The Further Development of National Safety Assessment Standard for In-Service Pressure Equipment Containing Defects

2013 ◽  
Author(s):  
Shanshan Shao ◽  
Guodong Jia ◽  
Liang Sun ◽  
Hui Wang
Keyword(s):  
Economic Performance ◽  
Safety Assessment ◽  
Standard System ◽  
National Standard ◽  
Assessment Procedure ◽  
Assessment Techniques ◽  
International Structure ◽  
Assessment Standard ◽  
Further Development

The fitness-for-service assessment is widely used to demonstrate whether identified defects or in-service deterioration threaten the structure integrity of the pressure equipment. This article introduces the development of the Chinese national safety assessment standard. The assessment procedure and assessment techniques of current Chinese national safety assessment standard GB/T 19624-2004 are demonstrated, and the improvement is proposed. In order to maintain availability of aging equipment and enhance the long-term economic performance of in service pressure equipment, a new Chinese national safety assessment standard system is methodology proposed based on the analysis of some international structure integrity procedures or standards. A new national standard fitness-for-service which focuses on the evaluation of in-service damage and degeneration will be established while GB/T 19624 is applicable for general defects.

Safety Assessment—A Method for Determining the Performance of Alarm and Shutdown Systems for Chemical Plants

1968 ◽  
Vol 1 (4) ◽  
pp. T72-T79 ◽  
Author(s):  
G. Hensley
Keyword(s):  
Safety Assessment ◽  
Safety Analysis ◽  
Quantitative Approach ◽  
Assessment Procedure ◽  
Chemical Plants ◽  
Qualitative And Quantitative ◽  
Hazardous Chemical ◽  
Hazardous Condition

Safeguards, for costly and hazardous chemical plants, are often provided by means of alarm or automatic shutdown systems. The adequacy of this protection—which is a measure of the capability of the newly installed system in shutting down the plant on the occurrence of a hazardous condition, and its effectiveness over the long term (its reliability)—may be judged by an independent safety assessment. Both qualitative and quantitative aspects of safety analysis are involved in an assessment, the quantitative approach being of particular use where there is a need to compare the anticipated reliability of the proposed system with a numerically specified, reliability requirement. Some of the techniques used in the assessment procedure are discussed in the paper and, by way of example, the performance of a typical shutdown system is assessed and its adequacy judged against a hypothetical plant fault condition.

What are the areas for further research?

2001 ◽  
Vol 44 (9) ◽  
pp. 17-25
Author(s):  
J. Jiang
Keyword(s):  
Impact Assessment ◽  
Performance Criteria ◽  
National Standard ◽  
Current Status ◽  
Assessment Procedure ◽  
Sampling Techniques ◽  
Instrumental Performance ◽  
Air Dispersion ◽  
Further Development ◽  
Regulations And Guidelines

The introduction of a national standard on odour measurement presents a new challenge for Australian olfactometry laboratories to meet tough new instrumental performance and panellist performance criteria. It also raises issues for end users of olfactometry results. For examples regulatory authorities may need to review the current status of odour regulations and guidelines. The paper reviews major issues pertaining to four components in odour impact assessment: measurement of odour, sampling techniques, air dispersion modelling, and the development of assessment criteria. The paper identifies and discusses the resolution of issues that could have a significant effect on the outcomes of odour impact assessment. It is hoped that the paper will provide a useful guide for industry and environmental protection authorities in the further development of an odour impact assessment procedure.

AS INUNDAÇÕES DE 2009 NA AMAZÔNIA E SUAS RELAÇÕES COM O DESENVOLVIMENTO SUSTENTÁVEL: IMPACTOS AO PRODUTO INTERNO BRUTO MUNICIPAL

GEOgraphia ◽  
2018 ◽  
Vol 20 (43) ◽  
pp. 101
Author(s):  
Alex Santiago Nina ◽  
Cláudio Fabian Szlafsztein
Keyword(s):  
Sustainable Development ◽  
Correlation Analysis ◽  
Gross Domestic Product ◽  
Natural Disasters ◽  
Economic Performance ◽  
Domestic Product ◽  
Economic Losses ◽  
Palabras Clave ◽  
Linear Correlation Analysis

Nos últimos anos, tem aumentado a frequência dos desastres naturais na Amazônia, concomitantemente com a necessidade de estimar os seus prejuízos econômicos. Este trabalho tem como objetivo verificar qual é o tipo e a intensidade do impacto das inundações de 2009, consideradas as maiores já registradas na Amazônia, no crescimento do Produto Interno Bruto (PIB) municipal. A metodologia consistiu na análise de correlação linear entre o desempenho econômico e algumas variáveis referentes ao tipo de inundação e indicadores socioeconômicos. Os resultados mostram que as inundações bruscas são as mais problemáticas em longo prazo. As principais estratégias a serem adotadas perpassam pela inclusão de ações de mitigação de desastres naturais ao planejamento do desenvolvimento sustentável da Amazônia. Palavras-chave: Produto Interno Bruto. Inundação. Amazônia. THE 2009 FLOODS IN THE AMAZON AND ITS RELATIONSHIP WITH SUSTAINABLE DEVELOPMENT: IMPACT ON THE MUNICIPAL GROSS DOMESTIC PRODUCT Abstract: In the last years, have been increase the frequency of natural disasters in Amazon, concomitantly whit the need of estimate their economic losses. This work have the objective of check what is the type and intensity of 2009 floods impacts, considered the major already registered in Amazon, to the increase of municipal Gross Domestic Product (GDP). The methodology was the linear correlation analysis between the economic performance and some variable relative to inundation type and socioeconomics indicators. The results bring which the fast floods are the major problem in the long term. The means strategies to be adopted are the inclusion of natural disasters mitigation actions in plan of sustainable development of Amazon. Keywords: Gross Domestic Product. Flood. Amazon. LAS INUNDACIONES DE 2009 EN LA AMAZONÍA Y SU RELACIÓN CON EL DESARROLLO SOSTENIBLE: IMPACTO EN EL PRODUCTO INTERNO BRUTO MUNICIPAL Resumen: En los últimos años ha aumentado la frecuencia de los desastres naturales en la Amazonia, concomitantemente con la necesidad de estimar sus prejuicios económicos. Este trabajo tiene como objetivo verificar cual es el tipo y la intensidad del impacto de las inundaciones de 2009, consideradas las mayores ya registradas en la Amazonia, al crecimiento del Producto Bruto Interno (PBI) municipal. La metodología consistió el análisis de correlación linear entre el desempeño económico y algunas variables referentes al tipo de inundación e indicadores socioeconómicos. Los resultados muestran que las inundaciones bruscas son las mas problemáticas a largo plazo. Las principales estrategias a ser adoptadas pasan por la inclusión de acciones de mitigación de desastres naturales a la planificación del desarrollo sostenible de la Amazonia. Palabras clave: Producto Interno Bruto. Inundaciones. Amazonia. 

scholarly journals Applications, challenges, and needs for employing synthetic biology beyond the lab

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Sierra M. Brooks ◽  
Hal S. Alper
Keyword(s):  
Synthetic Biology ◽  
Great Promise ◽  
Long Term Storage ◽  
Autonomous Function ◽  
Recent Advances ◽  
Resource Limited ◽  
Major Application ◽  
Further Development ◽  
Probiotic Delivery

AbstractSynthetic biology holds great promise for addressing global needs. However, most current developments are not immediately translatable to ‘outside-the-lab’ scenarios that differ from controlled laboratory settings. Challenges include enabling long-term storage stability as well as operating in resource-limited and off-the-grid scenarios using autonomous function. Here we analyze recent advances in developing synthetic biological platforms for outside-the-lab scenarios with a focus on three major application spaces: bioproduction, biosensing, and closed-loop therapeutic and probiotic delivery. Across the Perspective, we highlight recent advances, areas for further development, possibilities for future applications, and the needs for innovation at the interface of other disciplines.

scholarly journals Sustaining Trade during COVID-19 Pandemic: Establishing a Conceptual Model Including COVID-19 Impact

2021 ◽  
Vol 13 (10) ◽  
pp. 5418
Author(s):  
Nashwan M. A. Saif ◽  
Jianping Ruan ◽  
Bojan Obrenovic
Keyword(s):  
International Trade ◽  
Bilateral Trade ◽  
Production Costs ◽  
Research Directions ◽  
Economic Distance ◽  
Conceptual Paper ◽  
Sudden Decrease ◽  
Further Development ◽  
Conceptual Research

The conceptual research aims to identify antecedents conducive to bilateral trade during the COVID-19 pandemic. Considering the relevance of bilateral trade for foreign policy and economy studies, there is a need for a renewed framework in times of extreme economic instability. As international commerce is essential for improving the country’s economy, we have examined how economic distance, population, trade percentage of GDP, exchange rate, and political changes interconnect and relate to COVID-19, influencing trade flows. This conceptual paper illustrates the likely impact of COVID-19 on international trade by exploring pandemics’ effects on standard trading parameters such as GDP, distance, policy stability, and population. We model the resulting shock as a multifaceted variable reflected in capital underutilization, manufacturing output decline, international trade costs inflation, production costs inflation, decrease in demand for certain services and shift from everyday needs towards activities that exclude the proximity between people, e.g., proclivity towards virtual market products. The sudden decrease in GDP and bilateral trade, as well as FDI, is amplified by further development of pandemics’ long-term consequences. We take COVID-19 to be a technological, financial, and policy shock significantly influencing international trade and economic development and argue that it will have a varying impact on diverse sectors and economies. The paper offers preliminary insight into the pandemic-related economics that are unfolding and deduce recommendations on positive changes in trading policy to fully leverage on arising trading opportunities and point to potential research directions.

scholarly journals Health-related quality of life in patients with chronic hepatitis C treated with sofosbuvir-based treatment at 1-year post-sustained virological response

2021 ◽  
Author(s):  
Akio Miyasaka ◽  
Yuichi Yoshida ◽  
Akiko Suzuki ◽  
Yasuhiro Takikawa
Keyword(s):  
Quality Of Life ◽  
Hepatitis C ◽  
National Standard ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Standard Values ◽  
Chronic Hcv

Abstract Purpose Long-term effects on patient health-related quality of life (HRQoL) after direct-acting antiviral (DAA) treatment for hepatitis C virus (HCV) are unknown. We assessed the impact of DAA-mediated HCV clearance on HRQoL from DAA initiation to 1 year after confirmed sustained virological response at 24 weeks post-treatment (SVR24). Methods HRQoL was evaluated using the eight-item Short Form Health Survey (SF-8). Chronic HCV-infected patients were treated for 12 weeks with sofosbuvir-based DAAs. SF-8 was administered at baseline, treatment cessation, SVR24, and 1-year post-SVR24. Results A total of 109 chronic HCV-infected patients were enrolled. The average SF-8 scores were higher than the Japanese national standard values for bodily pain (BP) and mental health at baseline and for general health at 1-year post-SVR24. None of the SF-8 scores differed significantly between baseline and 1-year post-SVR24. Regarding age, sex, liver status, and treatment regimen, the SF-8 scores at 1-year post-SVR24 were affected by only age; individuals aged < 65 years had significantly higher physical component score (PCS), physical functioning, role physical, and BP scores than older individuals. In the multivariable analysis, only age of ≥ 65 years was significantly associated with influencing PCS at 1-year post-SVR24. However, no significant factors were identified for mental component score. Conclusion Upon long-term assessment, although more factors trended higher than national standard values at 1-year post-SVR24 than at baseline, there were no significant changes within factors. As PCS tended to be associated with age, patients aged ≥ 65 years should be carefully monitored for PCS.

scholarly journals The Impact of COVID-19 on Hospitality Industry in Greece and Its Treasured Santorini Island

2021 ◽  
Vol 13 (14) ◽  
pp. 7906
Author(s):  
Nikola Medová ◽  
Lucie Macková ◽  
Jaromir Harmacek
Keyword(s):  
Social Impact ◽  
Tourism Sector ◽  
Challenges And Opportunities ◽  
Multiple Variables ◽  
Hospitality Sector ◽  
Tourism And Hospitality ◽  
The Impact ◽  
Further Development

This paper focuses on the dynamic of the recent upheaval in the tourism and hospitality sector due to the COVID-19 epidemic in Greece and Santorini island. It uses the case study of a country one-fourth of whose GDP consists of tourism. We compare the available statistical data showing the change in variables in the previous years with 2020 and look into the new challenges and opportunities posed by the drop in the numbers of visitors and flights. We focus mainly on the economic and social impact on the destination and possible future scenarios for further development in the area. Data show a significant effect of the pandemic on multiple variables, such as the long-term trend of the importance of tourism sector in GDP in Greece, the number of flights and visitors to Greece and Santorini island, and the contribution of tourism and travel to GDP. Based on the available data, we also construct three foresight scenarios that describe the possible futures for Santorini island in terms of the pandemic evolution. These scenarios may help various stakeholders and policymakers to be better prepared for different developments that may appear.

1 Final Report on the Safety Assessment of Isostearyl Neopentanoate

1985 ◽  
Vol 4 (3) ◽  
pp. 1-22 ◽  
Keyword(s):  
Test Data ◽  
Clinical Studies ◽  
Safety Assessment ◽  
Final Report ◽  
Cosmetic Products ◽  
Short And Long Term ◽  
Cosmetic Formulation

Isostearyl Neopentanoate, the ester of Isostearyl Alcohol and Neopentanoic Acid, is used in cosmetic products as an emollient at concentrations up to 50 percent. The undiluted ingredient at doses up to 4 ml/kg was shown to be relatively non-toxic in short-and long-term feeding studies. Test data from animal and clinical studies indicate the undiluted ingredient is neither an irritant nor a sensitizer. A cosmetic formulation containing 16 percent Isostearyl Neopentanoate produced no phototoxicity and no photoallergenicity. Mutagenicity, carcinogenicity, and teratogenicity data were not available. Isostearyl Neopentanoate was not considered to be a significant comedogenic agent. On the basis of available data, it is concluded that this ingredient is safe as a cosmetic ingredient in its present practices of use.

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