scholarly journals Developing a classification system for haemoglobin management in patients with end-stage renal disease on haemodialysis: a secondary data analysis

BMJ Open ◽  
2017 ◽  
Vol 7 (11) ◽  
pp. e017423
Author(s):  
Tibor Kesztyüs ◽  
Ulrich Simonsmeier ◽  
Dorothea Kesztyüs

BackgroundOngoing discussion on anaemia management and target haemoglobin (Hb) levels in patients on haemodialysis with erythropoietin treatment require a systematic approach in evaluating current practice. Aim of the present study was to develop a new classification system to easily monitor Hb trajectories and categorise patients on haemodialysis.MethodsRoutine data from five dialysis centres in the USA collected between 2010 and 2016. Data were anonymised and only those from patients with fortnightly Hb values were included in the analysis. Entries on blood parameters and medication were standardised to achieve overall comparability. Data from each patient was grouped in periods of 120 days. Hb values above or below the target level of 10–12 g/dL were counted for each period. Periods were then assigned to Hb-classes according to the number of Hb values out of range per period: Hb-class I with 0–2, Hb-class II for 3–5 and Hb-class III for ≥6 values out of range.ResultsRecords from 3349 patients with fortnightly Hb values, information on haemodialysis data, laboratory parameters correlated to red blood cells and data on medication with erythropoiesis-stimulating agents (ESAs) were available. Patients were 64.4±15.9 years old; 55.0% were men. Statistical analysis revealed significant differences between Hb-classes in all of the examined parameters, except erythrocytes mean corpuscular volume and C reactive protein above the threshold, with more critical values in higher Hb-classes. The usage of ESAs showed a mean difference between Hb-class III and Hb-class I of 6.4 units/day and kilogram body weight in a 120-day period.ConclusionOur classification system allows an easily achievable overview of the patients’ responsiveness and performance of Hb management. Integrated into a disease management programme or continuous quality improvement, the classification delivers an instant appraisal without complex statistical or mathematical processing.

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1488-1493
Author(s):  
Jembulingam Sabarathinam ◽  
Revathi Duraisamy ◽  
Madhulaxmi M

Edentulism is the state of being edentulous without natural teeth in the oral cavity. Edentulism leads to impairment of normal function, aesthetics, Comfort and speech which is followed by sequelae of undesirable events which includes occlusal discrepancies, migration and spacing of surrounding teeth, loss of space, supra eruption of teeth and temporomandibular disorders. The Variation in the number and location of the edentulous spaces and its complex relation to the remaining tooth structure or the natural teeth constrains the need to classify the partial edentulous arches. The aim of the current study was to assess the frequency of partial edentulism according to Kennedy's classification system. The retrospective study was conducted among the outpatient department of Saveetha Dental College and Hospital from June 2019- august 2019. The patient data was assessed. The data were tabulated using MS-Excel. The data was then analysed using IBM SPSS software (version 20). Pearson's chi-square test was done. Male predilection (62%) was identified in relation to partial edentulism. The most frequently observed edentulism in maxillary and mandibular arch was Kennedy's class III (23% and 21% respectively). While Kennedy class I and II were observed in patients aged between 50-80 years (11% and 14% respectively), whereas Kennedy's class IV was majorly observed among patients aged between 20-30 years (5%) (p<0.05). There was an increased frequency of Kennedy’s class I and II pattern and a decline in Kennedy’s class III and IV with increase in age.


2020 ◽  
Vol 10 (2) ◽  
pp. 14-17
Author(s):  
Md Golam Rubby ◽  
Nihar Sultana ◽  
Fatema Jannath ◽  
Gazi Shamim Hassan

Background: Malocclusion is one of the most common dental problems together with dental caries, gingival disease, dental fluorosis which varies in different part of the world among different populations. The aim of this study was to assess the malocclusion pattern in Bangladeshi population to provide quantitative information regarding the pattern of dentofacial characteristics. Methods : This cross sectional study was carried out with the orthodontic records of 256 patients who attended and treated in the Department of Orthodontics ,Bangabandhu Sheikh Mujib Medical University (BSMMU) Hospital , Dhaka. Malocclusion pattern mainly assessed by Angle’s classification system; along with incisor classification system other variables like overjet, overbite, cross bite ,crowding, spacing and median diastema were recorded. Finally data were analyzed by using SPSS software (Version 21). Results : The study result showed out of 256 orthodontic patients majority (68.7%) were female, in Angle’s classification Class I malocclusion was the most prevalent (55.5%) type of malocclusion followed by Class II (38.3%) and Class III (6.3%). The most prevalent malocclusion trait found crowding (67.7%), followed by increase overjet (65.6%), increase overbite or deep bite (50.4%); the least prevalent malocclusion trait found scissor bite (1.2%) followed by posterior cross bite (5.1%) and median diastema (12.5%). Statistical significant relationship observed in the distribution of malocclusion by Angle’s classification with sex ( as p value < .05). Conclusion: This hospital based study concludes that in Angle’s classification system: Class I malocclusion was prevalent along with the malocclusion trait crowding, which actually gives a general idea about the malocclusion pattern in Bangladeshi population. Update Dent. Coll. j: 2020; 10 (2): 14-17


2017 ◽  
Vol 43 (5) ◽  
pp. 405-409
Author(s):  
Periklis Proussaefs ◽  
Abdulaziz AlHelal ◽  
Abdulrahman Taleb ◽  
Mathew T. Kattadiyil

There is controversy in the literature regarding the indicated retentive mechanism for implant-supported crowns. When adjacent implants are restored, the restoration can be screw retained, cement retained, or a combination of cement and screw retained. Adjacent implant-supported crowns can be restored as individual implant supported crowns or can be splinted. A classification system is proposed when adjacent implants are restored. The classification system describes currently available options to restore adjacent implants. Six types of prosthetic design options are proposed as Class I through Class VI. In Class I design, individual cement-retained crowns are made. In Class II, individual screw-retained crowns are fabricated. Class III involves fabrication of individual screw-retrievable/cement-retained crowns. Class IV prosthetic design involves splinted cement-retained implant crowns. Class V prosthetic design involves splinted screw-retained crowns, and Class VI involves splinted screw-retrievable/cement-retained implant supported crowns.


2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Rasmansyah Rasmansyah ◽  
M Zainal Aripin

<em>This research was conducted based on the existence of problems in the competence and physical work environment of employee performance. This study aims to determine the effect of competencies and physical work environment simultaneously or partially on the performance of employees of PT. Suzuki Indomobil Motor. The sampling technique is the sample random sampling technique. The type of research used is descriptive and verivative research methods, with data collection techniques using primary data and secondary data. The results showed that competency, physical work environment, and performance were categorized quite well. Based on the calculation, it can be seen that simultaneously the competence and physical work environment have a positive and significant influence on the performance of the employees of PT. Suzuki Indomobil Motor. Partially shows that the physical work environment has the most dominant influence on the performance of employees of PT. Suzuki Indomobil Motor</em>


1995 ◽  
Vol 60 (9) ◽  
pp. 1502-1528 ◽  
Author(s):  
Oldřich Pytela

Alternative interpretation of substituent effects (AISE) starts from the presumption that a substituent only possesses a single property described by a single substituent constant. This property is transmitted to the reaction centre by three different ways depending on the interaction type in the triad reaction centre - basic skeleton - substituent. For interpretation it is substantial whether or not the substituent has p electrons at the atom adjacent to the basic skeleton. If it has none, the substituent belongs to class I and operates only by its basic effect described by the mentioned single substituent constant. Substituents of class II possess a free electron pair at the atom adjacent to the basic skeleton, and those of class III have a multiple bond between the first and the second atoms which is polarized in the direction from the basic skeleton. Substituent effects in class I are described by a substituent constant identical with σI constant. Substituents in classes II and III show additional effects proportional to the same constant. Hence, a separate treatment of substituent effects in the individual classes provides three straight lines intersecting in a common point. Mathematically, the description of substituent effects in this approach is expressed by a family of lines with a single explaining variable. The point of intersection, which is referred to as the iso-effect point, is not identical with the classic standard substituent - hydrogen - but is near to CN substituent. The approach given has the advantage of adopting a single substituent constant whose scale can be adjusted relatively precisely. Its drawback (like in the case of the correlation equations derived from the principle of separation of substituent effects) lies in a more extensive set of substituents needed for a correlation. The AISE principle has been applied to 318 series of experimental data describing effects of 32 substituents in a large variety of chemical models (aliphatic, alicyclic, aromatic, heteroaromatic, with or without direct conjugation between reaction centre and substituent) in both chemical reactions and equilibria. A comparison with two other correlation relations with two and three substituent constants for interpretation of substituent effects based on the principle of separation of the individual substituent effects showed that the closeness of AISE based correlations is comparable with that of the correlation equations currently used. It was somewhat less successful in the models with direct conjugation between reaction centre and substituent but the AISE principle can be used even in these cases.


2020 ◽  
pp. 097674792096686
Author(s):  
Yudhvir Singh ◽  
Ram Milan

Public sector banks have been merged by the government in the last few years. This is the rationale behind conducting this study. The purpose of this article is to determine the factors affecting the performance of public sector banks in India and the interrelationship between bank-specific determinants and performance of public sector banks. In this article, we shall analyse the financial data of all the public sector commercial banks for a period spread across 11 years (2009–2019); Capital adequacy, Assets quality, Management efficiency, Earning, and Liquidity (CAMEL) has been used as a performance determinant; system generalised method of moments (GMM) analysis has been used to find the effect of determinants on the performance measurement of public sector banks; and CCA (canonical correlation analysis) has been used to find the interrelationship between the bank-specific determinants and the performance of public sector banks. The finding has important implications in terms of performance in the banking sector. Certain limitations of this study are: It is based on secondary data. The study only covers the financial aspects and not the non-financial aspects. It is found that the asset quality is negatively related with performance of public sector banks. Liquidity and inflation are inversely related to performance of public sector banks in India. Capital adequacy is positively related with banks’ performance, but inversely related with banks’ interest margin. GDP growth has a significant positive impact on banks’ performance, but inversely related with banks’ interest income. Inflation rate is inversely related with banks’ performance. Banking sector reforms are insignificantly related with banks’ performance.


Healthcare ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 413
Author(s):  
Hui-Ling Chen ◽  
Jason Chen-Chieh Fang ◽  
Chia-Jung Chang ◽  
Ti-Feng Wu ◽  
I-Kuan Wang ◽  
...  

Background. Previous studies have shown that environmental cadmium exposure could disrupt salivary gland function and is associated with dental caries and reduced bone density. Therefore, this cross-sectional study attempted to determine whether tooth decay with tooth loss following cadmium exposure is associated with some dental or skeletal traits such as malocclusions, sagittal skeletal pattern, and tooth decay. Methods. Between August 2019 and June 2020, 60 orthodontic patients with no history of previous orthodontics, functional appliances, or surgical treatment were examined. The patients were stratified into two groups according to their urine cadmium concentrations: high (>1.06 µg/g creatinine, n = 28) or low (<1.06 µg/g creatinine, n = 32). Results. The patients were 25.07 ± 4.33 years old, and most were female (female/male: 51/9 or 85%). The skeletal relationship was mainly Class I (48.3%), followed by Class II (35.0%) and Class III (16.7%). Class I molar relationships were found in 46.7% of these patients, Class II molar relationships were found in 15%, and Class III molar relationships were found in 38.3%. The mean decayed, missing, and filled surface (DMFS) score was 8.05 ± 5.54, including 2.03 ± 3.11 for the decayed index, 0.58 ± 1.17 for the missing index, and 5.52 ± 3.92 for the filled index. The mean index of complexity outcome and need (ICON) score was 53.35 ± 9.01. The facial patterns of these patients were within the average low margin (26.65 ± 5.53 for Frankfort–mandibular plane angle (FMA)). There were no significant differences in the above-mentioned dental indices between patients with high urine cadmium concentrations and those with low urine cadmium concentrations. Patients were further stratified into low (<27, n = 34), average (27–34, n = 23), and high (>34, n = 3) FMA groups. There were no statistically significant differences in the urine cadmium concentration among the three groups. Nevertheless, a marginally significant p-value of 0.05 for urine cadmium concentration was noted between patients with low FMA and patients with high FMA. Conclusion. This analysis found no association between environmental cadmium exposure and dental indices in our orthodontic patients.


Author(s):  
Afef Hfaiedh ◽  
Ahmed Chemori ◽  
Afef Abdelkrim

In this paper, the control problem of a class I of underactuated mechanical systems (UMSs) is addressed. The considered class includes nonlinear UMSs with two degrees of freedom and one control input. Firstly, we propose the design of a robust integral of the sign of the error (RISE) control law, adequate for this special class. Based on a change of coordinates, the dynamics is transformed into a strict-feedback (SF) form. A Lyapunov-based technique is then employed to prove the asymptotic stability of the resulting closed-loop system. Numerical simulation results show the robustness and performance of the original RISE toward parametric uncertainties and disturbance rejection. A comparative study with a conventional sliding mode control reveals a significant robustness improvement with the proposed original RISE controller. However, in real-time experiments, the amplification of the measurement noise is a major problem. It has an impact on the behaviour of the motor and reduces the performance of the system. To deal with this issue, we propose to estimate the velocity using the robust Levant differentiator instead of the numerical derivative. Real-time experiments were performed on the testbed of the inertia wheel inverted pendulum to demonstrate the relevance of the proposed observer-based RISE control scheme. The obtained real-time experimental results and the obtained evaluation indices show clearly a better performance of the proposed observer-based RISE approach compared to the sliding mode and the original RISE controllers.


Author(s):  
Godfred O Antwi ◽  
Darson L Rhodes

Abstract Background Concern about the health impacts of e-cigarette use is growing; however, limited research exists regarding potential long-term health effects of this behavior. This study explored the relationship between e-cigarette use and COPD in a sample of US adults. Methods A secondary data analysis using data from the 2018 Behavioral Risk Factor Surveillance Survey in the USA was computed to examine associations between e-cigarette use and COPD controlling for conventional cigarette smoking status, past month leisure physical activity and demographic characteristics including age, sex, education, race, marital status and body mass index. Results Significant associations between e-cigarette use and COPD among former combustible cigarette smokers and those who reported never using combustible cigarettes were found. Compared with never e-cigarette users, the odds of having COPD were significantly greater for daily e-cigarette users (OR = 1.53; 95% CI: 1.11–2.03), occasional users (OR = 1.43, 95% CI: 1.13–1.80) and former users (OR = 1.46 95% CI: 1.28–1.67). Conclusions Findings from this study indicate a potential link between e-cigarette use and COPD. Further research to explore the potential effects of e-cigarette on COPD is recommended.


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