Firearms, alcohol and crime: convictions for driving under the influence (DUI) and other alcohol-related crimes and risk for future criminal activity among authorised purchasers of handguns

2017 ◽  
Vol 24 (1) ◽  
pp. 68-72 ◽  
Author(s):  
Garen J Wintemute ◽  
Mona A Wright ◽  
Alvaro Castillo-Carniglia ◽  
Aaron Shev ◽  
Magdalena Cerdá
Keyword(s):  
Criminal Activity ◽  
Relative Increase ◽  
Criminal History ◽  
Driving Under The Influence ◽  
Important Predictor ◽  
Aggravated Assault ◽  
Firearm Violence ◽  
Fivefold Increase ◽  
Increase In Risk

Firearm violence frequently involves alcohol, but there are no studies of misuse of alcohol and risk for future violence among firearm owners. We examined the association between prior convictions for alcohol-related crimes, chiefly driving under the influence (DUI), and risk of subsequent arrest among 4066 individuals who purchased handguns in California in 1977. During follow-up through 1991, 32.8% of those with prior alcohol-related convictions and 5.7% of those with no prior criminal history were arrested for a violent or firearm-related crime; 15.9% and 2.7%, respectively, were arrested for murder, rape, robbery or aggravated assault. Prior alcohol-related convictions were associated with a fourfold to fivefold increase in risk of incident arrest for a violent or firearm-related crime, a relative increase greater than that seen for age, sex or prior violence. Prior convictions for alcohol-related crime may be an important predictor of risk for future criminal activity among purchasers of firearms.

Self-Help and Black Firearm Crime

2021 ◽  
pp. 001112872110226
Author(s):  
Candice Ammons-Blanfort ◽  
Stewart J. D’Alessio ◽  
Lisa Stolzenberg
Keyword(s):  
Racial Diversity ◽  
Police Department ◽  
Racially Diverse ◽  
Institutional Legitimacy ◽  
Aggravated Assault ◽  
Firearm Violence ◽  
Self Defense ◽  
Marginalized Groups ◽  
Self Help ◽  
Perception Of Police

Self-help theory posits that a negative perception of police engenders firearm violence rather than simply amplifying individuals’ ownership of firearms for self-defense. A racially diverse police force may help decrease firearm use among Black citizens because marginalized groups in society often view a governmental institution as legitimate and impartial when the racial composition of the institution mirrors the population it represents. Analyses using multilevel data show that as the racial diversity of a city’s police department increases, Black criminal offenders are much less likely to use a firearm in an aggravated assault and in a violent crime. These findings buttress the claim that the institutional legitimacy of a police agency can be enhanced by descriptive racial representation.

scholarly journals Use of incretin-based drugs and risk of cholangiocarcinoma: Scandinavian cohort study

Diabetologia ◽  
2021 ◽  
Author(s):  
Peter Ueda ◽  
Viktor Wintzell ◽  
Mads Melbye ◽  
Björn Eliasson ◽  
Ann-Marie Svensson ◽  
...  
Keyword(s):  
Incidence Rate ◽  
Cox Regression ◽  
Absolute Rate ◽  
Dipeptidyl Peptidase 4 ◽  
Rate Difference ◽  
Receptor Agonists ◽  
Dpp4 Inhibitors ◽  
Increased Risk ◽  
Increase In Risk

Abstract Aims/hypothesis Concerns have been raised regarding a potential association of use of the incretin-based drugs dipeptidyl peptidase 4 (DPP4) inhibitors and glucagon-like peptide-1 (GLP-1)-receptor agonists with risk of cholangiocarcinoma. We examined this association in nationwide data from three countries. Methods We used data from nationwide registers in Sweden, Denmark and Norway, 2007–2018, to conduct two cohort studies, one for DPP4 inhibitors and one for GLP-1-receptor agonists, to investigate the risk of incident cholangiocarcinoma compared with an active-comparator drug class (sulfonylureas). The cohorts included patients initiating treatment episodes with DPP4 inhibitors vs sulfonylureas, and GLP-1-receptor agonists vs sulfonylureas. We used Cox regression models, adjusted for potential confounders, to estimate hazard ratios from day 366 after treatment initiation to account for cancer latency. Results The main analyses of DPP4 inhibitors included 1,414,144 person-years of follow-up from 222,577 patients receiving DPP4 inhibitors (median [IQR] follow-up time, 4.5 [2.6–7.0] years) and 123,908 patients receiving sulfonylureas (median [IQR] follow-up time, 5.1 [2.9–7.8] years) during which 350 cholangiocarcinoma events occurred. Use of DPP4 inhibitors, compared with sulfonylureas, was not associated with a statistically significant increase in risk of cholangiocarcinoma (incidence rate 26 vs 23 per 100,000 person-years; adjusted HR, 1.15 [95% CI 0.90, 1.46]; absolute rate difference 3 [95% CI -3, 10] events per 100,000 person-years). The main analyses of GLP-1-receptor agonists included 1,036,587 person-years of follow-up from 96,813 patients receiving GLP-1-receptor agonists (median [IQR] follow-up time, 4.4 [2.4–6.9] years) and 142,578 patients receiving sulfonylureas (median [IQR] follow-up time, 5.5 [3.2–8.1] years) during which 249 cholangiocarcinoma events occurred. Use of GLP-1-receptor agonists was not associated with a statistically significant increase in risk of cholangiocarcinoma (incidence rate 26 vs 23 per 100,000 person-years; adjusted HR, 1.25 [95% CI 0.89, 1.76]; absolute rate difference 3 [95% CI -5, 13] events per 100,000 patient-years). Conclusions/interpretation In this analysis using nationwide data from three countries, use of DPP4 inhibitors and GLP-1-receptor agonists, compared with sulfonylureas, was not associated with a significantly increased risk of cholangiocarcinoma. Graphical abstract

scholarly journals The Criminal Histories of Drug-Drive Offenders

2018 ◽  
Vol 14 (2) ◽  
pp. 456-468 ◽  
Author(s):  
James Nunn
Keyword(s):  
Criminal Activity ◽  
Criminal History ◽  
First Year ◽  
Criminal Behaviour ◽  
Research Subjects ◽  
Criminal Sanctions ◽  
Criminal Histories ◽  
The Uk ◽  
High Level ◽  
Criminological Theories

Abstract This study examined the previous criminal behaviour of individuals who were arrested for violating the drug driving over the prescribed limit offence, introduced into the UK in March 2015. The sample consists of individuals arrested during the first year of enforcement of this offence from March 2015 to March 2016 within the jurisdictional boundaries of the Metropolitan Police Service in London. The previous criminal behaviour of the research subjects was framed within a number of criminological theories and there is examination of any correlation between their criminal history and the drug-driving offence they had been arrested for. The criminal activity was obtained from each individual’s criminal record held on the police national computer and coded with regards to offence groups. As well as criminal sanctions, there was also an examination of drug-related arrest histories. The results indicate a high level of previous criminal activity with drugs and driving matters dominating that activity. This supports the construct that, in this context, drug driving fits within their patterns of offending.

Abstract 14789: 2013 ACC/AHA Cholesterol Guideline Undertreats HIV-infected Adults With Carotid Atherosclerosis by Ultrasound

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Binh An P Phan ◽  
Bernard Weigel ◽  
Yifei Ma ◽  
Rebecca Scherzer ◽  
Danny Li ◽  
...  
Keyword(s):  
Carotid Atherosclerosis ◽  
Subclinical Atherosclerosis ◽  
Intima Media Thickness ◽  
Atherosclerotic Cardiovascular Disease ◽  
Antiretroviral Medication ◽  
Increased Risk ◽  
History Of ◽  
Ascvd Risk ◽  
Increase In Risk

Background: While HIV infection is associated with increased risk of ASCVD (atherosclerotic cardiovascular disease), it is unknown whether guidelines can identify HIV-infected adults who may benefit from statins. The purpose of our study was to compare the 2013 ACC/AHA and 2004 ATP III recommendations in a HIV population, and to evaluate associations with carotid artery intima-media thickness (CIMT) and plaque. Methods: We used ultrasound to measure CIMT at baseline and 3 years later in 352 HIV-infected adults with no ASCVD and not on statins. Plaque was defined as IMT > 1.5 mm. We compared 2013 ACC/AHA and 2004 ATP III recommendations, and evaluated associations with CIMT and plaque. Results: At baseline, the median age was 43 (IQR 39-49), 85% were male, 74% were on antiretroviral medication, and 50% had plaque. At follow-up, the median IMT progression was 0.052 mm/yr, and 66% had plaque. The 2013 guideline was more likely to recommend statins compared with the 2004 guideline, both overall (26% vs. 14%, p<.001), in those with plaque (32% vs. 17%, p=.0002), and in those without plaque (16% vs. 7%, p=.025). In unadjusted linear regression, the 2004 and 2013 risk score were strongly associated with CIMT (0.01 mm per 10% increase in risk, p<.001) and with CIMT progression (0.01 mm/yr per 10% increase in risk, p<.001). In multivariate analysis, older age, higher LDL-C, pack-years of smoking, and history of opportunistic infection were associated with baseline plaque. Conclusions: While the 2013 ACC/AHA guideline recommended statins to a greater number of HIV-infected adults compared to the 2004 ATP III guideline, both failed to recommend therapy in the majority of HIV-affected adults with carotid plaque. Both the 2004 and 2013 guidelines predicted higher levels of baseline CIMT and faster progression. HIV-specific guidelines that include detection of subclinical atherosclerosis may help to identify HIV-infected adults who are at increased ASCVD risk and may benefit from statins.

Addiction and Criminal Behavior: A Continuing Examination of Criminal Addicts

1976 ◽  
Vol 6 (2) ◽  
pp. 153-165 ◽  
Author(s):  
James C. Weissman ◽  
Samuel W. Marr ◽  
Paul L. Katsampes
Keyword(s):  
Criminal Behavior ◽  
Age Of Onset ◽  
Criminal Activity ◽  
Criminal History ◽  
Self Report ◽  
General Effect ◽  
Activity Increase ◽  
Race And Gender ◽  
Study Results ◽  
And Gender

The study proposed to examine the relationship between opiate addiction and criminal behavior. The study group was composed of general arrestee population subjects who were identified as regular opiate users. The subjects were interviewed to determine demographic, drug use, and self-report criminal history data; arrest data were collected from official records. The study addressed three research questions: (1) the general effect of addiction upon criminal activity; (2) the effect of addiction upon specific offense categories; and (3) the variations of the effects of addiction upon criminal activity relative to the age of onset of addiction, race, and gender. Study results showed dramatic increases in criminal activity associated with the onset of addiction. The criminal activity increase was displayed in violent crime categories, as well as property acquisitive and drug offense categories. Some differences were apparent according to age of onset of addiction, race, and gender, but the study design did not warrant the drawing of definitive conclusions regarding the differences.

scholarly journals Asthma and bronchiectasis exacerbation

2016 ◽  
Vol 47 (6) ◽  
pp. 1680-1686 ◽  
Author(s):  
Bei Mao ◽  
Jia-Wei Yang ◽  
Hai-Wen Lu ◽  
Jin-Fu Xu
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Respiratory Diseases ◽  
Forced Expiratory Volume ◽  
Lung Lesion ◽  
Duration Of Symptoms ◽  
Lesion Extension ◽  
Increase In Risk

Bronchiectasis and asthma are common respiratory diseases worldwide. However, the influence of asthma on bronchiectasis remains unclear. The objective of this study is to analyse the effects of asthma on bronchiectasis exacerbation.Data from inpatients diagnosed with bronchiectasis with or without asthma at Shanghai Pulmonary Hospital (Shanghai, China) between January 2013 and December 2014 were retrospectively collected and analysed. 249 patients with only bronchiectasis and 214 patients with both bronchiectasis and asthma were included in the study. Follow-up records were used to evaluate the effect of asthma on bronchiectasis exacerbation.The variables found to be independently associated with bronchiectasis exacerbations were age (OR 1.07, 95% CI 1.03–1.11; p<0.001), duration of symptoms (OR 1.06, 95% CI 1.03–1.09; p<0.001), the presence of asthma (OR 2.6, 95% CI 1.15–5.88; p=0.021), forced expiratory volume in 1 s <50% predicted (OR 4.03, 95% CI 1.75–9.26; p=0.001), isolation ofPseudomonas aeruginosain sputum (OR 2.41, 95% CI 1.00–5.79; p=0.05) and lung lesion extension to more than two lobes (OR 2.73, 95% CI 1.16–6.45; p=0.022).The existence of asthma was associated with an independent increase in risk of bronchiectasis exacerbation.

scholarly journals 400Overactive bladder with/without urinary incontinence and falls in the community-dwelling elderly

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Kenji Omae ◽  
Noriaki Kurita ◽  
Taro Takeshima ◽  
Toru Naganuma ◽  
Sei Takahashi ◽  
...  
Keyword(s):  
Older Adults ◽  
Logistic Regression ◽  
Fall Risk ◽  
Community Dwelling ◽  
Important Predictor ◽  
Multivariable Logistic Regression Analysis ◽  
Logistic Regression Models ◽  
Falls In Older Adults ◽  
Tree Approach

Abstract Background Little is known about the fall risk of older adults with overactive bladder (OAB), especially in the absence of urgency incontinence (UI). Methods This prospective cohort study included 630 community-dwelling, independent older adults 75 years old or older who attended a health check-up in 2017 with a 1-year follow-up. The associations of OAB with and without UI (OAB-wet and OAB-dry) with a fall history, and future fall risk compared to no OAB were assessed using logistic regression models. The contribution of OAB as a predictor of falls was examined using a random forest and decision tree approach. Results Of the 577 analyzed participants (median age 79 years), 273 were men. The prevalence of OAB-dry and OAB-wet at baseline was 15% and 14%, respectively. Multivariable logistic regression analysis revealed that both OAB-dry and OAB-wet were associated with a higher likelihood of prior falls (adjusted ORs vs no OAB 2.03 and 2.21, respectively; 95% CI 1.23–3.37 and 1.29–3.78, respectively). Among the 363 participants without a fall history, the adjusted ORs (95% CIs) of OAB-dry and OAB-wet for the occurrence of falls during the 1-year follow-up were 2.74 (1.19–6.29) and 1.35 (0.47–3.87), respectively. The tree-based approach used for all participants showed that OAB was an important predictor of falls in adults without a fall history. Conclusions OAB, even in the absence of UI, is an important predictor of falls in older adults with a low absolute fall risk. Key messages Our findings suggest that OAB is a risk factor for falls in the community-dwelling elderly irrespective of the presence of UI.

scholarly journals Can biopsies be omitted after normal colposcopy in women referred with low-grade cervical cytology? A prospective cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mette Mindedahl Jespersen ◽  
Berit Bargum Booth ◽  
Lone Kjeld Petersen
Keyword(s):  
Cervical Cancer ◽  
Cohort Study ◽  
Cancer Screening ◽  
Intraepithelial Neoplasia ◽  
Relative Increase ◽  
Low Grade ◽  
Squamocolumnar Junction ◽  
Study Participants ◽  
Cytology Screening

Abstract Background Controversy surrounds whether women with low-risk cytology screening results but a normal colposcopic assessment should have random biopsies taken. The aim of this study was to determine the yield of CIN2+ from one to four cervical biopsies in women with cytology of LSIL or ASCUS and a normal colposcopic impression. Methods Between January 2017 and September 2020, women over 18 years old referred for colposcopic examination due to either an abnormal smear (ASCUS+) or follow-up after previous cervical intraepithelial neoplasia (CIN) were invited to participate in the study. All study participants underwent colposcopic examination and had four biopsies taken. The biopsies were analyzed separately. Results In total, 1327 women with abnormal cervical cancer screening results or attending follow-up after a previous CIN diagnosis were enrolled in the study and examined by colposcopy. Of these, 173 were newly referred with cytology of LSIL or ASCUS and had a normal colposcopic impression and four adequate biopsies. Of these, 22.0% were diagnosed with CIN2+. When combining the results of the four biopsies, we found a 100% relative increase in CIN2+ cases compared to using only one biopsy (from 11.0% to 22.0%, P = 0.006). Conclusion As we found CIN2+ from random cervical biopsies in 22.0% of women with cytology of LSIL or ASCUS who had a normal colposcopic impression, we advocate performing four random cervical biopsies at the squamocolumnar junction in such women. Trial registration NCT04249856, January 31 2020 (retrospectively registered).

P3746Temporal patterns of premature atrial contractions predict atrial fibrillation occurrence in bradycardia patients continuously monitored through pacemaker diagnostics

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
G Boriani ◽  
G L Botto ◽  
P Pieragnoli ◽  
R P Ricci ◽  
M Biffi ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Continuous Monitoring ◽  
Cox Model ◽  
National Registry ◽  
Relative Increase ◽  
Adverse Outcomes ◽  
Temporal Occurrence ◽  
Observation Period ◽  
Atrial Rhythm

Abstract Background The frequency of premature atrial complexes (PACs) has been indirectly related with atrial fibrillation (AF) occurrence and adverse outcomes. Objective To evaluate whether temporal patterns of PACs are directly associated with AF onset in pacemaker patients with continuous monitoring of the atrial rhythm. Methods Overall, 193 pacemaker patients (49% female, 72±9 years old), enrolled in a national registry, were analyzed. Frequency of daily PACs was measured in a 14-day initial observation period, during which patients were in sinus rhythm. In the following period, temporal occurrence and frequency of daily PACs and eventual onset of AF were derived by pacemaker diagnostics. Results In the run-in period, median PACs frequency was 614 PACs/day (interquartile range=70–3056). Subsequently, in a median follow-up of 6 months, AF occurred in 109 patients, in particular in 37/96 (38.5%) patients with a PAC rate<614 PACs/day and in 72/97 (74.2%) patients with PAC rate≥614 PACs/day (p<0.001). In patients with AF occurrence, the number of daily PACs, normalized by dividing for the average of PACs in 10 preceding days, progressively increased in the 5–6 days preceding AF (Figure). Cox Model predictive analysis showed that the risk of AF was significantly higher in patients with a relative increase of the daily PACs higher than 30% compared with PACs average number in 10 preceding days (hazard ratio (95% confidence interval) = 3.67 (2.40–5.59), p<0.001). PACs changes daily trend before AF Conclusion PACs frequency increases in the 5–6 days preceding AF onset. A relative increase of the daily PACs is significantly associated with the risk of AF occurrence.

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