scholarly journals AB1034 DEPRESSION AND ANXIETY IN FAMILIAL MEDITERRANEAN FEVER

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1808.2-1809
Author(s):  
D. Karatas ◽  
Z. Öztürk ◽  
D. Cekic ◽  
Z. Yuertsever ◽  
Ü. Erkorkmaz ◽  
...  

Background:Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disease characterized by recurrent attacks of fever, peritonitis, pleuritis, arthritis, and skin eruption (1). It is shown by studies that chronic diseases like diabetes mellitus, chronic heart disease, hypertension which other than inflammatory – rheumatologic disease increase depression and anxiety (2). There are a few studies evaluating depression and anxiety in FMF patients, and these results are conflicting (3,4).Objectives:To assess the frequency of depression and anxiety in patients with Familial Mediterranean Fever (FMF)Methods:In this study, 77 FMF patients aged 18 and over who were followed up in Sakarya University Education and Research Hospital, Department of Rheumatology, and 78 healthy volunteers aged 18 and over as thecontrol group. Beck depression scale and Beck anxiety scale were used to depression and anxiety, respectively. Beck’sdepression scale was evaluated as 9 and below normal, 10-16 mild depression, 17-29 moderate depression, 30-63 severe depression. Beck anxiety scale was evaluated as 0-8 normal, 8-15 mild anxiety, 16-25 moderate anxiety, 26 and above severe anxiety.FMF disease severity was determined by Pras scoring.Results:The study group, comprised 77 diagnosed with FMF with a meanage of 37.18 and a control group comprised of 78 healthy controls (C) with a meanage of 35.32 (p=0,058). İn studygroup (P) %63.6, control group (C) %53.8 as female. %36.4 of thestudy group(C), %46.2 of the control group are male. (p=0,216). The prevalence of depression was significantly higher in FMF patients compared to the control group (in order P;C: normal %24,7; %47,4, mild depression: %40.3; %26.9, moderate depression %26; %19.2, severe depression %11.7; %6.4 p<0.015). Similarly in depression results; the prevalence of anxiety was significantly higher in FMF patients compared to the control group (in order P;C normal %23,4; %57.7, mild anxiety %26; %20.5, moderate anxiety %26; %15.4, severe anxiety %24.4; %6.4 p<0,001). Depression status was not correlated with FMF disease severity (p=0.645). A correlation was found between FMF severity and anxiety which it is which was found statistically significant (p=0.005).There was no relationship between erythrocyte sedimentation rate and C-reactive protein with depression and anxiety.Conclusion:Both anxiety and depression frequency are increased in FMF patients compared to healthy controls.References:[1]Livneh A, Langevitz P, Zemer D et al. (1997) Criteria for the diagnosis of familial Mediterranean fever. Arthritis Rheum 40 (10), 1879–85.[2]Alonso J, Ferrer M, Gandek B, Ware JE Jr, Aaronson NK, Mosconi P, Rasmussen NK, Bullinger M, Fukuhara S, Kaasa S, Leplège A, IQOLA Project Group (2004) Health-related quality of life associated with chronic conditions in eight countries: results from the International Quality of Life Assessment (IQOLA) Project. Qual Life Res 13:283–298[3]Makay B, Emiroglu N, Unsal E (2010) Depression andanxiety in children and adolescents with familial Mediterranean fever. Clin Rheumatol 29, 375–9.[4]Giese A, Ornek A, Kilic L, Kurucay M, Sendur S. N., Lainka E, Henning B. F. Anxiety and depression in adult patients with familialMediterranean fever: a study comparing patients living in Germany and Turkey. International Journal of Rheumatic Diseases 2017; 20: 2093–2100Disclosure of Interests:None declared

2020 ◽  
Vol 26 (4) ◽  
pp. 227-236
Author(s):  
Irma Visoso Salgado ◽  
Jayson Leonel Moncada Mendoza ◽  
Hugo Mendieta Zerón

Background. Pregnancy is an important predisposition period to develop anxiety and depression, with a direct impact on the woman’s offspring. The aim of this study was to report the correlation between depression and anxiety in pregnant women and its association with the marital status and age. Materials. A descriptive, retrospective and cross-sectional study was conducted in the outpatient care of the Psychology Service at the “Mónica Pretelini Sáenz” Maternal Perinatal Hospital (HMPMPS), Toluca, Mexico, from June 2012 to March 2019. As routine, the Beck Depression Inventory (BDI-II) and the Beck Anxiety Inventory-Trait (BAIT), were applied to all women seeking attention at the HMPMPS. Only pregnant patients were selected for this study, with the women referred for the first time to the external Psychology Clinic as inclusion criteria. Pearson’s correlation coefficient and the frequency of cases for age, BDI-II, and BAIT were obtained using the IBM SPSS Statistics ® v.23 software. Results. The study included 2947 pregnant patients with a mean age of 28.6 ± 6.9 years. Of these, 2616 (88.8%) presented with mild anxiety, 269 (9.1%) with moderate, and 62 (2.1%) with severe anxiety. On the other hand, 2149 (72.9%) patients presented with minimal depression, 341 (11.6%) mild depression, 268 (9.1%) moderate depression, and 189 (6.4%) had severe depression. The correlations between age and BDI-II was –0.026 (P = 0.152), between age and BAI was –0.038 (P = 0.037), and between BAIT and BDI-II 0.650 (P ≤ 0.001). Conclusions. The age group with the highest frequency of depression and anxiety was from 20 to 29 years. The absence of a stable partner represented an important risk factor for anxiety and depression during pregnancy.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Gurkiran Birdi ◽  
Richard Cooke ◽  
Rebecca Knibb

Background. Food allergy is related to poorer quality of life (QoL) and mental health of caregivers. Many parents diagnose food allergy in their child without seeking medical care and there is limited research on this group. This study investigated parental QoL and mental health in parents of children with parent-diagnosed food allergy (PA), medically diagnosed food allergy (MA), and a control group with no allergy (NA). Methods. One hundred and fifty parents from a general population completed validated measures of QoL, anxiety, depression, and stress. Results. Parents of children with food allergy (PA or MA) reported higher stress, anxiety, and depression than the control group (all p<0.05). Parents of children with MA reported poorer food allergy related QoL compared to parents of children with PA (p<0.05); parents of children with PA reported poorer general QoL compared to parents of children with MA (p<0.05). Conclusion. Parents of children with food allergy have significantly poorer mental health compared to healthy controls, irrespective of whether food allergy is medically diagnosed or not. It is important to encourage parents to have their child medically tested for food allergy and to recognise and refer for psychological support where needed.


Circulation ◽  
2017 ◽  
Vol 135 (suppl_1) ◽  
Author(s):  
Francisco E Ramirez ◽  
Neil Nedley

Objective: Plant-based nutrition, exercise, proper rest, relaxation techniques and other healthy behaviors can be beneficial to the cardiovascular system. We assess the impact that this healthy behaviors have before and after an 8-week educational community-based program. Participants and Methods: The program was developed by the Nedley Clinic in Ardmore, Oklahoma, USA. This medical clinic trained and certified lay and professional people around the world in 4 continents. The program does not create a doctor-patient relationship. Recruitment is done by, for example radio, TV, handouts, newspaper and word of mouth. Those who chose to participate met once a week for 8 weeks for a 2 hour program, it consisted of a 45 minute DVD presentation by a physician experienced in lifestyle interventions and a facilitated small group discussion together with weekly practical assignments. The program was available in Spanish and English. The Nedley Depression Recovery Program Assessment Test (registration TX 7-398-022) was used. It assessed depression level based on DSM-5 [The Diagnostic and Statistical Manual of Mental Disorders Volume 5] criteria, demographics, anxiety, emotional intelligence and patient history. The depression was classified into 4 categories as the DSM-5, as none (0-6), mild (7-10), moderate (11-19) or severe (20 or more). Participants that finished the program from 2007 to 2016 that were of geriatric age (55 years old and older at baseline) were included. Both depressed and non-depressed participated on the program. Results: From 5997 participants that finished the program n=2928 were geriatrics. Mean age 64.7 SD 7.2, n=2075 (70.8%) were females. Demographic were White 2598 (88.7%), Black 107 (3.6%), Hispanic 144 (4.9%) and other (2.8%). Participants were from Africa, Europe, Oceania and America. At baseline mean group depression was 11.2 (Moderate), SD 7.3. That group was composed of 960 (32.7%) with none depression, 474 (16.1%) with mild depression, 981 (33.5%) with moderate depression and 513 (17.5%) with severe depression. By the end of the 8-weeks mean depression was 6 (none), SD 5.7. That group was composed of 1854 (69.3%) with none depression, 476 (16.2%) with mild depression, 506 (17.2%) with moderate depression and 92 (3.1%) with severe depression. Conclusion: It seems that the intervention effectively improves mental health in this geriatric population with different levels of depression responding well to the program. This seems to be an effective way to apply community wide interventions to improve population-wide health. A control group and further follow up would be recommended.


2021 ◽  
Author(s):  
Penelope Smyth ◽  
Kaitlyn E Watson ◽  
Ross T. Tsuyuki

Abstract Background Canada has one of the highest rates of multiple sclerosis (MS) in the world. Treatments and supports for people with MS (PwMS) have become increasingly complex, requiring individualized and adaptive care. Specialized NPs provide advanced skills to those with complex medical conditions, with potential to enhance the health, functioning and quality of life for PwMS. This study aims to determine the effect of Nurse Practitioners (NPs) on depression and anxiety levels in PwMS. Methods We will perform a parallel randomized controlled trial. PwMS who are followed by general private-practice neurologists will be randomly assigned to the intervention group (NP-led care) or the ‘usual care’ control group (general neurologist or family physician and registered nurse support). In the intervention group, the NP will assess and provide care to the MS patient and their caregiver at a baseline visit, with 3-month and 6-month follow-up visits. PwMS in the control group will receive usual care provided by their community neurologists or family physicians with the standard assistance provided by registered nurses experienced in MS care. The primary outcome will be the difference in change in the patient’s anxiety and depression scores as measured by the validated Hospital Anxiety and Depression Scale (HADS) questionnaire at 3 months. Secondary outcomes will include difference in change in HADS at 6 months; Modified Fatigue Impact Scale scores (MSIF) at 3 and 6 months; EQ-5D scores at 3 and 6 months; caregiver health-related quality of life in MS measures (CAREQOL-MS) at 3 and 6 months; number of visits and phone calls to health-care professionals recorded by patient, and satisfaction with NP-led care vs usual care measured by the validated Consultant Satisfaction Questionnaire. Discussion Findings from this study will contribute to exploring benefits of advanced nursing practitioner interventions for PwMS followed by general neurologists and family physicians in a community setting. It will provide evidence of the benefits of NP-led care for PwMS and offer an alternative healthcare resource for management of MS. Trial Registration: Retrospectively registered June 26, 2020 at ClinicalTrials.gov (Unique protocol ID:Pro00069595);url: https://register.clinicaltrials.gov/prs/app/action/SelectProtocol?sid=S0009VEL&selectaction=Edit&uid=U00053N2&ts=4&cx=5oyfdk Protocol version: January 2017, version 1


2021 ◽  
Vol 5 (4) ◽  
pp. 163-166
Author(s):  
Changxin Dou

Objective: To explore the relationship between neuropathic headache, and depression and anxiety, as well as to adopt reasonable methods to reduce patients’ depression and anxiety. Methods: From June 2019 to May 2021, a total of 89 neuropathic headache patients were treated in our hospital, which is Yidu Central Hospital of Weifang and they were recorded as the observation group. During the same period, healthy individuals were randomly selected using a random number table method and 91 cases were randomly selected and recorded as the control group. Through the questionnaire survey and the use of SAS and SDS scores, the anxiety and depression of healthy people were evaluated, and the correlation between neurological headache, and anxiety and depression were analyzed. Results: In the control group, the number of people with mild, moderate, and severe anxiety were three, two, and zero, accounting for 3.30%, 2.20%, and 0.00%, respectively. The total anxiety was 5.50%, and the SAS score was 31.23 3.22; In the observation group, the number of people with mild, moderate, and severe anxiety were fourteen, eleven, and six, accounting for 15.73%, 12.36%, and 6.74%, respectively. The total anxiety was 34.83%, and the SAS score was 49.56 4.98, which was measured. The data shows that the control group is significantly lower than the observation group in terms of the number of people or the anxiety score, and both P<0.05 are statistically significant; the number of mild, moderate, and severe depression in the control group is four, two, and zero, respectively. They were 4.40%, 2.20%, 0.00%, the total depression was 6.60%, and the SAS score was 33.23 3.24; the number of people with mild, moderate, and severe depression in the observation group were sixteen, eleven, and five, respectively. 17.98%, 12.36%, 5.62%, total depression degree was 35.96%, SAS score was 46.56 4.68. The measurement data showed that the control group was significantly lower than the observation group in terms of the number of people or the depression score, and both were P<0.05, which was statistically significant. Conclusion: Patients with neuropathic pain are usually accompanied by anxiety and depression. Anxiety and depression are also important factors that affect patients with neuropathic pain. Psychotherapy intervention for patients is very necessary to relieve patients’ anxiety and depression. Thereby reducing the pain of the patient.


2020 ◽  
Author(s):  
BC Udaya Bahadur ◽  
Sunil Pokharel ◽  
Sabika Munikar ◽  
Chetan Nidhi Wagle ◽  
Pratik Adhikary ◽  
...  

AbstractBackgroundIn response to the COVID-19 pandemic, incoming travelers were quarantined at specific centers in Nepal and major checkpoints in Nepal-India border. Nepal adopted a generic public health approaches to control and quarantine returnee migrants, with little attention towards the quality of quarantine facilities and its aftermath, such as the poor mental health of the returnee migrants. The main objective of this study was to explore the status of anxiety and depression, and factors affecting them among returnee migrants living in institutional quarantine centers of western Nepal.MethodsA mixed method approach was used which included a quantitative survey and in-depth interviews (IDIs). Survey questionnaire utilized Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) tools, which were administered among 441 quarantined returnee migrants and IDIs were conducted among 12 participants which included a mix of quarantined migrants and healthcare workers from the quarantine centres. Descriptive and inferential analyses were conducted on quantitative data; and thematic analysis was utilized for qualitative data.ResultsMild depression (9.1%; 40/441) and anxiety (16.1%, 71/441) was common among respondents followed by moderate depression and anxiety {depression (3.4%; 15/441), anxiety (4.1%, 18/441)} and severe depression and anxiety {depression (1.1%; 5/441), anxiety (0.7%, 3/441)}. Anxiety and depression were independent of their socio-demographic characteristics. Perceived fear of contracting COVID-19, severity and death were prominent among the respondents.Respondents experienced stigma and discrimination in addition to being at the risk of disease and possible loss of employment and financial responsibilities. In addition, poor (quality and access to) health services, and poor living condition at the quarantine centres adversely affected respondents’ mental health.ConclusionDepression and anxiety among quarantined population warrants more research. Institutional quarantine centers of Karnali province of Nepal were in poor conditions which adversely impacted mental health of the respondents. Poor resources allocation for health, hygiene and living conditions can be counterproductive to the population quarantined.


PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254126
Author(s):  
Udaya Bahadur B. C. ◽  
Sunil Pokharel ◽  
Sabika Munikar ◽  
Chetan Nidhi Wagle ◽  
Pratik Adhikary ◽  
...  

Background In response to the COVID-19 pandemic, incoming travelers were quarantined at specific centers in Nepal and major checkpoints in Nepal-India border. Nepal adopted a generic public health approaches to control and quarantine returnee migrants, with little attention towards the quality of quarantine facilities and its aftermath, such as the poor mental health of the returnee migrants. The main objective of this study was to explore the status of anxiety and depression, and factors affecting them among returnee migrants living in institutional quarantine centers of western Nepal. Methods A mixed method approach in this study included a quantitative survey and in-depth interviews (IDIs) among respondents in quarantine centers of Karnali province between 21st April and 15th May 2020. Survey questionnaire utilized Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) tools, which were administered among 441 quarantined returnee migrants. IDIs were conducted among 12 participants which included a mix of six quarantined migrants and healthcare workers each from the quarantine centres. Descriptive and inferential analyses were conducted on quantitative data; and thematic analysis was utilized for qualitative data. Results Mild depression (9.1%; 40/441) and anxiety (16.1%; 71/441) was common among respondents followed by moderate depression and anxiety {depression (3.4%; 15/441), anxiety (4.1%; 18/441)} and severe depression and anxiety {depression (1.1%; 5/441), anxiety (0.7%; 3/441)}. Anxiety and depression were independent of their socio-demographic characteristics. Perceived fear of contracting COVID-19, severity and death were prominent among the respondents. Respondents experienced stigma and discrimination in addition to being at the risk of disease and possible loss of employment and financial responsibilities. In addition, poor (quality and access to) health services, and poor living condition at the quarantine centres adversely affected respondents’ mental health. Conclusion Depression and anxiety were high among quarantined population and warrants more research. Institutional quarantine centers of Karnali province of Nepal were in poor conditions which adversely impacted mental health of the respondents. Poor resource allocation for health, hygiene and living conditions can be counterproductive to the population quarantined.


2021 ◽  
Vol 11 (7) ◽  
pp. 926
Author(s):  
Ángel Rosa-Alcázar ◽  
José Luis Parada-Navas ◽  
María Dolores García-Hernández ◽  
Sergio Martínez-Murillo ◽  
Pablo J. Olivares-Olivares ◽  
...  

Background: The main aim was to examine changes in coping strategies, anxiety and depression in obsessive–compulsive and schizophrenia patients during COVID-19, in addition to controlling the influence of intolerance to uncertainty and experiential avoidance. Method: The first time, the study comprised (15–30 April 2020) 293 patients, 113 of whom were diagnosed with obsessive–compulsive disorder, 61 with schizophrenia and 119 healthy controls, aged 13–77 years (M = 37.89, SD = 12.65). The second time (15–30 November), the study comprised 195 participants (85 obsessive–compulsive patients, 42 schizophrenic patiens and 77 healthy controls participants). The evaluation was carried out through an online survey. Results: The clinical groups worsened over time in cognitive coping, anxiety and depression, while the control group only worsened in depression. Intergroup differences in anxiety, depression and coping strategies were maintained, highlighting the use of some maladaptive strategies (avoidance, spiritual) in clinical groups. Experiential avoidance and tolerance for uncertainty mainly affected coping. Conclusions: The duration of COVID-19 not only produced changes in anxiety and depression in clinical groups but also in coping strategies to face this pandemic and its consequences.


Sign in / Sign up

Export Citation Format

Share Document