The Relationship Between Serum and Salivary Cortisol Levels in Response to Different Intensities of Exercise

2011 ◽  
Vol 6 (3) ◽  
pp. 396-407 ◽  
Author(s):  
Mitch D. VanBruggen ◽  
Anthony C. Hackney ◽  
Robert G. McMurray ◽  
Kristin S. Ondrak
Keyword(s):  
Salivary Cortisol ◽  
High Intensity ◽  
Repeated Measures ◽  
Recovery Period ◽  
Cycle Ergometer ◽  
Saliva Cortisol ◽  
Cortisol Responses ◽  
Cortisol Levels ◽  
The Relationship ◽  
Matched Samples

Purpose:The effect of exercise intensity on the tracking of serum and salivary cortisol responses was examined in 12 endurance-trained males (maximal oxygen uptake [VO2max] = 58.2 ± 6.4 mL/kg/min).Methods:Subjects rested for 30 min (control) and exercised on a cycle ergometer for 30 min at 40% (low), 60% (moderate), and 80% (high intensity) of VO2max on separate days. Serum and saliva samples were collected pretrial, immediately posttrial, and 30 min into the recovery period from each trial.Results:Cortisol responses increased significantly for both serum (40.4%; P = .001) and saliva (170.6%; P = .007) only in response to high-intensity exercise. Peak saliva cortisol occurred at 30 min of recovery, whereas peak serum was at the immediate posttrial sampling time point. The association between serum and saliva cortisol across all trials was examined using concordance correlation (Rc) analysis, which accounts for repeated measures. The overall correlation between serum and saliva cortisol levels in all matched samples was significant (Rc = 0.728; P = .001). The scatter plot revealed that salivary cortisol responses tracked closely to those of serum at lower concentrations, but not as well at higher concentrations.Conclusions:Findings suggest salivary measurements of cortisol closely mirror those in the serum and that peak salivary concentrations do not occur until at least 30 min into the recovery from intense exercise.

Plasma adrenocorticotropin and cortisol responses to brief high-intensity exercise in humans

1986 ◽  
Vol 61 (4) ◽  
pp. 1337-1339 ◽  
Author(s):  
M. J. Buono ◽  
J. E. Yeager ◽  
J. A. Hodgdon
Keyword(s):  
High Intensity ◽  
Plasma Cortisol ◽  
Exercise Bout ◽  
Cycle Ergometer ◽  
High Intensity Exercise ◽  
O2 Uptake ◽  
Plasma Acth ◽  
Cortisol Responses ◽  
Cortisol Levels ◽  
Exercise In Humans

The purpose of this study is to examine plasma cortisol and adrenocorticotropin (ACTH) levels following a brief high-intensity bout of exercise. Each subject (n = 6) performed a 1-min bout of exercise on a cycle ergometer at 120% of his maximum O2 uptake. Blood samples were collected at rest, immediately following the exercise bout, and at 5, 15, and 30 min postexercise. Mean (+/- SE) plasma ACTH levels increased significantly (P less than 0.05) from 2.2 +/- 0.4 pmol/l at rest to 6.2 +/- 1.7 pmol/l immediately following exercise. Mean (+/- SE) plasma cortisol levels increased significantly from 0.40 +/- 0.04 mumol/l at rest to 0.52 +/- 0.04 mumol/l at 15 min postexercise. These data show that brief high-intensity exercise results in significant increases in plasma cortisol and ACTH levels. Furthermore, the temporal sequence between the two hormones suggests that the increase in plasma cortisol levels following brief high-intensity exercise is the result of ACTH-induced steroidogenesis in the adrenal cortex.

scholarly journals Salivary cortisol as a non-invasive approach to assess stress in dystocic dairy calves

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Levente Kovács ◽  
Fruzsina Luca Kézér ◽  
Szilárd Bodó ◽  
Ferenc Ruff ◽  
Rupert Palme ◽  
...  
Keyword(s):  
Birth Weight ◽  
Body Condition ◽  
Salivary Cortisol ◽  
Sampling Period ◽  
Dairy Calves ◽  
Birth Process ◽  
Invasive Approach ◽  
Non Invasive ◽  
Saliva Cortisol ◽  
Cortisol Levels

AbstractThe intensity and the magnitude of saliva cortisol responses were investigated during the first 48 h following birth in newborn dairy calves which underwent normal (eutocic, EUT, n = 88) and difficult (dystocic, DYS, n = 70) calvings. The effects of parity and body condition of the dam, the duration of parturition, the time spent licking the calf, the sex and birth weight of the calf were also analyzed. Neonatal salivary cortisol concentrations were influenced neither by factors related to the dam (parity, body condition) nor the calf (sex, birth weight). The duration of parturition and the time spent licking the calf also had no effect on salivary cortisol levels. Salivary cortisol concentrations increased rapidly after delivery in both groups to reach their peak levels at 45 and 60 min after delivery in EUT and DYS calves, respectively supporting that the birth process means considerable stress for calves and the immediate postnatal period also appears to be stressful for newborn calves. DYS calves exhibited higher salivary cortisol concentrations compared to EUT ones for 0 (P = 0.022), 15 (P = 0.016), 30 (P = 0.007), 45 (P = 0.003), 60 (P = 0.001) and 120 min (P = 0.001), and for 24 h (P = 0.040), respectively. Peak levels of salivary cortisol and the cortisol release into saliva calculated as AUC were higher in DYS than in EUT calves for the 48-h of the sampling period (P = 0.009 and P = 0.003, respectively). The greater magnitude of saliva cortisol levels in DYS calves compared to EUT ones suggest that difficult parturition means severe stress for bovine neonates and salivary cortisol could be an opportunity for non-invasive assessment of stress during the early neonatal period in cattle.

scholarly journals Diurnal Salivary Cortisol in Sarcopenic Postmenopausal Women: The OsteoLaus Cohort

2021 ◽  
Author(s):  
Elena Gonzalez Rodriguez ◽  
Pedro Marques-Vidal ◽  
Bérengère Aubry-Rozier ◽  
Georgios Papadakis ◽  
Martin Preisig ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Salivary Cortisol ◽  
Population Based ◽  
Cross Sectional Study ◽  
Body Composition Assessment ◽  
Cross Sectional ◽  
X Ray ◽  
Free Cortisol ◽  
Cortisol Levels ◽  
The Relationship

AbstractSarcopenia, similar to hypercortisolism, is characterized by loss of muscle mass and strength. Cortisol circadian rhythm changes with aging (blunted late-day nadir values) were suggested to contribute to this decline. We aimed to explore the relationship between diurnal salivary cortisol values and sarcopenia diagnosis and its components in postmenopausal women. This is a cross-sectional study within the OsteoLaus population-based cohort in Lausanne (Switzerland). Participants had a body composition assessment by dual X-ray absorptiometry (DXA), a grip strength (GS) measure, and salivary cortisol measures (at awakening, 30 min thereafter, 11 AM (sc-11AM) and 8 PM (sc-8PM)). Associations between salivary cortisol and sarcopenia diagnosed by six different criteria (based on appendicular lean mass (ALM) assessed by DXA, and muscle strength by GS), and its components, were analyzed. 471 women aged > 50 years (63.0 ± 7.5) were included. Various definitions identified different participants as sarcopenic, who consistently presented higher salivary cortisol at 11 AM and/or 8 PM. There were no associations between salivary cortisol levels and ALM measures, either absolute or after correction to height squared (ALM index) or body mass index. GS was inversely correlated to sc-11AM (r = − 0.153, p < 0.001) and sc-8PM (r = − 0.118, p = 0.002). Each 10 nmol/l increase of sc-11AM, respectively sc-8PM, was associated with a GS decrease of 1.758 (SE 0.472) kg, respectively 2.929 (SE 1.115) kg. In postmenopausal women, sarcopenia is associated with higher salivary cortisol levels at 11 AM and 8 PM. An increase of daily free cortisol levels in the physiological range could participate to sarcopenia development by decreasing muscle function in postmenopausal women.

Relationship between levels of salivary cortisol with depression and suicidal ideation

2011 ◽  
Vol 26 (S2) ◽  
pp. 1631-1631 ◽  
Author(s):  
P. De Usabel Guzmán ◽  
M.J. Mota Rodríguez ◽  
A. Pampin Alfonso ◽  
J.B. Brenlla Gonzalez ◽  
M.J. Núñez ◽  
...  
Keyword(s):  
Suicidal Ideation ◽  
Salivary Cortisol ◽  
Public Health Problem ◽  
Demographic Variables ◽  
Major Public Health Problem ◽  
Santiago De Compostela ◽  
High Prevalence ◽  
Cortisol Levels ◽  
The Relationship

IntroductionSuicide is a major public health problem in most of the countries because it has a high prevalence in young people. It has been studied that high levels of cortisol are associated with depression and increase of the suicidal risk.ObjectiveTo analyze the relationship between cortisol levels in a population of university students and the questionnaire results for the Beck Depression Inventory (BDI).MethodThe sample was composed by 106 students of the Nursing School of Santiago de Compostela University. The 88.7% of the sample are women with a mean age of 21.50 + /−2.52, the 99% are unmarried. The protocol consisted in 3 sections: demographic variables, BDI questionnaire with spanish scale and determination of salivary cortisol levels. Statistical analysis was done with SPSS 15.ResultsThe are higher levels of salivary cortisol in students with a greater or equal score to 13 on the BDI with statistically significances differences (p = .000). Students with suicidal ideation (item 9 of the BDI) have highest rates of cortisol, with statistically significant differences (p = 0.001).ConclusionsThis study supports other researchs about the association between biological neuroendocrine markers and affective disorders. Explaining suicidal behavior could help us to prevent it by using early intervention strategies for vulnerable populations. They could also identify markers to establish the risk of suicide.

scholarly journals Serum Cortisol Seems To Be a More Appropriate Marker for Adrenocortical Reserve Evaluation in ACTH Test in Comparison to Salivary Cortisol

2014 ◽  
pp. 229-236 ◽  
Author(s):  
M. KOSÁK ◽  
V. HÁNA ◽  
M. HILL ◽  
K. ŠIMŮNKOVÁ ◽  
Z. LACINOVÁ ◽  
...  
Keyword(s):  
Salivary Cortisol ◽  
Repeated Measures ◽  
Reference Group ◽  
Free Fraction ◽  
Serum Cortisol ◽  
Coefficient Of Determination ◽  
Acth Test ◽  
Promising Alternative ◽  
Cortisol Levels ◽  
Experimental Values

Salivary cortisol reflects the free fraction of serum cortisol. Monitoring salivary cortisol may be a promising alternative method for assessing serum cortisol in some clinical situations. We aimed to compare the reliability of salivary vs. serum cortisol during ACTH test. 84 subjects (mean age 63.2; 24-89 years; n=66 males) suspected for adrenocortical insufficiency underwent an ACTH test. Patients were divided based on peak serum cortisol into hypocortical group with cortisol <500 nmol/l and to reference group cortisol >500 nmol/l. Median serum cortisol levels in reference group were 445, 766, and 902 nmol/l at 0, 30, and 60 minutes, respectively, and in hypocortical group were 256, 394, and 453 nmol/l. Median salivary cortisol levels were 19.02, 40.02, and 62.1 nmol/l in reference group, and 9.60, 14.08, and 13.28 nmol/l in hypocortical group. Obtained values showed good correlation between serum and salivary cortisol (p<0.0001). The percentage of explained variability R2 (coefficient of determination for linear model) representing a measure of agreement between experimental values and predictions for repeated measures ANOVA, was significantly higher (p=0.021) for serum cortisol (R2=93.4 %) when compared to the salivary cortisol (R2=89.3 %). A stronger discriminating power of serum versus salivary cortisol suggests that it seems to be slightly, but statistically significantly more appropriate marker of adrenocortical reserve in ACTH test.

scholarly journals Effects of high-intense resistance training on salivary cortisol in trained individuals: a systematic review (Efectos del entrenamiento de resistencia de alta intensidad sobre el cortisol salival en individuos entrenados: una revisión sistemática)

Retos ◽  
2021 ◽  
pp. 265-271
Author(s):  
Rogério Santos Aguiar ◽  
Gustavo Casimiro Lopes ◽  
Juliana Brandão Pinto de Castro ◽  
Vitor Ayres Prince ◽  
Mauro Lúcio Mazini Filho ◽  
...  
Keyword(s):  
Physical Activity ◽  
Systematic Review ◽  
Resistance Training ◽  
Salivary Cortisol ◽  
Large Scale ◽  
High Intensity Training ◽  
Saliva Cortisol ◽  
Revisión Sistemática ◽  
Cortisol Levels ◽  
Meta Analyses

  This study aimed to evaluate the effects of high-intensity training (HIT) on salivary cortisol levels in physically trained individuals. This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. The search for scientific articles was carried out on the Scopus and MEDLINE (via PubMed) databases with the terms resistance training, saliva, cortisol, and their synonyms. We included interventions with high-intense resistance training that analyzed the salivary cortisol levels in physically trained men and women. From the 399 articles found, eight studies met the inclusion criteria. A population of 135 physically trained men and 12 women is with an average age of 23.26 ± 3.10 years, body mass of 85.53 ± 12.68 kg, and height of 1.80 ± 0.04 m. The intervention period ranged from 3 to 15 weeks with the use of 1 to 5 sets of 5 to 10 repetitions. Most protocols have been shown to provide significant stimuli to increase the level of cortisol acutely (p<0.05). The practice of HIT seems to be an effective intervention to stimulate the increase in acute and chronic salivary cortisol levels and thus induce possible changes in physiological and hormonal levels. Moreover, cortisol seems to represent physical activity in some populations and may be useful in monitoring physiology in large-scale observational physical activity surveys. However, more research is needed to elucidate the effects of HIT on cortisol and adaptive results. Resumen. Este estudio tuvo como objetivo evaluar los efectos del entrenamiento de alta intensidad sobre los niveles de cortisol salival en individuos entrenados físicamente. Esta revisión sistemática siguió las recomendaciones de PRISMA. La búsqueda de artículos científicos se realizó en las bases Scopus y MEDLINE (vía PubMed) con los términos entrenamiento de resistencia, saliva, cortisol y sus sinónimos. Se incluyeron intervenciones con entrenamiento de resistencia de alta intensidad que analizaron los niveles de cortisol salival en hombres y mujeres entrenados físicamente. De los 399 artículos encontrados, ocho estudios cumplieron los criterios de inclusión. Una población de 135 hombres entrenados físicamente y 12 mujeres tiene una edad de 23,26±3,10 años, masa corporal de 85,53±12,68 kg y altura de 1,80±0,04 m. El período de intervención varió de 3 a 15 semanas con el uso de 1 a 5 series de 5 a 10 repeticiones. Se ha demostrado que la mayoría de los protocolos proporcionan estímulos significativos para aumentar el nivel de cortisol de forma aguda (p<0,05). La práctica de entrenamiento de alta intensidad parece ser una intervención eficaz para estimular el aumento de los niveles de cortisol salival agudo y crónico y así inducir posibles cambios en los niveles fisiológicos y hormonales. Además, el cortisol parece representar la actividad física en algunas poblaciones y puede ser útil para monitorear la fisiología en encuestas observacionales de actividad física a gran escala. Sin embargo, se necesita más investigación para dilucidar los efectos de entrenamiento de alta intensidad sobre el cortisol y los resultados adaptativos.

Subjective Anxiety Measurements and Cortisol Responses in Adults Who Stutter

1994 ◽  
Vol 37 (4) ◽  
pp. 760-768 ◽  
Author(s):  
Gordon W. Blood ◽  
Ingrid M. Blood ◽  
Stephanie Bennett ◽  
Kathleen C. Simpson ◽  
Elizabeth J. Susman
Keyword(s):  
Trait Anxiety ◽  
Salivary Cortisol ◽  
State Anxiety ◽  
Communication Apprehension ◽  
High Stress ◽  
The State ◽  
Self Report ◽  
Cortisol Responses ◽  
Anxiety Levels ◽  
Cortisol Levels

Anxiety, as measured by self-report inventories and salivary cortisol levels, was examined in 11 males who stutter and 11 males who do not stutter during baseline, low stress, and high stress sessions. During the high stress session salivary cortisol was significantly greater in persons who stutter than in persons who do not stutter. No significant differences were found between the two groups on the State-Anxiety Inventory, Trait-Anxiety Inventory, or the Personal Report of Communication Apprehension. Significant differences in anxiety levels among the baseline, low stress, and high stress sessions for both groups of subjects were found for the State-Anxiety Inventory. No other significant differences or relationships were found between the two groups.

scholarly journals The relationship between alexithymia and salivary cortisol levels in somatoform disorders

2008 ◽  
Vol 62 (5) ◽  
pp. 366-373 ◽  
Author(s):  
Francisco Pedrosa Gil ◽  
Martin Bidlingmaier ◽  
Nathan Ridout ◽  
Carl Eduard Scheidt ◽  
Samantha Caton ◽  
...  
Keyword(s):  
Salivary Cortisol ◽  
Somatoform Disorders ◽  
Cortisol Levels ◽  
The Relationship

Effects of Oral D-Ribose Supplementation on Anaerobic Capacity and Selected Metabolic Markers in Healthy Males

2003 ◽  
Vol 13 (1) ◽  
pp. 76-86 ◽  
Author(s):  
R.B. Kreider ◽  
C. Melton ◽  
M. Greenwood ◽  
C. Rasmussen ◽  
J. Lundberg ◽  
...  
Keyword(s):  
Exercise Capacity ◽  
High Intensity ◽  
Repeated Measures ◽  
Adenine Nucleotide ◽  
Average Power ◽  
Anaerobic Capacity ◽  
Cycle Ergometer ◽  
High Intensity Exercise ◽  
Anaerobic Exercise ◽  
Metabolic Markers

Oral D-ribose supplementation has been reported to increase adenine nucle-otide synthesis and exercise capacity in certain clinical populations. Theoretically, increasing adenine nucleotide availability may enhance high intensity exercise capacity. This study evaluated the potential ergogenic value of D-ribose supplementation on repetitive high-intensity exercise capacity in 19 trained males. Subjects were familiarized to the testing protocol and performed two practice-testing trials before pre-supplementation testing. Each test involved warming up for 5 min on a cycle ergometer and then performing two 30-s Wingate anaerobic sprint tests on a computerized cycle ergometer separated by 3 min of rest recovery. In the pre- and post-supplementation trials, blood samples were obtained at rest, immediately following the first and second sprints, and following 5 min of recovery from exercise. Subjects were then matched according to body mass and anaerobic capacity and assigned to ingest, in a randomized and double blind manner, capsules containing either 5 g of a dextrose placebo (P) or D-ribose (R) twice daily (10 g/d) for 5 d. Subjects then performed post-supplementation tests on the 6th day. Data were analyzed by ANOVA for repeated measures. Results revealed a significant interaction (p = .04) in total work output. Post hoc analysis revealed that work significantly declined (–18 ± 51 J) during the second post-supplementation sprint in the P group while being maintained in the R group (–0.0 ± 31 J). No significant interactions were observed in peak power, average power, torque, fatigue index, lactate, ammonia, glucose, or uric acid. Results indicate that oral ribose supplementation (10 g/d for 5 d) does not affect anaerobic exercise capacity or metabolic markers in trained subjects as evaluated in this study.

scholarly journals Performance Changes and Recovery Time in U20 and Older Handball Players after a High-Intensity Sprint Exercise

2021 ◽  
Vol 11 (11) ◽  
pp. 5301
Author(s):  
Stefanie Klatt ◽  
Melanie Kossmann ◽  
Laura Hottenrott ◽  
Alexander Ferrauti ◽  
Frowin Fasold
Keyword(s):  
High Intensity ◽  
Repeated Measures ◽  
Recovery Time ◽  
Perceived Exertion ◽  
Recovery Period ◽  
Jump Height ◽  
Sprint Exercise ◽  
Interval Exercise ◽  
Stress Levels ◽  
High Intensity Interval

This study used a single bout of repeated high-intensity sprint exercise as a variable to compare the performance and recovery time of handball players within a typical age range for team sport athletes. Two test groups (U20 players, n = 12, mean age = 18 years; senior players, n = 17, mean age = 27 years) were observed during and after their performance of a high-intensity interval exercise consisting of four sets of 6 × 40 m all-out change-of-direction sprints. U20 players outperformed senior players in all sprint sets. The groups’ physiological responses and perceived exertion and stress levels were measured immediately before and after the exercise and also after 24, 48, and 72 h. Repeated measures ANOVAs revealed no interaction effects between age and measurement time points on jump height, muscle soreness, and perceived stress levels after the high-intensity interval exercise. However, the U20 athletes showed marginally, but not statistically significant lower creatine kinase (CK) values than the seniors 72 h after the exercise. The vagal heart rate variability (HRV) parameter rMSSD indicated a faster recovery for the U20 athletes compared to the senior players 24 h after the sprint intervals. Overall, the results demonstrate that repeated sprint intervals do not differently affect the physical performance ability (i.e., jump height) of U20 and senior players. Single parameters related to the players’ ability to recover, such as CK and HRV values, show some variations as a function of age. Based on this, coaches may want to consider a longer recovery period after a high-intensity exercise for senior players compared to younger ones.

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