scholarly journals Evaluation of a program of physical exercise on blood markers and sleep quality in elderly

Author(s):  
Dilton Dos Santos Silva ◽  
Felipe José Aidar Martins ◽  
Dihogo Gama de Matos ◽  
Raphael Fabrício De Souza ◽  
Osvaldo Costa Moreira ◽  
...  

Objective: Analyze the effects of a physical exercise program on blood markers and sleep quality in the elderly. Method: A total of 112 elderly people with metabolic diseases controlled by hypocholesterolemic and hypoglycemic medications participated in the study. The participants were divided into two groups, an exercise group composed of 54 individuals with a mean age of 62 years and control group of 58 individuals with a mean age of 63 years. Results: Blood glucose, total cholesterol, and triglyceride levels showed a mean reduction of 27.47, 18.13, and 23.48 mg/dl, respectively, and an increase of 8.98 mg/dl in the high-density lipoprotein level was seen. A significant change was seen in the low-density lipoprotein, very-low-density lipoprotein, and calcium levels on comparing the exercise group post-test values with that of the control group pre-test. The Pittsburgh Sleep Quality Index score showed a significant reduction of 3.15 (p < 0.001, μp2=0.78) on comparing the exercise group with the control group. Conclusion: It can be concluded that the physical exercise program, consisting of supervised walking and gymnastics with localized quadriceps muscle strengthening exercises, performed for 16 weeks at a frequency of three times a week for 60 min, was effective in improving the low-density lipoprotein and very-low-density lipoprotein levels and sleep quality of the elderly.

Author(s):  
Eman A. Al-Rekabi ◽  
Dheyaa K. Alomer ◽  
Rana Talib Al-Muswie ◽  
Khalid G. Al-Fartosi

The present study aimed to investigate the effect of turmeric and ginger on lipid profile of male rats exposed to oxidative stress induced by hydrogen peroxide H2O2 at a concentration of 1% given with consumed drinking water to male rats. Methods: 200 mg/kg from turmeric and ginger were used, and the animals were treatment for 30 days. Results: the results showed a significant increase in cholesterol, triglycerides, low density lipoprotein (LDL), very low density lipoprotein (VLDL), whereas it explained a significant decrease in high density lipoprotein (HDL) of male rats exposed to oxidative stress when compared with control group. the results showed a significant decrease in cholesterol, triglycerides, (LDL), (VLDL), whereas it explained a significant increase in (HDL) of rats treated with turmeric and ginger at dose 200 mg/kg when compared with male rats exposed to oxidative stress.


2021 ◽  
Vol 34 (1) ◽  
pp. 139-146
Author(s):  
Elham K. Nasser ◽  
Kithar R. Majeed ◽  
Hayder I. Ali

Fortified milk containing Lactobacillus plantarum, L. casei, and L. acidophilus isolates and their mixture were used in dosing the male albino rats at an age of 9-12 weeks at an average of 23 g with induced hypothyroidism at a concentration of 0.6 g.kg-1 of carbimazole. Total cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very-low-density lipoprotein (VLDL) were estimated. The results showed a significant increase in the level of triglycerides (TG), cholesterol and triglycerides. Low-density lipoprotein (LDL) and very-low-density lipoprotein (VLDL), with a significant decrease in the level of high-density lipoprotein (HDL) in infected male mice, compared to the control sample, and upon dosing with liquid milk fortified, it returned to its normal level without significant differences from the control group.


Background and Aims: The present study aimed to compare the effects of three therapeutic methods (including herbal, atorvastatin, and exercise) on liver enzymes and lipid profiles in hypercholesterolemic rats. Materials and Methods: A number of 32 male Wistar rats were randomly assigned to four groups (n=8), including hypercholesterolemia (Hc) control group, anvil extract at a dose of 100 mg/kg, (Ext), exercise (E), and atorvastatin (AT) at a dose 10 mg/kg. Endurance training, anvil extract, and atorvastatin were performed three sessions per week for 8 weeks. Thereafter, liver biochemical tests, including alkaline phosphatase (ALT), aspartate aminotransferase (AST), and lipid profiles were performed using a biochemical autoanalyzer (Ra-2000 made in USA) and the kits provided by Pars Azmun company. The data were analyzed in SPSS software using analysis of variance (ANOVA) and Tukeychr('39')s test were used for data analysis. Results: The results of statistical analysis indicated that all variables (e.g., Alanine transaminase, Triglyceride, High-density lipoprotein (HDL), low-density lipoprotein (LDL), and very-low-density lipoprotein (VLDL), except for ALT, AST, and cholesterol, were significant in all groups. The results of the statistical analysis demonstrated that triglycerides and VLDL significantly reduced in the atorvastatin and exercise groups, compared to the hypercholesterolemic control group. Furthermore, HDL had a significant increase in the exercise group, compared to the atorvastatin, extract, and control groups. In addition, LDL significantly decreased in the exercise group, compared to the atorvastatin group. Conclusion: The results of the current study pointed to the similar effects of medication and exercise on the improvement of some lipid profiles. Nonetheless, exercise is advantageous over the use of medicine and herbal extracts due to the positive effects of exercise on the reduction of blood lipids and the absence of any side effects.


2021 ◽  
Vol 49 (4) ◽  
pp. 030006052110026
Author(s):  
Jun Zhao ◽  
Yubo Ma ◽  
Xiaoqiang Zhai ◽  
Hecheng Li ◽  
Ziming Wang ◽  
...  

Objective To investigate sex hormone and blood lipid levels in patients with lifelong premature ejaculation (LPE) in China. Methods Sex hormone and blood lipid levels were measured in 156 patients with LPE and 76 healthy controls. The Premature Ejaculation Diagnostic Tool (PEDT) and Chinese Index of Sexual Function for Premature Ejaculation-5 Questionnaires (CIPE-5) were applied to diagnose and grade LPE. Results PEDT and CIPE-5 scores were significantly altered in the LPE group compared with the control group. Free testosterone levels were significantly higher in the LPE group than in the control group. Free testosterone levels were also significantly higher in the mild, moderate, and severe LPE subgroups than in the control group. Total testosterone and prolactin levels tended to be lower in the control group than in the LPE group. Very low-density lipoprotein levels were significantly lower in the LPE group and LPE subgroups than in the control group. Triglyceride levels were highest in controls and decreased with progression of LPE. Conclusions Patients with LPE have higher free testosterone levels and lower very low-density lipoprotein levels than controls. These findings indicate that these factors might be indices for LPE. However, the reasons for these phenomena need to be further investigated.


2012 ◽  
Vol 36 (0A) ◽  
pp. 181-186
Author(s):  
Suad A. Jashamy

A total of 15 Turkish- Awassi rams at ages ranged 2 - 2.5 years, and their weight rangedbetween 79.5 – 80.3 kg, Rams were randomly divided into 3 equal groups of 5 rams eachgroup. The first group were taken1000 while the second group were taken 2000 gaussmagnetic water, the third group were taken normal streaming water which is considered as a(control group). Blood sample were taken at the beginning of the experiment, and repeatedevery two weeks during the experimental period (four months). Results revealed that treatedthe rams with magnetically treated water resulted in significantly decreased (p<0.01) incholesterol (1.78-4.08), triglycerides (0.94-0.054), low density lipoprotein (LDL) (1.4-0.2),Very low density lipoprotein (VLDL) (1.87-0.14) and significant increase (p<0.01) in highdensity lipoprotein (HDL)(0.17-0.49) .It could be concluded that rams received magneticallytreated water resulted in significant improvement in level of lipid involved in this experiment.


1984 ◽  
Vol 246 (2) ◽  
pp. E187-E192 ◽  
Author(s):  
G. Steiner ◽  
F. J. Haynes ◽  
G. Yoshino ◽  
M. Vranic

The effect of hyperinsulinemia (2 wk of twice daily NPH insulin) on the kinetics of very-low-density lipoprotein (VLDL)-triglyceride (TG) was studied in rats. To avoid profound hypoglycemia the rats were allowed sucrose ad libitum. Two control groups were needed: chow only and ad libitum sucrose-supplemented (high-CHO). The insulin-treated rats had 15 times higher IRI and 50% lower plasma glucose levels than either control group. Their TG production exceeded and their TG concentrations were less than those of either control group. This indicated that their TG removal was increased even more than their TG production. This increase in TG production occurred despite lower plasma free fatty acid (FFA) levels, suggesting that a greater proportion of TG fatty acids came from a source other than FFA. Compared with chow controls, high-CHO controls had the same peripheral IRI, a slight increase in TG production, and an increase in TG concentration. The differences between the effects of CHO supplementation alone or together with injected insulin may relate to the IRI and/or the route of access of insulin (peripheral vs. portal). The present studies indicate that hyperinsulinemia, either directly or indirectly, accelerates triglyceride turnover.


2020 ◽  
Vol 27 (02) ◽  
pp. 230-236 ◽  
Author(s):  
Shazia Bano ◽  
Syed Munawar Alam ◽  
Saima Iram

Objectives: To observe the association between dyslipidemia and homocysteine level in epileptic patients; especially on carbamazepine monotherapy. Study Design: Cross sectional study. Setting: Neurology Department and Epilepsy Centre of Jinnah Post Graduate Medical Centre, Karachi. Period: From January 2015 – January 2016. Material & Methods: Total 300 subjects, aged more than 15 years were included and divided into three groups.  Group A (100 healthy individuals) was control group, Group B (100 newly diagnosed epileptic patients without antiepileptic therapy), Group C (100 epileptic patients on Carbamazepine therapy, which was further subdivided into C-I (n=33) had epileptic patients on Carbamazepine therapy less than 1 year, C-II (n=33) comprised of epileptic patients on Carbamazepine therapy 1-2 years and C-III (n=33) had epileptic patients on Carbamazepine therapy more than 2 years. Serum lipid profile and homocysteine levels were measured. Results: In patients with different durations of carbamazepine monotherapy; a noteworthy incremental trend in the levels of homocysteine, total cholesterol, triglyceride, low density lipoprotein cholesterol, very low density lipoprotein cholesterol was observed. Homocysteine was found positively correlated with total cholesterol, triglyceride, low density lipoprotein cholesterol, very low density lipoprotein cholesterol. Conclusion: In our study dyslipidemia was associated with hyperhomocysteinemia, which in turn was correlated with atherosclerosis in CBZ treated epileptic patients.


2020 ◽  
Vol 27 (02) ◽  
pp. 230-236
Author(s):  
Shazia Bano ◽  
Syed Munawar Alam ◽  
Saima Iram

Objectives: To observe the association between dyslipidemia and homocysteine level in epileptic patients; especially on carbamazepine monotherapy. Study Design: Cross sectional study. Setting: Neurology Department and Epilepsy Centre of Jinnah Post Graduate Medical Centre, Karachi. Period: From January 2015 – January 2016. Material & Methods: Total 300 subjects, aged more than 15 years were included and divided into three groups.  Group A (100 healthy individuals) was control group, Group B (100 newly diagnosed epileptic patients without antiepileptic therapy), Group C (100 epileptic patients on Carbamazepine therapy, which was further subdivided into C-I (n=33) had epileptic patients on Carbamazepine therapy less than 1 year, C-II (n=33) comprised of epileptic patients on Carbamazepine therapy 1-2 years and C-III (n=33) had epileptic patients on Carbamazepine therapy more than 2 years. Serum lipid profile and homocysteine levels were measured. Results: In patients with different durations of carbamazepine monotherapy; a noteworthy incremental trend in the levels of homocysteine, total cholesterol, triglyceride, low density lipoprotein cholesterol, very low density lipoprotein cholesterol was observed. Homocysteine was found positively correlated with total cholesterol, triglyceride, low density lipoprotein cholesterol, very low density lipoprotein cholesterol. Conclusion: In our study dyslipidemia was associated with hyperhomocysteinemia, which in turn was correlated with atherosclerosis in CBZ treated epileptic patients.


2018 ◽  
Vol 31 (1) ◽  
pp. 25-33
Author(s):  
Ozanildo Vilaça do NASCIMENTO ◽  
Ana Paula de Araújo BOLETI ◽  
Maíra SCHWERTZ ◽  
Emerson Silva LIMA

ABSTRACT Objective The goal of this study were to investigate the effects of continuous exercise with/or without the ingestion the Camu-camu pulp in a rat model of obesity. Methods Neonate male Wistar rats, receiving monosodium glutamate, subcutaneously were separated into foour groups: sedentary group S (no treatment), exercise group E (continuous swimming training), Camu-camu group C (25mL of pulp of Camu-camu/day) and exercise and Camu-camu group EC (25mL of pulp of Camu-camu/day, continuous swimming). After 12 weeks, the animals were received euthanasia. Results The exercise program was conducted for five days for 12 weeks and the effects of supplementation with or without Camu-camu in obese rats were analyzed, showing that the relative levels of the variables cholesterol, triglycerides, glucose, High Density Lipoprotein and Low Density Lipoprotein and in all groups there was a significant reduction (.<0.001), except for the control group. Body weight and feed intake, epididymal and visceral fat deposits were not significantly different between the means of groups C and E, but these groups showed a significant difference when compared to the EC group (.<0.001). Conclusion The results demonstrate the effectiveness of continuous exercise and diet supplemented with Camu-camu fruit pulp to control obesity.


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