MICROSCOPIC PROPERTIES OF BONE TISSUE USING MEASUREMENT SYSTEM WITH NANO-RESOLUTION
To understand the physiology and pathology of human skeletal system, the accurate measurement of microscopic biomechanical properties of bone is an important works. In this study, a measurement system of the Poisson's ratio with a sub-nano resolution was developed. The resulting resolution of the system was 0.3 nm, which was 0.1% of the measurement error for this system configuration. Using this measurement system, actual tests were performed to check the capability of the measurement system. Cubic bone specimens with a dimension of 300 μm were loaded up to an axial strain of 0.5%, which is within the elastic range of the specimens. The mean elastic modulus and the Poisson's ratio of bovine femoral cortical bone measured in this study were 14.42 GPa ( SD ± 0.6179) and 0.265 ( SD ± 0.0125) respectively. The developed system will be useful to understand the biomechanics of bones for modeling the mechanobiological bone system.