Wheel running of kangaroo rats, Dipodomys merriami, as related to food deprivation and body composition

1978 ◽  
Vol 44 (1) ◽  
pp. 17-20 ◽  
Author(s):  
D. B. Dill ◽  
L. F. Soholt ◽  
J. D. Morris
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Body Weight ◽  
Food Deprivation ◽  
Body Fat ◽  
Wheel Running ◽  
Initial Amount ◽  
Kangaroo Rats ◽  
Dipodomys Merriami ◽  
Percentage Of Body Fat

Kangaroo rats deprived of food ran themselves to death in 48 h in wheel cages. Despite the loss of 14.5% of body weight the ratio of water to protein was the same after the run as it was in control rats. Metabolic measurements at rest and in the running wheel and weight loss in the 48-h run were used to estimate fuels used and water expended. Two-thirds of the initial amount of fat and 9% of the protein were metabolized. The terminal mean percentage of body fat was about twice that observed in rats trapped in the spring of 1967, when seed production was low: death in the 48-h run could not have been due to depletion of body fat alone. The powerful activity drive seen in hungary kangaroo rats presumably is intensified in dry years when food is scarce and may deplete their reserves enough to result in death from starvation.

scholarly journals Step-Defined Physical Activity Is Associated With Weight Loss and Changes in Body Composition and Fat Distribution in Response to Diet Interventions: The POUNDS Lost Trial

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 1259-1259
Author(s):  
Qiaochu Xue ◽  
Xiang Li ◽  
Hao Ma ◽  
Tao Zhou ◽  
Yoriko Heianza ◽  
...  
Keyword(s):  
Physical Activity ◽  
Weight Loss ◽  
Body Composition ◽  
Body Weight ◽  
Body Fat ◽  
Fat Distribution ◽  
Tissue Mass ◽  
Adipose Tissue Mass ◽  
Fat Composition ◽  
Protein Diets

Abstract Objectives To examine whether objectively measured physical activity (PA) is associated with weight loss and changes in body composition and fat distribution in response to weight-loss diet interventions. Methods This study included 535 overweight or obese participants randomly assigned to 4 weight-loss diets varying in macronutrient intake with physical activity measured objectively with pedometers in the POUNDS Lost trial. The associations of step defined PA or the changes in PA with the changes in obesity measurements including body weight (BW), waist circumference (WC), body fat composition assessed by the dual-energy X-ray absorptiometry (DEXA) scans, body fat distribution assessed by the computed tomography (CT) were examined at the 6 and 24 months. We also examined whether the associations were modified by diet interventions. Results The increase of step-defined PA was significantly predictive of weight loss and decrease in all measurements of body fat composition and distribution in response to diet interventions over 24 months (P < 0.0001 for all). We also observed significant inverse associations of changes in PA with changes in BW (P < 0.0001), WC (P < 0.0001), body fat composition (P < 0.05 for total fat, total lean, total fat mass %, and trunk fat %) and fat distribution (P < 0.05 for total adipose tissue mass (TAT), visceral adipose tissue mass (VAT), deep subcutaneous adipose tissue mass (DSAT)) from baseline to 6 months, when the maximum weight loss was achieved. Dietary fat or protein intake modified the associations between changes in PA and changes in body weight and waist circumference over 24 months; greater reduction in these measures was observed in participants with high-fat or low-protein diets than those in the low-fat or high-protein diets (P interaction < 0.05 for all). Conclusions Our results indicate that objectively measured PA is inversely related to the changes in body weight, body composition, and fat distribution in response to weight-loss diets, and such relation is more evident in people with high-fat or low-protein diets. Funding Sources The study was supported by grants from the National Heart, Lung, and Blood Institute, the National Institute of Diabetes and Digestive and Kidney Diseases, the Fogarty International Center, and Tulane Research Centers of Excellence Awards.

scholarly journals Changes in body composition after thermal injury in the rat

1979 ◽  
Vol 42 (3) ◽  
pp. 367-375 ◽  
Author(s):  
G. A. Al Shamma ◽  
C. C. Goll ◽  
T. B. Baird ◽  
J. Broom ◽  
G. A. Nicholas ◽  
...  
Keyword(s):  
Weight Loss ◽  
Wound Healing ◽  
Body Composition ◽  
Body Weight ◽  
Food Intake ◽  
Body Fat ◽  
Wistar Rats ◽  
Thermal Injury ◽  
Energy Deficit ◽  
Male Wistar Rats

1. The effects on body composition, measured by direct techniques, of a controlled 25% body-surfacearea thermal injury have been studied in two groups of forty male Wistar rats.2. The extent of weight loss in the animals was directly related to their energy deficit resulting from a combination of injury, food intake and rate of wound healing.3. Body fat proved the most labile source of tissue energy, decreasing to a minimum of approximately 30 g/kg body-weight.4. Relationships between water and fat, and water and protein seen in control animals were not significantly different in the traumatized group.

Effect of environmental temperature on hamster body fat composition

1964 ◽  
Vol 19 (5) ◽  
pp. 863-867 ◽  
Author(s):  
Arthur M. Kodama ◽  
Nello Pace
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Body Weight ◽  
Body Fat ◽  
Environmental Temperature ◽  
Caloric Intake ◽  
Body Weight Loss ◽  
Fat Content ◽  
The Body ◽  
Body Fat Content

Body fat content and the melting point and fatty acid composition of body fat of hamsters exposed to 35, 27, 20, 15, 10, and 6 C for 2 weeks were determined. The relationship between exposure temperature and body fat content and composition resembled that between environmental temperature and metabolic rate. Below the critical temperature, there was a progressive decrease in total body fat content and melting point accompanied by a decrease in the mole fraction of palmitic acid and an increase in the mole fraction of oleic acid. The softening of body fat in cold-exposed animals appears to be the result of an increased mobilization of depot fat in response to a higher metabolic rate in the cold, a mobilization which is at least partially selective with respect to individual fatty acids or triglycerides. Examination of changes in whole body composition revealed that 72% of the loss in body weight of hamsters exposed to 6 C was due to a decrease in body fat content. In contrast, the decrease in body fat content accounted for only 28% of the body weight loss of pair-fed hamsters kept at 27 C on reduced caloric intake to match the body weight loss experienced by cold-exposed animals. It appears, therefore, that cold exposure induces a more effective fat depot mobilization than does reduced caloric intake. heat exposure; cold exposure; body composition Submitted on February 3, 1964

scholarly journals Hydration status, body composition, and anxiety status in aeronautical military personnel from Spain: a cross-sectional study

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Alejandra Carretero-Krug ◽  
Natalia Úbeda ◽  
Carlos Velasco ◽  
Juan Medina-Font ◽  
Trinidad Trujillo Laguna ◽  
...  
Keyword(s):  
Body Composition ◽  
Water Balance ◽  
Body Fat ◽  
Water Intake ◽  
Military Personnel ◽  
Hydration Status ◽  
Total Water ◽  
Percentage Of Body Fat ◽  
Urine Color ◽  
Total Water Intake

Abstract Background An adequate hydration status is critical to ensure efficiency during mental and physical activities. Our goal was to assess the hydration status of a Spanish group of aeronautical military men and to determine the association of hydration status with body composition and anxiety. Methods A total of 188 men were evaluated through a validated hydration questionnaire, anthropometric and biochemical parameters, and an anxiety questionnaire. Based on these methods, the criteria of hydration were established. Results Of the total sample, 81% met the hydration criteria (urine color = well hydrated, water balance ≥ 0 ml, and total water intake/weight ≥ 35 ml/kg), and 19% did not meet the hydration criteria (urine color = not sufficiently hydrated or dehydrated, water balance < 0 ml, and total water intake/weight < 35 ml/kg). Subjects not meeting the hydration criteria had lower urine pH, negative water balance, and lower water intake. The latter also had higher anxiety status (score = 4 vs. 3, P = 0.026), weight [(84.7 ± 10.5) vs. (80.5 ± 10.2) kg], body mass index [(26.3 ± 3.1) vs. (25.2 ± 2.8)]kg/m2, body fat [(22.3 ± 5.6) vs. (18.3 ± 6.5)] %, urine specific gravity, and urine color. Using a logistic binary regression model, hydration status was related significantly with the percentage of body fat (P = 0.004), but no relation was found with age, comorbidities, or medications. Furthermore, total water intake/weight was positively correlated with percentage of body water (r = 0.357, P = 0.000) and negatively with body fat (kg) (r = − 0.427, P = 0.000), percentage of body fat (r = − 0.405, P = 0.000), and waist/hip ratio (r = − 0.223, P = 0.002). Based on a linear regression model, total water intake/weight was related significantly with percentage of body fat (P = 0.001) and percentage of body water content (P = 0.035). No relation was found, however, with waist/hip ratio, age, comorbidities, or medications. Conclusions These findings all suggest a relationship between hydration status and body composition but also set the bases for future studies that relate hydration status and anxiety status. These results can be used to improve the hydration status and body composition of military personnel.

scholarly journals European Guidelines for Obesity Management in Adults with a Very Low-Calorie Ketogenic Diet: A Systematic Review and Meta-Analysis

Obesity Facts ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 222-245
Author(s):  
Giovanna Muscogiuri ◽  
Marwan El Ghoch ◽  
Annamaria Colao ◽  
Maria Hassapidou ◽  
Volkan Yumuk ◽  
...  
Keyword(s):  
Systematic Review ◽  
Weight Loss ◽  
Body Composition ◽  
Body Weight ◽  
Side Effects ◽  
Ketogenic Diet ◽  
Meta Analysis ◽  
Dietary Treatment ◽  
Obesity Management ◽  
Weight Loss Interventions

<b><i>Background:</i></b> The very low-calorie ketogenic diet (VLCKD) has been recently proposed as an appealing nutritional strategy for obesity management. The VLCKD is characterized by a low carbohydrate content (&#x3c;50 g/day), 1–1.5 g of protein/kg of ideal body weight, 15–30 g of fat/day, and a daily intake of about 500–800 calories. <b><i>Objectives:</i></b> The aim of the current document is to suggest a common protocol for VLCKD and to summarize the existing literature on its efficacy in weight management and weight-related comorbidities, as well as the possible side effects. <b><i>Methods:</i></b> This document has been prepared in adherence with Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. Literature searches, study selection, methodology development, and quality appraisal were performed independently by 2 authors and the data were collated by means of a meta-analysis and narrative synthesis. <b><i>Results:</i></b> Of the 645 articles retrieved, 15 studies met the inclusion criteria and were reviewed, revealing 4 main findings. First, the VLCKD was shown to result in a significant weight loss in the short, intermediate, and long terms and improvement in body composition parameters as well as glycemic and lipid profiles. Second, when compared with other weight loss interventions of the same duration, the VLCKD showed a major effect on reduction of body weight, fat mass, waist circumference, total cholesterol and triglyceridemia as well as improved insulin resistance. Third, although the VLCKD also resulted in a significant reduction of glycemia, HbA1c, and LDL cholesterol, these changes were similar to those obtained with other weight loss interventions. Finally, the VLCKD can be considered a safe nutritional approach under a health professional’s supervision since the most common side effects are usually clinically mild and easily to manage and recovery is often spontaneous. <b><i>Conclusions:</i></b> The VLCKD can be recommended as an effective dietary treatment for individuals with obesity after considering potential contra-indications and keeping in mind that any dietary treatment has to be personalized. <b><i>Prospero Registry:</i></b> The assessment of the efficacy of VLCKD on body weight, body composition, glycemic and lipid parameters in overweight and obese subjects: a meta-analysis (CRD42020205189).

scholarly journals Effect of Mixed Nuts on Body Weight and Composition, and Gut Microbiome (P08-054-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Shih Lung Woo ◽  
Dina Ben-Nissan ◽  
Zahra Ezzat-Zadeh ◽  
Jieping Yang ◽  
Lijun Zhang ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Body Weight ◽  
Gut Microbiome ◽  
Plasma Lipids ◽  
Plasma Lipid ◽  
Healthy Weight ◽  
Weight Changes ◽  
Fecal Microbiome ◽  
Tree Nuts

Abstract Objectives This study was designed to assess the effects of mixed nut consumption on body weight and composition, and gut microbiome in obese individuals. Primary outcome was change in body weight and composition. Secondary outcomes include gut microbiome composition, inflammatory markers, and plasma lipids. Methods The reported results are from an interim analysis (n = 50) of a randomized, placebo controlled, parallel study. Total enrollment target is 154 overweight/obese subjects (BMI 27–35 kg/m2). Participants were randomly assigned to consume either 1.5oz mixed tree nuts or pretzels with equal calorie content daily for 24 weeks. The study included a 12-week weight loss phase (500 kcal per day less than total daily energy expenditure), followed by a 12-week weight maintenance phase. Body composition, fasting blood, and stool samples were collected at baseline, week 12 and 24. Body composition, and vitals were analyzed, whereas plasma lipid profile, fecal microbiome, and microbiome metabolites analysis is still pending. Results At week 12, subjects from both the pretzel (n = 15, 10 dropouts; P = 0.009) and nut group (n = 22, 3 dropouts; P = 0.038) lost significant amount of weight. The trend of weight changes did not differ between groups (P = 0.530). Subjects from both groups were able to sustain weight loss through 24 weeks (pretzel: 81.43 ± 3.85 kg at baseline vs. 79.43 ± 4.08 kg at week 24, P = 0.028; nut: 84.26 ± 3.78 kg at baseline vs. 82.38 ± 3.72 kg at week 24, P = 0.026). At week 12, fat mass in both groups was significantly decreased (pretzel: P = 0.002; nut: P = 0.012). The trend of fat changes did not differ between groups (P = 0.547). Subjects from both groups were able to sustain fat loss through 24 weeks (pretzel: 30.84 ± 1.75 kg at baseline vs. 29.25 ± 2.12 kg at week 24, P = 0.024; nut: 31.51 ± 1.56 kg vs 30.21 ± 1.81 kg at week 24, P = 0.04). Muscle mass, and blood pressure were not significantly different between both groups. Conclusions Our data suggested that tree nuts could be consumed as part of a healthy weight loss meal plan without concern of causing weight gain. Further analysis of the remaining samples is needed to confirm results. Due to higher dropouts in the pretzel group, future intention-to-treat analysis is also needed to eliminate bias. Funding Sources This study is supported by the International Tree Nut Council.

scholarly journals Uric acid is associated with adiposity factors, especially with fat mass reduction during weight loss in obese children and adolescents

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Yang Niu ◽  
Xue-lin Zhao ◽  
Hui-juan Ruan ◽  
Xiao-meng Mao ◽  
Qing-ya Tang
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Uric Acid ◽  
Children And Adolescents ◽  
Body Fat ◽  
Fat Mass ◽  
Dietary Control ◽  
Obese Children ◽  
Fat Percentage ◽  
Before And After

Abstract Background Current adult studies suggest that uric acid (UA) is associated with body fat, but the relationship in obese children is unclear. Thus, we aim to evaluate the association between uric acid and body composition of obese children. Methods A total of 79 obese children were included in this study, and 52 children (34 boys and 18 girls) underwent a 6-week weight loss camp, including 34 boys and 18 girls. Six-week weight-loss interventions were performed on all participants through aerobic exercise and appropriate dietary control. Laboratory tests and body composition were collected before and after the intervention. Results Before the intervention, correlation analysis demonstrated that uric acid was positively correlated with height, weight, body mass index (BMI), waist circumference, hip circumference, fat mass (FM), and free fat mass (FFM) with adjusting for age and gender (P < 0.05). After 6 weeks of intervention, the participants gained 3.12 ± 0.85 cm in height, body fat percentage decreased by 7.23 ± 1.97%, and lost 10.30 ± 2.83 kg in weight. Univariate and multivariate analysis indicated that uric acid at baseline was associated with FM reduction during weight loss (P < 0.05). Conclusions This study is the first report that uric acid is associated with BMI and FM, and may play an important role in the reduction of FM during weight loss in obese children and adolescents. The interaction between UA and adiposity factors and its underlying mechanisms need to be further explored. Trial registration This study was registered in Clinical Trials.gov (NCT03490448) and approved by the Ethics Committee of Xinhua Hospital, Shanghai Jiao Tong University School of Medicine.

scholarly journals Parent-of-origin effects on voluntary exercise levels and body composition in mice

2010 ◽  
Vol 40 (2) ◽  
pp. 111-120 ◽  
Author(s):  
Scott A. Kelly ◽  
Derrick L. Nehrenberg ◽  
Kunjie Hua ◽  
Ryan R. Gordon ◽  
Theodore Garland ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Fat ◽  
Wheel Running ◽  
Voluntary Exercise ◽  
Phenotypic Variance ◽  
In Utero Environment ◽  
Dependent Activity ◽  
Health Related ◽  
Parent Of Origin ◽  
Origin Effects

Despite the health-related benefits of exercise, many people do not engage in enough activity to realize the rewards, and little is known regarding the genetic or environmental components that account for this individual variation. We created and phenotyped a large G4 advanced intercross line originating from reciprocal crosses between mice with genetic propensity for increased voluntary exercise (HR line) and the inbred strain C57BL/6J. G4 females (compared to males) ran significantly more when provided access to a running wheel and were smaller with a greater percentage of body fat pre- and postwheel access. Change in body composition resulting from a 6-day exposure to wheels varied between the sexes with females generally regulating energy balance more precisely in the presence of exercise. We observed parent-of-origin effects on most voluntary wheel running and body composition traits, which accounted for 3–13% of the total phenotypic variance pooled across sexes. G4 individuals descended from progenitor (F0) crosses of HR♀ and C57BL/6J♂ ran greater distances, spent more time running, ran at higher maximum speeds/day, and had lower percent body fat and higher percent lean mass than mice descended from reciprocal progenitor crosses (C57BL/6J♀ × HR♂). For some traits, significant interactions between parent of origin and sex were observed. We discuss these results in the context of sex dependent activity and weight loss patterns, the contribution of parent-of-origin effects to predisposition for voluntary exercise, and the genetic (i.e., X-linked or mtDNA variations), epigenetic (i.e., genomic imprinting), and environmental (i.e., in utero environment or maternal care) phenomena potentially modulating these effects.

Effects of a weight loss program on body composition and the metabolic profile in obese postmenopausal women displaying various obesity phenotypes: a MONET group study

2015 ◽  
Vol 40 (7) ◽  
pp. 695-702 ◽  
Author(s):  
Eve Normandin ◽  
Eric Doucet ◽  
Rémi Rabasa-Lhoret ◽  
Martin Brochu
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Postmenopausal Women ◽  
Body Fat ◽  
Metabolic Profile ◽  
Fat Distribution ◽  
Weight Loss Program ◽  
Glucose Disposal ◽  
Fasting Insulin ◽  
Secondary Analyses

Obesity is a heterogeneous condition, since the metabolic profile may differ greatly from one individual to another. The objective of this study was to compare the effect of a 6-month diet-induced weight loss program on body composition and the metabolic profile in obese individuals displaying different obesity phenotypes. Secondary analyses were done on 129 obese (% body fat: 46% ± 4%) postmenopausal women (age: 57 ± 4 years). Outcome measures included body composition, body fat distribution, glucose homeostasis, fasting lipids, and blood pressure. Obesity phenotypes were determined based on lean body mass (LBM) index (LBMI = LBM/height2) and visceral fat (VF) accumulation, as follows: 1, lower VF and lower LBMI (n = 35); 2, lower VF and higher LBMI (n = 19); 3, higher VF and lower LBMI (n = 14); and 4, higher VF and higher LBMI (n = 61). All groups had significantly improved measures of body composition after the intervention (P < 0.0001). Greater decreases in LBM and LBMI were observed in the higher LBMI groups than in the lower LBMI groups (P < 0.0001). Similarly, decreases in VF were greater in the higher VF groups than in the lower VF groups (P < 0.05). Overall, fasting insulin levels and glucose disposal improved following the intervention, with higher LBMI groups showing a trend for greater improvements (P = 0.06 and 0.07, respectively). Overall, no difference was observed among the different obesity phenotypes regarding improvements in the metabolic profile in response to weight loss. Individuals displaying higher VF or higher LBMI at baseline experienced significantly greater decreases for these variables after the intervention.

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