scholarly journals Chronic diseases and multimorbidity among unemployed and employed persons in the Netherlands: a register-based cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e035037
Author(s):  
Berivan Yildiz ◽  
Merel Schuring ◽  
Marike G Knoef ◽  
Alex Burdorf
Keyword(s):  
The Netherlands ◽  
Chronic Diseases ◽  
Employment Status ◽  
Inflammatory Diseases ◽  
Multiple Logistic Regression Analysis ◽  
Medication Use ◽  
Psychological Disorders ◽  
Sociodemographic Characteristics ◽  
Cross Sectional ◽  
Inflammatory Conditions

ObjectivesThe first objective of this study was to describe the age-specific prevalence of chronic diseases and multimorbidity among unemployed and employed persons. The second objective was to examine associations of employment status and sociodemographic characteristics with chronic diseases and multimorbidity.DesignData linkage of cross-sectional nationwide registries on employment status, medication use and sociodemographic characteristics in 2016 was applied.SettingRegister-based data covering residents in the Netherlands.Participants5 074 227 persons aged 18–65 years were selected with information on employment status, medication use and sociodemographic characteristics.Outcome measuresMultiple logistic regression analysis and descriptive statistics were performed to examine associations of employment and sociodemographic characteristics with the prevalence of chronic diseases and multimorbidity. The age-specific prevalence of six common chronic diseases was described, and Venn diagrams were applied for multimorbidity among unemployed and employed persons.ResultsUnemployed persons had a higher prevalence of psychological disorders (18.3% vs 5.4%), cardiovascular diseases (20.1% vs 8.9%), inflammatory diseases (24.5% vs 15.8%) and respiratory diseases (11.7% vs 6.5%) than employed persons. Unemployed persons were more likely to have one (OR 1.30 (1.29–1.31)), two (OR 1.74 (1.73–1.76)) and at least three chronic diseases (OR 2.59 (2.56–2.61)) than employed persons. Among unemployed persons, psychological disorders and inflammatory conditions increased with age but declined from middle age onwards, whereas a slight increase was observed among employed persons. Older persons, women, lower educated persons and migrants were more likely to have chronic diseases.ConclusionLarge differences exist in the prevalence of chronic diseases and multimorbidity among unemployed and employed persons. The age-specific prevalence follows a different pattern among employed and unemployed persons, with a relatively high prevalence of psychological disorders and inflammatory conditions among middle-aged unemployed persons. Policy measures should focus more on promoting employment among unemployed persons with chronic diseases.

scholarly journals The concurrence of chronic diseases among unemployed and employed persons: a register-based study

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
B Yildiz ◽  
M Schuring ◽  
M G Knoef ◽  
L van Zoonen ◽  
A Burdorf
Keyword(s):  
Chronic Diseases ◽  
Employment Status ◽  
Older Persons ◽  
Large Scale ◽  
Middle Age ◽  
Inflammatory Diseases ◽  
Psychological Disorders ◽  
Respiratory Illness ◽  
Sociodemographic Characteristics ◽  
Objective Data

Abstract Background The first aim of this study was to describe the prevalence of chronic diseases and multimorbidity among employed and unemployed persons. The second aim was to investigate associations of sociodemographic characteristics with the prevalence of chronic diseases and multimorbidity. Methods Data linkage of large-scale registries on employment status, medication use and sociodemographic characteristics for all Dutch residents in 2016 was applied. In total, 5,074,227 subjects aged 18-65 years were included in the study. The prevalence of six common chronic diseases and multimorbidity was investigated among unemployed and employed persons. Multivariate logistic regression analyses were performed to examine associations of sociodemographic characteristics with the prevalence of chronic diseases and multimorbidity. Results Unemployed persons had a higher prevalence of psychological disorders (18.3% vs 5.4%), cardiovascular disease (20.1% vs 8.9%), inflammatory diseases (24.5% vs 15.8%), and respiratory illness (11.7% vs 6.5%) compared to employed persons. Unemployed persons were more likely to have one (OR 1.30, 95% CI 1.29-1.31), two (OR 1.74, 95% CI 1.73-1.76) and at least three chronic diseases (OR 2.59, 95% CI 2.56-2.61) than employed persons. Older persons, women, lower educated persons and migrants were more likely to have one, two, and at least three chronic diseases. Especially at younger ages, psychological disorders and inflammatory conditions were more prevalent but declined from middle age onwards among unemployed persons, whereas as slight increase from middle age onwards was observed among employed persons. Conclusions Using objective data, this study provided evidence for inequalities in the prevalence of chronic diseases and multimorbidity, indicating employment status to be an important determinant of health. Policy measures and health interventions should target chronic diseases and multimorbidity, especially among unemployed persons. Key messages Using objective data, this study showed that unemployed persons had a higher prevalence of chronic diseases and multimorbidity compared to employed persons. In particular older persons, women, lower educated persons and migrants were more likely to have chronic diseases and multimorbidity.

scholarly journals Associations Between Telomere Length and Insulin Resistance in American Adults：A Cross-Sectional Study from the US National Health and Nutrition Examination Survey, 1999–2002

2021 ◽  
Author(s):  
Rongpeng Gong ◽  
Zheng Li ◽  
Ya Liu ◽  
Gang Luo ◽  
Lixin Yang ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Telomere Length ◽  
Chronic Diseases ◽  
Weak Link ◽  
Multiple Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Logistic Analysis ◽  
Health And Nutrition ◽  
Arterial Aging

Abstract BackgroundSome previous studies seemed to confirm a link between telomere length and many chronic diseases, but in recent years, a growing body of evidence has shown a weak link between telomere length and some chronic diseases. In previous studies insulin resistance has been listed as a sign of arterial aging, diabetes, and especially atherosclerosis. However, there is insufficient evidence that telomere length is associated with insulin resistance in US adults. Therefore, we tried to find evidence of telomere length and insulin resistance based on the NHANES1999-2002 database.MethodsWe used multiple logistic regression analysis to test the relationship between telomere length and insulin resistance, and drew a smooth fitting curve between telomere length and insulin resistance without adjustment. At the same time, groups of people were divided according to age, gender, race, etc., and multivariate Logistic analysis was conducted after adjusting covariables to test the association between telomere length and insulin resistance in different groups.ResultsIn this study, after the adjustment of covariables. Telomere length was not associated with insulin resistance in U.S. adults and was not statistically significant.ConclusionsSince there is a significant association between insulin resistance and race, further investigation and study is needed to determine whether telomere length is related to the risk of insulin resistance in other populations. At the same time, more research is needed to explore the link between telomeres and chronic disease in the future.

scholarly journals Continued medication use in dentistry: the importance of dental records

2017 ◽  
Vol 4 (3) ◽  
pp. 81
Author(s):  
Glaucia Helena Faraco De Medeiros ◽  
Vanessa Brüning
Keyword(s):  
Arterial Hypertension ◽  
Chronic Diseases ◽  
Heart Diseases ◽  
Medication Use ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Systemic Arterial Hypertension ◽  
Dental Records ◽  
School Of Dentistry

Aim: Appoint the main chronic diseases and the most frequent medications used by the patients by the graduation students of Dentistry between 2012 and 2014/A,through patients’dentistry records.Material and Methods: Two studies were performed: one retrospective in patients’ dentistry records, attended at the Clinical School of Dentistry and a cross-sectional study with the students enrolled between the 6th and 9th semester in 2014/B. After the record, the data were inserted on an Excel® spreadsheet to posterior analysis by simple frequency.Results: Eighty-eight charts were evaluated and applied a questionnaire to 61 students. The most prevalence disease in the attended patients at the clinic and mentioned by the students was the systemic arterial hypertension, 77.25% and 60.66% respectively. Fifty-eight students (95%) affirmed confirming the patients’ anamnesis with systemic arterial hypertension, mellitus diabetes and chronic disease. The most used medications by these patients are those to control the systemic arterial hypertension, mellitus diabetes and heart diseases. Seventy-two percent affirmed interest on the purpose of patients’ medication; 32.79% say to research about their interaction. By dentistry records analyzed we found that only 5.6% took notes about the time of use of the medications.Conclusions: The chronic diseases most found in patients were the arterial hypertension, mellitus diabetes and heart diseases. The main medications are used to control diseases previously mentioned. One update of anamnesis record is suggested by the students.

scholarly journals How Do Health and Social Networks Compare between Low-Income Multiproblem Households and the General Population?

2019 ◽  
Vol 16 (24) ◽  
pp. 4967 ◽  
Author(s):  
Gera E. Nagelhout ◽  
Latifa Abidi ◽  
Hein de Vries
Keyword(s):  
Mental Health ◽  
Social Networks ◽  
General Population ◽  
The Netherlands ◽  
Low Income ◽  
Multiple Logistic Regression Analysis ◽  
Group Versus ◽  
Perceived Health ◽  
Cross Sectional Survey ◽  
Cross Sectional

Multiproblem households that receive social care for multiple problems, such as debts, psychiatric disorders, and domestic violence, may also be disadvantaged in terms of health and social networks. This study examines whether low-income multiproblem households and the general population differ in self-perceived health, mental health, health behaviors, and social networks. We performed a cross-sectional survey among respondents from low-income multiproblem households (n = 105) and the general population (n = 99) in the municipality of Apeldoorn in the Netherlands. Comparisons with national statistics data indicated that our sample of multiproblem households is more disadvantaged in terms of self-perceived health and mental health than low socioeconomic groups in general in the Netherlands. A multiple logistic regression analysis showed that being part of the multiproblem household group versus the general population group was associated with a lower educational level, a lower likelihood of being in paid employment, a lower score with respect to mental health, less alcohol consumption, and less fruit consumption. There were also differences between the groups on other variables, but these were not significant in adjusted analyses. In conclusion, multiproblem households in Apeldoorn had lower scores on mental health, drank fewer alcoholic drinks per week, and ate less fruit than the general population.

scholarly journals Excess in Atherosclerotic and Inflammametabolic Diseases Are Differentially Expressed in Myelodysplasia and Are Highly Dependent on Age, R-IPSS and Ethnicity

Blood ◽  
2018 ◽  
Vol 132 (Supplement 1) ◽  
pp. 4855-4855
Author(s):  
Gustavo A. Rivero ◽  
Elias Perli ◽  
Stephanie Moreno ◽  
Jason L Salemi ◽  
Jason L Salemi
Keyword(s):  
High Risk ◽  
Major Depression ◽  
Germ Line ◽  
Conflicts Of Interest ◽  
Inflammatory Diseases ◽  
Prognostic Score ◽  
The United States ◽  
Cross Sectional ◽  
Healthy Elderly ◽  
Inflammatory Conditions

Abstract Background Myelodysplastic syndrome (MDS) is an inflammatory heterogeneous group of myeloid disorders with variable risk for acute myeloid leukemia (AML) conversion. Recent reports highlight that mutations [i.e. TET2, DNMT3A, AXSL1] configurate not only risk for malignant conversion in "healthy elderly individuals" but also 'directly' participate in coronary artery disease [CAD] development. TET2 clonal hematopoiesis [TET2 CHIP] accelerates atherosclerosis in mice via monocytic inflammatory amplification. Indeed, germ-line DNMT3A human disease phenocopy obesity and neurocognitive abnormalities suggesting that a more complex, but still poorly characterized cardiometabolic risk, probably originates from patient predisposition and somatic mutation acquisition. We seek to originate a cross-sectional "proof of concept" for quantifying the association between myelodysplasia [a clonal disorder initiated by CHIP mutations] and several systemic inflammatory conditions [i.e. CAD, peripheral vascular disease (PVD), obesity, depression and COPD]. Methods: A cross-sectional analysis of a nationally-representative sample of inpatient hospitalizations in the United States between 2007 and 2015 [750,249 MDS-related hospitalizations, or 83,361 hospitalizations per year] was performed to identify co-occurring inflammatory diseases during hospitalizations in patients older than 35 years, in which MDS was documented. Given the inflammatory nature of the disease, subgroups were defined to investigate the prevalence of individual inflammatory domains (per 1,000 MDS-related hospitalizations) according to Revised-International Prognostic Score System [R-IPSS]. Subgroup analysis was performed for patients based on age (above and below 65 years), and race/ethnicity. Prevalence and confidence intervals [CI] were obtained for each inflammatory condition. "Relevant" inflammatory domains were considered statistically significant based on non-overlapping 95% CIs. Results: In examined admissions, prevalence for CAD in (Low-risk) LR- MDS age <> 65 was 12.2 vs 24.7, PVD 21.8 vs 60.2, [Fig 1 A and B] obesity 88.1 vs 51.7, major depression 14.6 vs 5.3, COPD 42.1 vs 70.7, p=0.0001 for all comparisons [Fig 1 B and C]. Conversely, prevalence for CAD in (High-risk) HR MDS age <> 65 was 9.1 vs 17.3, p=0.04; PVD 14.5 vs 43.2, p=0001; obesity 73.7 vs 42.2, p=0.003 major depression 5.1 vs 6.9, p=0.04 and COPD 23.0 vs 34.6, p=0.05. Differential prevalence expression for CAD was observed between non-Hispanic Whites (W) and Hispanics (H) [22 vs 28, p=0.02]. PVD was more prevalent, in both W vs H [64.6 and 52.2, p= 0.0002] and NH-Blacks/African Americans (AA) vs H [63.1 vs 52.2, p= 0.009]. Obesity was more prevalent among AA and H [64.1 and 62.9, respectively] than in W [51.9, p=0.009 for W vs AA and p=0.0002 for W vs H]. Similar expression for diabetes was observed between H vs W [404 vs 282, p<0.0001], H vs AA [404 vs 364, p=0.0001], and AA vs W [364 vs 282, p=<0.0001]. COPD was dominant among W and AA [73.8 and 78.4] as compared with H [50.4, p=0.0001 for H vs W and H vs AA]. Idiopathic pulmonary fibrosis was dominant in W and H [1.8 and 1.9] in comparison to AA [0.9, p=0.04 AA vs H and p=0.02 AA vs W]. Major depression prevalence was observed in AA, W and H in 5.4 vs 9.5 vs 14.3, respectively, p=0.0001 H vs AA and H vs W]. Conclusions. Prevalence of systemic inflammatory diseases in MDS are associated with age, disease biology [Low vs High risk] and ethnicity. Cardiopulmonary complications, such as PVD+ COPD are dominant in W and AA. Lower prevalence for PVD and COPD, but high rates for CAD, depression, diabetes and IPF in H vs W and AA suggest that ethnicity could differentially drive cardiometabolic and inflammametabolic phenotypes when co-occurring with clonal hemopoietic disorders such as MDS. Disclosures No relevant conflicts of interest to declare.

scholarly journals An association analysis between hypertension, dementia, and depression and the phases of pre-sarcopenia to sarcopenia: A cross-sectional analysis

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0252784
Author(s):  
Takeshi Endo ◽  
Kenju Akai ◽  
Tsunetaka Kijima ◽  
Shigetaka Kitahara ◽  
Takafumi Abe ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Chronic Diseases ◽  
Handgrip Strength ◽  
Multiple Logistic Regression Analysis ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Japanese Island ◽  
Cross Sectional ◽  
Adult Participants ◽  
Sectional Analysis

Sarcopenia is intricately related to aging associated diseases, such as neuropsychiatric disorders, oral status, and chronic diseases. Dementia and depression are interconnected and also related to sarcopenia. The preliminary shift from robust to sarcopenia (i.e., pre-sarcopenia) is an important albeit underdiscussed stage and is the focus of this study. Identifying factors associated with pre-sarcopenia may lead to sarcopenia prevention. To separately examine the effects of dementia and depression on pre-sarcopenia/sarcopenia, we conducted multiple analyses. This cross-sectional study used health checkup data from a rural Japanese island. The participants were aged 60 years and above, and the data included muscle mass, gait speed, handgrip strength, oral status (teeth and denture), chronic diseases (e.g., hypertension), dementia (cognitive assessment for dementia, iPad Version), and depression (self-rating depression scale). A total of 753 older adult participants were divided into the sarcopenia (n = 30), pre-sarcopenia (n = 125), and robust (n = 598) groups. An ordered logit regression analysis indicated that age and depression were positively correlated with sarcopenia, while hypertension was negatively associated with it. A multiple logistic regression analysis between the robust and pre-sarcopenia groups showed significant associations between the same three variables. Depression was associated with pre-sarcopenia, but not dementia. There was also a significant association between hypertension and pre-sarcopenia. Further research is needed to reveal whether the management of these factors can prevent sarcopenia.

scholarly journals Influence of the COVID-19 Pandemic on Household Food Waste Behavior in Japan

2020 ◽  
Vol 12 (23) ◽  
pp. 9942
Author(s):  
Kun Qian ◽  
Firouzeh Javadi ◽  
Michikazu Hiramatsu
Keyword(s):  
Food Waste ◽  
Employment Status ◽  
Social Consciousness ◽  
Economic Consequences ◽  
Sociodemographic Characteristics ◽  
Cross Sectional ◽  
Household Food ◽  
The Social ◽  
And Behaviors ◽  
And Behavior

The 2019 coronavirus disease (COVID-19) pandemic had various influences on people’s ordinary lives, including their thoughts and behaviors related to food consumption. Food waste has been cited as a serious issue with environmental, social, and economic consequences. In this study, we investigated how the COVID-19 pandemic altered the social consciousness and behavior related to food waste in Japan. We conducted a nationwide online-based survey and collected a cross-sectional dataset from 1959 adult respondents. The results showed that people in regions highly impacted by the pandemic reported a clearer understanding of the situation of their household food waste, more careful food preparation and purchasing, and were more strongly influenced to change their behaviors due to COVID-19. Further analyses revealed that thoughts and behaviors related to food waste significantly differed by sociodemographic characteristics, such as gender, household size, and employment status. This study also implied that the COVID-19 pandemic encouraged some improvements in peoples’ behaviors and thoughts with regard to food, such as paying attention to food waste, making efforts to reduce food waste, and attempting cooking by themselves at home.

scholarly journals Knowledge, Attitude and Behaviours Regarding Medication Use among Older People Suffering from Chronic Diseases

2020 ◽  
Author(s):  
Ilknur Ozkan ◽  
Feride Taskin Yilmaz ◽  
Azime Karakoc Kumsar ◽  
Kamile Uyar
Keyword(s):  
Drug Use ◽  
Chronic Diseases ◽  
Medication Use ◽  
Family Health ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Self Medication ◽  
Cross Sectional ◽  
Elderly Individuals ◽  
Disease Information

Introduction: Physiological changes occurring with aging increase prevalence of chronic diseases in elderly individuals. This situation brings about difficulties in medication use in elderly individuals. This study was conducted to determine knowledge, attitude and behaviours regarding medication use in elderly with chronic diseases. Methods: Participants of this descriptive and cross-sectional study were 124 elderly individuals who were more than 65 years old, applied to Family Health Center in Yalova, Turkey between the dates of January- June 2018. Data were collected with data collection form including individual and disease information, medication use and knowledge, attitude and behaviours regarding medication use. Results: Almost half of the elderly individuals (44.4%) expressed that they used medicine three times a day and 40.3% of them expressed that they used medicine six times and more a day. When the information about medication use of elderly individuals is evaluated, 75% of them stated that they did not receive any information on drug use and 82.3% of them did not know the side effects of drugs. When the attitudes of the individuals were evaluated, it was found that 6.5% of them liked to use medication, 67.7% of them had no dose, and 46% of them had stopped using medication without asking the physician. When the behaviors of elderly individuals were evaluated, 19.4% of them didn’t use their medicines regularly, 46% of them discontinued their medication without asking their doctors, 82.3% of them didn’t know side effect of the medicines, 81.5% of them used medicines without doctor’s advice, 79.8% of them didn’t read medicine usage instructions before using medicines, 12.9% of them kept their medicines in their bags and 55.6% of them kept them in a cabinet. Conclusion: Significant problems such as lack of information about drug use in elderly individuals and self-medication use have been identified.

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