Effects of physical conditioning on lipids and arachidonic acid metabolites in untrained boys: a longitudinal study

2006 ◽  
Vol 31 (4) ◽  
pp. 432-441 ◽  
Author(s):  
Apostolos Thomas Stergioulas ◽  
Dimitrios Konstantinos Filippou

In addition to a variety of lipids, 2 products of the arachidonic acid cascade, prostacyclin and thromboxane, are involved in the pathogenesis of atherosclerosis as a result of their effects on platelet function and on the vascular endothelium. The aim of the present investigation was to ascertain if a sub-maximal 8 week endurance training period followed by a 4 week detraining period would have any effects on high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC), triglycerides (TG), 2,3-dinor-6-keto-prostaglandin F1α(2,3-dinor-6-keto-PGF1α), the urinary metabolite of prostacyclin, 2,3-dinor-thromboxane B2(2,3-dinor-TXB2), the urinary metabolite of thromboxane, and the ratios of TC to HDL-C and of 2,3 dinor-6-keto-PGF1αto 2,3-dinor-TXB2. Thirty-eight boys aged 10–14 were randomly divided into exercise (n = 21) and control (n = 17) groups. The exercise group trained on a bicycle ergometer 4 times/week, 1 h/session, at 80% of their physical working capacity at a heart rate of 170 beats/min (PWC170), for 8 weeks. The control group did not participate in any specific physical exercise program. The results showed that relative to the control group, the exercise group had a significant increase in HDL-C and 2,3-dinor-6-keto-PGF1αconcentrations at the end of the 4th (p < 0.05 and p < 0.001, respectively) and the 8th week (p < 0.01 and p < 0.001) of training, respectively; a significant increase in the 2,3 dinor-6-keto-PGF1α– 2,3-dinor-TXB2ratio (p < 0.05 and p < 0.01 at the same intervals); a significant decrease in TG at the end of the 8th week of training (p < 0.05); and a significant decrease in the TC–HDL-C ratio at the end of the 4th (p < 0.05) and 8th weeks of training (p < 0.001).

2012 ◽  
Vol 1 (6) ◽  
pp. 292-297
Author(s):  
Eizadi Mojtaba ◽  
Kohandel Mahdi ◽  
Kasbparast JR Mehdi ◽  
Sarshin Amir

The adipocyte‐derived hormones leptin is known to increase in obesity and related disease. Thirty two non‐trained males (39±4.32 years, 176.5 – 6.5 ± 6.42 cm, and 31 ± 3.14 body fat %) were matched according to physical fitness enrolled in this study and divided to exercise and control group by accidentally. The participants of exercise group were completed an aerobic exercise program for 3 months (3 days/weekly) and control group were barred of exercise in this period. Anthropometrical measurements and fasting blood samples were obtained before and after interventions in two groups. Blood samples were collected in order to measuring serum leptin, triglyceride (TG), high density lipoprotein cholesterol (HDL), and Low density lipoprotein cholesterol (LDL). Pre‐ and post exercise independent variables were compared using a paired‐samples t‐test. Compared to pre‐training, the leptin levels decreased significantly (P<0.01) after aerobic exercise program in exercise group but not in the control subjects. Triglyceride concentration was decreased with exercise training whereas concentrations of LDL cholesterol did not change in exercise group (p≥0.05). Exercise training resulted in significant decrease in anthropometrical indexes (p Ë‚ 0.05) and a borderline significant increase in HDL (p=0.052). TG/HDL ratio were significantly decreased in exercise group by exercise training (p=0.028). All variable in control group remained no change in control group (p ≥ 0.05). These data suggest, despite lack significant changes in some lipid profile markers, aerobic exercise program can be improve systemic inflammation and TG/HDL ratio as a cardiovascular risk factor in obese subjects.


2017 ◽  
Vol 43 (1) ◽  
pp. 40-48
Author(s):  
Veysi Çay ◽  
Gurbuz Buyukyazi ◽  
Cevval Ulman ◽  
Fatma Taneli ◽  
Yeliz Doğru ◽  
...  

AbstractObjectives:This study aims to examine effects of aerobic jogging and explosive power exercises on body composition, maximal oxygen consumption (MaxVOMaterials and methods:Thirty seven healthy males were divided into exercise group (EG, n=19) and control group (CG, n=18). EG completed 10 weeks of outdoor aerobic (jogging at 60–70% maximal heart rate reserve starting from 20 min steadily increasing up to 28 min) and explosive power exercises (in 2–3 sets, with maximum repetitions lasting 15 s), 3 times per week. All measurements were taken before and after the exercise program. BMD was measured via dual energy X-ray absorptiometry (DEXA).Results:Body mass index (p<0.001) significantly decreased; MaxVOConclusion:Performing our outdoor exercise program in spring months might have an important role in the significant increase (9 vs. 22 ng/mL) in mean vitamin D level, which reached above the fracture risk level of 20 ng/mL.


2017 ◽  
Vol 5 (4) ◽  
pp. 74
Author(s):  
Nevzat Demirci ◽  
Mehmet Akif Ziyagil

The metabolic fitness (MF) is a component of athletes’ physical conditioning. This study aims to investigate the effects of quercetin supplementation on Turkish Junior athletes’ lipid and protein metabolism relating to MF after one month classic boxing training. Totally 20 voluntary junior male athletes were separated into two equal groups as the experimental group (EG) and control group (CG). The participants were supplemented with 500 mg quercetin fifteen minutes before each workout in one month boxing training program. Blood samples during pre and post training were taken from athletes in order to determine metabolic fitness related parameters. Lipid profile contains low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), trigliserid (TG), total cholesterol (TC) variables while protein metabolism includes the albumin, total protein, direct bilirubin and total bilirubin parameters. The Mann Whitney U analyzes were used for comparison of the means between experimental and control groups during pre and posttest and between pre and post test results in experimental and control groups. This study showed that EG had a similar physical characteristic with CG. There were significant decrease in TC and LDL-C and an increase in HDL-C in EG while there was only significant increase in HDL-C of in controls. A significant difference of HDL-C was observed between EG and CG during pretest. In other side, TC and LDL-C and HDL-C were significantly differentiated between EG and CG during posttest. Conclusion: it can be concluded that quercetin plays an important role on lipid metabolism not protein.


2017 ◽  
Vol 23 (2) ◽  
pp. 133-136
Author(s):  
Bruna Camilo Turi ◽  
Mariana Rotta Bonfim ◽  
Jamile Sanches Codogno ◽  
Rômulo Araújo Fernandes ◽  
Lia Grego Muniz de Araújo ◽  
...  

ABSTRACT Introduction: In the last decades, unhealthy habits, such as low levels of physical activity and poor diet, have increased. Consequently, the prevalence of cardiovascular diseases and mortality has increased significantly among adults. However, it is known that regular physical exercises help to improve health outcomes. Thus, the aim of this study was to analyze the effects of eight years of regular participation in an exercise program on blood pressure and mortality in the Brazilian public health system. Methods: The sample consisted of 34 participants with hypertension and/or type II diabetes who were followed up for eight years. They were paired by age, body mass index and chronic disease in two groups: exercise and control. During the follow-up period, medical records were used to assess systolic and diastolic blood pressure, as well as number of medical appointments and the occurrence of deaths. Results: In the follow-up period, five participants died in the control group and none in the exercise group. The Kaplan-Meier analysis identified 29.4% lower mortality among active participants (Fisher's exact test with p = 0.044). The number of medical appointments and the values of diastolic blood pressure were significantly lower for active participants. Conclusion: After a follow-up of eight years, participants in the exercise group attended fewer medical appointments, had better blood pressure control and a lower occurrence of deaths.


Author(s):  
Dilton Dos Santos Silva ◽  
Felipe José Aidar Martins ◽  
Dihogo Gama de Matos ◽  
Raphael Fabrício De Souza ◽  
Osvaldo Costa Moreira ◽  
...  

Objective: Analyze the effects of a physical exercise program on blood markers and sleep quality in the elderly. Method: A total of 112 elderly people with metabolic diseases controlled by hypocholesterolemic and hypoglycemic medications participated in the study. The participants were divided into two groups, an exercise group composed of 54 individuals with a mean age of 62 years and control group of 58 individuals with a mean age of 63 years. Results: Blood glucose, total cholesterol, and triglyceride levels showed a mean reduction of 27.47, 18.13, and 23.48 mg/dl, respectively, and an increase of 8.98 mg/dl in the high-density lipoprotein level was seen. A significant change was seen in the low-density lipoprotein, very-low-density lipoprotein, and calcium levels on comparing the exercise group post-test values with that of the control group pre-test. The Pittsburgh Sleep Quality Index score showed a significant reduction of 3.15 (p < 0.001, μp2=0.78) on comparing the exercise group with the control group. Conclusion: It can be concluded that the physical exercise program, consisting of supervised walking and gymnastics with localized quadriceps muscle strengthening exercises, performed for 16 weeks at a frequency of three times a week for 60 min, was effective in improving the low-density lipoprotein and very-low-density lipoprotein levels and sleep quality of the elderly.


2018 ◽  
Vol 32 (1) ◽  
pp. 74-81
Author(s):  
Sukanya Chongthawonsatid ◽  
Wipawee Chinjenpradit

Purpose Exercise training has been shown to be an effective and integral component of non-pharmacological intervention for the control of blood pressure. The purpose of this paper is to compare the effectiveness of a supervised modified exercise program of moderate-intensity exercise for one hour per week including the use of a pedometer, and with the use of a pedometer alone without additional exercise in reducing blood pressure. Design/methodology/approach The study was a randomized control trial, with an experimental group of 30 people and a control group of 26 people. Participants were males and females aged 30-65 years with pre- to mild hypertension, and who were not receiving any drugs for the treatment of hypertension. Participants of the experimental group were assigned to a fitness program with supervised exercise once a week at the Golden Jubilee Medical Fitness Center, given access to a pedometer, and provided with health education. Participants in the control group were assigned to use a pedometer only. All experimental and control group members participated in the study for three months, as well as a follow-up at the third and sixth month. Findings Comparison of the experimental and control groups at the first, third, and sixth month, using repeated measures analysis found that interaction effect groups and times were significantly different for mean systolic blood pressure (SBP), body mass index (BMI), hip circumference (HC), and high-density lipoprotein (HDL) (p<0.05). Mean SBP, diastolic blood pressure (DBP), BMI, waist circumference (WC), HC, and low-density lipoprotein (LDL) within groups were significantly different (p<0.05). Mean WC, cholesterol, LDL, and triglyceride between groups were significantly different (p<0.05). Both groups had SBP improved at the third and sixth month when compared with baseline data. Mean HDL increased in the experimental group and decreased in the control group. Multiple regression analysis showed that both groups were not statistically different after intervention, SBP was reduced in the experimental group when compared to the control group. However, at six months, members in the experimental group reported spending less time sitting or reclining on a typical day than members of the control group. Originality/value A supervised one-time per week fitness program combined with pedometer and pedometer alone were not different in reducing blood pressure, as both groups showed decreases in blood pressure. However, the group with the supervised exercise program tended to change sedentary behaviors in the longer term compared to those who used the pedometer alone.


2020 ◽  
Vol 19 (2) ◽  
pp. 82
Author(s):  
Eduardo Federighi Baisi Chagas ◽  
Angélica Cristiane Cruz ◽  
Pedro Henrique Rodrigues ◽  
Cristiano Sales Silva ◽  
Robison José Quitério

Objective: Investigating the effect of 12 weeks of an aquatic exercise program on cardiac autonomic modulation by heart rate variability index of postmenopausal women with type 2 diabetes mellitus (T2DM). Methods: A randomized clinical trial was performed in 25 women aged 51 to 83 years, divided into exercise group (EG) (n = 13) submitted for 12 weeks to two weekly sessions of 50 minutes each, and control group (CG) (n = 12) without exercise. Results: Regarding cardiac autonomic modulation significant interaction was observed for TINN values (ms), indicating a slight increase in EG, but mostly a reduction in CG. The regression analysis also pointed effect of aquatic exercise on reducing the LF/HF ratio, after controlling for covariates diastolic blood pressure and dyslipidemia. Conclusion: The aquatic exercise had a significant effect on the reduction of cardiovascular risk, mainly in relation to glycemia and abdominal obesity, which may represent a protective effect of exercise in the progression of autonomic dysfunction, but its effect on autonomic modulation seems to depend on a greater volume and time with aquatic exercise.Keywords: diabetes, women, menopause, autonomic nervous system.


2014 ◽  
Vol 2 (11_suppl3) ◽  
pp. 2325967114S0028
Author(s):  
Şeyda Toprak Çelenay ◽  
Derya Özer Kaya

Objectives: The study aimed to investigate effects of thoracic stabilization exercises on postural back pain, spinal alignment and inclination in university students who had postural back pain. Methods: University students who had minor to moderate postural back pain (18-25 years) were randomly allocated into Exercise (n = 28) and Control (n = 25) Groups. The programs were carried out 8 weeks and 3 days/week. The postural back pain intensity was assessed by Visual Analogue Scale. Spinal alignment and spinal inclination were evaluated with the Spinal Mouse® (Idiag, Fehraltorf, Switzerland). Assessments were applied before (BP) and after program (AP). Wilcoxon and Mann Whitney U tests were utilized. Results: The significant differences were observed for postural back pain (BP: 1.33 (1.16); AP: 0.33 (1.16)), thoracic curvature (BP: 44.50 (11.75); AP: 36.50 (13.25)), lumbar curvature (BP: -29.00 (10.00); AP: -7.00 (19.50)) and spinal inclination (BP: 5.00 (5.25); AP: 0.00 (4.00)) in Exercise Group between BP and AP (p<0.05). No significant differences were observed in Control group for all the parameters (p>0.05). The intergroup comparison showed that postural back pain, thoracic curvature, lumbar curvature and spinal inclination decreased in Exercise Group in comparison to Control Group (p<0.05). Conclusion: The exercise program with eight weeks regular practice was effective on improving postural back pain, spinal alignment and inclination in university students with postural back pain.


2018 ◽  
Vol 31 (1) ◽  
pp. 25-33
Author(s):  
Ozanildo Vilaça do NASCIMENTO ◽  
Ana Paula de Araújo BOLETI ◽  
Maíra SCHWERTZ ◽  
Emerson Silva LIMA

ABSTRACT Objective The goal of this study were to investigate the effects of continuous exercise with/or without the ingestion the Camu-camu pulp in a rat model of obesity. Methods Neonate male Wistar rats, receiving monosodium glutamate, subcutaneously were separated into foour groups: sedentary group S (no treatment), exercise group E (continuous swimming training), Camu-camu group C (25mL of pulp of Camu-camu/day) and exercise and Camu-camu group EC (25mL of pulp of Camu-camu/day, continuous swimming). After 12 weeks, the animals were received euthanasia. Results The exercise program was conducted for five days for 12 weeks and the effects of supplementation with or without Camu-camu in obese rats were analyzed, showing that the relative levels of the variables cholesterol, triglycerides, glucose, High Density Lipoprotein and Low Density Lipoprotein and in all groups there was a significant reduction (.<0.001), except for the control group. Body weight and feed intake, epididymal and visceral fat deposits were not significantly different between the means of groups C and E, but these groups showed a significant difference when compared to the EC group (.<0.001). Conclusion The results demonstrate the effectiveness of continuous exercise and diet supplemented with Camu-camu fruit pulp to control obesity.


2020 ◽  
Vol 5 (1) ◽  
pp. 9-15
Author(s):  
Maryam Farbod ◽  
Mojtaba Eizadi ◽  
Mohammad Rashidi ◽  
Zahra Mirakhori

Introduction: Obesity is a major risk factor for inflammation and cardiovascular diseases. We tried to assess whether 12 weeks of aerobic exercises affect serum resistin level and lipid profile in overweight females or not. Methods: For this purpose, 32 non-trained adult females with the mean age of 38 ± 7 years old and body mass index (BMI) of 32 ± 3 kg/m2 were randomly assigned to aerobic exercise (n=16) and control (n=16) groups. Twelve weeks of aerobic exercise program including 3 sessions weekly at 60-75% of maximum heart rate was considered. Fasting serum resistin level, lipid profile (total cholesterol [TC], low-density lipoprotein [LDL] and high-density lipoprotein [HDL] cholesterol, and triglyceride [TG]), and anthropometric indexes were measured and compared between the two groups before and after training. Results: Serum resistin, lipid profile markers, and anthropometrical indexes were not significantly different at baseline between the two groups (P>0.05). TG, TC, LDL, and serum resistin did not change significantly after the intervention in the exercise group (P>0.05). However, a significant increase in HDL (exercise: 46.3 ± 9.6 vs. 51.4 ± 8.5, P=0.011; control: 45.8 ± 7.9 vs. 46.8 ± 6.9 P=0.326) and a significant decrease in LDL/HDL ratio (exercise: 2.94 ± 0.12 vs. 2.47 ± 0.19, P=0.019; control: 3.14 ± 0.23 vs. 3.18 ± 0.63, P=0.265) were observed after the intervention. Other variables in the control group remained unchanged. Conclusion: Aerobic exercises had no impacts on the inflammatory profile but could improve lipid profile with an emphasis on HDL in adult obese women.


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