Factors associated with HPV and other self-reported STI coinfections among sexually active Brazilian young adults: cross-sectional nationwide study

ObjectivesTo analyse factors associated with genital human papillomavirus (HPV) and other self-reported sexually transmitted infection (STI) coinfections among women and men aged 16–25 years from Brazil.DesignA cross-sectional, nationwide, multicentre study.Setting119 primary healthcare centres between September 2016 and November 2017.Participants6388 sexually active young adults were enrolled by trained health professionals.Primary outcome measureGenital HPV and other self-reported STI coinfections.ResultsOf 3512 participants with valid data for genital HPV and (STI)-positive status, 276 (9.60%, 95% CI 7.82% to 11.36%) had HPV/STI coinfection. Among men, HPV/STI coinfection was more prevalent than HPV infection alone. Among HPV-positive participants, the percentage of subjects who reported having another STI was highest for gonorrhoea at 4.24% (95% CI 2.67% to 5.81%), followed by syphilis, herpes and HIV. Smoking, drug use and ever having a same-sex sexual experience were risk factors that were uniquely associated with HPV/STI coinfection compared with HPV infection alone.ConclusionsThe results identified a low prevalence of self-reported STIs, but in participants with at least one STI, the prevalence of HPV was high. These results reinforce the importance of implementing strategies to prevent risky behaviours among Brazilian young adults.

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Prevalence of High Risk HPV in HIV-Infected Women From Belém, Pará, Amazon Region of Brazil: A Cross-Sectional Study

Frontiers in Public Health ◽

10.3389/fpubh.2021.649152 ◽

2021 ◽

Vol 9 ◽

Author(s):

Jacqueline Cortinhas Monteiro ◽

Ricardo Roberto de Souza Fonseca ◽

Tuane Carolina de Sousa Ferreira ◽

Luana Lorena Silva Rodrigues ◽

Andreza Reis Brasil da Silva ◽

...

Keyword(s):

Cervical Cancer ◽

High Risk ◽

Hpv Infection ◽

Cross Sectional Study ◽

Reproductive Age ◽

Transmitted Infection ◽

Cross Sectional ◽

Multiple Sexual Partners ◽

Sexually Transmitted ◽

High Risk Hpv

Human papillomavirus (HPV) is the most common sexually transmitted infection in the world. Several studies have shown a higher prevalence of HPV infection in HIV-infected women. The aim of this study was to determine the prevalence and the genotype diversity of HPV infection in HIV-infected women. From April 2010 to December 2012 cervical specimens were collected from 169 HIV-infected women who screening for cervical cancer at Reference Unit in Belém. The detection of HPV infection was performed by nested PCR and HPV type was performed using a commercial system. The prevalence of HPV infection was 63.3%. Of the 47 genotyped samples, 40.4% was found positive for high risk-HPV 16 and 12.8% for high risk-HPV 52. HPV infection was predominant in the group of women with no incidence of cytological abnormalities and more prevalent in women of reproductive age, unmarried, low education level, and who reported use condoms during sexual intercourse. It was observed an association between HPV infection and independent variables, such as condom use, multiple sexual partners, and history of sexually transmitted diseases. High-risk types of HPV infection were prevalent in our study. Infection with multiple high-risk HPV genotypes may potentiate the development of cervical cancer in HIV-infected women.

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Prevalence of Chlamydia trachomatis in a public colposcopy clinic population

Sexual Health ◽

10.1071/sh06050 ◽

2007 ◽

Vol 4 (2) ◽

pp. 133 ◽

Cited By ~ 3

Author(s):

Rodney W. Petersen ◽

Sepehr N. Tabrizi ◽

Suzanne Garland ◽

Julie A. Quinlivan

Keyword(s):

Chlamydia Trachomatis ◽

Chlamydial Infection ◽

Transmitted Disease ◽

Hpv Infection ◽

Public Health Issue ◽

Transmitted Infection ◽

Cross Sectional ◽

Sexually Transmitted ◽

Clinic Population ◽

Colposcopy Clinic

Background: Chlamydia trachomatis is a major public health issue, with notifications of this sexually transmitted disease continuing to rise in Australia. Women attending colposcopy clinics are referred for treatment of cervical abnormalities often associated with human papilloma virus (HPV) infection. There is evidence that women who have acquired one sexually transmitted infection, such as HPV, are at higher risk of acquiring another. Women attending colposcopy clinics may therefore be at risk of undiagnosed infection with C. trachomatis. Aim: To determine the prevalence of C. trachomatis in women attending a public metropolitan colposcopy clinic in Victoria. Methods: A cross-sectional study was performed. Institutional ethics committee approval and informed consent were obtained. Consecutive women attending the colposcopy clinic completed a questionnaire and had a swab collected from the endocervix for analysis by polymerase chain reaction for C. trachomatis. Positive screens were treated in accordance with best practice. Data were analysed with Minitab Version 2004 (Minitab Inc, State College, PA, USA). Results: Of 581 women approached to participate in the trial, consent was obtained from 568 women (98%) and final outcome data was available on 560 women (99%). The overall rate of chlamydial infection was 2.1% (95% CI 1.5–2.7%). However, in women aged 25 years or less the rate was 5.8% (95% CI 3.8–7.8%) and in women over 25 years it was only 0.9% (95% CI 0.4–1.4%). Apart from age, no other demographic factor was significantly associated with chlamydial infection. Conclusion: Although the prevalence of chlamydial infection in the colposcopy clinic population as a whole does not warrant a policy for routine screening, screening directed at women aged 25 years or less would gain the greatest yields in terms of cost efficacy. Such a policy should be implemented as standard practice.

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Knowledge and Health Beliefs of Nursing Students Toward Human Papilloma Virus and Vaccine Use

Asian Pacific Journal of Cancer Care ◽

10.31557/apjcc.2019.4.2.27-32 ◽

2019 ◽

Vol 4 (2) ◽

pp. 27-32

Author(s):

Fatjona Kamberi ◽

Eva Muhaj

Keyword(s):

Nursing Students ◽

Human Papilloma Virus ◽

Health Beliefs ◽

Perceived Risk ◽

Hpv Infection ◽

Statistical Association ◽

Transmitted Infection ◽

Cross Sectional ◽

Papilloma Virus ◽

Sexually Transmitted

Objective: Human Papilloma Virus (HPV) infection is the most common sexually transmitted among young people of both sexes. It is also the main cause of cervical cancer. This study aimed at assessing students’ knowledge and health beliefs about HPV infection and the use of the vaccine.Methods: The sample of the cross-sectional study was 120 randomly selected nursing students from the Faculty of Public Health, University of Vlore “Ismail Qemali” Albania. Anonymous, self-administered questionnaire based on the literature and Health Belief Model, was used for data collection in May 2017. The questionnaire included assessment questions for students’ knowledge and health beliefs about HPV and vaccine use. Also, questions about socio-demographic characteristics were included. Data analysis included the calculation of averages, frequencies, and confidence intervals. P values ≤0.05 were accepted as statistically significant.Result: Mean age 20.3±2.2 years, 92.44 % of students were female. 65.83% of students know that HPV is a sexually transmitted infection and a vaccine is available to prevent it. Ambiguities and uncertainties exist in regard to screening with Pap test after vaccination. Perceived benefits are high for 50.83% of students. Perceived severity appeared low as only 25% of students agree that they may be affected by HPV. Statistical association, p =0.0347 was found between perceived risk and the year of study. The parents’ role in vaccination against HPV have a strong statistical association, p=0.0058 with the year of study as only 8.33 % of students in the third year agree with the fact that that parents do not allow them to be vaccinated against HPV. Conclusion: The study noted the student’s ambiguity and misconceptions about HPV infection. Low severity and lack of knowledge about the vaccine emphasizes that identifying their current level of knowledge and the main source of information are essential to provide comprehensive and appropriate health education.

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Sexually transmitted infection diagnoses, sexualised drug use and associations with pre-exposure prophylaxis use among men who have sex with men in the UK

International Journal of STD & AIDS ◽

10.1177/0956462419897222 ◽

2020 ◽

Vol 31 (3) ◽

pp. 254-263

Author(s):

Matthew P Hibbert ◽

Caroline E Brett ◽

Lorna A Porcellato ◽

Vivian D Hope

Keyword(s):

Drug Use ◽

Sexually Transmitted Infection ◽

Transmitted Infection ◽

Cross Sectional ◽

Sexually Transmitted ◽

Factors Associated ◽

Hiv Test ◽

Condomless Anal Intercourse ◽

Sex With Men ◽

Exposure Prophylaxis

Previous research has focused on acceptability of pre-exposure prophylaxis (PrEP) use, but few community-based studies have been conducted regarding actual use, and PrEP use in the context of sexualised drug use remains understudied. A national online cross-sectional study recruited men who have sex with men (MSM) via social media (April–June 2018). Multivariable logistic regression was used to investigate factors associated with PrEP use. Bivariate analyses compared engaging in condomless anal intercourse (CAI) under the influence of specific drugs and recent sexually transmitted infection (STI) diagnoses (past 12 months) between MSM taking PrEP and those not. Overall, 6% (99/1581) MSM reported current PrEP use. Factors associated with PrEP use were increasing age, recent genitourinary medicine (GUM) attendance (95% versus 45%, aOR = 6.25, 95%CI 2.05, 19.03), an HIV test in the past three months (89% versus 23%, aOR = 14.22, 95%CI 6.76, 29.90), and recent engagement in chemsex (21% versus 4%, aOR = 3.56, 95%CI 1.78, 7.11). MSM taking PrEP were more likely to have had an STI diagnosis (42% versus 8%), most commonly chlamydia (26% versus 3%) and gonorrhoea (25% versus 4%). Considering the elevated levels of self-reported STI diagnoses among those on PrEP, there was a high level of engagement with sexual health services, which may help reduce onward STI transmission.

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Sex differences in the prevalence and determinants of HPV-related external genital lesions in young adults: a national cross-sectional survey in Brazil

BMC Infectious Diseases ◽

10.1186/s12879-020-05376-x ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Juliana Comerlato ◽

Natália Luiza Kops ◽

Marina Bessel ◽

Jaqueline Driemeyer Horvath ◽

Bruna Vieira Fernandes ◽

...

Keyword(s):

Young Adults ◽

Sex Differences ◽

Smoking Status ◽

Hpv Infection ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Sexually Transmitted ◽

Primary Health ◽

Hpv Types ◽

Male Sex

Abstract Background External genital lesions (EGL) are the most common sexually transmitted infections (STIs). We aimed to evaluate the prevalence, determinants and sex differences in EGL among young adults from Brazil. Methods Overall, 7694 participants (aged 16 to 25 years) underwent an interview, genital examination and sampling for HPV genotyping. Results The prevalence of EGL was 4.08% (234) and is more frequent in men (5.72%) than women (2.31%) (p < 0.001). Genital lesions were significantly associated with male sex, infection by high-risk and multiple HPV types, having more than two sexual partners in the last year, smoking status and the presence of other STI. While alcohol use was associated with a higher prevalence of EGL in women, same-sex sexual relationship increase the prevalence in men. In the EGL group, 67.79% (p = 0.032) were positive for HPV infection and the types HPV6 and HPV11 were the most prevalent ones. Conclusion The prevalence of EGL in young adults was consistently high, and most cases were associated with genital HPV infection and STIs. Although men have a higher prevalence, both sexes share most genital lesion determinants. The promotion of sexual education and vaccination especially focus in young men, who are usually outside the targets of primary health care programmes, can prevent EGL in Brazilian young adults.

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Human papilloma virus: from understanding of immunopathogenesis to rational tactics of management

GYNECOLOGY ◽

10.26442/2079-5696_2018.3.5-11 ◽

2018 ◽

Vol 20 (3) ◽

pp. 5-11 ◽

Cited By ~ 4

Author(s):

A L Tikhomirov ◽

S I Sarsaniya ◽

G A Filatova

Keyword(s):

Human Papilloma Virus ◽

Sexually Transmitted Infection ◽

Hpv Infection ◽

Sexually Active ◽

Transmitted Infection ◽

Papilloma Virus ◽

Sexually Transmitted ◽

Active Population ◽

The World ◽

Epithelial Lesions

The human papilloma virus (HPV) is the most common sexually transmitted infection. 440 million people in the world suffer from HPV infection of the genital. During the life of HPV, 50 to 80% of the sexually active population is infected, most often in the first years of sexual activity (the maximum prevalence is between 18-30 years of age). The treatment of subclinical forms of HPV epithelial lesions in 115 patients aged 26 to 42 years with a normal colposcopic pattern and the presence of coilocytosis was performed.

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Genotyping of Human Papilloma Virus (HPV) in female condyloma acuminata patient in Dr. Soetomo Hospital, Surabaya

Dermatology Reports ◽

10.4081/dr.2019.8062 ◽

2019 ◽

Author(s):

Afria Arista ◽

Dwi Murtiastutik ◽

Trisniartami Setyaningrum ◽

Gondo Mastutik

Keyword(s):

Human Papilloma Virus ◽

Hpv Infection ◽

Cross Sectional Study ◽

Condyloma Acuminata ◽

Multiple Infection ◽

Transmitted Infection ◽

Cross Sectional ◽

Papilloma Virus ◽

Sexually Transmitted ◽

Polymerase Chain

Human Papilloma Virus (HPV) cause the most common sexually transmitted infection in women. HPV may lead to clinical manifestation as condyloma acuminata. The type of HPV are divided into two categories: low risk and high risk. Objective: To determine the type of HPV in female condyloma acuminata patient. Material and methods: A cross sectional study was conducted in Dermatology Venereology Outpatient Clinic Dr. Soetomo Hospital Surabaya from February, 2007 to May, 2007. A total of 13 female patients with condyloma acuminata were includ in this study. Nucleic acids amplification assays (Polymerase Chain Reaction) used to detect the HPV infection. Results: Condyloma acuminata mostly caused by HPV-11 (30,76%) and HPV-6 (23,07%). Only 1 patient in this study caused by HPV 18. 38% of condyloma acuminata in this study caused by multiple infection of HPV. Conclusion: Molecular assay are gold standard to identification of HPV in the condyloma acuminata patient.

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ASSOCIATION OF THE PERCEIVED SEVERITY OF THE HUMAN PAPILLOMAVIRUS WITH THE PREVENTIVE INTENTION OF HPV INFECTION IN MALE ADOLESCENTS: A CROSS-SECTIONAL SURVEY

Journal of Men s Health ◽

10.22374/jomh.v15i2.127 ◽

2019 ◽

Vol 15 (2) ◽

pp. e47-e57 ◽

Cited By ~ 1

Author(s):

Hae Won Kim ◽

Seung Eun Kim ◽

Hae Young Ahn ◽

Eun Ju Lee ◽

Jung Lim Lee ◽

...

Keyword(s):

Human Papillomavirus ◽

School Health ◽

Hpv Infection ◽

Sexual Relationships ◽

Cross Sectional Survey ◽

Transmitted Infection ◽

Cross Sectional ◽

Sexually Transmitted ◽

Male Adolescents ◽

Preventive Vaccination

Background and objective The human papillomavirus (HPV) infection is usually asymptomatic, may affect both sexes, and is easily transmitted. Providing male adolescents with information about HPV prevention before sexually active state is important. This study was designed to gain a better understanding of the perceptions on HPV severity, knowledge on ways to prevent HPV infection, and influencing factors toward preventive measures in male adolescents. Materials and methods A self-administered questionnaire was completed by students aged 13–17 years from six schools in Seoul and the surrounding metropolitan area, from October to December 2014. A total of 615 male adolescents participated in this cross-sectional survey. Results Only 58 (9.5%) boys had heard of HPV. They perceived HPV infection as a disease more severe in girls. Perceptions of HPV as a sexually transmitted infection (STI) in boys (adjusted odds ratio [AOR] 1.79, 95% confidence interval [CI]: 1.00–3.19, p<0.05) and a cause of cancer in girls (AOR=2.69, 95% CI=1.26–5.84, p<0.05) were associated with the intention to maintain monogamous sexual relationships. Alcohol consumption was associated with the intention of postponing sexual intercourse (AOR=0.53, 95% CI=0.34–0.82, p<0.01) and having a sister was associated with the intention of being vaccinated against HPV (AOR=1.48, 95% CI=1.03–2.13, p<0.05). Conclusions Increasing awareness on the severity of HPV affected the intentions of male adolescents to prevent HPV infection. Efforts should be made to maximize awareness of HPV as a causative agent of cancer and a common STI in both boys and girls. Education materials on the influence of HPV infection and steps to be taken for proactive prevention should be included in school health subjects. Special consideration should be given for the preventive vaccination of male adolescents nationwide.

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Sexually transmitted infection testing awareness, uptake and diagnosis among urban refugee and displaced youth living in informal settlements in Kampala, Uganda: a cross-sectional study

BMJ Sexual & Reproductive Health ◽

10.1136/bmjsrh-2019-200392 ◽

2019 ◽

Vol 46 (3) ◽

pp. 192-199 ◽

Cited By ~ 1

Author(s):

Carmen Helen Logie ◽

Moses Okumu ◽

Simon Mwima ◽

Peter Kyambadde ◽

Robert Hakiza ◽

...

Keyword(s):

Young Women ◽

Sex Partners ◽

Transmitted Infection ◽

Cross Sectional ◽

Sti Prevention ◽

Sexually Transmitted ◽

Factors Associated ◽

Sti Testing ◽

Social Ecological ◽

Related Stigma

BackgroundSexually transmitted infection (STI) prevention needs among urban refugee and displaced youth are understudied. The study objective was to explore factors associated with the STI prevention cascade (STI services awareness, testing, diagnosis) among urban refugee and displaced youth in Kampala, Uganda.MethodsWe implemented a cross-sectional survey with youth aged 16–24 years in informal settlements in Kampala. We conducted bivariate and multivariable logistic regression analyses to identify social ecological (intrapersonal, interpersonal, community) level factors associated with STI testing services awareness, lifetime STI testing, and lifetime STI diagnosis.ResultsParticipants (n=445; mean age 19.3, SD 2.6, years) included young women (n=333, 74.8%) and young men (n=112, 25.2%). Less than half (43.8%) were aware of community STI services. One-quarter (26.1%) reported lifetime STI testing. Of these, 39.5% reported a lifetime STI diagnosis. In multivariable analyses among young women, age, lifetime sex partners, and lower adolescent sexual and reproductive health (SRH)-related stigma were associated with STI services awareness; and age, lower adolescent SRH-related stigma, and food security were associated with STI testing. Among young men, time in Uganda and lower HIV-related stigma were associated with STI services awareness; and age, condom self-efficacy, and increased adolescent SRH-related stigma were associated with testing. Lifetime sex partners, lower condom self-efficacy, and lower adolescent SRH-related stigma were associated with lifetime STI diagnosis.ConclusionsSocial ecological factors including stigma (adolescent SRH-related, HIV-related) were associated with STI testing and diagnosis among young urban refugees. Gender, age and stigma-tailored strategies can advance the STI prevention cascade among urban young refugees.

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Association of TNF-α-308G/A and IL-18 Polymorphisms with risk of HPV infection among sexually active women in Burkina Faso

BioMolecular Concepts ◽

10.1515/bmc-2020-0008 ◽

2020 ◽

Vol 11 (1) ◽

pp. 97-101

Author(s):

Ina M. A. Traore ◽

Théodora M. Zohoncon ◽

Florencia W. Djigma ◽

T. Rebeca Compaore ◽

Yves Traore ◽

...

Keyword(s):

Burkina Faso ◽

Genetic Factors ◽

Hpv Infection ◽

Sexually Active ◽

Allelic Discrimination ◽

Transmitted Infection ◽

Sexually Transmitted ◽

Coding Regions ◽

Tnf Α ◽

High Risk Hpv

AbstractHuman papillomavirus (HPV) infection is the most common sexually transmitted infection worldwide. Persistence infection can lead to the development of cervical cancer potentially due to some genetic factors such as polymorphisms in regulatory and coding regions of cytokine genes. The purpose of this study was to determine whether there is a relationship between TNF-308 G/A or IL18 polymorphisms and high-risk HPV infection among sexually active women from Burkina Faso. Ninety-one HPV infected and two hundred and nine HPV negative women (the latter used as healthy controls) were screened. TNFA-308 G/A and IL18-607 C/A polymorphisms were detected using the TaqMan allelic discrimination. HPV 52 (21.19%), HPV 39 (11.86%) and HPV 33 (11.02%) were the most common HPV genotypes. The TNFA-308A and IL18-607 C alleles were predominant in all women in the study. None of the TNFA and IL18 alleles were associated with HPV infection. The results suggest that there is no relationship between TNF-308 G/A or IL18-607C/A polymorphisms and HPV infection among women in the study.

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