Combined Exercise Modulates Cortisol, Testosterone, and Immunoglobulin A Levels in Individuals Living With HIV/AIDS

2019 ◽  
Vol 16 (11) ◽  
pp. 993-999 ◽  
Author(s):  
Bruno P. Melo ◽  
Débora A. Guariglia ◽  
Rafael E. Pedro ◽  
Dennis A. Bertolini ◽  
Solange de Paula Ramos ◽  
...  
Keyword(s):  
Immunoglobulin A ◽  
Immunological Parameters ◽  
Hormonal Responses ◽  
Immunological Responses ◽  
Combined Exercise ◽  
Inflammatory Parameters ◽  
Significant Difference ◽  
Living With Hiv ◽  
Assessment Session ◽  
Hiv Aids

Background: Combined exercise (CE) has been recommended for individuals living with HIV/AIDS (ILWHA) under antiretroviral therapy. However, depending on the intensity and duration, physical exercise may occasionally increase inflammatory parameters and reduce immunological responses that if not reversed, cause health injury specifically in this population. Information about immunological and hormonal responses after CE in ILWHA has not been completely elucidated. Therefore, the aim is to verify the acute effects of CE on cortisol, testosterone, immunoglobulin A, and pro-inflammatory and anti-inflammatory cytokines over 24 hours in ILWHA. Methods: Noninfected individuals and ILWHA undergone 5 sessions of CE prior to the acute assessment session. Seventy-two hours after the last session, the subjects were submitted to one session of CE (aerobic exercise: 25 min at 60–70% reserve heart rate and resistance exercise: 3 sets of 15 maximum repetitions of 6 exercises). Saliva samples were collected before, immediately, 6 and 24 hours after CE. Results: CE reduced cortisol (6 h: 2.54 [0.58] vs 0.65 [0.22] pg·mL−1; P = .02), increased testosterone (all moments) and immunoglobulin A levels (24 h: 255.3 [44.7] vs 349.2 [41.9] μm·mL−1; P = .01) without significant difference in cytokines levels in ILWHA. Conclusion: CE modulates cortisol, testosterone, and immunoglobulin A levels without the change in immunological parameters in ILWHA.

PERAN WARGA PEDULI AIDS CAHAYA CARE TUREN DALAM MENINGKATKAN KUALITAS HIDUP ODHA

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Tri Nurhudi Sasono
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Drugs ◽  
P Value ◽  
People Living With Hiv ◽  
Purposive Sampling ◽  
Significant Difference ◽  
Development Goals ◽  
Living With Hiv ◽  
Hiv Aids

Abstract : Indicator of the health welfare through Sustanable Development Goals (SDGs) is to reduce the incidence of HIV-AIDS, decrease the rate of the epidemic and maintain the quality of life of people living with HIV-AIDS (PLWHA). Trend cases of HIV-AIDS is the most recent spread among people, especially housewives. In Malang until 2015 found 278 Housewife of 409 cases of AIDS. The prevalence of HIV-AIDS in Malang Regency is ranked second after Surabaya city in East Java. For the importance of public participation and citizen care AIDS Cahaya Care Turen take responsibility for the condition. Determination Rule Goverment number 2 2015 year on the Participation of the community response to HIV-AIDS in Malang as a legal rule. Concerned Citizens activities AIDS (WPA). WPA Cahaya Care Turen is increases HIV risk and quality of life PLWHA. The purpose of this study was to determine the role of Citizens AIDS Cahaya Care Quality of Care Turen against people living with HIV in Puskesmas Turen Malang. The study design using a quasi-experimental, with purposive sampling using a sampling technique. Total number of research subjects 23. Based on test results obtained with the Wilcoxon p value <0.005, which means that there is a significant difference before and after PLWHA joining participated in the WPA Cahaya Care Turen. The conclusion of this study is WPA activities involving people living with HIV and at risk groups can optimize compliance with antiretroviral drugs that have an impact on improving the quality of life of PLHIV. Suggestions in this research is done WPA Program activities are structured and ongoing cross-sector in order to improve the quality of life and empower PLWHA.Keywords : WPA Cahaya Care Turen, Quality of life, PLWHA Abstrak : Salah satu indikator kesejahteraan kesehatan melalui Sustanable Development Goals (SDGs) adalah menekan angka kejadian HIV-AIDS, menurunkan laju epidemik dan mempertahankan kualitas hidup Orang dengan HIV-AIDS (ODHA). Trend kasus HIV-AIDS terkini terbanyak adalah menjangkit dikalangan masyarakat khususnya pada ibu rumah tangga. Kabupaten Malang sampai dengan tahun 2015 ditemukan 278 Ibu Rumah Tangga dari 409 kasus AIDS. Prevalensi HIV-AIDS di Kabupaten Malang ini merupakan peringkat kedua di Jawa Timur setelah Kota Surabaya. Untuk itu pentingnya peran serta masyarakat dan warga peduli AIDS Cahaya Care Turen ikut bertanggung jawab terhadap kondisi tersebut. Penetapan Peraturan Bupati Malang no.2 th.2015 tentang Peran serta masyarakat penanggulangan HIV-AIDS di Kabupaten Malang diharapkan dapat mengurangi risiko penularan HIV dan meningkatkan kualitas hidup ODHA. Tujuan dari penelitian ini adalah untuk mengetahui Peran Warga Peduli AIDS Cahaya Care Turen terhadap Kualitas ODHA Di Wilayah Kerja Puskesmas Turen Kabupaten Malang. Desain penelitian menggunakan quasi eksperimen, dengan teknik sampling menggunakan purposive sampling. Jumlah subyek penelitian sejumlah 23. Berdasarkan hasil uji dengan Wilcoxon didapatkan nilai p value < 0.005 yang berarti bahwa terdapat perbedaan bermakna sebelum dan sesudah ODHA bergabung mengikuti kegiatan WPA Cahaya Care Turen. Kesimpulan dalam penelitian ini adalah kegiatan WPA dengan melibatkan ODHA dan kelompok beresiko dapat mengoptimalkan kepatuhan obat ART sehingga berdampak terhadap peningkatan kualitas hidup ODHA. Saran dalam penelitian ini adalah dilakukannya Program kegiatan WPA yang terstruktur dan berkesinambungan lintas sektor guna meningkatkan kualitas hidup dan memberdayakan ODHA.     Kata kunci : WPA Cahaya Care Turen, kualitas hidup, ODHA

scholarly journals Food consumption and nutritional status of people living with HIV/AIDS (PLWHA): a case of Thika and Bungoma Districts, Kenya

2009 ◽  
Vol 13 (4) ◽  
pp. 475-479 ◽  
Author(s):  
Elizabeth Nafula Kuria
Keyword(s):  
Nutritional Status ◽  
Food Consumption ◽  
Dietary Habits ◽  
Well Being ◽  
Hiv Positive ◽  
People Living With Hiv ◽  
Cross Sectional ◽  
Significant Difference ◽  
Living With Hiv ◽  
Hiv Aids

AbstractObjectiveTo establish the food consumption, dietary habits and nutritional status of people living with HIV/AIDS (PLWHA) and adults whose HIV status is not established.DesignCross-sectional descriptive survey.SettingThika and Bungoma Districts, Kenya.SubjectsA random sample of 439 adults; 174 adults living with HIV/AIDS and 265 adults whose HIV/AIDS status was not established in Thika and Bungoma Districts.ResultsMajority of PLWHA consume foods that are low in nutrients to build up the immune system and help maintain adequate weight, and there is little variety in the foods they consume. More adults who are HIV-positive are undernourished than those whose status is not established. Of the HIV-positive adults, those with a BMI of ≤18·5 kg/m2 were 23·6 % (Thika 20·0 % and Bungoma 25·7 %) while of the adults whose status is not established those with BMI ≤ 18·5 kg/m2 were 13·9 % (Thika 9·3 % and Bungoma 16·7 %).ConclusionsAdults who are HIV-positive are more likely to be undernourished than those whose status is not established, as there is a significant difference (P = 0·000) between the nutritional status (BMI) of PLWHA and those whose HIV/AIDS status is not established. PLWHA consume foods that are low in nutrients to promote their nutritional well-being and health.

scholarly journals The Cytopathological and Molecular Aspects of Dysplasic Lesions of the Cervix: Particularities to Patients Living with Hiv Followed at Panzi General Reference Hospital

2019 ◽  
Vol 5 (3) ◽  
pp. 120-126
Author(s):  
Nyakio Olivier ◽  
◽  
Kibukila Fabrice ◽  
Chasinga Tchass ◽  
Gad Murenz ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Clinical Stage ◽  
Breast Cancer Mortality ◽  
Hiv Positive ◽  
Incidence And Mortality ◽  
Significant Difference ◽  
Cytological Abnormalities ◽  
Molecular Aspects ◽  
Living With Hiv ◽  
Hiv Aids

Introduction: Cervical cancer is one of the most common cancers and takes the second place among women's cancers in terms of incidence and the first place in terms of breast cancer mortality. Its incidence and mortality are significantly increased in patients living with HIV / AIDS. The purpose of this work is to describe the cytopathological and molecular aspects of cervical dysplasia in HIV-positive women in our environment and to look for some associated factors, in particular the degree of immunosuppression and the clinical stage. Methodology: This was a cross-sectional, descriptive, and analytical study of cervical-uterine smears (n = 111) and human papillomavirus genotyping (n = 73) in HIV-infected patients received from January 2018 to December 2018 at Panzi GRH (South Kivu, DR Congo). The data analysis was done using SPSS statistics 20 software. Results: The average age of the patients was 42.25 ± 10.42 years. The cervical-uterine smear (CUS) was normal in 82.9% of cases and cytological abnormalities were found in 13.5% of cases. The majority of patients were in WHO stages I (45.9%) and II (45.0%) of HIV infection and had a CD4 count greater than 500 cells / mm3 in 47.9% of patients. Among the 73 patients who had been tested for HPV infection, 35 (47.9%) were positive. The most common carcinogenic genotype among HPV positive patients was 18-45 (17.1%). There was not a significant difference in carcinogenic genotypes and intraepithelial lesions as a function of WHO clinical stages (p = 0.3819 and p = 0.7945). Conclusion: The coexistence between HIV and HPV infections seems to be strongly associated with the occurrence of cervical cytological abnormalities in our sample study. Hence the need, on the one hand, for a national policy for early detection of cervical cancer in all patients living with HIV / AIDS, and on the other hand, for deepened studies at the international level for the tuning of a plurigenic vaccine containing all oncogenic genotypes, those one that are geographically widespread (genotypes 16 and 18) are not more common to HIV-positive patients in our study environment

scholarly journals Immunological Responses and Survival Outcome in HIV and SARS-CoV-2 Coinfected Patients

2021 ◽  
Vol SP (2) ◽  
Author(s):  
Uzma A. Jilani ◽  
Zulhabri Othman ◽  
Syed A. Jilani
Keyword(s):  
Immune Responses ◽  
Current Knowledge ◽  
People Living With Hiv ◽  
Immunological Responses ◽  
Host Immune Responses ◽  
Acute Infections ◽  
Living With Hiv ◽  
The Impact ◽  
Special Subgroup ◽  
Hiv Aids

The coronavirus disease 2019 (COVID‐19) has created a worldwide crisis, raising fears and concerns regarding clinical outcomes in patients with comorbidities. Some of the highly prevalent communicable and non-communicable diseases worldwide are cardiovascular diseases, diabetes, HIV/AIDS, and hepatitis B and C, which reduce the host immune responses to concurrent acute infections. Despite over 170 million confirmed cases of COVID‐19 worldwide as of 24 June 2021, insufficient data is reporting the prognosis of HIV and SARS-CoV-2 co‐infection. This narrative review aims to present current knowledge on the impact of SARS-CoV-2 on people living with HIV/AIDS, in terms of immunological responses and clinical outcome. Although some studies have been performed and are in progress to determine the impact of SARS-CoV-2 infection on patients living with HIV/AIDS, controversies still exist whether COVID-19 severity and mortality are higher among this special subgroup or similar to the general population.

scholarly journals Association between HIV/AIDS Knowledge and Attitudes among African American Undergraduate Students in Jackson, Mississippi

2020 ◽  
pp. 29-40 ◽  
Author(s):  
Prince Onyekachi Andrew ◽  
Azad R. Bhuiyan ◽  
Jung Hye Sung ◽  
Anthony Mawson ◽  
Mohammad Shahbazi
Keyword(s):  
African American ◽  
Undergraduate Students ◽  
Hiv And Aids ◽  
Negative Attitudes ◽  
Knowledge And Attitudes ◽  
Positive Attitudes ◽  
Significant Difference ◽  
Aids Knowledge ◽  
Living With Hiv ◽  
Hiv Aids

Objective: This study aimed to determine HIV/AIDS knowledge level, attitudes toward individuals living with HIV/AIDS and to explore the relationship between HIV/AIDS knowledge and attitudes among African American undergraduates in Jackson, Mississippi. Methods:  A cross-sectional method was used in this study. A total of 400 students were randomly selected from Jackson State University undergraduate students. Data were collected by using a self-administered questionnaire on HIV/AIDS knowledge and their attitudes toward individuals living with HIV and AIDS. Results: Most of the students (96.5%) had good knowledge about HIV/AIDS, while some students had some misconceptions about HIV infection transmission. There was no significant difference between male and female students on HIV/AIDS knowledge in this study (χ2 = 3.05; P = 0.08). Most of the study participants (87.8%) showed positive attitudes toward individuals living with HIV/AIDS. However, there were some negative attitudes toward individuals living with HIV/AIDS among participants of this study. Male participants expressed more negative attitudes compared to female participants (19.1% vs. 8.5%, χ2 = 9.6; P < 0.002). HIV/AIDS knowledge was significantly associated with positive attitudes toward people living with the disease (p= 0.019, Pearson’s χ2 = 7.431). Conclusions:  In general, we concluded that most students (96.5%) in this study demonstrated high levels of HIV/AIDS knowledge and positive attitudes (87.8%). There was an association between knowledge of the disease and positive attitudes toward HIV/AIDS patients. However, there were HIV/AIDS knowledge gaps, misconceptions, and intolerant attitudes toward HIV positive patients also identified in this study. Hence, this study calls for more robust and age-appropriate HIV/AIDS awareness education programs geared towards reducing the impacts of negative attitudes toward individuals living with the disease, eliminating the gaps in HIV/AIDS knowledge and misconceptions identified in this study.

scholarly journals STIGMA TOWARDS PEOPLE LIVING WITH HIV/AIDS AMONG COUNSELING OFFICERS IN SOUTH SULAWESI, INDONESIA

2018 ◽  
Vol 4 (6) ◽  
pp. 552-558
Author(s):  
Abd Risal ◽  
Andi Masyitha Irwan ◽  
Elly Lilianty Sjattar
Keyword(s):  
Descriptive Analysis ◽  
Sampling Technique ◽  
Mean Value ◽  
People Living With Hiv ◽  
Voluntary Counseling And Testing ◽  
South Sulawesi ◽  
Significant Difference ◽  
The Mean ◽  
Living With Hiv ◽  
Hiv Aids

Background: Human Immunodeficiency Virus (HIV) / Acquired Immunodeficiency Syndrome (AIDS) has been a global problem nowadays. To reduce its spread, Voluntary Counseling and Testing (VCT) and Provider-Initiated Testing and Counseling (PITC) have been provided. However, these interventions remain ineffective to discover new cases, as the stigma among health officers may exist.Objective: To compare the stigma towards people living with HIV/AIDS between VCT and PITC officers.Methods: This was a descriptive comparative conducted in Makassar City, Parepare City and Sidenreng Rappang Regency, South Sulawesi Province Indonesia. There were 139 samples were selected using convenience sampling technique, which consisted of 66 VCT counseling officers and 73 PITC officers. The questionnaire from Health Policy Project in Thailand was used to measure the HIV/AIDS related-stigma. Data were analyzed using descriptive analysis and Mann Whitney test. Results: Findings show that there was a statistically significant difference in stigma between the group of VCT and PITC on people living with HIV/AIDS (PLWHA), which the mean of stigma in the PITC group (73.07) was higher than the mean value in the VCT group (66.61). Conclusion: There is a significant difference in stigma between VCT and PITC officers towards PLWHA. It is suggested that PITC curriculum should be evaluated and supervision and monitoring in both VCT and PITC groups should be implemented regularly to reduce the stigma towards PLWHA.

Assessing the measurement invariance of the CESD-10 and Beck anxiety inventory (BAI) questionnaires across people living with HIV/AIDS and healthy people

2019 ◽  
Author(s):  
Zahra Bagheri ◽  
Pegah Noorshargh ◽  
Zahra Shahsavar ◽  
Peyman Jafari
Keyword(s):  
Measurement Invariance ◽  
Depression Scale ◽  
Therapeutic Interventions ◽  
Beck Anxiety Inventory ◽  
People Living With Hiv ◽  
Healthy Individuals ◽  
Real Difference ◽  
Significant Difference ◽  
Living With Hiv ◽  
Hiv Aids

Abstract Background Recently, extensive research has been reported the higher rate of depression and anxiety among people living with HIV/AIDS (PLWHAs) as compared to general population. However, no single study has been carried out to investigate whether this disparity is a real difference or it happens due to lack of measurement invariance. This study aims to assess the measurement invariance of the Beck Anxiety Inventory (BAI) and 10-item Centre for Epidemiological Studies Depression Scale (CESD-10) questionnaires across PLWHAs and healthy individuals.Methods One hundred and fifty PLWHAs and 500 healthy individuals filled out the Persian version of the BAI and CES-D10 questionnaires. Multi-group multiple-indicators multiple-causes model (MG-MIMIC) was used to assess measurement invariance across PLWHAs and healthy people.Results Our findings revealed that PLWHAs and healthy individuals perceived the meaning of all the items in the BAI and CESD-10 questionnaires similarly. In addition, although depression scores were significantly higher in PLWHAs as opposed to healthy individuals, no significant difference was observed in anxiety scores of these two groups.Conclusions The current study suggests that the BAI and CESD-10 are invariant measures across PLWHAs and CESD-10 which can be used for meaningful cross-group comparison. Therefore, in comparison to healthy individuals, higher depression scores of PLWHAs is a real difference. It is highly recommended that health professionals develop therapeutic interventions and psychological supports to promote the mental health of PLWHAs which alleviate their depressive symptoms.

scholarly journals Quality Of Life and Self-Esteem among People Living With HIV/AIDS

2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Mr. Chandrakanth.B.K ◽  
Dr. Shanmuk Kamble
Keyword(s):  
Quality Of Life ◽  
Self Esteem ◽  
People Living With Hiv ◽  
Care And Support ◽  
District Hospitals ◽  
Significant Difference ◽  
The Difference ◽  
Living With Hiv ◽  
Hiv Aids

Purpose of this study is to investigate the difference in quality of life and self-esteem of People living with HIV/AIDS. 2X2 Research design was applied, among a sample of 120 HIV-infected persons receiving treatment, care, and support from district hospitals of Karnataka state. QOL was assessed using the HAT (QOL)-26 tools, and self-esteem scale was used. Results found that there is significant difference in quality of life among people living with HIV / AIDS, and there is significant difference in self-esteem among people living HIV/AIDS. It is also found that there is significant and positive correlation between quality of life and self-esteem among people living with HIV/AIDS.

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