the most critical, since it is the longest and most tissue damage occurs during this period due to the reduced blood supply to the harvested liver and the change in its temperature. We investigate the effect of preservation period on the dynamic material properties of bovine liver using a viscoelastic model derived from both impact and ramp and hold experiments. First, we measure the storage and loss moduli of bovine liver as a function of excitation frequency using an impact hammer. Second, its time-dependent relaxation modulus is measured separately through ramp and hold experiments performed by a compression device. Third, a Maxwell solid model that successfully imitates the frequency- and time-dependent dynamic responses of bovine liver is developed to estimate the optimum viscoelastic material coefficients by minimizing the error between the experimental data and the corresponding values generated by the model. Finally, the variation in the viscoelastic material coefficients of bovine liver are investigated as a function of preservation period for the liver samples tested 1 h, 2 h, 4 h, 8 h, 12 h, 24 h, 36 h, and 48 h after harvesting. The results of our experiments performed with three animals show that the liver tissue becomes stiffer and more viscous as it spends more time in the preservation cycle.

Application of a Viscoelastic Model for Polyester Mooring

2010 ◽  
Author(s):  
J. W. Kim ◽  
J. H. Kyoung ◽  
A. Sablok
Keyword(s):  
Material Properties ◽  
Viscoelastic Model ◽  
Practical Method ◽  
Time Dependent ◽  
Mooring Line ◽  
New Model ◽  
Global Performance ◽  
Excitation Period ◽  
Linear Viscoelastic ◽  
Floating Platforms

A new practical method to simulate time-dependent material properties of polyester mooring line is proposed. The time-dependent material properties of polyester rope are modeled with a standard linear solid (SLS) model, which is one of the simplest forms of a linear viscoelastic model. The viscoelastic model simulates most of the mechanical properties of polyester rope such as creep, strain-stress hysteresis and excitation period-dependent stiffness. The strain rate-stress relation of the SLS model has been re-formulated to a stretch-tension relation, which is more suitable for implementation into global performance and mooring analyses tools for floating platforms. The new model has been implemented to a time-domain global performance analysis software and applied to simulate motion of a spar platform with chain-polyester-chain mooring system. The new model provides accurate platform offset without any approximation on the mean environmental load and can simulate the transient effect due to the loss of a mooring line during storm conditions, which has not been possible to simulate using existing dual-stiffness models.

Tests and Modeling of a New Vibration Isolation and Suppression Device

2017 ◽  
Vol 139 (12) ◽  
Author(s):  
Zhao-Dong Xu ◽  
Yeshou Xu ◽  
Qianqiu Yang ◽  
Chao Xu ◽  
Feihong Xu ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Energy Dissipation ◽  
Viscoelastic Material ◽  
Vibration Isolation ◽  
Dynamic Properties ◽  
Excitation Frequency ◽  
Dynamic Responses ◽  
Damping Capacity ◽  
Air Spring ◽  
Energy Dissipation Devices

Vibration is an environmental factor with hazardous effects on the instruments' precision, structural stability, and service life in engineering fields. Many kinds of energy dissipation devices have been invented to reduce the dynamic responses of structures and instruments due to environmental excitations. In this paper, a new kind of vibration isolation and suppression device with high damping performance, fine deformation recoverability, and bearing capacity for platform structures is developed, which is designed by considering the combination of the energy dissipation mechanisms of viscoelastic material, viscous fluid, and air spring. A series of dynamic properties tests on the device are carried out under different excitation frequencies and displacement amplitudes, and a mathematical model considering the coupling effects of energy dissipation of viscoelastic material, viscous liquid, and air spring is proposed. The research results indicate that the vibration isolation and suppression device has high damping capacity, and the proposed mathematical model can well describe the mechanical properties affected by excitation frequency and displacement amplitude.

Warpage Hysteresis Estimation of an Electronic Package During a Thermal Cycle

2015 ◽  
Author(s):  
Toru Ikeda ◽  
Akiko Ozaki ◽  
Takuya Hatao ◽  
Noriyuki Miyazaki
Keyword(s):  
Elastic Modulus ◽  
Viscoelastic Material ◽  
Material Properties ◽  
Thermal Cycle ◽  
Thermal Hysteresis ◽  
Relaxation Modulus ◽  
Circuit Board ◽  
Temperature Hysteresis ◽  
Mechanical Reliability ◽  
Electronic Package

The mechanical reliability of electronic packages is one of the critical problems in the reliability of electronic products in general. Estimating the warpage of an electronic package is useful for increasing its mechanical reliability. The warpage of an electronic package often shows a hysteresis curve during a thermal cycle. However, this hysteresis is difficult to simulate. We measured the master curves of the relaxation modulus using a Dynamic Mechanical Analyzer (DMA) before and after the first heating. Measured equilibrium elastic modulus after heating was two times higher than before heating. Curing rate of the resin before heating was already more than 99%. Change of elastic modulus in the range over 99% curing rate was much stronger than expected according to the conventional theory of rheology. We then analyzed the warpage of the specimen considering the change in the master curve of the relaxation modulus of the underfill resin. The hysteresis of the warpage of the bonded specimen was successfully predicted using the proposed method. In this study, we extended this method to a package on package (PoP). The PoP package also showed temperature hysteresis of the warpage. We considered the same viscoelastic material properties for the underfill resin. We also took the multi layered print circuit board and the viscoelastic material properties of solder resist into account. Simulated thermal hysteresis of the warpage of a PoP successfully corresponded with the measured warpage.

scholarly journals Using DMA to Simultaneously Acquire Young's Relaxation Modulus and Time-dependent Poisson's Ratio of a Viscoelastic Material

2014 ◽  
Vol 79 ◽  
pp. 153-159 ◽  
Author(s):  
Dao-Long Chen ◽  
Tz-Cheng Chiu ◽  
Tei-Chen Chen ◽  
Ming-Hua Chung ◽  
Ping-Feng Yang ◽  
...  
Keyword(s):  
Viscoelastic Material ◽  
Poisson’S Ratio ◽  
Relaxation Modulus ◽  
Time Dependent ◽  
Poisson's Ratio

scholarly journals Prediction model for early graft failure after liver transplantation using aspartate aminotransferase, total bilirubin and coagulation factor

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jinsoo Rhu ◽  
Jong Man Kim ◽  
Kyunga Kim ◽  
Heejin Yoo ◽  
Gyu-Seong Choi ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Prediction Model ◽  
Aspartate Aminotransferase ◽  
Graft Failure ◽  
Living Donor ◽  
Total Bilirubin ◽  
Deceased Donor ◽  
Time Dependent ◽  
Early Graft ◽  
Early Graft Failure

AbstractThis study was designed to build models predicting early graft failure after liver transplantation. Cox regression model for predicting early graft failure after liver transplantation using post-transplantation aspartate aminotransferase, total bilirubin, and international normalized ratio of prothrombin time was constructed based on data from both living donor (n = 1153) and deceased donor (n = 359) liver transplantation performed during 2004 to 2018. The model was compared with Model for Early Allograft Function Scoring (MEAF) and early allograft dysfunction (EAD) with their C-index and time-dependent area-under-curve (AUC). The C-index of the model for living donor (0.73, CI = 0.67–0.79) was significantly higher compared to those of both MEAF (0.69, P = 0.03) and EAD (0.66, P = 0.001) while C-index for deceased donor (0.74, CI = 0.65–0.83) was only significantly higher compared to C-index of EAD. (0.66, P = 0.002) Time-dependent AUC at 2 weeks of living donor (0.96, CI = 0.91–1.00) and deceased donor (0.98, CI = 0.96–1.00) were significantly higher compared to those of EAD. (both 0.83, P < 0.001 for living donor and deceased donor) Time-dependent AUC at 4 weeks of living donor (0.93, CI = 0.86–0.99) was significantly higher compared to those of both MEAF (0.87, P = 0.02) and EAD. (0.84, P = 0.02) Time-dependent AUC at 4 weeks of deceased donor (0.94, CI = 0.89–1.00) was significantly higher compared to both MEAF (0.82, P = 0.02) and EAD. (0.81, P < 0.001). The prediction model for early graft failure after liver transplantation showed high predictability and validity with higher predictability compared to traditional models for both living donor and deceased donor liver transplantation.

STRESS RELAXATION OF MAGNETORHEOLOGICAL FLUIDS

2002 ◽  
Vol 16 (17n18) ◽  
pp. 2655-2661
Author(s):  
W. H. LI ◽  
G. CHEN ◽  
S. H. YEO ◽  
H. DU
Keyword(s):  
Stress Relaxation ◽  
Viscoelastic Model ◽  
Relaxation Modulus ◽  
Damping Function ◽  
Mr Fluids ◽  
Large Step ◽  
Linear Viscoelastic ◽  
Predicted Values ◽  
Two Parameters ◽  
Step Strain

In this paper, the experimental and modeling study and analysis of the stress relaxation characteristics of magnetorheological (MR) fluids under step shear are presented. The experiments are carried out using a rheometer with parallel-plate geometry. The applied strain varies from 0.01% to 100%, covering both the pre-yield and post-yield regimes. The effects of step strain, field strength, and temperature on the stress modulus are addressed. For small step strain ranges, the stress relaxation modulus G(t,γ) is independent of step strain, where MR fluids behave as linear viscoelastic solids. For large step strain ranges, the stress relaxation modulus decreases gradually with increasing step strain. Morever, the stress relaxation modulus G(t,γ) was found to obey time-strain factorability. That is, G(t,γ) can be represented as the product of a linear stress relaxation G(t) and a strain-dependent damping function h(γ). The linear stress relaxation modulus is represented as a three-parameter solid viscoelastic model, and the damping function h(γ) has a sigmoidal form with two parameters. The comparison between the experimental results and the model-predicted values indicates that this model can accurately describe the relaxation behavior of MR fluids under step strains.

QUASI-LINEAR VISCOELASTIC MODELLING OF UNCURED PREPREGS UNDER COMPACTION

2021 ◽  
Author(s):  
SIDDHESH S. KULKARNI ◽  
KAMRAN A. KHAN ◽  
REHAN UMER
Keyword(s):  
Stress Relaxation ◽  
Relaxation Function ◽  
Soft Tissues ◽  
Volume Fraction ◽  
Time Dependent ◽  
Strain History ◽  
Manufacturing Processes ◽  
Fiber Volume ◽  
Consolidation Process ◽  
Thermoset Resin

Reinforcement compaction sometimes referred as consolidation process and is one of the key steps in various composite manufacturing processes such as autoclave and out-of-autoclave processing. The prepregs consist of semi-cured thermoset resin system impregnating the fibers. hence, the prepreg shows strong viscoelastic compaction response, which strongly depends on compaction speed and stress relaxation. modeling of time-dependent response is of utmost importance to understand the behavior of prepregs during different stages of composites manufacturing processes. The quasilinear viscoelastic (QLV) theory has been extensively used for the modeling of viscoelastic response of soft tissues in biomedical applications. In QLV approach, the stress relaxation can be expressed in terms of the nonlinear elastic function and the reduced relaxation function. The constitutive equation can be represented by a convolution integral of the nonlinear strain history, and reduced relaxation function. This study adopted a quasilinear viscoelastic modeling approach to describe the time dependent behavior of uncured-prepregs under compression. The model was modified to account for the compaction behavior of the prepreg under a compressive load. The deformation behavior of the prepreg is usually characterized by the fiber volume fraction, V . In this study, the material used was a 2/2 Twill weave glass prepreg (M26T) supplied by Hexcel® Industries USA. We performed a compaction experiment of the uncured prepreg at room temperature at different displacement rate and subsequent relaxation to describe the viscoelastic behavior of the prepreg. The model parameter calibration was performed using the trust-region-reflective algorithm in matlab to a selected number of test data. The calibrated model was then used to predict the rate dependent compaction and relaxation response of prepregs for different fiber volume fractions and strain rates.

Properties of Mouse Cutaneous Rapidly Adapting Afferents: Relationship to Skin Viscoelasticity

2004 ◽  
Vol 92 (2) ◽  
pp. 1236-1240 ◽  
Author(s):  
P. Grigg ◽  
D. R. Robichaud ◽  
Z. Del Prete
Keyword(s):  
Viscoelastic Material ◽  
Material Properties ◽  
Viscoelastic Properties ◽  
Mechanical Response ◽  
Loss Modulus ◽  
Multiple Logistic Regression Analysis ◽  
Rate Of Change ◽  
Volterra Model ◽  
Lower Sensitivity ◽  
Dynamic Stimuli

When skin is stretched, stimuli experienced by a cutaneous mechanoreceptor neuron are transmitted to the nerve ending through the skin. In these experiments, we tested the hypothesis that the viscoelastic response of the skin influences the dynamic response of cutaneous rapidly adapting (RA) neurons. Cutaneous RA afferent neurons were recorded in 3 species of mice (Tsk, Pallid, and C57BL6) whose skin has different viscoelastic properties. Isolated samples of skin and nerve were stimulated mechanically with a dynamic stretch stimulus, which followed a pseudo Gaussian waveform with a bandwidth of 0–60 Hz. The mechanical response of the skin was measured as were responses of single RA cutaneous mechanoreceptor neurons. For each neuron, the strength of association between spike responses and the dynamic and static components of stimuli were determined with multiple logistic regression analysis. The viscoelastic material properties of each skin sample were determined indirectly, by creating a nonlinear (Wiener–Volterra) model of the stress–strain relationship, and using the model to predict the complex compliance (i.e., the viscoelastic material properties). The dynamic sensitivity of RA mechanoreceptor neurons in mouse hairy skin was weakly related to the viscoelastic properties of the skin. Loss modulus and phase angle were lower (indicating a decreased viscous component of response) in Tsk and Pallid than in C57BL6 mice. However, RA mechanoreceptor neurons in Tsk and Pallid skin did not differ from those in C57 skin with regard to their sensitivity to the rate of change of stress or to the rate of change of incremental strain energy. They did have a decreased sensitivity to the rate of change of tensile strain. Thus the skin samples with lower dynamic mechanical response contained neurons with a somewhat lower sensitivity to dynamic stimuli.

A Method of Calculating the Dynamic Characteristics of Rubber Isolator

2013 ◽  
Vol 395-396 ◽  
pp. 1170-1173 ◽  
Author(s):  
Xiao Yan Guo ◽  
Jin Zhi Zhou ◽  
Da Peng Feng ◽  
Hou Min Li
Keyword(s):  
Dynamic Characteristics ◽  
Dynamic Property ◽  
Excitation Frequency ◽  
Viscoelastic Model ◽  
Elastic Model ◽  
Frequency Dependency ◽  
Plastic Model ◽  
Filled Rubber ◽  
Relative Errors ◽  
Rubber Isolator

The dynamic property of carbon filled rubber materials is related to pre-load, excitation frequency and amplitude etc. A model by superimposing an elastic model, a viscoelastic model and an elastic-plastic model is presented to model the dynamic property of a rubber isolator. In this paper, this approach is adopted to calculate the dynamic property of a rubber isolator. It is shown that the presented model can predict the amplitude and frequency dependency of a rubber isolator with small relative errors. The validity of this model is verified by experiment. The approach described in this paper can be used in the design and calculation for rubber isolators.

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