Fibrinopeptide A after strenuous physical exercise at high altitude

1982 ◽  
Vol 53 (1) ◽  
pp. 40-43 ◽  
Author(s):  
P. Bartsch ◽  
E. K. Schmidt ◽  
P. W. Straub
Keyword(s):  
Physical Exercise ◽  
Degradation Products ◽  
Young Male ◽  
Bicycle Ergometer ◽  
Control Group ◽  
Fibrinopeptide A ◽  
Factor Viii Activity ◽  
Short Term ◽  
Strenuous Physical Exercise ◽  
Significant Difference

To examine hemostasis after physical exercise at altitudes easily accessible to tourists by public transport, 20 young male volunteers were exposed to 3,457 m above sea level. Ten of them were subjected to an exhaustive exercise for about 8 min on a bicycle ergometer. The preexercise samples (n = 20) taken 1 h after arrival showed no significant alteration of coagulation compared with control values at 600 m. After the exercise the clotting times (P less than 0.001) and euglobulin lysis times (P less than 0.001) were shortened, whereas factor VIII activity (P less than 0.001) was elevated. There was, however, no significant difference in fibrinopeptide A levels between the exercise and the control group. Ethanol gelation test remained negative. We found no rise in fibrin(ogen) degradation products and fibrin(ogen) fragment E and thus conclude that there is no evidence for clinically relevant intravascular coagulation after short-term strenuous physical exercise at altitude.

Lack of fibrin formation in exercise-induced activation of coagulation

1979 ◽  
Vol 236 (4) ◽  
pp. H577-H579 ◽  
Author(s):  
A. Vogt ◽  
V. Hofmann ◽  
P. W. Straub
Keyword(s):  
Physical Exercise ◽  
Degradation Products ◽  
Bicycle Ergometer ◽  
Strenuous Exercise ◽  
Thrombin Time ◽  
Fibrinopeptide A ◽  
Lysis Time ◽  
Exercise Period ◽  
Euglobulin Lysis Time ◽  
Exercise Induced

Strenuous physical exercise leads to a significant shortening of blood clotting in various test systems. Such short times are also characteristic of those observed in sedentary patients with thrombosis or disseminated intravascular coagulation, and of those observed in experimental animals after thrombin infusion. The patients exhibit an increase in circulating fibrinopeptide A, which is attributed to thrombin action on circulating fibrinogen, and to an increase of fibrinogen degradation products, which is thought to indicate reactive fibrinolysis. To check whether physical exercise leads to fibrinemia, 10 healthy male volunteers were subjected to strenuous exercise on a bicycle ergometer. Blood samples were taken immediately before and on completion of the exercise period. Despite a significant shortening of the activated partial thromboplastin time, the thrombin time, and the Reptilase time, no increase of fibrinopeptide A could be demonstrated and the ethanol gelation test remained consistently negative. Simultaneously, the euglobulin lysis time was significantly shortened, whereas the fibrin(ogen) degradation products did not increase. The results indicate that the shortening of the coagulation times associated with physical exercise must be explained by mechanisms other than thrombin-mediated conversion of fibrinogen to fibrin.

scholarly journals Physical exercise during pregnancy and its influence in the type of birth

2012 ◽  
Vol 10 (4) ◽  
pp. 409-414 ◽  
Author(s):  
Lílian Cristina da Silveira ◽  
Conceição Aparecida de Mattos Segre
Keyword(s):  
Physical Activity ◽  
Physical Exercise ◽  
Basic Education ◽  
Exercise Program ◽  
Regular Physical Activity ◽  
Control Group ◽  
Significance Level ◽  
Vaginal Deliveries ◽  
Significant Difference ◽  
Primiparous Women

OBJECTIVE: To verify if medium intensity exercise performed during pregnancy can influence in the type of delivery, and to observe compliance to an exercise program among primiparous women with different levels of schooling. METHODS: A study carried out at the Centro de Incentivo ao Aleitamento Materno, in São Sebastiao (SP), between April 7, 2008, and April 14, 2009. A prospective study involving 66 primiparous women who were divided into two groups: an Exercise Group, engaged in regular physical activity during pregnancy, and the Control Group, that did not participate in regular physical activity during the same period. Significance level in this project was 5% (p=0.05). RESULTS: The group that did engage in regular exercise had a higher rate of vaginal deliveries, with a statistically significance difference evaluated by the χ² test (p=0.031). The pregnant women with the highest level of schooling showed greater compliance with the exercise program, with a statistically significant difference (p=0.01736). CONCLUSION: Physical exercise in primiparous women increased the chances of vaginal deliveries, and there was greater compliance with the exercise program among those with a higher level of schooling when compared to those with a basic education.

Comparative study of episiotomy repair: absorbable synthetic versus chromic catgut suture material

2017 ◽  
Vol 6 (6) ◽  
pp. 2186
Author(s):  
Devika Perumal ◽  
Divya Selvaraju
Keyword(s):  
Comparative Study ◽  
Suture Material ◽  
Statistical Significance ◽  
Wound Dehiscence ◽  
Chromic Catgut ◽  
Control Group ◽  
Absorbable Suture ◽  
Perineal Laceration ◽  
Short Term ◽  
Significant Difference

Background: The choice of suture material for repair of episiotomy or perineal laceration is largely of one’s personal preference. Chromic catgut was widely used in most institutions. It now appears that chromic catgut is associated with more postpartum discomfort and hence chromic catgut has been largely replaced by synthetic absorbable materials like polyglactin and polyglycolic acid.Methods: The study was conducted in Institute of Social Obstetrics and Government Kasturba Gandhi Hospital, Chennai. This is a prospective, comparative study involving two groups. The use of a rapidly absorbing form of synthetic absorbable suture material, in the repair of episiotomy or perineal laceration in 100 patients during the study period February 2012 to July 2012, were simultaneously compared with the traditional natural absorbable suture material.Results: With the use of rapidly absorbing polyglactin 910, there was a significant reduction (p=0.000) in the short-term pain, 19 compared to 80 in the control group. With regard to wound dehiscence and the need for resuturing, there was statistically significant difference in the control group (15%) compared to the study group (0%). There was no statistical significance between the two groups in terms of dyspareunia (12.4% vs 10.7%).Conclusions: Fast-absorbing form of Polyglactin seems to be effective in reducing some of the morbidity associated with perineal repair following childbirth. There was significant reduction in the short-term pain and the need for analgesia. The incidence of wound dehiscence was markedly reduced.

scholarly journals Moderate Intensity of Physical Exercise increased Β (Beta) Cell and Size of Langerhans Islets in Streptozotocin Induced Diabetes Mellitus Rats

2019 ◽  
Vol 1 (2) ◽  
pp. 52
Author(s):  
Sarah M Nurdin ◽  
Nuniek Nugraheni ◽  
Mei Wulan
Keyword(s):  
Diabetes Mellitus ◽  
Physical Exercise ◽  
Beta Cell ◽  
Moderate Intensity ◽  
Induction Treatment ◽  
Control Group ◽  
Β Cell ◽  
Moderate Intensity Exercise ◽  
Langerhans Islets ◽  
Significant Difference

Background: The death of β cells Langerhans islets in Diabetes Mellitus (DM) can cause  loss of Langerhans islet function and worsen the progression of DM. Physical exercise plays a major part in DM treatment.Aim: to observe the effect of moderate intensity exercise to β (beta) cell numbers and Langerhans islets area size in Streptozotocin (STZ) induced diabetes in rats.Methods: Thirty adult male Wistar rats (Rattusnorvegicus) divided into 3, Group 1 as the control, Group 2 received 35 mg/kg streptozotocin induction treatment, Group 3 received 35 mg/kg streptozotocin induction and physical exercise, swimming, with moderate intensity 70% from the swimming maximal ability, 9% of body weight load, 4 times a week for 4 weeks. Datas collected were in the form of histopathology slide of pancreatic tissue after receiving treatment for 28 days.Results: There are significant differences of β-cell pancreas number between group K1 and K2 (p<0,001), group K2 and to K3 (p<0,001). No significant difference between group K1 and K3 (p=0,102). The Langerhans islets area sizes of pancreas tissue between group K1, K2, and K3 are significantly different (p<0,001).Conclusion: This study shows moderate-intensity physical exercise can increase the number of β cell and average area size of Langerhans islets. The effect of physical exercise depends on the intensity of exercise and the capacity of pancreatic function left of the diabetic.

scholarly journals Effect of Carnatic Music Listening Training on Speech in Noise Performance in Adults

2021 ◽  
Vol 25 (1) ◽  
pp. 22-26
Author(s):  
Raksha Amemane ◽  
Archana Gundmi ◽  
Kishan Madikeri Mohan
Keyword(s):  
Repeated Measures ◽  
Functional Organization ◽  
Control Group ◽  
Music Listening ◽  
Noise Performance ◽  
Short Term ◽  
Speech In Noise ◽  
Carnatic Music ◽  
Significant Difference ◽  
And Control

Background and Objectives: Music listening has a concomitant effect on structural and functional organization of the brain. It helps in relaxation, mind training and neural strengthening. In relation to it, the present study was aimed to find the effect of Carnatic music listening training (MLT) on speech in noise performance in adults.Subjects and Methods: A total of 28 participants (40-70 years) were recruited in the study. Based on randomized control trial, they were divided into intervention and control group. Intervention group underwent a short-term MLT. Quick Speech-in-Noise in Kannada was used as an outcome measure.Results: Results were analysed using mixed method analysis of variance (ANOVA) and repeated measures ANOVA. There was a significant difference between intervention and control group post MLT. The results of the second continuum revealed no statistically significant difference between post training and follow-up scores in both the groups.Conclusions: In conclusion short-term MLT resulted in betterment of speech in noise performance. MLT can be hence used as a viable tool in formal auditory training for better prognosis.

PENGARUH MENGKONSUMSI GULA AREN (Arenga pinnata) SEBELUM OLAHRAGA TERHADAP DAYA TAHAN OTOT

2019 ◽  
Vol 1 (1) ◽  
pp. 20
Author(s):  
Cecep Muhammad Alawi ◽  
Hamidie Ronald Daniel Ray
Keyword(s):  
Physical Exercise ◽  
Significant Influence ◽  
The Body ◽  
Control Group ◽  
Muscular Endurance ◽  
Control Group Design ◽  
Squat Jump ◽  
Jump Test ◽  
Significant Difference ◽  
Palm Sugar

Two kinds of carbohydrates that are used with the body as energy, is blood glucose and muscular glycogen. Savings glycogen in muscular is one of the factors that is affecting muscular endurance when physical exercise. The aim of this study is to find out the significant influence of consuming palm sugar to muscular endurance before physical exercise. The method that is used in this study is to experiment with design pretest-posttest control group design. Total of sample of this study is 18 trained mans that is divided into three groups. The first experiment group is given palm sugar that is dissolved in water, the second experiment group is given sugar that is dissolved in water, and the control group is given mineral water. The instrument of this study is used push up test, sit up test, and squat jump test to measures the upper muscular endurance, middle, and bottom. All of the samples have done pretest and posttest in different day. When posttest, all of the sample is consumed beverage based on the treatment 30 minutes before do the posttest. Data analysis by Paired Sample t-test and continued by One Way ANOVA to see the influence and comparison between groups. The result of this study has showed that there is a significant difference, the raising of muscular endurance is proved by the score (sig) 0.00>0.05, which the highest increasing is the palm sugar group. Therefore, it could be concluded that there is a significant influence of consuming palm sugar to muscular endurance before physical exercise.

scholarly journals INTERVENSI PROGRESSIVE MUSCLE RELAXATION LEBIH MENURUNKAN TEKANAN DARAH DARI PADA SLOW STROKE BACK MASSAGE PADA PASIEN HIPERTENSI DERAJAT I YANG MENGONSUMSI OBAT ANTI HIPERTENSI DI BADUNG

2019 ◽  
Author(s):  
Ni Komang Ayu Juni Antari ◽  
Alex Pangkahila ◽  
Muh. Ali Imron ◽  
I Putu Adiartha Griadhi ◽  
Luh Made Indah Sri Handari Adiputra ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Physical Exercise ◽  
Muscle Relaxation ◽  
Progressive Muscle Relaxation ◽  
Control Group ◽  
Relaxation Techniques ◽  
Group I ◽  
Significant Difference ◽  
Group 2 ◽  
Back Massage

ABTSRACT Introduction: Physical exercise as anticipate of hypertension along with nutrition and medicines. One of physical exercise that can be applicated here is relaxation techniques which is showed positive impact in decreased blood pressure. Objective: Determine the difference between PMR intervention with SSBM intervention to reduce blood pressure for grade I hypertension patients whose consumed anti-hypertension medicine in badung regency. Methods: Experimental method Pre and post-test control group design and used 24 subjects, divided in to 2 groups, in which the experimental group I (n=12) received progressive muscle relaxation (PMR) while the treatment group 2 (n=12) received slow stroke back massage (SSBM). Intervention is given 3 times a week for 4 weeks. This study was using simple random sampling. Blood pressure was measured by sphygmomanometer and stethoscope. Result: Independent Sample T-test showed there was significant difference between Group 1 and Group 2 which (p<0.05) for systolic and diastolic blood pressure. Conclusion: Progressive muscle relaxation intervention decrease blood pressure more than slow stroke back massage intervention in patients grade I hypertension whose consumed anti-hypertension medicine in Badung Regency.Keywords: progressive muscle relaxation, slow stroke back massage, grade I hypertension, blood pressure

scholarly journals Efficacy of Surgery Combined with Autologous Bone Marrow Stromal Cell Transplantation for Treatment of Intracerebral Hemorrhage

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Jianxin Zhu ◽  
Yilei Xiao ◽  
Zhongmin Li ◽  
Fabin Han ◽  
Taiwu Xiao ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Barthel Index ◽  
Autologous Bone Marrow ◽  
Control Group ◽  
Short Term ◽  
System Disease ◽  
Therapeutic Benefits ◽  
Neurologic Impairment ◽  
Significant Difference

Bone marrow stromal cells (BMSCs) may differentiate into nerve cells under a certain condition; however, the clinical application for treating nervous system disease remains unclear. The aim is to assess the safety profile, feasibility, and effectiveness of surgery combined with autologous BMSCs transplantation for treating ICH. 206 ICH patients who had received surgical procedure were divided into transplantation (n=110) or control group (n=96). For transplantation group, BMSCs were injected into the perihemorrhage area in the base ganglia through an intracranial drainage tube 5.5 (3.01–6.89) days after surgery, followed by a second injection into the subarachnoid space through lumbar puncture 4 weeks later. Neurologic impairment and daily activities were assessed with National Institute Stroke Scale (NIHSS), Barthel index, and Rankin scale before transplantation and 6 months and 12 months after transplantation. Our results revealed that, compared with control group, NIHSS score and Rankin scale were both significantly decreased but Barthel index was increased in transplantation group after 6 months. Interestingly, no significant difference was observed between 12 months and 6 months. No transplantation-related adverse effects were investigated during follow-up assessments. Our findings suggest that surgery combined with autologous BMSCs transplantation is safe for treatment of ICH, providing short-term therapeutic benefits.

Moderate Intensity of Physical Exercise increased Β (Beta) Cell and Size of Langerhans Islets in Streptozotocin Induced Diabetes Mellitus Rats

2019 ◽  
Vol 1 (2) ◽  
pp. 52
Author(s):  
Sarah M Nurdin ◽  
Nuniek Nugraheni ◽  
Mei Wulan
Keyword(s):  
Diabetes Mellitus ◽  
Physical Exercise ◽  
Beta Cell ◽  
Moderate Intensity ◽  
Induction Treatment ◽  
Control Group ◽  
Β Cell ◽  
Moderate Intensity Exercise ◽  
Langerhans Islets ◽  
Significant Difference

Background: The death of β cells Langerhans islets in Diabetes Mellitus (DM) can cause  loss of Langerhans islet function and worsen the progression of DM. Physical exercise plays a major part in DM treatment.Aim: to observe the effect of moderate intensity exercise to β (beta) cell numbers and Langerhans islets area size in Streptozotocin (STZ) induced diabetes in rats.Methods: Thirty adult male Wistar rats (Rattusnorvegicus) divided into 3, Group 1 as the control, Group 2 received 35 mg/kg streptozotocin induction treatment, Group 3 received 35 mg/kg streptozotocin induction and physical exercise, swimming, with moderate intensity 70% from the swimming maximal ability, 9% of body weight load, 4 times a week for 4 weeks. Datas collected were in the form of histopathology slide of pancreatic tissue after receiving treatment for 28 days.Results: There are significant differences of β-cell pancreas number between group K1 and K2 (p<0,001), group K2 and to K3 (p<0,001). No significant difference between group K1 and K3 (p=0,102). The Langerhans islets area sizes of pancreas tissue between group K1, K2, and K3 are significantly different (p<0,001).Conclusion: This study shows moderate-intensity physical exercise can increase the number of β cell and average area size of Langerhans islets. The effect of physical exercise depends on the intensity of exercise and the capacity of pancreatic function left of the diabetic.

scholarly journals Effect of Different Media on Short Term Storage of Leaping Mullet (Liza saliens (Risso, 1810)) Sperm

2020 ◽  
Vol 8 (4) ◽  
pp. 996-1000
Author(s):  
Serhat Engin ◽  
Muammer Kürşat Fırat ◽  
Osman Özden ◽  
Cüneyt Suzer ◽  
Müge Hekimoğlu ◽  
...  
Keyword(s):  
Sperm Quality ◽  
Control Group ◽  
Natural Seawater ◽  
Short Term ◽  
Liza Saliens ◽  
Seawater Salinity ◽  
Significant Difference ◽  
Term Storage ◽  
Quality Variation ◽  
Motility Rate

The present study aimed to evaluate the activation characteristics of the leaping mullet spermatozoa and diluted with four different media (D1, D2, D3, D4) for 250 h at 4±2°C. The semen was collected from nine wild fish in Homa Lagoon, İzmir, Turkey in July, during reproductive season. In each trial (n = 9), semen samples were collected and mixed to reduce sperm quality variation to obtain the required gametes for the experiment. The semen was activated with natural seawater (salinity of 34, pH 7.9 and 4±2°C) to determine: motility time, motility rate and viability of sperm. Dilution with inactivation media 1:3 increased motility time of diluted semen than control group. At the end of the experiment, no significant difference was found for the duration of survival in the D2 and D4 groups. The highest survival rate was found in D2 group.

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