The Impact of Retroactivity on the Input/Output Static Characteristics of a Signaling Component

2010 ◽  
Author(s):  
A. C. Ventura ◽  
P. Jiang ◽  
A. J. Ninfa ◽  
L. Van Wassenhove ◽  
S. D. Merajver ◽  
...  
Keyword(s):  
Covalent Modification ◽  
Engineering Systems ◽  
Prior Work ◽  
Static Characteristics ◽  
Input Output ◽  
Input Stimulus ◽  
Biomolecular Systems ◽  
A Cell ◽  
The Impact ◽  
Signaling Components

In prior work, we have shown that just as in many engineering systems, impedance-like effects appear at the interconnection of biomolecular systems. These effects are called retroactivity, to extend the notion of impedance to biological systems. Signaling components, such as covalent modification cycles, play a central role in the transmission of signals within a cell and from outside the cell. They are typically found in highly interconnected architectures in which a component has several downstream clients. In this paper, we show that retroactivity from downstream targets decreases the sensitivity of response to an input stimulus.

The Impact of the Public Expenditure Cuts Policy on the Labor Market in Vietnam

2012 ◽  
pp. 22-46
Author(s):  
Huong Nguyen Thi Lan ◽  
Toan Pham Ngoc
Keyword(s):  
Labor Market ◽  
Computable General Equilibrium ◽  
Impact Evaluation ◽  
Public Expenditure ◽  
Computable General Equilibrium Model ◽  
Living Standard ◽  
Input Output ◽  
Policy Makers ◽  
The Public ◽  
The Impact

The purpose of this study is to evaluate the impact of public expenditure cuts on employment and income to support policies for the development of the labor mar- ket. Impact evaluation is of interest for policy makers as well as researchers. This paper presents a method – that is based on a Computable General Equilibrium model – to analyse the impact of the public expenditure cuts policy on employment and income in industries and occupations in Vietnam using macro data, the Input output table, 2006, 2008 and the 2010 Vietnam Household Living Standard Survey.

Estimating the impact of Bio-Economy using input-output table

2012 ◽  
Vol 26 (2) ◽  
pp. 59-86
Author(s):  
주원 ◽  
Lee Joo Rynag ◽  
Yoon-Jung Jung
Keyword(s):  
Input Output ◽  
Output Table ◽  
The Impact

Statistical Approaches to Structural Change in Regional Interindustry Models

1986 ◽  
Vol 18 (9) ◽  
pp. 1189-1207
Author(s):  
B Ó Huallacháin
Keyword(s):  
Structural Change ◽  
Structural Changes ◽  
Washington State ◽  
Multivariate Statistical Analyses ◽  
Input Output ◽  
Multivariate Statistical ◽  
State Data ◽  
System A ◽  
Statistical Approaches ◽  
The Impact

The conventional approach to assessing structural change in regional input – output tables is to measure the impact of coefficient change on the estimation of outputs and multipliers. The methods developed and tested in this paper focus exclusively on the coefficients. Univariate and multivariate statistical analyses can be used to identify and measure various types of changes ranging from coefficient instability to changes in interindustry relationships as a system. A distinction is made between structural changes in input relationships and those in output relationships. The methods are tested by using Washington State data for the years 1963 and 1967. The results are compared with previous analyses of change in these data.

scholarly journals Integrated Mechanistic Engineering Models and Macroeconomic Input-Output approach to Model Physical Economy for Evaluating the Impact of transition to Circular Economy

2021 ◽  
Author(s):  
Venkata Sai Gargeya Vunnava ◽  
Shweta Singh
Keyword(s):  
Circular Economy ◽  
Emerging Technologies ◽  
Low Carbon ◽  
Input Output ◽  
Zero Waste ◽  
Engineering Models ◽  
The Impact ◽  
Sustainable Transition

Sustainable transition to low carbon and zero waste economy requires a macroscopic evaluation of opportunities and impact of adopting emerging technologies in a region. However, a full assessment of current...

scholarly journals The Importance of Studying Health Behavior in Older Adults

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 827-827
Author(s):  
Jaime Hughes ◽  
Susan Hughes ◽  
Mina Raj ◽  
Janet Bettger
Keyword(s):  
Social Support ◽  
Older Adults ◽  
Behavior Change ◽  
Chronic Conditions ◽  
Population Level ◽  
Multiple Chronic Conditions ◽  
Prior Work ◽  
Time Changes ◽  
The Impact ◽  
Over Time

Abstract Behavior change is an inherent aspect of routine geriatric care. However, most research and clinical programs emphasis how to initiate behavior change with less emphasis placed on skills and strategies to maintain behaviors over time, including after an intervention has concluded. This presentation will provide an introduction to the symposium, including a review of prior work and our rationale for studying the critical yet overlooked construct of maintenance in older adults. Several key considerations in our work include the impact of multiple chronic conditions, declines in cognitive and functional capacity over time, changes in environmental context and/or social support, and sustainability of community and population-level programs and services.

Numerical Simulation of Heat Transfer Mechanisms in Spray Cooling

2010 ◽  
Author(s):  
Eelco Gehring ◽  
Mario F. Trujillo
Keyword(s):  
Heat Transfer ◽  
Heated Surface ◽  
Spray Cooling ◽  
Impingement Zone ◽  
Ongoing Work ◽  
Efficient Suppression ◽  
A Cell ◽  
Cooling Behavior ◽  
Free Surface Capturing ◽  
The Impact

A primary mechanism of heat transfer in spray cooling is the impingement of numerous droplets onto a heated surface. This mechanism is isolated in the present and ongoing work by numerically simulating the impact of a single train of FC-72 droplets employing an implicit free surface capturing methodology. The droplet frequency and velocity ranges from 2000–4000 Hz, and 0.5–2 m/s, respectively, with a fixed drop size of 239 μm. This gives a corresponding Weber and Reynolds range of 10–170 and 330–1300, respectively. Results show that the impingement zone is largely free of phase change effects due to the efficient suppression of the local temperature field well below the saturated value. Due in part to the relatively high value of the Prandtl number and the compression of the boundary layer from the impingement flow, a cell size on the order of 1 μm is necessary to adequately capture the heat transfer dynamics. It is shown that the cooling behavior increases in relation to increasing frequency and impact velocity, but is most sensitive to velocity. In fact, for sufficiently low velocities the calculations show that the momentum imparted on the film is insufficient to maintain a near stationary liquid crown. The consequence is a noticeable penalty on the cooling behavior.

scholarly journals An Input–Output Ex Ante Regional Model to Assess the Short-Term Net Effects of the 16 April 2016 Earthquake in Ecuador

2021 ◽  
Author(s):  
Jorge Salgado ◽  
José Ramírez-Álvarez ◽  
Diego Mancheno
Keyword(s):  
Natural Hazard ◽  
National Accounts ◽  
Input Output ◽  
Short Term ◽  
Ex Ante ◽  
The Impact ◽  
Consumption Demand ◽  
Two Sectors ◽  
Positive Effect

AbstractThe 16 April 2016 earthquake in Ecuador exposed the significant weaknesses concerning the methodological designs to compute—from an economic standpoint—the consequences of a natural hazard-related disaster for productive exchanges and the accumulation of capital in Ecuador. This study addressed one of these challenges with an innovative ex ante model to measure the partial and net short-term effects of a natural hazard-related catastrophe from an interregional perspective, with the 16 April 2016 earthquake serving as a case study. In general, the specified and estimated model follows the approach of the extended Miyazawa model, which endogenizes consumption demand in a standard input–output model with the subnational interrelations and resulting multipliers. Due to the country’s limitations in its regional account records the input–output matrices for each province of Ecuador had to be estimated, which then allowed transactions carried out between any two sectors within or outside a given province to be identified by means of the RAS method. The estimations provide evidence that the net short-term impact on the national accounts was not significant, and under some of the simulated scenarios, based on the official information with respect to earthquake management, the impact may even have had a positive effect on the growth of the national product during 2016.

scholarly journals Analytical Model for Estimating the Impact of Changing the Nominal Power Parameter in LTE

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
A. B. Vallejo-Mora ◽  
M. Toril ◽  
S. Luna-Ramírez ◽  
M. Regueira ◽  
S. Pedraza
Keyword(s):  
Analytical Model ◽  
Mobile Networks ◽  
Radio Resource Management ◽  
Estimation Accuracy ◽  
Model Assessment ◽  
Power Parameter ◽  
Management Procedure ◽  
Proposed Model ◽  
A Cell ◽  
The Impact

UpLink Power Control (ULPC) is a key radio resource management procedure in mobile networks. In this paper, an analytical model for estimating the impact of increasing the nominal power parameter in the ULPC algorithm for the Physical Uplink Shared CHannel (PUSCH) in Long Term Evolution (LTE) is presented. The aim of the model is to predict the effect of changing the nominal power parameter in a cell on the interference and Signal-to-Interference-plus-Noise Ratio (SINR) of that cell and its neighbors from network statistics. Model assessment is carried out by means of a field trial where the nominal power parameter is increased in some cells of a live LTE network. Results show that the proposed model achieves reasonable estimation accuracy, provided uplink traffic does not change significantly.

scholarly journals Un modèle de projection des prix utilisant les relations intersectorielles de l’économie canadienne

2009 ◽  
Vol 51 (1) ◽  
pp. 71-85
Author(s):  
R. Rioux
Keyword(s):  
Commodity Prices ◽  
Price Formation ◽  
Input Output ◽  
Price Model ◽  
Primary Input ◽  
Time Period ◽  
Statistics Canada ◽  
The Impact ◽  
Push Model ◽  
Input Prices

This paper describes a simple cost-push price model which has been developed at the Structural Analysis Division of Statistics Canada. This price model is a traditional input/output cost-push model which has been adapted to utilize the rectangular industry by commodity input/output tables for Canada. It can be considered as the "dual" of the output model. Instead of analysing the propagation of demand through the economic system, the price model serves to analyse the propagation of factor prices throughout the system. The purpose of such a price formation model is to determine the impact on industry selling prices and domestic commodity prices arising from a change in impart commodity prices and primary input prices. This price model is of a static type; it accepts no substitutions and its structure is quite rigid. It is considered as being an annual model although it can be used for a different time period. This model is fully operational and is widely used by many government and private agencies.

scholarly journals Stabilization of Polar Localization of a Chemoreceptor via Its Covalent Modifications and Its Communication with a Different Chemoreceptor

2005 ◽  
Vol 187 (22) ◽  
pp. 7647-7654 ◽  
Author(s):  
Daisuke Shiomi ◽  
Satomi Banno ◽  
Michio Homma ◽  
Ikuro Kawagishi
Keyword(s):  
Histidine Kinase ◽  
Fluorescent Protein ◽  
Adaptor Protein ◽  
Molecular Assembly ◽  
Covalent Modification ◽  
Polar Localization ◽  
Receptor Localization ◽  
A Cell ◽  
Covalent Modifications ◽  
Green Fluorescent

ABSTRACT In the chemotaxis of Escherichia coli, polar clustering of the chemoreceptors, the histidine kinase CheA, and the adaptor protein CheW is thought to be involved in signal amplification and adaptation. However, the mechanism that leads to the polar localization of the receptor is still largely unknown. In this study, we examined the effect of receptor covalent modification on the polar localization of the aspartate chemoreceptor Tar fused to green fluorescent protein (GFP). Amidation (and presumably methylation) of Tar-GFP enhanced its own polar localization, although the effect was small. The slight but significant effect of amidation on receptor localization was reinforced by the fact that localization of a noncatalytic mutant version of GFP-CheR that targets to the C-terminal pentapeptide sequence of Tar was similarly facilitated by receptor amidation. Polar localization of the demethylated version of Tar-GFP was also enhanced by increasing levels of the serine chemoreceptor Tsr. The effect of covalent modification on receptor localization by itself may be too small to account for chemotactic adaptation, but receptor modification is suggested to contribute to the molecular assembly of the chemoreceptor/histidine kinase array at a cell pole, presumably by stabilizing the receptor dimer-to-dimer interaction.

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