scholarly journals Sexual dimorphism in the permeability response of coronary microvessels to adenosine

2005 ◽  
Vol 288 (4) ◽  
pp. H2006-H2013 ◽  
Author(s):  
Virginia H. Huxley ◽  
JianJie Wang ◽  
Stevan P. Whitt

Gender influences volume regulation via several mechanisms; whether these include microvascular exchange, especially in the heart, is not known. In response to adenosine (Ado), permeability ( Ps) to protein of coronary arterioles of female pigs decreases acutely. Whether Ado induces similar Ps changes in arterioles from males or whether equivalent responses occur in coronary venules of either sex has not been determined. Hypotheses that 1) basal Ps properties and 2) Ps responses to vasoactive stimuli are sex independent were evaluated from measures of Ps to two hydrophilic proteins, α-lactalbumin and porcine serum albumin (PSA), in arterioles and venules isolated from hearts of adult male and female pigs. Consistent with hypothesis 1, basal Ps values of both microvessel types were independent of sex. Contrary to hypothesis 2, Ps responses to Ado varied with sex, protein, and vessel type. Confirming earlier studies, Ado induced a ∼20% decrease in Ps to both proteins in coronary arterioles from females. In arterioles from males, Ado did not change Ps for α-lactalbumin ([Formula: see text], 3 ± 13%), whereas Ps for PSA ([Formula: see text]) decreased by 27 ± 8% ( P < 0.005). In venules from females, Ado elevated [Formula: see text] by 44 ± 20% ( P < 0.05), whereas in those from males, Ado reduced [Formula: see text] by 24 ± 5% ( P < 0.05). The variety of outcomes is consistent with transvascular protein and protein-carried solute flux being regulated by multiple sex-dependent mechanisms in the heart and provides evidence of differences in exchange homeostasis of males and females in health and, likely, disease.

Zootaxa ◽  
2012 ◽  
Vol 3177 (1) ◽  
pp. 1 ◽  
Author(s):  
ANIL KUMAR DUBEY ◽  
CHIUN-CHENG KO

Sexual dimorphism is recorded among the puparia of six species of Aleurocanthus from Taiwan, including Aleurocanthuslauriphaga sp.n. from Cinnamomum osmophloeum. A key is provided to the puparia of seven species of this genus knownfrom Taiwan, with illustrations of immature stages and the adult male and female of the new species. The flocculent waxsecretion pattern in the puparia of this new species is atypical amongst Aleurocanthus species. Newly recorded from Tai-wan is A. citriperdus Quaintance & Baker, and the record of A. spinosus (Kuwana) from Taiwan is discussed. A list of recorded host plants of Aleurocanthus species from Taiwan is provided.


1996 ◽  
Vol 19 (2) ◽  
pp. 254-255
Author(s):  
Michael T. Ghiselin

AbstractIn Darwinian terminology, “sexual selection” refers to purely reproductive competition and is conceptually distinct from natural selection as it affects reproduction generally. As natural selection may favor the evolution of sexual dimorphism by virtue of the division of labor between males and females, this possibility needs to be taken very seriously.


Reproduction ◽  
2017 ◽  
Vol 153 (4) ◽  
pp. R133-R149 ◽  
Author(s):  
A E Newell-Fugate

With the increasing knowledge that gender influences normal physiology, much biomedical research has begun to focus on the differential effects of sex on tissue function. Sexual dimorphism in mammals is due to the combined effects of both genetic and hormonal factors. Hormonal factors are mutable particularly in females in whom the estrous cycle dominates the hormonal milieu. Given the severity of the obesity epidemic and the fact that there are differences in the obesity rates in men and women, the role of sex in white adipose tissue function is being recognized as increasingly important. Although sex differences in white adipose tissue distribution are well established, the mechanisms affecting differential function of adipocytes within white adipose tissue in males and females remain largely understudied and poorly understood. One of the largest differences in the endocrine environment in males and females is the concentration of circulating androgens and estrogens. This review examines the effects of androgens and estrogens on lipolysis/lipogenesis, adipocyte differentiation, insulin sensitivity and adipokine production in adipocytes from white adipose tissue with a specific emphasis on the sexual dimorphism of adipocyte function in white adipose tissue during both health and disease.


1978 ◽  
Vol 8 (1) ◽  
pp. 103-105 ◽  
Author(s):  
Lewis Berner

Abstract Study of a series of reared adult male and female mayflies in the genus Asthenopus from the Amazon demonstrated that males had been described by Hagen as A. curtus and females as A. amazonicus. As only a single species is represented by the strongly sexually dimorphic males and females, all should be designated as A. curtus (Hagen) and A. amazonicus (Hagen) is, therefore, a synonym.


2005 ◽  
Vol 84 (2) ◽  
pp. 160-165 ◽  
Author(s):  
N.S. Treister ◽  
S.M. Richards ◽  
M.J. Lombardi ◽  
P. Rowley ◽  
R.V. Jensen ◽  
...  

Sex-related differences exist in the structure and function of the major glands in a variety of species. Moreover, many of these variations appear to be unique to each tissue. We hypothesized that this sexual dimorphism is due, at least in part, to gland-specific differences in gene expression between males and females. Glands were collected from male and female BALB/c mice (n = 5/sex/experiment), and total RNA was isolated. Samples were analyzed for differentially expressed mRNAs with CodeLink microarrays, and data were evaluated by GeneSifter. Our results demonstrate that significant (P < 0.05) sex-related differences exist in the expression of numerous genes in the major salivary glands, and many of these differences were tissue-specific. These findings support our hypothesis that sex-related differences in the salivary glands are due, at least in part, to tissue-specific variations in gene expression.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
C. N. Orish ◽  
B. C. Didia ◽  
H. B. Fawehinmi

Background. Determination of sex is an important concern to the forensic anthropologists as it is critical for individual identification. This study has investigated the existence of sexual dimorphism in the dimensions and the area of the IOA triangle. Methods. A total of 100 adult dry skulls, (78 males; 22 females) from departments of anatomy in Nigerian universities were used for this study. Automatic digital calliper was used for the measurement. Coefficient of variation, correlation, linear regression, percentiles, and sexual dimorphism ratio were computed from the IOA triangle measurements. The IOA triangle area was compared between sexes. Results. The male parameters were significantly (P<0.05) higher than female parameters. The left opistocranium-asterion length was 71.09±0.56 and 61.68±3.35 mm and the right opistocranium-asterion length was 69.73±0.49 and 60.92±2.10 mm for male and female, respectively. A total area of IOA triangle of 1938.88 mm2 and 1305.68 mm2 for male and female, respectively, was calculated. The left IOA indices were 46.42% and 37.40% in males and females, respectively, while the right IOA indices for males and females were 47.19% and 38.87%, respectively. Conclusion. The anthropometry of inion-opistocranium-asterion IOA triangle can be a guide in gender determination of unknown individuals.


2020 ◽  
pp. jeb.235697
Author(s):  
Michael L. Logan ◽  
Lauren K. Neel ◽  
Daniel J. Nicholson ◽  
Andrew J. Stokes ◽  
Christina L. Miller ◽  
...  

If fitness optima for a given trait differ between males and females in a population, sexual dimorphism may evolve. Sex-biased trait variation may affect patterns of habitat use, and if the microhabitats used by each sex have dissimilar microclimates, this can drive sex-specific selection on thermal physiology. Nevertheless, tests of differences between the sexes in thermal physiology are uncommon, and studies linking these differences to microhabitat use or behavior are even rarer. We examined microhabitat use and thermal physiology in two ectothermic congeners that are ecologically similar but differ in their degree of sexual size dimorphism. Brown anoles (Anolis sagrei) exhibit male-biased sexual size dimorphism and live in thermally heterogeneous habitats, whereas slender anoles (Anolis apletophallus) are sexually monomorphic in body size and live in thermally homogeneous habitats. We hypothesized that differences in habitat use between the sexes would drive sexual divergence in thermal physiology in brown anoles, but not slender anoles, because male and female brown anoles may be exposed to divergent microclimates. We found that male and female brown anoles, but not slender anoles, used perches with different thermal characteristics and were sexually dimorphic in thermal tolerance traits. However, field-active body temperatures and behavior in a laboratory thermal arena did not differ between females and males in either species. Our results suggest that sexual dimorphism in thermal physiology can arise from phenotypic plasticity or sex-specific selection on traits that are linked to thermal tolerance, rather than from direct effects of thermal environments experienced by males and females.


2021 ◽  
Vol 18 (3) ◽  
pp. 05-09
Author(s):  
Ayesha Anjum ◽  

Background: Bleeding time is a laboratory test to assess the platelet function. It is dependent on various factors like function of platelets and pathway of coagulation. Clotting time is the time required for a sample of blood to clot in vitro under standard conditions. It is known from previous studies that there is a difference in the bleeding time and clotting time among males and females. The exact reasons for such differences have been postulated, but are insufficient. Therefore the aim of this study is to study and compare the gender differences in bleeding time and clotting time in young male and female subjects. Aims and objectives: The aim of this study is to determine and compare the differences in bleeding time and clotting time in young adult male and female subjects. Materials and Methods: This study was done in the Department of Physiology, Raichur Institute of Medical Sciences, Raichur. Sixty medical students studying in first year M.B.B.S, were selected for the study, out of which thirty were males, and thirty were females. Bleeding time was determined by Duke’s method and Clotting time was determined by Wrights Capillary tube method. Data was analysed using SPSS software. Unpaired ‘t’ test was used for comparing the values. p value less than 0.05 was considered significant. Result: The mean value of bleeding time in males was found to be,127.69±51,02 and in females it was 133.28±44.30. The mean of the CT in males was 212.18±60 and in females it was found to be 257.16±61.00.The mean BT and CT was significantly higher in females as compared to the males. Conclusion: It was found that there are differences in bleeding time and time in males and females, BT and CT were statistically more in females as compared to females.


Foods ◽  
2018 ◽  
Vol 8 (1) ◽  
pp. 8 ◽  
Author(s):  
Pascal Chartrin ◽  
Thierry Bordeau ◽  
Estelle Godet ◽  
Karine Méteau ◽  
Jean-Christian Gicquel ◽  
...  

The technological, nutritional, and sensorial quality of breasts and thighs with drumsticks of turkey male and female breeders was characterized by comparison with breasts and thighs with drumsticks of growing male and female turkeys from the Grademaker line (hybrid turkeys, n = 20 birds per sex and per physiological stage). The breeder turkeys were slaughtered at 397 and 410 days of age and 10.42 and 32.67 kg of body weight for the females and males, respectively. The standard turkeys were slaughtered at 75 and 103 days of age and 5.89 and 13.48 kg of body weight for the females and males, respectively. The differences observed between males and females on one hand and between standard and breeder turkeys on the other hand were mainly induced by differences in slaughter ages and sexual dimorphism on body weight. The meat of female breeders had characteristics close to those of female and male standard turkeys, whereas the meat of male breeders was clearly distinguishable, particularly by displaying lower tenderness and water holding capacity.


2000 ◽  
Vol 278 (4) ◽  
pp. H1177-H1185 ◽  
Author(s):  
Virginia H. Huxley ◽  
Donna A. Williams

Whereas the glycocalyx of endothelial cells has been shown to influence solute flux from capillary microvessels, little is known about its contribution to the movement of macromolecules across the walls of other microvessels. We evaluated the hypothesis that a glycocalyx contributes resistance to protein flux measured in coronary arterioles. Apparent solute permeability ( P s) to two proteins of different size and similar charge, α-lactalbumin (α-lactalb) and porcine serum albumin (PSA), was determined in arterioles isolated from the hearts of 43 female Yucatan miniature swine. P s was assessed in arterioles with an “intact” glycocalyx under control conditions and again after suffusion with adenosine (Ado, 10− 5 M, n = 42 arterioles, N = 29 pigs). In a second set of experiments ( n = 21 arterioles, N = 21 pigs) arteriolar P s was determined before and after perfusion with enzyme (pronase or heparinase), which was used to digest the glycocalyx. P s was assessed a third time on those microvessels after exposure to Ado. Consistent with the hypothesis, P s for PSA ([Formula: see text]) and P sfor α-lactalb ([Formula: see text]) increased from basal levels following enzyme treatment. Subsequent suffusion with Ado, a significant metabolite known to alter coronary vascular smooth muscle tone and permeability, resulted in a significant reduction of basal [Formula: see text] in both untreated and enzyme-treated arterioles. Furthermore, in untreated arterioles, [Formula: see text] was unchanged by Ado suffusion, whereas Ado induced a pronounced reduction in[Formula: see text] of enzyme-treated vessels. These data demonstrate that in intact coronary arterioles an enzyme-sensitive layer, most likely at the endothelial cell surface, contributes significantly to net barrier resistance to solute flux.


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