scholarly journals PO-0108 Rotavirus Gastroenteritis Among Children Less Than 5 Years: A Cross Sectional Study On Demographic, Clinical, Laboratory And Treatment Profile

2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A285.1-A285
Author(s):  
J Cheriathu ◽  
L Jenny John ◽  
E Ignatius Dsouza ◽  
M Shamseldeen
Keyword(s):  
Clinical Laboratory ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Rotavirus Gastroenteritis ◽  
Treatment Profile

scholarly journals Correlation between lung infection severity and clinical laboratory indicators in patients with COVID-19: a cross-sectional study based on machine learning

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xingrui Wang ◽  
Qinglin Che ◽  
Xiaoxiao Ji ◽  
Xinyi Meng ◽  
Lang Zhang ◽  
...  
Keyword(s):  
Peripheral Blood Lymphocyte ◽  
Peripheral Blood ◽  
Blood Lymphocyte ◽  
Clinical Laboratory ◽  
Lung Infection ◽  
Cross Sectional Study ◽  
Ct Images ◽  
Sectional Study ◽  
Laboratory Examination ◽  
Cross Sectional

Abstract Background Coronavirus disease 2019 (COVID-19) has caused a global pandemic that has raised worldwide concern. This study aims to investigate the correlation between the extent of lung infection and relevant clinical laboratory testing indicators in COVID-19 and to analyse its underlying mechanism. Methods Chest high-resolution computer tomography (CT) images and laboratory examination data of 31 patients with COVID-19 were extracted, and the lesion areas in CT images were quantitatively segmented and calculated using a deep learning (DL) system. A cross-sectional study method was carried out to explore the differences among the proportions of lung lobe infection and to correlate the percentage of infection (POI) of the whole lung in all patients with clinical laboratory examination values. Results No significant difference in the proportion of infection was noted among various lung lobes (P > 0.05). The POI of total lung was negatively correlated with the peripheral blood lymphocyte percentage (L%) (r = − 0.633, P < 0.001) and lymphocyte (LY) count (r = − 0.555, P = 0.001) but positively correlated with the neutrophil percentage (N%) (r = 0.565, P = 0.001). Otherwise, the POI was not significantly correlated with the peripheral blood white blood cell (WBC) count, monocyte percentage (M%) or haemoglobin (HGB) content. In some patients, as the infection progressed, the L% and LY count decreased progressively accompanied by a continuous increase in the N%. Conclusions Lung lesions in COVID-19 patients are significantly correlated with the peripheral blood lymphocyte and neutrophil levels, both of which could serve as prognostic indicators that provide warning implications, and contribute to clinical interventions in patients.

Correlates of Axial Gout: A Cross-sectional Study

2012 ◽  
Vol 39 (7) ◽  
pp. 1445-1449 ◽  
Author(s):  
RUKMINI M. KONATALAPALLI ◽  
ELENA LUMEZANU ◽  
JAMES S. JELINEK ◽  
MARK D. MURPHEY ◽  
HONG WANG ◽  
...  
Keyword(s):  
Back Pain ◽  
Clinical Laboratory ◽  
Gouty Arthritis ◽  
Cross Sectional Study ◽  
Strongly Correlated ◽  
Sectional Study ◽  
Cross Sectional ◽  
American College Of Rheumatology ◽  
History Of ◽  
Hands And Feet

Objective.A cross-sectional study was undertaken to determine the prevalence of axial gout in patients with established gouty arthritis and to analyze clinical, laboratory, and radiological correlations.Methods.Forty-eight subjects with a history of gouty arthritis (American College of Rheumatology criteria) for ≥ 3 years under poor control were included. Subjects underwent history, physical examination, laboratory testing, and imaging studies, including radiographs of the hands and feet and computerized tomography (CT) of the cervical and lumbar spines and sacroiliac joints (SIJ). Patients with characteristic erosions and/or tophi in the spine or SIJ were considered to have axial or spinal gout.Results.Seventeen patients (35%) had CT evidence of spinal erosions and/or tophi, with tophi identified in 7 of the 48 subjects (15%). The spinal location of axial gout was cervical in 7 patients (15%), lumbar in 16 (94%), SIJ in 1 (6%), and more than 1 location in 14 (82%). Duration of gout, presence of back pain, and serum uric acid levels did not correlate with axial gout. Extremity radiographs characteristic of gouty arthropathy found in 21 patients (45%) were strongly correlated with CT evidence of axial gout (p < 0.001). All patients with tophi in the spine had abnormal hand or feet radiographs (p = 0.005).Conclusion.Axial gout may be a common feature of chronic gouty arthritis. The lack of correlation with back pain, the infrequent use of CT imaging in patients with back pain, and the lack of recognition of the problem of spinal involvement in gouty arthritis suggest that this diagnosis is often missed.

scholarly journals A hospital based cross sectional study on clinical, laboratory and complications profile of patients with hypertension

2021 ◽  
Vol 8 (11) ◽  
pp. 1724
Author(s):  
Keerthana Medidhi ◽  
Abhishek Sabbani
Keyword(s):  
Blood Pressure ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Kidney Disease ◽  
Blood Sugar ◽  
Clinical Laboratory ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Co Morbidity

Background: Hypertension is a major risk factor for critical diseases like coronary heart disease, stroke, kidney disease etc. Hence adequate control of blood pressure is of utmost importance to prevent these complications. Objectives of the study was to study the clinical, laboratory and complication profile of patients with hypertensionMethods: A hospital based cross sectional study was carried out among 30 known cases of hypertension. Investigations/measurements like Blood pressure, body mass index, lipid profile, fasting blood sugar were done for all cases.Results: Majority belonged to age group of >60 years (56.7%). Males were more (70%) than females (30%). About 60% had hypertension for >5 years. Only 26.7% were normal weight and remaining were either overweight or obese. The 56.7% admitted that they consumed alcohol. The 76.7% were non-smokers and only 10% were tobacco chewers. The 63.3% had family history of hypertension. Diabetes was the most common co morbidity associated with hypertension in 16.7% of the cases. The 10% each had coronary heart disease, and kidney disease. Mean levels of total cholesterol was 163.93; mean level of triglyceride was 159.53; mean level of HDL was 44.4; mean level of LDL was 84.76; mean level of Fasting blood sugar was 110.66; mean Systolic blood pressure was 134.66 and mean diastolic blood pressure was 86. Majority i.e., 90% were taking treatment for hypertension regularly while only 10% were not taking it regularly Conclusions: Hypertensives were elderly and males were more affected with hypertension than females. Majority were hypertensives for more than five years. Diabetes was the most common co morbidity. Blood pressure was under control as majority were taking treatment regularly

Clinical and Laboratory Correlates Of Depression among Kidney Disease Patients: A Cross-Sectional Study

2021 ◽  
Vol 6 (03) ◽  
pp. 192-196
Author(s):  
Mark S. Ezeme ◽  
Umezurike H. Okafor ◽  
Samuel O. Edeh
Keyword(s):  
Kidney Disease ◽  
Clinical Laboratory ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Appropriate Treatment ◽  
Treatment Of Depression ◽  
Spearman Correlation Test ◽  
Sociodemographic Profile ◽  
Predictors Of Depression

Background: Even though depression is one of the most common psychiatric disorders complicating physical illnesses, not many studies have elucidated the clinical and laboratory correlates and predictors of depression in patients with kidney disease. Method: Data was collected from 153 consented participants with chronic kidney disease (CKD) in a cross-sectional study using depression module of MINI International Neuropsychiatric Inventory (MINI). Clinical, laboratory and sociodemographic profile of each participant were obtained from patient`s folder. Analysis was done with descriptive statistics, Spearman correlation test and Logistic regression test. Result: Eight-nine (58.12%) participants were depressed; and depression positively correlated with one having being transfused blood; having received Erythropoietin (EPO), parenteral Iron; having being on Dialysis; Urea and Creatinine levels. Also found was negative correlation of depression with Packed Cell Volume (PCV) and Estimated Glomerular Filtration Rate (EGFR) levels. However, only the EGFR level and having being on dialysis were predictors of depression in CKD. Conclusion: Depression was highly prevalent among the participants, and clinicians should watch closely the above identified clinical and laboratory correlates and predictors so that early detection and appropriate treatment of depression in kidney disease patients may be enhanced.

scholarly journals Knowledge and Practices of Toxoplasmosis among Clinical Laboratory Professionals: A Cross-Sectional Study in Durango, Mexico

2017 ◽  
Vol 14 (11) ◽  
pp. 1413 ◽  
Author(s):  
Cosme Alvarado-Esquivel ◽  
Luis Sánchez-Anguiano ◽  
Luis Berumen-Segovia ◽  
Jesús Hernández-Tinoco ◽  
Yazmin Rico-Almochantaf ◽  
...  
Keyword(s):  
Clinical Laboratory ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals FACTORS ASSOCIATED WITH SEVERITY OF DISEASE IN PSORIATIC ARTHRITIS: A CROSS-SECTIONAL STUDY

2017 ◽  
Vol 26 (1) ◽  
pp. 24-29
Author(s):  
Tania Gudu ◽  
◽  
Alexandra Peltea ◽  
Andra Balanescu ◽  
Violeta Bojinca ◽  
...  
Keyword(s):  
Disease Severity ◽  
Clinical Laboratory ◽  
Cross Sectional Study ◽  
Severe Psoriasis ◽  
Sectional Study ◽  
Related Factors ◽  
Biologic Dmards ◽  
Cross Sectional ◽  
History Of ◽  
Laboratory Variables

Objectives. The objectives of this study were to evaluate the prevalence of disease severity in PsA and to assess the factors that might explain it. Methods. This was a cross-sectional study of unselected PsA patients. Severity was defined according to GRAPPA criteria of severity. Factors potentially associated with severity (demographical, clinical, laboratory variables, treatment related factors and comorbidities) were assessed by uni- and multivariate logistic regressions. Results. A total of 129 PsA patients were analysed: 77 (59.7%) women, mean±standard deviation age 53.5±11.8 years, and mean disease duration 7±7.4 years. Twenty-for patients (18.6%) had severe PsA. In the univariate regression, disease severity was associated with psoriasis duration, PsA duration, current moderate/severe skin disease, nail disease, history of corticotherapy, and total number of previous synthetic and biologic DMARDs. In the multivariate analysis, PsA severity was explained by the presence of current moderate/severe psoriasis – odds ratio 5.88 (95% confidence interval 1.39; 25.00) and history of corticosteroids – 4.65 (1.13; 18.87). Conclusion. PsA severity is best explained by the presence of moderate or severe psoriasis and past treatment with corticosteroids, but further longitudinal studies are needed to identify predictive factors.

scholarly journals Prevalence and Clinical Laboratory Features of Cryptosporidiosis in Children under 5 Years of Age: A Cross-Sectional Study of Hospital Cases of Acute Intestinal Infection

2018 ◽  
Vol 17 (4) ◽  
pp. 316-321
Author(s):  
Elena G. Starikova ◽  
Natalia I. Schubina ◽  
Olga V. Voronkova ◽  
Yulia V. Kovshirina ◽  
Nikolai D. Yarovoy
Keyword(s):  
Clinical Laboratory ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Blood Leukocytes ◽  
Cross Sectional ◽  
Intestinal Infections ◽  
Laboratory Features ◽  
Intestinal Pathogens ◽  
Blood Leukocyte ◽  
Children Under 5

Background. Cryptosporidium protozoa are the leading causative agent of diarrhea and cause of death in children under 5 years of age. The role of cryptosporidia in the development and course of acute intestinal infections (AII) in children in Russia remains unstudied. Objective. Our aim was to study the prevalence and clinical laboratory features of cryptosporidium-associated aII in children under 5 years of age. Methods. A cross-sectional study (conducted in March-June 2017) included children admitted to hospital with symptoms of AII (fever, loose watery stools, weakness, decreased appetite and/or vomiting) by the ambulance service. On admission, stool samples were collected from all patients. Cryptosporidium oocysts were determined by microscopic examination of faecal smears stained according to Tsil-Nielsen after preliminary concentration by a modified formalin-ether technique. The presence of intestinal pathogens was determined by a bacteriological technique and using a polymerase chain reaction. Results. The study included 107 children with AII (girls — 51%). Cryptosporidia were detected in 28 (26%) patients, in 93% of cases — together with bacterial and/or viral pathogens. The etiological structure of cryptosporidium-associated AII and AII in cryptosporidiosis negative children (n = 79) did not differ. On admission, children with cryptosporidium-associated AII had a higher blood leukocyte count — 13.0_109/L (9.2; 16.0) versus 8.3_109/L (6.1; 11.2) in children without cryptosporidiosis (p < 0.001). It has been also found that antibiotics were more often used in the treatment of children with cryptosporidium-associated AII — in 21 (75%) versus 39 (49%) in the comparison group (p = 0.026). Conclusion. Cryptosporidia are detected in every fourth child with AII under 5 years of age. Patients with cryptosporidia are distinguished by a higher level of blood leukocytes upon admission and a more frequent prescription of antibiotics than in the group of cryptosporidiosis negative patients.

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