Topical sunscreens

1990 ◽  
Vol 28 (16) ◽  
pp. 61-63
Keyword(s):  
Risk Factor ◽  
Skin Cancer ◽  
Uv Radiation ◽  
Ozone Layer ◽  
The Earth

Ultraviolet (UV) radiation reaching the earth consists of UVB (wavelengths 290–320 nanometres) and UVA (320–400nm). UVC (100–290nm) is still stopped by the ozone layer. UVB causes sunburn, but both UVB and UVA cause skin cancer and skin ageing. Severe sunburn may be a risk factor for melanoma.1 Numerous sunscreens are used to prevent sunburn or to protect patients with photodermatoses; which ones should be recommended?

scholarly journals The Effect of Increased UV-B Radiation on the Terrestrial Ecosystem

2019 ◽  
Vol 7 (8) ◽  
pp. 1173
Author(s):  
Mehtap Gürsoy
Keyword(s):  
Adverse Effects ◽  
Natural Resources ◽  
Uv Radiation ◽  
Terrestrial Ecosystem ◽  
Biomass Accumulation ◽  
Ozone Layer ◽  
The Earth ◽  
Physiological Structure ◽  
Harmful Effects

Against rapidly developing industry and increasing population, natural resources on earth are getting destroyed. One of the most important adverse effects on the environment is perhaps the depletion of ozone layer which protects the earth from harmful effects of UV radiation, especially UV-B. The effect of UV-B radiation can vary according to species. At high rates of UV-B radiation, many disorders in DNA, photosynthesis, morphological and physiological structure, and biomass accumulation in plants are observed. In this review, the effects of high UV-B radiation on terrestrial ecosystem are discussed.

scholarly journals Incidencia de cáncer de piel en población de Machala, Ecuador. //Incidence of lean cancer in the population of Machala, Ecuador.

Ciencia Unemi ◽  
2018 ◽  
Vol 11 (27) ◽  
pp. 78-86
Author(s):  
Adriana Lam-Vivanco ◽  
Flor Espinoza-Carrión ◽  
Jovanny Santos Luna ◽  
Carlos García-González
Keyword(s):  
Skin Cancer ◽  
Uv Radiation ◽  
Basal Cell ◽  
Descriptive Study ◽  
Clinical Analysis ◽  
Ozone Layer ◽  
Health Centers ◽  
Sex Type ◽  
High Incidence ◽  
Cáncer De Piel

La acción de agentes genotóxicos, como es el caso de la radiación UV, está en mayor incidencia sobre la tierra como producto a la reducción de la capa de ozono, dando como resultado la producción de mutaciones sobre ADN, Es un estudio, retrospectiva-descriptivo, con el objetivo determinar la incidencia de cáncer de piel mediante un análisis expedientes clínicos evaluados con biopsias de neoplasia cutáneas malignas en el periodo 2009- 2015, con variables de edad, sexo, tipo de neoplasia. Con un total de 1262 pacientes atendidos en  centro de salud privada, de la ciudad de Machala, se obtuvieron los datos 58%(709) masculinos y 42%(553) mujeres, se encontró un índice de 28.09% en sexo masculino y 32% según sexo femenino, en el año 2015 donde se observa un crecimiento de la población  en el periodo 2009-2015.  El grupo etario con alta incidencia según el género masculino: es 65-69 años lo que representa 15,0754% y en los pacientes de sexo femenino con un rango de edad:  50-54 años es de16.95% , se demostró que una de las ocupaciones con mayor incidencia de cáncer de piel se encuentra en los profesores en género masculino 29,31%(34 ) y femenino 25.4%(32), presentando C. Basocelular 58.29%(116 ) masculinos y 71.75%(127) femenino, atendidos en consultorio de atención privada, en la ciudad de Machala en el año 2015.AbstractThe action of genotoxic agents; such as, UV radiation , hasa  greater incidence on land as a result  of the reduction of the ozone layer, resulting on mutations on DNA. In a retrospective-descriptive study to determine the incidence of skin cancer through clinical analysis records which were  evaluated with biopsies of neoplasia skin malignant in the period 2009-2015 , with variables of age, sex, type of neoplasia. With a total of 1262 patients cared for in private health centers, in Machala City, the results included 58,18% (709) male and 42% (553) women. It was found a rate of 28.09% present in males and 32% on female sex, by the year 2015, showing a growth of the population from 2009 to 2015. The group age with a high incidence according to the gender male: is 65-69 years which represents 15, 0754% (30), female patients with a range of age: 50-54 years is 16.95% (30). It was showed that male teachers had the greatest incidence 29,31% (34) and women 25.4% (32), presenting  C. Basal cell 58.29% (116) in  men and 71.75% (127)in women, cared at private health centers, in Machala city in 2015.

scholarly journals Overall study on molecular pathways of skin cancer derived from Ultra- violet radiation as an environmental threat

2015 ◽  
Vol 16 (SE) ◽  
pp. 547-555
Author(s):  
Hossein Yousefi ◽  
Samira Mohammadzadeh ◽  
Arsalan Irompour ◽  
Neda Shenasifam ◽  
Elham Roshandel ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Ultraviolet Radiation ◽  
Cell Carcinoma ◽  
Uv Radiation ◽  
Ultra Violet ◽  
Ozone Layer ◽  
Molecular Pathways ◽  
Ultra Violet Radiation ◽  
Environmental Threat ◽  
Violet Radiation

An important part of solar radiation is considered to be Ultraviolet radiation. Though through passing ozone layer it is progressively filtered. Due to the depletion of the ozone layer, the filtering activity of the latter is reduced and as a result more UV radiation, UVB in particular, reaches the Earth’s surface. Ultraviolet radiation is composed of three different wavelengths: UVA, UVB and UVC. Although UVC isn't a cause of skin cancer, UVA and UVB play different roles as for tanning, burning, and photo aging. As a matter of fact, Ultraviolet light can damage DNA in the epidermis. However, through apoptosis the damaged DNA is repaired or deleted in order to prevent the generation of cancer. It is believed that a deficient apoptotic mechanism might make individuals liable to skin cancer. The main factor for generating skin cancer is considered to be the UV radiation which could cause basal cell carcinoma, squamous cell carcinoma and possibly melanoma. For the maintenance of hemostasis, apoptosis plays a key role. This is done via many molecular pathways such as the pathways of tumor suppressor genes like P53, P21 and also the expression of BAX proteins. These pathways are involved in apoptosis after UV radiation. It is clear that the malfunction of these genes and proteins can lower the tolerance of body and cause cancer. The goal of this article is to investigate the molecular pathways of skin cancer derived from Ultra violet radiation as an environmental threat.

Neutrophil Myeloperoxidase Destruction by Ultraviolet Irradiation

1988 ◽  
Vol 46 ◽  
pp. 138-139
Author(s):  
J. Hanker ◽  
B. Giammara ◽  
G. Strauss
Keyword(s):  
Uv Radiation ◽  
Myeloid Leukemia ◽  
Stratospheric Ozone ◽  
Psoriasis Patient ◽  
Whole Body ◽  
Human Neutrophils ◽  
Cupric Nitrate ◽  
The Earth ◽  
Routine Handling ◽  
Uvb Phototherapy

Only a fraction of the UV radiation emitted by the sun reaches the earth; most of the UVB (290-320nm) is eliminated by stratospheric ozone. There is increasing concern, however, that man-made chemicals are damaging this ozone layer. Although the effects of UV on DNA or as a carcinogen are widely known, preleukemia and acute myeloid leukemia (AML) have only rarely been reported in psoriasis patients treated with 8-methoxypsoralen and UV (PUVA). It was therefore of interest to study the effects of UV on the myeloperoxidase (MP) activity of human neutrophils. The peroxidase activity of enriched leukocyte preparations on coverslips was shown cytochemically with a diaminobenzidine medium and cupric nitrate intensification.Control samples (Figs. 1,4,5) of human bloods that were not specifically exposed to UV radiation or light except during routine handling were compared with samples which had been exposed in one of several different ways. One preparation (Fig. 2) was from a psoriasis patient who had received whole-body UVB phototherapy repeatedly.

ANDROID APPLICATION FOR DETECTION OF SKIN CANCER USING EXPERT SYSTEM

2018 ◽  
Vol 2 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Yogi Udjaja
Keyword(s):  
Risk Factor ◽  
Expert System ◽  
Skin Cancer ◽  
Cancer Cells ◽  
System Application ◽  
Ultraviolet Rays ◽  
The Sun ◽  
Android Application ◽  
Abnormal Growth ◽  
Skin Cells

Skin cancer is an abnormal growth of human skin that can damage skin cells. By knowing the symptoms of skin cancer as early as posssible, it is helpful in preventing the spread of cancer cells and treatment. There are many factors that cause skin cancer, but in general the cause is exposure to ultraviolet rays from the sun.  Therefore, an expert system application is required to detect skin cancer.  By using backward chining and probalility methode; which data is in form of someone’s risk factor and clinical sympthoms, then the application will provide temporary diagnosis.  This application is built in an android platfrom because in its development android is more used than other platforms. The accuracy obtained from this application is 96.67%.

Multiple Keratoacanthomas Arising Post-UVB Therapy

2004 ◽  
Vol 8 (4) ◽  
pp. 239-243 ◽  
Author(s):  
Kenneth J. Craddock ◽  
Jaggi Rao ◽  
Gilles J. Lauzon ◽  
Victor A. Tron
Keyword(s):  
Adverse Effect ◽  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Cell Carcinoma ◽  
Uv Radiation ◽  
Squamous Cell ◽  
Etiologic Agent ◽  
Etiologic Factor ◽  
Uv Treatment ◽  
Uvb Phototherapy

Background: Ultraviolet (UV) radiation is known to be an important etiologic agent in the development of skin cancer. Keratoacanthoma is an unusual, well-described cutaneous neoplasm that resembes squamous cell carcinoma but spontaneously resolves. Rarely, multiple keratoacanthomas may develop. Objective We present a case of multiple keratoacanthomas in a patient with psoriasis who had received UVB phototherapy. These lesions were hyperkeratotic papules, many of which spontaneously resolved and demonstrated the histologic characteristics of keratoacanthoma. Conclusion: We believe that UV radiation is the most likely etiologic factor in this patient's development of multiple keratoacanthomas. We wish to bring to the attention of clinicians this unusual adverse effect of UV treatment.

scholarly journals Platelet-activating Factor, a Molecular Sensor for Cellular Damage, Activates Systemic Immune Suppression

2002 ◽  
Vol 195 (2) ◽  
pp. 171-179 ◽  
Author(s):  
Jeffrey P. Walterscheid ◽  
Stephen E. Ullrich ◽  
Dat X. Nghiem
Keyword(s):  
Skin Cancer ◽  
Uv Radiation ◽  
Immune Suppression ◽  
Critical Role ◽  
Platelet Activating Factor ◽  
Cellular Damage ◽  
Uv Exposure ◽  
Delayed Type Hypersensitivity ◽  
Lipid Mediator ◽  
Paf Receptor

Ultraviolet (UV) radiation plays a critical role in the induction of nonmelanoma skin cancer. UV radiation is also immune suppressive, and the immune suppression induced by UV irradiation has been identified as a major risk factor for skin cancer induction. Previously, we showed that UV exposure activates a cytokine cascade involving prostaglandin (PG)E2, interleukin (IL)-4, and IL-10 that induces immune suppression. However, the earliest molecular events that occur immediately after UV exposure, especially those upstream of PGE2, are not well defined. UV-irradiated keratinocytes secrete the inflammatory phospholipid mediator, platelet-activating factor (PAF). Because PAF upregulates the production of immunomodulatory compounds, including PGE2, we tested the hypothesis that UV-induced PAF activates cytokine production and initiates UV-induced immune suppression. Both UV and PAF activated cyclooxygenase (COX)-2 and IL-10 reporter gene construct transcription. PAF mimicked the effects of UV in vivo and suppressed delayed-type hypersensitivity (DTH). Furthermore, immune suppression was blocked when UV-irradiated mice were injected with PAF receptor antagonists. In addition to the well-known role of PAF as a proinflammatory lipid mediator, we propose that the PAF receptor senses cellular damage through the recognition of PAF and/or PAF-like molecules, such as oxidized phosphatidylcholine, which activates cytokine transcription and induces systemic immune suppression.

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