scholarly journals Thyroid dysfunction and electrocardiographic changes in subjects without arrhythmias: a cross-sectional study of primary healthcare subjects from Copenhagen

BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e023854 ◽  
Author(s):  
Bhupendar Tayal ◽  
Claus Graff ◽  
Christian Selmer ◽  
Kristian Hay Kragholm ◽  
Magnus Kihlstrom ◽  
...  

ObjectiveThe objective of the present study was to investigate associations of both overt and subclinical thyroid dysfunction with common ECG parameters in a large primary healthcare population.DesignCross-sectional study.Setting and participantsThe study population comprised of primary healthcare patients in Copenhagen, Denmark, who had a thyroid function test and an ECG recorded within 7 days of each other between 2001 and 2011.Data sourcesThe Danish National Patient Registry was used to collect information regarding baseline characteristics and important comorbidities.Outcome measure and study groupsCommon ECG parameters were determined using Marquette 12SL software and were compared between the study groups. The study population was divided into five groups based on their thyroid status. Euthyroid subjects served as the reference group in all analyses.ResultsA total of 132 707 patients (age 52±17 years; 50% female) were included. Hyperthyroidism was significantly associated with higher heart rate and prolonged QTc interval with significant interaction with age (p<0.009) and sex (p<0.001). These associations were less pronounced for patients with higher age. Subclinical hyperthyroidism was associated with higher heart rate among females, and a similar trend was observed among males. Hypothyroidism was associated with slower heart rate and shorter QTc but only in women. Moreover, longer P-wave duration, longer PR interval and low voltage were observed in patients with both subclinical and overt hypothyroidism. However, the presence of low voltage was less pronounced with higher age (p=0.001).ConclusionBoth overt and subclinical thyroid disorders were associated with significant changes in important ECG parameters. Age and gender have significant impact on the association of thyroid dysfunction particularly on heart rate and QTc interval.

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Sanaa Ait Hamou ◽  
Brahim Lamhamdi ◽  
Ichraq Hayah ◽  
Imane Belbacha ◽  
Abderrahim Sadak ◽  
...  

The aim of this descriptive cross-sectional study is to evaluate the knowledge of toxoplasmosis among medical, biology, and veterinary students in Rabat in Morocco. The data was collected by using a questionnaire which includes demographic characteristics, epidemiology, diagnosis, and clinical issues related to knowledge of toxoplasmosis. During analysis, the study groups were divided based upon their specialty of students who were medical, biology, and veterinary students. Out of 230 students, 55.2% were female and 44.8% were male. The average age of the study population is 21.7 ± 02 years. Less than half (42.6%) have heard of the disease; most of them have heard from faculty during studies in classrooms with 75.8%, and 3.2% were from the internet. Only 36.5% knew the correct causative agent of toxoplasmosis, and 32.1% were aware of the definitive host. The current study documented that there are gaps in the knowledge of the students regarding toxoplasmosis. Therefore, the present study puts the basis for future studies highlighting the importance of educating students to improve knowledge and attitudes towards toxoplasmosis.


2017 ◽  
Vol 56 (6) ◽  
pp. 325
Author(s):  
Surya Jayanti Kadek ◽  
Dewi Kumara Wati Ketut ◽  
Karyana Putu Gede

Background About 60% of individuals with atopic dermatitis (AD) develop their first manifestation during infancy. Cow’s milk (CM) exposure is considered to be a risk factor for AD.Objective To evaluate for an association between cow’s milk exposure and atopic dermatitis in infants > 6 months of age.  Methods This cross-sectional study consisted of subjects from a previous study and new subjects recruited in order to meet the minimum required number of subjects. Our study population comprised 120 infants, born between 1 February and 30 November, 2012 in Sanglah Hospital, Denpasar. Subjects were divided into CM and non-CM groups and analyzed for their risk of AD. Subjects were included to CM group if they were fed with cow’s milk/formula  and included to non-CM group if they were breastfeed exclusively in the first six months of life. Other possible risk factors were assessed by multivariate analysis. Results One hundred twenty subjects were enrolled and analyzed (59 in the CM and 61 in the non-CM groups). The prevalence of AD was 30%. Multiple logistic regression analysis revealed a significant association between CM exposure and AD, with odds ratio (OR) 2.37 (95%CI 1.036 to 5.420; P=0.04). In addition, maternal diet including eggs and/or cow’s milk during the breastfeeding period was significantly associated with AD in infants (OR 3.18; 95%CI 1.073 to 9.427; P=0.04).Conclusion Cow’s milk exposure is significantly associated with atopic dermatitis in infants  > six months of age. 


2014 ◽  
Vol 37 (8) ◽  
pp. 779-784 ◽  
Author(s):  
Hiromi Mori ◽  
Isao Saito ◽  
Eri Eguchi ◽  
Koutatsu Maruyama ◽  
Tadahiro Kato ◽  
...  

Author(s):  
Anupama Pulla ◽  
Asma . ◽  
Nanduri Samyuktha ◽  
Soumya Kasubagula ◽  
Aishwarya Kataih ◽  
...  

Background: Computer vision syndrome is a complex of eye and vision problems related to near work which are experienced due to prolonged computer use. Computers demand near work, for longer duration which increases discomfort of eye and prolonged exposure to the discomfort leads to a cascade of symptoms that can be referred as computer vision syndrome. The aims and objectives of the study were to determine the prevalence of computer vision syndrome among engineering students of Hyderabad, Telangana and to determine the factors related to computer vision syndrome among study population.Methods: A cross sectional study was carried out from March to June 2017 among students of an engineering college in Hyderabad, Telangana. A convenient sample of 300 students was taken and a predesigned, pre tested questionnaire was used to obtain information.Results: Majority of study population were males (56.3%). Around 75.1% of study population were using all the electronic gadgets like computers, laptops and smartphones. The prevalence of computer vision syndrome was found to be 60.3%. Around 46.7% of study population viewed the screen from a distance of 22-40 centimeters.Conclusions: As students pursuing engineering stream are the future IT and Computer software engineers, preventive strategies adopted by them will significantly decrease the burden of computer vision syndrome and improve productivity. In this study a significant proportion of the engineering students were found to be having vision problems, which emphasizes the need to adopt preventive measures to avoid computer vision syndrome. 


2020 ◽  
Author(s):  
Rehab A. Rayan

For improving accomplished attempts to stop smoking, it is necessary to learn about the qualities of individuals who can willingly stop smoking. This study seeks to discover the willingness degree and associated determinants to stop smoking between adult visitors of a primary healthcare centre in an urban area of Alexandria in Egypt. In this single point and descriptive cross-sectional study, a semi-structured questionnaire was distributed to a sample of 53 adults aged ≥18 years in May 2019. Descriptive statistical analyses were conducted to evaluate the determinants influencing the willingness to stop smoking. Of the 53 respondents (with a mean age of 38.7 years old), 41.5% of them were males. Almost 18.9% of the respondents were ongoing smokers (36.4% of males and 6.5% of females), though 83.7% of those smokers were willing to stop smoking. The number of male smokers was significantly greater than female smokers (Pearson Chi-Square = 7.52, p-value = 0.006). Determinants, which can favourably influence the willingness to stop smoking, were believing that smoking is a health risk to them (100%) and the others around (94.3%). A bulk of participants (56.6%) doubted the need for nicotine supplements to help in smoking cessation. Smoker respondents were willing to stop smoking. Understanding that smoking is a health hazard for both smokers and the others around can motivate smoking cessation. Relying on nicotine supplements alone might not add favourably to a strong smoking cessation decision. Tailoring campaigns to raise awareness about smoking health hazards’ would support and sustain smoking cessation.


2021 ◽  
Vol 8 (5) ◽  
pp. 183-186
Author(s):  
Channanayaka Chandrashekhar ◽  
Manovihari Vuyyuru ◽  
Prajwala Hassan Vasudev ◽  
George Mathew Panachiyil ◽  
Tirin Babu

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