scholarly journals Suicide in African American Adolescents: Understanding Risk by Studying Resilience

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
W. LaVome Robinson ◽  
Christopher R. Whipple ◽  
Kate Keenan ◽  
Caleb E. Flack ◽  
LaRicka Wingate
Keyword(s):  
African American ◽  
Youth Development ◽  
Suicide Risk ◽  
African American Adolescents ◽  
Current Status ◽  
Annual Review ◽  
Publication Date ◽  
Risk And Resilience ◽  
Effective Prevention ◽  
Suicide Rates

Historically, suicide rates for African American adolescents have been low,relative to rates for youth of other racial-ethnic backgrounds. Since 2001, however, suicide rates among African American adolescents have escalated: Suicide is now the third leading cause of death for African American adolescents. This disturbing trend warrants focused research on suicide etiology and manifestation in African American adolescents, along with culturally sensitive and effective prevention efforts. First, we revisit leading suicide theories and their relevance for African American adolescents. Next, we discuss health promotive and protective factors within the context of African American youth development. We also critique the current status of suicide risk assessment and prevention for African American adolescents. Then, we present a heuristic model of suicide risk and resilience for African American adolescents that considers their development within a hegemonic society. Finally, we recommend future directions for African American adolescent suicidology. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 18 is May 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

The Recent Rise of Suicide Mortality in the United States

2021 ◽  
Vol 43 (1) ◽  
Author(s):  
Gonzalo Martínez-Alés ◽  
Tammy Jiang ◽  
Katherine M. Keyes ◽  
Jaimie L. Gradus
Keyword(s):  
Public Health ◽  
United States ◽  
Suicide Risk ◽  
The United States ◽  
Health Concern ◽  
Suicide Mortality ◽  
Annual Review ◽  
Publication Date ◽  
Suicide Rates ◽  
Subsequent Decrease

Suicide is a major public health concern in the United States. Between 2000 and 2018, US suicide rates increased by 35%, contributing to the stagnation and subsequent decrease in US life expectancy. During 2019, suicide declined modestly, mostly owing to slight reductions in suicides among Whites. Suicide rates, however, continued to increase or remained stable among all other racial/ethnic groups, and little is known about recent suicide trends among other vulnerable groups. This article ( a) summarizes US suicide mortality trends over the twentieth and early twenty-first centuries, ( b) reviews potential group-level causes of increased suicide risk among subpopulations characterized by markers of vulnerability to suicide, and ( c) advocates for combining recent advances in population-based suicide prevention with a socially conscious perspective that captures the social, economic, and political contexts in which suicide risk unfolds over the life course of vulnerable individuals. Expected final online publication date for the Annual Review of Public Health, Volume 43 is April 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Brain-Protective Mechanisms of Transcription Factor NRF2: Toward a Common Strategy for Neurodegenerative Diseases

2021 ◽  
Vol 62 (1) ◽  
Author(s):  
Antonio Cuadrado
Keyword(s):  
Transcription Factor ◽  
Neurodegenerative Diseases ◽  
Brain Cell ◽  
Current Status ◽  
Annual Review ◽  
Publication Date ◽  
Related Factor ◽  
Protective Mechanisms ◽  
Cell Functions ◽  
Pass Through

Neurodegenerative diseases are characterized by the loss of homeostatic functions that control redox and energy metabolism, neuroinflammation, and proteostasis. The transcription factor nuclear factor erythroid 2–related factor 2 (NRF2) is a master controller of these functions, and its overall activity is compromised during aging and in these diseases. However, NRF2 can be activated pharmacologically and is now being considered a common therapeutic target. Many gaps still exist in our knowledge of the specific role that NRF2 plays in specialized brain cell functions or how these cells respond to the hallmarks of these diseases. This review discusses the relevance of NRF2 to several hallmark features of neurodegenerative diseases and the current status of pharmacological activators that might pass through the blood-brain barrier and provide a disease-modifying effect. Expected final online publication date for the Annual Review of Pharmacology and Toxicology, Volume 62 is January 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Small RNAs in Plant Immunity and Virulence of Filamentous Pathogens

2021 ◽  
Vol 59 (1) ◽  
Author(s):  
Yongli Qiao ◽  
Rui Xia ◽  
Jixian Zhai ◽  
Yingnan Hou ◽  
Li Feng ◽  
...  
Keyword(s):  
Gene Silencing ◽  
Small Rna ◽  
Small Rnas ◽  
Plant Immunity ◽  
Receptor Gene ◽  
Current Status ◽  
Annual Review ◽  
Publication Date ◽  
Small Interfering Rnas ◽  
Host Pathogen

Gene silencing guided by small RNAs governs a broad range of cellular processes in eukaryotes. Small RNAs are important components of plant immunity because they contribute to pathogen-triggered transcription reprogramming and directly target pathogen RNAs. Recent research suggests that silencing of pathogen genes by plant small RNAs occurs not only during viral infection but also in nonviral pathogens through a process termed host-induced gene silencing, which involves trans-species small RNA trafficking. Similarly, small RNAs are also produced by eukaryotic pathogens and regulate virulence. This review summarizes the small RNA pathways in both plants and filamentous pathogens, including fungi and oomycetes, and discusses their role in host–pathogen interactions. We highlight secondary small interfering RNAs of plants as regulators of immune receptor gene expression and executors of host-induced gene silencing in invading pathogens. The current status and prospects of small RNAs trafficking at the host–pathogen interface are discussed. Expected final online publication date for the Annual Review of Phytopathology, Volume 59 is August 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Next-Generation Genetic and Fermentation Technologies for Safe and Sustainable Production of Food Ingredients: Colors and Flavorings

2022 ◽  
Vol 13 (1) ◽  
Author(s):  
Seung-Oh Seo ◽  
Yong-Su Jin
Keyword(s):  
Food Security ◽  
Food Production ◽  
Food Additives ◽  
Strain Engineering ◽  
Current Status ◽  
Annual Review ◽  
Manufacturing Processes ◽  
Publication Date ◽  
Sustainable Operations ◽  
Food Ingredients

A growing human population is a significant issue in food security owing to the limited land and resources available for agricultural food production. To solve these problems, sustainable food manufacturing processes and the development of alternative foods and ingredients are needed. Metabolic engineering and synthetic biology can help solve the food security issue and satisfy the demand for alternative food production. Bioproduction of food ingredients by microbial fermentation is a promising method to replace current manufacturing processes, such as extraction from natural materials and chemical synthesis, with more ecofriendly and sustainable operations. This review highlights successful examples of bioproduction for food additives by engineered microorganisms, with an emphasis on colorants and flavors that are extensively used in the food industry. Recent strain engineering developments and fermentation strategies for producing selected food colorants and flavors are introduced with discussions on the current status and future perspectives. Expected final online publication date for the Annual Review of Food Science and Technology, Volume 13 is March 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Resilience in Urban African American Adolescents: The Protective Enhancing Effects of Neighborhood, Family, and School Cohesion Following Violence Exposure

2016 ◽  
Vol 38 (9) ◽  
pp. 1286-1321 ◽  
Author(s):  
Cara M. DiClemente ◽  
Catherine M. Rice ◽  
Dakari Quimby ◽  
Maryse H. Richards ◽  
Cordelia T. Grimes ◽  
...  
Keyword(s):  
African American ◽  
Youth Development ◽  
Low Income ◽  
African American Adolescents ◽  
Well Being ◽  
Self Esteem ◽  
Positive Outcomes ◽  
School Cohesion ◽  
External Characteristics

Exposure to violence (ETV) poses a serious threat to adolescents’ safety and well-being; however, some adolescents who grow up in such toxic environments are able to thrive due to a combination of internal and external characteristics. The current study examines the role of cohesion across contexts (i.e., family, school, and community) as moderating the relation between ETV and positive internal outcomes characteristic of resilient youth (i.e., ethnic identity, positive affect, and self-esteem) in a sample of low-income, urban, African American adolescents ( N = 269, 60% female) from seventh grade to eighth grade. Results indicated that greater cohesion in each context was directly related to more positive outcomes. Family and neighborhood cohesion additionally served as protective enhancing factors for males exposed to high levels of violence. These findings expand the current research on positive youth development and help locate potential environmental targets for prevention and intervention research.

scholarly journals Using Community-Based Programming to Increase Family Social Support for Healthy Eating among African American Adolescents

2010 ◽  
Vol 5 (3) ◽  
pp. 107-121
Author(s):  
Joel E. Williams ◽  
Sarah F. Griffin ◽  
Amy S. McCune ◽  
Gregory H. Linke
Keyword(s):  
Social Support ◽  
African American ◽  
Youth Development ◽  
Healthy Eating ◽  
Cognitive Theory ◽  
Vegetable Intake ◽  
African American Adolescents ◽  
Low Fat ◽  
Dairy Intake ◽  
Family Social Support

Little is known about emotional and instrumental social support for nutrition behaviors among African-American adolescents. In this paper, we specifically examine intervention effects on emotional, instrumental and total (composite) social support for fruit/vegetable and low-fat dairy intake. Data from a larger intervention, based on Social Cognitive Theory, which was implemented with 38 African-American adolescents and their families to increase fruit/vegetable intake, low-fat dairy intake and physical activity behaviors are presented. One-way ANOVA analyses revealed that intervention participants had positive and significant increases in emotional social support for low-fat dairy intake (P=0.01), total social support for fruit/vegetable intake (P=0.05), and total social support for low-fat dairy intake (P=0.02). Specific recommendations addressing family social support for healthy eating through youth development programming are discussed.

scholarly journals Reproducible Research: A Retrospective

2021 ◽  
Vol 42 (1) ◽  
Author(s):  
Roger D. Peng ◽  
Stephanie C. Hicks
Keyword(s):  
Public Health ◽  
Health Research ◽  
Scientific Discovery ◽  
Scientific Progress ◽  
Original Data ◽  
Public Health Research ◽  
Current Status ◽  
Reproducible Research ◽  
Annual Review ◽  
Publication Date

Advances in computing technology have spurred two extraordinary phenomena in science: large-scale and high-throughput data collection coupled with the creation and implementation of complex statistical algorithms for data analysis. These two phenomena have brought about tremendous advances in scientific discovery but have raised two serious concerns. The complexity of modern data analyses raises questions about the reproducibility of the analyses, meaning the ability of independent analysts to recreate the results claimed by the original authors using the original data and analysis techniques. Reproducibility is typically thwarted by a lack of availability of the original data and computer code. A more general concern is the replicability of scientific findings, which concerns the frequency with which scientific claims are confirmed by completely independent investigations. Although reproducibility and replicability are related, they focus on different aspects of scientific progress. In this review, we discuss the origins of reproducible research, characterize the current status of reproducibility in public health research, and connect reproducibility to current concerns about replicability of scientific findings. Finally, we describe a path forward for improving both the reproducibility and replicability of public health research in the future. Expected final online publication date for the Annual Review of Public Health, Volume 42 is April 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Saving Lives: Recognizing and Intervening with Youth at Risk for Suicide

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Alejandra Arango ◽  
Polly Y. Gipson ◽  
Jennifer G. Votta ◽  
Cheryl A. King
Keyword(s):  
United States ◽  
At Risk ◽  
Suicide Risk ◽  
Empirical Support ◽  
The United States ◽  
Annual Review ◽  
Publication Date ◽  
Evidence Based ◽  
Psychotherapeutic Interventions ◽  
Youth At Risk

Suicide is the second leading cause of death for youth in the United States. Fortunately, substantial advances have been achieved in identifying and intervening with youth at risk. In this review, we first focus on advances in proactive suicide risk screening and psychoeducation aimed at improving the recognition of suicide risk. These strategies have the potential to improve our ability to recognize and triage youth at risk who may otherwise be missed. We then review recent research on interventions for youth at risk. We consider a broad range of psychotherapeutic interventions, including crisis interventions in emergency care settings. Though empirical support remains limited for interventions targeting suicide risk in youth, effective and promising approaches continue to be identified. We highlight evidence-based screening and intervention approaches as well as challenges in these areas and recommendations for further investigation. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 17 is May 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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